New Clinical Trials for Pain

Woman suffering from chronic painFrom a simple headache, to a traumatic injury, many medical issues involve a varying degree of pain. Past clinical studies for pain have shown that people have different thresholds for pain. The addictive nature of some current pain medications leaves room for the discovery of an effective pain medication that does not cause dependency. If you are dealing with pain and are interested in participating in a pain clinical trial, please review the list of current trials.

What is Pain?

Pain is a term that refers to an unpleasant feeling in the body. It can originate from many different things and is a helpful tool in diagnosing medical issues in patients. Pain is part of a person’s defense system and should be considered a red flag that something is wrong. Pain is what motivates us to withdraw from the situation, protect what hurts and avoid that situation in the future.

Chronic pain interferes with a person’s life in that it is distracting and can make it difficult to focus. Things like work and socializing can become next to impossible. Pain has also been shown to be psychogenic, meaning that the more painful someone thinks something is, the more painful it will be.

Pain Treatments

There are many over the counter medications for treating pain. Aspirin and ibuprofen are two of the most popular. If something stronger is needed to treat pain doctors can prescribe pain pills or administer medications through an IV. Unfortunately some patients become addicted to these pills. Patients with emotional support have been shown to experience less pain, as in someone going through cancer treatments.

Treating pain is also one of the areas where many people seek alternate treatments. These include acupuncture, hypnosis and spinal manipulation. There is not solid evidence that any of these therapies lead to a patient experiencing less pain.

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We've found
236 Pain
clinical trials

