New Clinical Trials for Smoking Cessation

Enroll in a Clinical Trial for Smoking CessationThere are currently 46 million smokers in the U.S. and 47 million ex smokers. Over the past several decades startling information about the dangers of smoking helped start a movement that led to smoking being banned from more and more public places.

Smokers who could once smoke anywhere can now smoke almost nowhere. There are ongoing smoking cessation clinical trials to help those who struggle with this addiction. Smoking cessation clinical research is vital to help people quit and begin to reduce the devastating health and financial costs of smoking.

What is Smoking Cessation?

Smoking cessation (quitting) is the process of slowly reducing the amount of smoke inhaled over a certain amount of time. While mainly used in the case of cigarettes and nicotine, smoking cessation can be talked about as relating to any type of tobacco. Smoking becomes a physical addiction and a psychological dependency. Most smokers who attempt to quit will do so many times before they are successful. Up to ¾ of smokers do eventually quit with no help. The gradual reduction of smoking cessation lessens the severity of withdrawal symptoms and attempts to make the process more bearable.

Smoking Cessation Treatments

There are several products on the market today to help with smoking cessation treatments. These include nicotine replacement therapies (NRTs). NRTs come in the form of nicotine patches, gums, lozenges, and sprays. They help slowly reduce a person’s exposure to nicotine over time. There are also several medications available to help smokers quit. These include antidepressants such as Zyban and Chantix. These drugs aim to reduce cravings for cigarettes. Non-medical smoking cessation treatments include the smoker gradually reducing the amount they smoke. In recent decades there has been a huge shift in society in the acceptance of smoking. People are also more educated about the dangers of second hand smoke to non-smokers.

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We've found
408 Smoking Cessation
clinical trials

