Boston Children's Hospital
300 Longwood Ave
Boston, Massachusetts 02115
(617) 355-6000 http://www.childrenshospital.org

Use our guide to learn which trials are right for you!

Boston Children's Hospital is a 395-bed comprehensive center for pediatric health care. As one of the largest pediatric medical centers in the United States, Children's offers a complete range of health care services for children from birth through 21 years of age. (Our services can begin interventions at 15 weeks gestation and in some situations we also treat adults.)

We have approximately 25,000 inpatient admissions each year and our 200+ specialized clinical programs schedule 557,000 visits annually. Last year the hospital performed more than 26,500 surgical procedures and 158,700 radiological examinations.

Boston Children's Hospital is home to the world's largest research enterprise based at a pediatric hospital. More than 1,100 scientists comprise our research community, including 9 members of the National Academy of Sciences, 11 on-staff members of the Institute of Medicine and 9 members of the Howard Hughes Medical Institute. Current initiatives have attracted a record $225 million in annual funding, including more federal funding than any other pediatric facility.

Through the years, scientists at Boston Children's Hospital have set the pace in pediatric research, identifying treatments and therapies for many debilitating diseases, including those of adulthood.

We've found
143 trials
at this facility
Klinefelter Syndrome Clinical Trial
Klinefelter Fertility Preservation
Status: Enrolling
Updated: 3/20/2013
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Boston, MA
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Gastroenterology, Hematology, Reproductive Clinical Trial
Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita
Status: Enrolling, Phase II
Updated: 9/14/2015
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from
Boston, MA
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Immunology / Infectious Diseases, Neurology, Psychiatry / Psychology, Other Clinical Trial
Genetics of Severe Early Onset Epilepsies
Status: Enrolling
Updated: 2/2/2015
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Boston, MA
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Metabolic Disorders Clinical Trial
A Trial of a Single ProHema-CB Product Transplant in Pediatric Patients With Inherited Metabolic Disorders
Status: Enrolling, Phase I
Updated: 10/23/2015
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Boston, MA
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Endocrinology Clinical Trial
Metabolic Phenotyping in Children With ROHHAD Syndrome
Status: Enrolling
Updated: 11/11/2015
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Boston, MA
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PAH Clinical Trial
Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years
Status: Enrolling, Phase II
Updated: 9/21/2015
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from
Boston, MA
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Hematologic Malignancies Clinical Trial
A Phase 1 Trial of a Single ProHema® CB Product for Pediatric Patients With Hematologic Malignancies
Status: Enrolling, Phase I
Updated: 10/23/2015
mi
from
Boston, MA
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Endocrinology Clinical Trial
Adjusting Insulin Delivery to Activity
Status: Enrolling
Updated: 8/5/2015
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Boston, MA
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Invasive Candidiasis Clinical Trial
BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia
Status: Enrolling
Updated: 11/17/2015
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from
Boston, MA
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Epilepsy Clinical Trial
A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy
Status: Enrolling, Phase II
Updated: 1/13/2016
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Boston, MA
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Rheumatic Joint Disease Clinical Trial
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
Status: Enrolling
Updated: 1/19/2016
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Boston, MA
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Brain Concussion Clinical Trial
LED Therapy for the Treatment of Concussive Brain Injury
Status: Enrolling
Updated: 1/26/2016
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Boston, MA
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Dermatology / Plastic Surgery Clinical Trial
Registry for the Atopic Dermatitis Research Network
Status: Enrolling
Updated: 1/27/2016
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Boston, MA
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Phenylketonuria Clinical Trial
PKU Kuvan Imaging Study
Status: Enrolling
Updated: 2/2/2016
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Boston, MA
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Cystic Fibrosis Clinical Trial
Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients
Status: Enrolling, Phase I, II
Updated: 2/5/2016
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from
Boston, MA
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Neurology, Psychiatry / Psychology Clinical Trial
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
Status: Enrolling
Updated: 2/18/2016
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Boston, MA
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Cystic Fibrosis Clinical Trial
EMPIRE CF: A Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 in Adult CF Patients
Status: Enrolling, Phase II
Updated: 3/10/2016
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Boston, MA
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Myasthenic Syndromes, Congenital Clinical Trial
Amifampridine Phosphate for the Treatment of Pediatric Congenital Myasthenic Syndromes
Status: Enrolling, Phase III
Updated: 3/23/2016
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Boston, MA
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Sickle Cell Anemia Clinical Trial
A Phase II Trial of Regadenoson in Sickle Cell Anemia
Status: Enrolling, Phase II
Updated: 3/24/2016
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Boston, MA
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Spinal Muscular Atrophy Clinical Trial
An Open-Label Study (SHINE) for Patients With Spinal Muscular Atrophy (SMA) Who Participated in Studies With IONIS-SMNRx
Status: Enrolling, Phase III
Updated: 3/28/2016
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Boston, MA
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Seizures Clinical Trial