Gastroenterology, Musculoskeletal, Nephrology / Urology, Psychiatry / Psychology, Other Clinical Trial
Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome
Status: Enrolling, Phase IV
Updated: 4/28/2014
mi
from
Philadelphia, PA
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Gastroenterology, Musculoskeletal, Neurology, Rheumatology Clinical Trial
Observational Study of Control Participants for the MAPP Research Network
Status: Enrolling
Updated: 5/14/2013
mi
from
St Louis, MO
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Fibromyalgia Clinical Trial
The Savella Pregnancy Registry
Status: Enrolling, Phase
Updated: 4/1/2018
mi
from
Wilmington, NC
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Jacksonville, FL
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Kissimmee, FL
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Oviedo, FL
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Fibromyalgia Clinical Trial
Cymbalta for Fibromyalgia Pain
Status: Enrolling, Phase IV
Updated: 6/12/2012
mi
from
San Diego, CA
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Neck Pain Clinical Trial
Using fMRI to Determine if Cerebral Hemodynamic Responses to Pain Change Following Thoracic Spine Manipulation in Individuals With Mechanical Neck Pain
Status: Enrolling
Updated: 11/13/2013
mi
from
Peoria, IL
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Neck Pain Clinical Trial
Cardiovascular Response to Two Manual Techniques for Neck Pain
Status: Enrolling
Updated: 1/5/2016
mi
from
Azusa, CA
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Musculoskeletal, Neurology, Orthopedics / Podiatry Clinical Trial
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management
Status: Enrolling
Updated: 5/31/2017
mi
from
Los Angeles, CA
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Musculoskeletal, Neurology, Orthopedics / Podiatry Clinical Trial
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management
Status: Enrolling
Updated: 5/31/2017
mi
from
Mclean, VA
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Complex Regional Pain Syndrome Clinical Trial
Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome
Status: Enrolling
Updated: 12/31/1969
mi
from
Palo Alto, CA
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Neck Pain Clinical Trial
Thrust Manipulation vs. Non-thrust Mobilizations for Mechanical Neck Pain
Status: Enrolling
Updated: 2/11/2016
mi
from
Youngstown, OH
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Franklin, TN
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Loma Linda, CA
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Loma Linda, CA
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Abdominal Pain Clinical Trial
Peppermint Oil Pharmacokinetics/Dynamics and Novel Biological Signatures in Children With Functional Abdominal Pain
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Houston, TX
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Musculoskeletal, Neurology Clinical Trial
Twice Daily Oral ALLOD-2 vs. Placebo in the Treatment of Chronic Low Back Pain (ANODYNE-4)
Status: Enrolling, Phase II, III
Updated: 3/18/2018
mi
from
North Miami, FL
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
Clinical Practice Guidelines for Neck and Low Back Pain in Outpatient Physical Therapy
Status: Enrolling
Updated: 12/31/1969
mi
from
Jacksonville, FL
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Fibromyalgia Clinical Trial
Identification of Potential Biomarkers for Pain
Status: Enrolling, Phase
Updated: 4/4/2018
mi
from
Stratford, NJ
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Musculoskeletal, Neurology, Psychiatry / Psychology, Rheumatology, Orthopedics / Podiatry Clinical Trial
Offset Analgesia as a Measure of Central Sensitization in Children
Status: Enrolling
Updated: 12/31/1969
mi
from
Waltham, MA
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Fibromyalgia Clinical Trial
Isometric Exercise and Endogenous Pain Inhibition
Status: Enrolling
Updated: 12/31/1969
mi
from
Milwaukee, WI
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Complex Regional Pain Syndromes Clinical Trial
Role of the Gut Microbiome in Complex Regional Pain Syndrome
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Saint Louis, MO
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Musculoskeletal, Nephrology / Urology, Psychiatry / Psychology, Other, Reproductive Clinical Trial
Genetic Studies in Interstitial Cystitis (IC)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Altamonte Springs, FL
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Jacksonville, FL
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Orlando, FL
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Abdominal Pain Clinical Trial
Ultrasound Guided Transversus Abdominis Plane (TAP) vs. Trigger Point Injection (TPI) for Abdominal Wall Pain
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Rochester, MN
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Functional Abdominal Pain Clinical Trial
Feeling and Body Investigators
Status: Enrolling
Updated: 12/31/1969
mi
from
Durham, NC
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
The Healing Context in Complementary and Alternative Medicine (CAM): Initial Validation Study
Status: Enrolling
Updated: 11/30/2015
mi
from
Pittsburgh, PA
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Musculoskeletal, Neurology, Orthopedics / Podiatry Clinical Trial
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management
Status: Enrolling
Updated: 5/31/2017
mi
from
Long Beach, CA
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Musculoskeletal, Reproductive Clinical Trial
Transvaginal Pelvic Ultrasound in the ED
Status: Enrolling
Updated: 3/14/2016
mi
from
Minneapolis, MN
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Gastroenterology, Musculoskeletal Clinical Trial
Does Use of Topical Lidocaine in EGD Reduce Amount of IV Midazolam and Fentanyl Required and Shorten Recovery Time