Pulmonary / Respiratory Diseases Clinical Trial
Smoking Cessation Clinical Trial
Status: Enrolling
mi
from
DeLand, FL
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Pulmonary / Respiratory Diseases Clinical Trial
Smoking Cessation Clinical Trial
Status: Upcoming
mi
from
DeLand, FL
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Pulmonary / Respiratory Diseases Clinical Trial
Investigating Mucinase Activity in Airway Disease
Status: Enrolling
Updated: 11/12/2015
mi
from
San Francisco, CA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Screening Protocol for Research Participants
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Catonsville, MD
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Pulmonary / Respiratory Diseases Clinical Trial
Examining a Text Message Intervention for Smoking Cessation
Status: Enrolling
Updated: 4/25/2012
mi
from
Providence, RI
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Cardiopulmonary Disease Clinical Trial
Effects of Secondhand Smoke on Flight Attendant Health
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
San Francisco, CA
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Advanced Cancer of the Head and Neck Clinical Trial
Olaparib With Cetuximab & Radiation Therapy in Head & Neck Squamous Cell Carcinomas in Patients With Smoking Histories
Status: Enrolling
Updated: 7/18/2012
mi
from
Aurora, CO
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Progesterone and Brain Imaging Study
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Nicotine Dependence Clinical Trial
Very Low-Nicotine Cigarettes in Smokers With SUD
Status: Enrolling, Phase II
Updated: 2/16/2016
mi
from
Providence, RI
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Acetylcholine, Tobacco Smoking, Genes and Nicotinic Receptors
Status: Enrolling
Updated: 12/31/1969
mi
from
New Haven, CT
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Smoking Cessation Clinical Trial
Nonsmokers Helping Smokers Quit
Status: Enrolling, Phase III
Updated: 12/3/2014
mi
from
San Diego, CA
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Nicotine Dependence Clinical Trial
Manipulating Tobacco Constituents in Female Menthol Smokers
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Farmington, CT
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
Optimization of Smoking Cessation Strategies Concurrent With Treatment of Tobacco Related Malignancies
Status: Enrolling, Phase II
Updated: 11/28/2017
mi
from
Louisville, KY
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Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases Clinical Trial
HIV+ Alveolar Macrophage Oxidant-mediated Apoptosis of Pulmonary Endothelium
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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Pulmonary / Respiratory Diseases Clinical Trial
Low Dose Aspirin Inhibition of COX-2 Derived PGE2 in Male Smokers
Status: Enrolling, Phase
Updated: 2/19/2013
mi
from
Nashville, TN
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Smoking Cessation Clinical Trial
Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation.
Status: Enrolling, Phase III
Updated: 1/24/2018
mi
from
Belmont, MA
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Nicotine Dependence Clinical Trial
Smoking Cessation Following Psychiatric Hospitalization
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Austin, TX
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Tobacco Use Cessation Clinical Trial
Implementing Tobacco Use Guidelines in Community Health Centers in Vietnam Public Health System
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Tobacco Dependence Clinical Trial
Tobacco Treatment for Employable Californians, Total IMPACT Study
Status: Enrolling
Updated: 4/20/2016
mi
from
San Francisco, CA
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Nicotine Dependence Clinical Trial
rTMS for Smoking Cessation
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Charleston, SC
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases, Other Clinical Trial
Effects of Nicotine Reduction on Smoking Behavior in ADHD Smokers
Status: Enrolling
Updated: 12/31/1969
mi
from
Durham, NC
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Progesterone and Atomoxetine for Cocaine Cessation
Status: Enrolling
Updated: 10/29/2015
mi
from
Minneapolis, MN
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Tobacco Cessation Clinical Trial
Addressing Tobacco Use Disparities in Rural Older Adults Through an Innovative Mobile Phone Intervention
Status: Enrolling
Updated: 1/11/2016
mi
from
Durham, NC
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Smoking Cessation Clinical Trial
Progesterone Augmentation of Nicotine Replacement Therapy Study
Status: Enrolling, Phase IV
Updated: 1/12/2018
mi
from
New Haven, CT
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Smoking Clinical Trial
Maternal Smoking During Pregnancy and Female Fetal Testosterone Levels
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Tobacco Use Disorder Clinical Trial
Optimizing Tobacco Dependence Treatment in the Emergency Department
Status: Enrolling, Phase III
Updated: 2/21/2018
mi
from
New Haven, CT
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Nicotine Dependence Clinical Trial
Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers
Status: Enrolling
Updated: 12/31/1969
mi
from
Durham, NC
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Intermittent Theta Burst for the Treatment of Alcohol Use Disorders in Veterans
Status: Enrolling
Updated: 12/31/1969
mi
from
Stanford, CA
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function
Status: Enrolling, Phase I
Updated: 10/11/2017
mi
from
Los Angeles, CA
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Smoking Cessation Clinical Trial
Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Los Angeles, CA
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Pulmonary / Respiratory Diseases Clinical Trial
Treating Smokeless Tobacco Use in Rural Veterans
Status: Enrolling
Updated: 12/3/2017
mi
from
Iowa City, IA
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Pulmonary / Respiratory Diseases Clinical Trial
A Trial of Directly Observed and Long-term Varenicline
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Bronx, NY
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Nicotine Dependence Clinical Trial
Manipulating Tobacco Constituents in Male Menthol Smokers
Status: Enrolling
Updated: 12/31/1969
mi
from
Farmington, CT
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Smoking Cessation Clinical Trial