Pilot Study of Bumetanide for Newborn Seizures
Status: Enrolling, Phase I
Updated: 10/12/2015
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Boston, MA
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Thermoregulation Clinical Trial
Thermoregulation Head Wrap Use for Re-warming of Infants Requiring Cardio-Pulmonary Bypass
Status: Enrolling, Phase I
Updated: 8/29/2012
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Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
Study of the Native Outflow Tract Transcatheter Pulmonary Valve (TPV)
Status: Enrolling
Updated: 3/6/2015
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Boston, MA
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Amblyopia Clinical Trial
Treatment of Residual Amblyopia With Donepezil
Status: Enrolling, Phase I
Updated: 7/31/2015
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Boston, MA
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Duchenne Muscular Dystrophy Clinical Trial
Finding the Optimum Regimen for Duchenne Muscular Dystrophy
Status: Enrolling, Phase III
Updated: 10/22/2015
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Boston, MA
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Short Bowel Syndrome Clinical Trial
A Pharmacokinetic, Safety, and Pharmacodynamic Study of Teduglutide in Pediatric Subjects With Short Bowel Syndrome
Status: Enrolling, Phase III
Updated: 5/16/2014
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Boston, MA
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Hematology Clinical Trial
A Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia
Status: Enrolling, Phase I, II
Updated: 11/19/2015
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Boston, MA
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Asthma Clinical Trial
Environmental Intervention to Reduce Allergens in Urban Schools and Childhood Asthma
Status: Enrolling
Updated: 11/22/2014
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Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
HALO: A Single Arm Prospective Investigation of the SJM™ Masters HP™ 15mm Rotatable Mechanical Heart Valve
Status: Enrolling
Updated: 8/4/2015
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Boston, MA
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Other Clinical Trial
Genomic Sequencing for Childhood Risk and Newborn Illness
Status: Enrolling
Updated: 10/25/2015
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Boston, MA
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Narcolepsy With Cataplexy Clinical Trial
A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy
Status: Enrolling, Phase III
Updated: 11/12/2015
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Boston, MA
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Gastroenterology, Musculoskeletal Clinical Trial
Efficacy of Open Label Placebo in Children With FGIDs
Status: Enrolling
Updated: 3/10/2015
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Boston, MA
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Asthma Clinical Trial
School Inner-City Asthma Intervention Study (SICAS-2)
Status: Enrolling, Phase IV
Updated: 10/14/2015
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Boston, MA
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Intrauterine Growth Restriction Clinical Trial
MRI Assessment of Placental Health
Status: Enrolling
Updated: 12/15/2015
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Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study)
Status: Enrolling
Updated: 7/3/2014
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Boston, MA
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Heart And Lung Failure - Pediatric INsulin Titration Trial
Status: Enrolling, Phase III
Updated: 1/5/2016
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Boston, MA
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Duchenne Muscular Dystrophy Clinical Trial
Deflazacort Expanded Access Program for Children, Adolescents and Adults With Duchenne Muscular Dystrophy
Status: Enrolling
Updated: 2/18/2016
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Boston, MA
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Constipation - Functional Clinical Trial
Efficacy and Safety of Lubiprostone in Pediatric Subjects Aged ≥ 6 Years to < 18 Years With Functional Constipation
Status: Enrolling, Phase III
Updated: 2/29/2016
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Boston, MA
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Pediatric Solid Tumor Clinical Trial
The iCat2, GAIN Consortium Study
Status: Enrolling
Updated: 3/4/2016
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Boston, MA
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Neurology Clinical Trial
A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures
Status: Enrolling, Phase III
Updated: 3/7/2016
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Boston, MA
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Pain Clinical Trial
Multicenter Perioperative Opioid Pharmacogenetic Study
Status: Enrolling
Updated: 3/7/2016
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Boston, MA
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Cystic Fibrosis Clinical Trial
Saline Hypertonic in Preschoolers
Status: Enrolling
Updated: 3/22/2016
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Boston, MA
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Asthma Clinical Trial
Community Empowerment to Pilot a Novel Device for Monitoring Rescue Medication Use in Urban Children With Asthma
Status: Enrolling
Updated: 3/22/2016
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Boston, MA
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Venous Thromboembolism Clinical Trial
Apixaban for the Acute Treatment of Venous Thromboembolism in Children
Status: Enrolling, Phase IV
Updated: 3/30/2016
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Boston, MA
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Hematology Clinical Trial
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia
Status: Enrolling, Phase III
Updated: 3/30/2016
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from
Boston, MA
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Stroke Clinical Trial
Thrombolysis in Pediatric Stroke (TIPS)
Status: Enrolling, Phase I
Updated: 8/29/2013
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Boston, MA
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Pulmonary / Respiratory Diseases Clinical Trial
The Effects of a Standardized Management Plan on Children With Critical Asthma
Status: Enrolling
Updated: 2/5/2013
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Boston, MA