Status: Enrolling
Updated: 12/2/2015
mi
from
Ft. Sam Houston, TX
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Gastroenterology, Musculoskeletal Clinical Trial
Efficacy of Open Label Placebo in Children With FGIDs
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Providence, RI
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Chicago, IL
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Indianapolis, IN
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
San Francisco, CA
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Santa Rosa, CA
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Gastroenterology, Musculoskeletal, Other Clinical Trial
Vitamin D Supplementation in IBS
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion
Status: Enrolling
Updated: 12/31/1969
mi
from
Landover, MD
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure
Status: Enrolling
Updated: 12/31/1969
mi
from
Nashville, TN
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Musculoskeletal, Rheumatology Clinical Trial
Reducing Sedentary Time in Fibromyalgia Patients
Status: Enrolling, Phase
Updated: 3/26/2018
mi
from
Indianapolis, IN
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Neck Pain Clinical Trial
Impact of Practitioner and Instructional Set on Subject Perceptions and Expectations of Cervical Spine Manipulation
Status: Enrolling
Updated: 12/31/1969
mi
from
Las Vegas, NV
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Musculoskeletal Clinical Trial
Overcoming Pain Through Yoga in the Military
Status: Enrolling
Updated: 12/31/1969
mi
from
San Diego, CA
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
Cortisone Shots for Neck Pain
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Palo Alto, CA
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
Cortisone Shots for Neck Pain
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Redwood City, CA
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Musculoskeletal, Neurology, Psychiatry / Psychology, Rheumatology Clinical Trial
Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
New York, NY
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Musculoskeletal, Psychiatry / Psychology, Rheumatology, Orthopedics / Podiatry, Other Clinical Trial
Two Point Discrimination
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Musculoskeletal, Psychiatry / Psychology, Orthopedics / Podiatry Clinical Trial
Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Painful Diabetic Neuropathy Clinical Trial
Quantitative Assessment of Painful Diabetic Peripheral Neuropathy After High Frequency Spinal Cord Stimulation
Status: Enrolling
Updated: 12/31/1969
mi
from
Rochester, MN
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Musculoskeletal, Nephrology / Urology, Psychiatry / Psychology, Reproductive Clinical Trial
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Endocrinology, Gastroenterology, Musculoskeletal, Psychiatry / Psychology Clinical Trial
Brain-Gut Interactions in Overweight and Normal Weight Patients With Chronic Abdominal Pain
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Bethesda, MD
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Fibromyalgia Clinical Trial
Neuroimaging Effects of Cognitive Behavioral Therapy in Fibromyalgia
Status: Enrolling
Updated: 12/31/1969
mi
from
Chestnut Hill, MA
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Orlando, FL
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Endocrinology, Gastroenterology, Musculoskeletal Clinical Trial
Evaluating and Treating Potential Research Participants With Digestive Disorders
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Bethesda, MD
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Musculoskeletal Clinical Trial
New Approaches in Evaluating Patients' Response to Botulinum Toxins in the Treatment of Chronic Neck Pain and Back Pain
Status: Enrolling, Phase I
Updated: 12/5/2017
mi
from
West Haven, CT
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Functional Abdominal Pain Clinical Trial
Feeling and Body Investigators
Status: Enrolling
Updated: 12/31/1969
mi
from
Durham, NC
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Fibromyalgia Clinical Trial
A Brain Imaging Study of Fibromyalgia
Status: Enrolling
Updated: 1/26/2015
mi
from
Charlestown, MA
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Musculoskeletal, Psychiatry / Psychology, Rheumatology, Reproductive Clinical Trial
Injection With OnabotulinumtoxinA (Botox) for the Treatment of Chronic Pelvic Pain
Status: Enrolling, Phase I
Updated: 6/10/2015
mi
from
Mayfield Heights, OH
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Musculoskeletal, Neurology, Orthopedics / Podiatry Clinical Trial
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management
Status: Enrolling
Updated: 5/31/2017
mi
from
Fort Worth, TX
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Appendicitis Clinical Trial
EHR-based Decision Support for Pediatric Acute Abdominal Pain in Emergency Care
Status: Enrolling
Updated: 12/31/1969
mi
from
Minneapolis, MN
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Fort Lauderdale, FL
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Portland, OR
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Chillicothe, OH
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Greenfield, WI
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Kansas City, KS
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Merritt Island, FL
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New Orleans, LA
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Santa Monica, CA
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Musculoskeletal, Neurology, Rheumatology Clinical Trial
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia
Status: Enrolling
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Musculoskeletal, Neurology, Rheumatology Clinical Trial