Spanish-Language Smoking Cessation Trial
Status: Enrolling
Updated: 12/31/1969
mi
from
Tampa, FL
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Cardiology / Vascular Diseases, Endocrinology, Pulmonary / Respiratory Diseases Clinical Trial
Cardiovascular Risk Screening and Risk Reduction in Women Vets
Status: Enrolling
Updated: 12/31/1969
mi
from
West Los Angeles, CA
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Tobacco Use Disorder Clinical Trial
Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use
Status: Enrolling
Updated: 12/31/1969
mi
from
Minneapolis, MN
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Smoking Cessation Clinical Trial
An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients
Status: Enrolling
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Pulmonary / Respiratory Diseases Clinical Trial
Combining Varenicline and Naltrexone for Smoking Cessation
Status: Enrolling, Phase II
Updated: 3/7/2018
mi
from
Los Angeles, CA
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Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation
Status: Enrolling
Updated: 4/9/2018
mi
from
Boston, MA
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Smoking Cessation Clinical Trial
Take a Break (TAB): mHealth-assisted Skills Building Challenge for Unmotivated Smokers
Status: Enrolling
Updated: 12/31/1969
mi
from
Worcester, MA
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Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases Clinical Trial
RCT of an Internet Cessation Program Plus Online Social Network for HIV+ Smokers
Status: Enrolling
Updated: 4/25/2018
mi
from
Baltimore, MD
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Nicotine Dependence Clinical Trial
The Influence of Electronic (ECIG) Heater Resistance on ECIG Acute Effects
Status: Enrolling
Updated: 12/31/1969
mi
from
Richmond, VA
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Pulmonary / Respiratory Diseases Clinical Trial
AXS-05 Phase II Trial on Smoking Behavior
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Durham, NC
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Tobacco Smoking Clinical Trial
Cognitive and Emotional Skills to Aid Smoking Prevention
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Smoking Cessation Clinical Trial
NRT Sampling and Selection to Increase Medication Adherence
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Birmingham, AL
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Varenicline OTC Trial on Efficacy and Safety
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Phoenix, AZ
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Tobacco Use Clinical Trial
Evaluation of the Abuse Liability of Very Low Nicotine (VLN) Cigarettes
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Overland Park, KS
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Smoking Cessation Clinical Trial
Implementation of Smoking Cessation Within NCI NCORP Community Sites
Status: Enrolling
Updated: 12/31/1969
mi
from
La Crosse, WI
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Smoking Cessation Clinical Trial
Implementation of Smoking Cessation Within NCI NCORP Community Sites
Status: Enrolling
Updated: 12/31/1969
mi
from
Bronx, NY
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Smoking Cessation Clinical Trial
Implementation of Smoking Cessation Within NCI NCORP Community Sites
Status: Enrolling
Updated: 12/31/1969
mi
from
Danville, PA
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Smoking Cessation Clinical Trial
Implementation of Smoking Cessation Within NCI NCORP Community Sites
Status: Enrolling
Updated: 12/31/1969
mi
from
Grand Rapids, MI
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Smoking Cessation Clinical Trial
Implementation of Smoking Cessation Within NCI NCORP Community Sites
Status: Enrolling
Updated: 12/31/1969
mi
from
Greenville, SC
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Smoking Cessation Clinical Trial
Implementation of Smoking Cessation Within NCI NCORP Community Sites
Status: Enrolling
Updated: 12/31/1969
mi
from
Shreveport, LA
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Pulmonary / Respiratory Diseases Clinical Trial
Effects of Metformin During Nicotine Withdrawal
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Pulmonary / Respiratory Diseases Clinical Trial
Sense2Stop:Mobile Sensor Data to Knowledge
Status: Enrolling
Updated: 12/31/1969
mi
from
Chicago, IL
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
Status: Enrolling
Updated: 12/31/1969
mi
from
Providence, RI
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Pulmonary / Respiratory Diseases Clinical Trial
Connecting Alaska Native People to Quit Smoking
Status: Enrolling
Updated: 12/31/1969
mi
from
Rochester, MN
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Tobacco Use Cessation Clinical Trial
Optimizing the Tobacco Cessation Clinical Decision Support Tool.
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Marijuana Smoking Clinical Trial
Behavioral Economic Analysis of Demand for Marijuana
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Providence, RI
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Smoking Cessation Clinical Trial
Tech and Telephone Smoking Cessation Treatment for Young Veterans With PTSD
Status: Enrolling
Updated: 12/31/1969
mi
from
San Francisco, CA
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Madison, WI
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Persistence Targeted Smoking Cessation in Schizophrenia
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
New Brunswick, NJ
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Pulmonary / Respiratory Diseases Clinical Trial
Couples and Smoking
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Los Angeles, CA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
TRIAD Project: Qualitative Study of Adolescent Depression and Smoking
Status: Enrolling
Updated: 5/24/2011
mi
from
Philadelphia, PA
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Nicotine Dependence Clinical Trial
Extinction Based Treatment for Nicotine Dependence
Status: Enrolling
Updated: 4/14/2014
mi
from
Durham, NC
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Endocrinology, Pulmonary / Respiratory Diseases Clinical Trial
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Nicotine Dependence Clinical Trial
Manipulating Tobacco Constituents in Female Menthol Smokers
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Hartford, CT
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Oncology, Pulmonary / Respiratory Diseases, Reproductive Clinical Trial