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia
Status: Enrolling
Updated: 12/31/1969
mi
from
Hartford, CT
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Gastroenterology, Musculoskeletal Clinical Trial
Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis
Status: Enrolling
Updated: 12/31/1969
mi
from
Cleveland, OH
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Musculoskeletal, Psychiatry / Psychology Clinical Trial
Neural Mechanisms of Treatment Response to ADAPT
Status: Enrolling
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
Pain Modulatory Profiles in Massage for Individuals With Neck Pain
Status: Enrolling
Updated: 12/31/1969
mi
from
Gainesville, FL
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Musculoskeletal, Rheumatology Clinical Trial
Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Gainesville, FL
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
PCORI-1609-36568 A Naturalistic Experiment to Evaluate the Impact of Changes to Oregon Medicaid Treatment Reimbursement for Back Pain on Opioid Prescribing and Patient Outcomes
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Portland, OR
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Complex Regional Pain Syndrome Clinical Trial
"Efficacy of Botulinum Toxin Injection in Reducing Limb Pain in Patients With Complex Regional Pain Syndrome"
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
West Haven, CT
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Musculoskeletal, Rheumatology Clinical Trial
Mindfulness to Improve Functional Outcomes in Patients With Fibromyalgia or Central Sensitization
Status: Enrolling
Updated: 12/31/1969
mi
from
Nashville, TN
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Fibromyalgia Clinical Trial
Influence of Exercise Type, Pain Mechanisms, and Biopsychosocial Contributions to Pain Relief in Those With Fibromyalgia
Status: Enrolling
Updated: 12/31/1969
mi
from
Milwaukee, WI
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Musculoskeletal, Neurology, Rheumatology Clinical Trial
Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome
Status: Enrolling, Phase IV
Updated: 4/18/2007
mi
from
Santa Monica, CA
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Gastroenterology, Musculoskeletal, Neurology, Rheumatology Clinical Trial
Observational Study of Control Participants for the MAPP Research Network
Status: Enrolling
Updated: 5/14/2013
mi
from
Seattle, WA
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Gastroenterology, Musculoskeletal, Neurology, Rheumatology Clinical Trial
Observational Study of Control Participants for the MAPP Research Network
Status: Enrolling
Updated: 5/14/2013
mi
from
Ann Arbor, MI
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Gastroenterology, Musculoskeletal, Neurology, Rheumatology Clinical Trial
Observational Study of Control Participants for the MAPP Research Network
Status: Enrolling
Updated: 5/14/2013
mi
from
Stanford, CA
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Fibromyalgia Clinical Trial
Effect of Milnacipran in Patients With Fibromyalgia
Status: Enrolling, Phase II
Updated: 7/24/2013
mi
from
New York, NY
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Fibromyalgia Clinical Trial
Study of Fibromyalgia Treated With Milnacipran
Status: Enrolling, Phase IV
Updated: 6/23/2011
mi
from
Albany, NY
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Neck Pain Clinical Trial
Identify Patients With Neck Pain Likely to Benefit From Education and Exercise
Status: Enrolling
Updated: 6/16/2010
mi
from
Orange Park, FL
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TMS for CRPS - Pilot Study
Status: Enrolling
Updated: 9/11/2013
mi
from
Palo Alto, CA
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Musculoskeletal, Orthopedics / Podiatry Clinical Trial
The Healing Context in Complementary and Alternative Medicine (CAM): Initial Validation Study
Status: Enrolling
Updated: 11/30/2015
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
Musculoskeletal, Psychiatry / Psychology, Rheumatology, Reproductive Clinical Trial
Injection With OnabotulinumtoxinA (Botox) for the Treatment of Chronic Pelvic Pain
Status: Enrolling, Phase I
Updated: 6/10/2015
mi
from
Westlake, OH
Click here to add this to my saved trials
Neck Pain Clinical Trial
The Effects of Thoracic Spine Mobilizations in Individuals With Neck Pain.
Status: Enrolling
Updated: 10/25/2017
mi
from
Pittsburgh, PA
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Bethlehem, PA
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Eugene, OR
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Complex Regional Pain Syndrome (CRPS) Clinical Trial
TARGET Post-Approval Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Musculoskeletal Clinical Trial
RAND Center of Excellence for the Study of Appropriateness of Care in CAM
Status: Enrolling
Updated: 9/26/2017
mi
from
Santa Monica, CA
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Musculoskeletal, Neurology, Oncology Clinical Trial
Lidocaine for Oxaliplatin-induced Neuropathy
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Saint Louis, MO
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Musculoskeletal, Neurology, Rheumatology Clinical Trial
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia
Status: Enrolling
Updated: 12/31/1969
mi
from
Kansas City, MO
Click here to add this to my saved trials
Musculoskeletal, Neurology, Rheumatology Clinical Trial
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia
Status: Enrolling
Updated: 12/31/1969
mi
from
Louisville, KY
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Musculoskeletal, Neurology, Psychiatry / Psychology, Orthopedics / Podiatry Clinical Trial
Pathophysiology of Dystonia and Complex Regional Pain Syndrome
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Bethesda, MD
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