Smoking Cessation for Cervical Cancer Survivors
Status: Enrolling
Updated: 12/31/1969
mi
from
Oklahoma City, OK
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Pulmonary / Respiratory Diseases Clinical Trial
Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant Women
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Pulmonary / Respiratory Diseases Clinical Trial
Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant Women
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Smoking Cessation Clinical Trial
Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation.
Status: Enrolling, Phase III
Updated: 1/24/2018
mi
from
Austin, TX
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Smoking Cessation Clinical Trial
Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation.
Status: Enrolling, Phase III
Updated: 1/24/2018
mi
from
Gainesville, FL
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Smoking Cessation Clinical Trial
Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation.
Status: Enrolling, Phase III
Updated: 1/24/2018
mi
from
Lincoln, NE
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Smoking Clinical Trial
Tobacco Status Project: Social Media Intervention for Young Adult Smokers
Status: Enrolling
Updated: 5/27/2015
mi
from
San Francisco, CA
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Tobacco Use Disorder Clinical Trial
Project 3, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in People With Current Affective Disorders
Status: Enrolling, Phase I, II
Updated: 4/5/2018
mi
from
Burlington, VT
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Tobacco Dependence Clinical Trial
Tobacco Treatment for Employable Californians, Total IMPACT Study
Status: Enrolling
Updated: 4/20/2016
mi
from
Menlo Park, CA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Status: Enrolling, Phase IV
Updated: 9/12/2017
mi
from
Chicago, IL
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Nicotine Dependence Clinical Trial
Stage Ib Trial of mSMART for Smoking Cessation Medication Adherence
Status: Enrolling
Updated: 4/2/2018
mi
from
Durham, NC
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Pulmonary / Respiratory Diseases Clinical Trial
Control Systems Approach to Predicting Individualized Dynamics of Nicotine Cravings
Status: Enrolling
Updated: 1/6/2016
mi
from
Stony Brook, NY
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Tobacco Use Cessation Clinical Trial
Changing the Default for Tobacco Treatment
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Kansas City, KS
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Pulmonary / Respiratory Diseases Clinical Trial
Behavioral Activation Therapy for Smoking Cessation
Status: Enrolling
Updated: 12/31/1969
mi
from
Houston, TX
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Pulmonary / Respiratory Diseases Clinical Trial
Personalized Intervention Program: Tobacco Treatment for Patients at Risk for Lung Cancer (PIP)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New Haven, CT
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Imaging the Neurochemistry of Drug Addiction With PET
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New Haven, CT
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Pulmonary / Respiratory Diseases Clinical Trial
N-acetylcysteine for Tobacco Use Disorder
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Charleston, SC
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Smoking Clinical Trial
Maternal Smoking During Pregnancy and Female Fetal Testosterone Levels
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Pulmonary / Respiratory Diseases Clinical Trial
Effect of Packaging on Smoking Perceptions and Behavior
Status: Enrolling
Updated: 12/31/1969
mi
from
La Jolla, CA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Music to Reduce Use of Smoking in Patients With Schizophrenia
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Nicotine Dependence Clinical Trial
Stage Ib Trial of mSMART With Varenicline
Status: Enrolling, Phase I
Updated: 2/20/2018
mi
from
Durham, NC
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
Comprehensive Care Program SBRT
Status: Enrolling
Updated: 12/31/1969
mi
from
Royal Oak, MI
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Nicotine Dependence Clinical Trial
YMCA Exercise Intervention for Smoking Cessation Study
Status: Enrolling
Updated: 12/31/1969
mi
from
Austin, TX
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Nicotine Use Disorder Clinical Trial
Real Time fMRI and Quitting Smoking
Status: Enrolling
Updated: 2/9/2018
mi
from
Philadelphia, PA
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
Provider Training in Increasing Patient Tobacco Cessation Counseling and Referrals for Patients With Cancer Undergoing Radiation Therapy
Status: Enrolling
Updated: 10/11/2017
mi
from
Portland, OR
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Musculoskeletal, Pulmonary / Respiratory Diseases Clinical Trial
Pain and Smoking Study
Status: Enrolling
Updated: 12/31/1969
mi
from
Leeds, MA
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Smoking Cessation Clinical Trial
Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Walnut Creek, CA
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Endocrinology, Pulmonary / Respiratory Diseases Clinical Trial
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain (Neuroimaging Supplement)
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
The Lung Screening, Tobacco and Health Project
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Hackensack, NJ
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Smoking Cessation Clinical Trial
Integrating Financial Management Counseling and Smoking Cessation Counseling to Reduce Health and Economic Disparities in Low-Income Immigrants
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
New York, NY
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Neurology, Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Personalized Feedback for Smokers With Elevated Anxiety Sensitivity
Status: Enrolling
Updated: 12/31/1969
mi
from
Houston, TX
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Cigarette Smoking Clinical Trial
Neurobehavioral Substrates of Proranolol's Effects on Drug Cue Reactivity
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Durham, NC
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Cigarette Smoking Clinical Trial
Effects of Smoking Environments on Brain Reactivity
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Durham, NC
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