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Postoperative Pain Clinical Trial
Efficacy of an Epidural Versus a Fascia Iliaca Compartment Catheter After Hip Surgery
Status: Enrolling
Updated: 4/17/2013
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Boston, MA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking
Status: Enrolling, Phase I
Updated: 8/14/2015
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Boston, MA
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Clinical Trial
Feasibility Study Evaluating Extraorally Delivered Low Level Light Therapy (LLLT) for the Prevention of Oropharyngeal Mucositis in Pediatric Patients Undergoing Myeloablative Hematopoietic Cell Transplantation
Status: Enrolling
Updated: 4/28/2014
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Boston, MA
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Immune Thrombocytopenia Clinical Trial
ICON1: Treatment Decisions and Outcomes in Pediatric Refractory ITP
Status: Enrolling
Updated: 8/25/2015
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from
Boston, MA
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Asthma Clinical Trial
Asthma (and Dietary) Inflammation Reduction
Status: Enrolling
Updated: 7/27/2015
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Boston, MA
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Craniosynostosis Clinical Trial
The Efficacy and Population Pharmacokinetics of Tranexamic Acid for Craniosynostosis Surgery
Status: Enrolling, Phase IV
Updated: 2/2/2015
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from
Boston, MA
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Langerhans Cell Histiocytosis Clinical Trial
Phase II Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis
Status: Enrolling, Phase II
Updated: 11/19/2015
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Boston, MA
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Effects of High Flow Nasal Cannula on Deadspace Reduction and Regional Distribution of Ventilation
Status: Enrolling
Updated: 6/1/2015
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from
Boston, MA
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Endocrinology, Reproductive Clinical Trial
Continuous Glucose Monitoring and Preterm Infants
Status: Enrolling, Phase IV
Updated: 10/26/2015
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Boston, MA
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Reproductive Clinical Trial
NIRS Monitoring in Premature Infants
Status: Enrolling
Updated: 11/6/2015
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Boston, MA
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Endocrinology Clinical Trial
Efficacy of Continuous Glucose Monitoring in Neonates With Hypoglycemia
Status: Enrolling
Updated: 11/2/2015
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from
Boston, MA
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Oncology, Reproductive Clinical Trial
Lymphatic Anomalies Registry
Status: Enrolling
Updated: 11/4/2015
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Boston, MA
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Males With X-linked Myotubular Myopathy XLMTM Clinical Trial
A Medical Chart Review of Patients With X-Linked Myotubular Myopathy (XLMTM)
Status: Enrolling
Updated: 12/28/2015
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from
Boston, MA
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Pulmonary / Respiratory Diseases, Other Clinical Trial
An Observational Cohort Study of Distribution of Ventilation in Infants and Children Requiring Mechanical Ventilation by Electrical Impedance Tomography
Status: Enrolling
Updated: 8/24/2015
mi
from
Boston, MA
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Hemophilia B Clinical Trial
Safety and Dose Finding Study of DTX101 (AAVrh10FIX) in Adults With Moderate/Severe to Severe Hemophilia B
Status: Enrolling, Phase I, II
Updated: 3/3/2016
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from
Boston, MA
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Generalized Tonic Clonic Seizures Clinical Trial
A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.
Status: Enrolling, Phase III
Updated: 3/7/2016
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from
Boston, MA
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Partial Onset Seizures Clinical Trial
A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects
Status: Enrolling, Phase III
Updated: 3/23/2016
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from
Boston, MA
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Kidney Transplant Clinical Trial
Pharmacokinetics, Safety and Tolerability of Single-dose Belatacept in Adolescent Kidney Transplant Recipients
Status: Enrolling, Phase II
Updated: 3/28/2016
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from
Boston, MA
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Cystic Fibrosis Clinical Trial
Safety, Tolerability, Pharmacokinetics, and Efficacy of JBT-101 in Cystic Fibrosis
Status: Enrolling, Phase II
Updated: 3/31/2016
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from
Boston, MA
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Cystic Fibrosis Clinical Trial
Study of N91115 in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor
Status: Enrolling, Phase II
Updated: 4/1/2016
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from
Boston, MA
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Cystic Fibrosis Clinical Trial
Study of N91115 in Patients With CF Homozygous for the F508del-CFTR Mutation
Status: Enrolling, Phase II
Updated: 4/5/2016
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from
Boston, MA
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Atopic Dermatitis Clinical Trial
A Pediatric Longitudinal Evaluation to Assess the Long-Term Safety of Protopic for the Treatment of Atopic Dermatitis
Status: Enrolling
Updated: 6/28/2012
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from
Boston, MA
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Hematologic Malignancies Clinical Trial
The PUMA Trial is a Trial of a Single ProHema Modulated-CB Unit as Part of a Double CB Transplant in Patients With Hematologic Malignancies.
Status: Enrolling, Phase II
Updated: 10/23/2015
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from
Boston, MA
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Asthma Clinical Trial
The Severe Asthma Research Program III-Boston Clinical Site
Status: Enrolling
Updated: 7/16/2014
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Boston, MA
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Neurology, Orthopedics / Podiatry, Reproductive Clinical Trial
Phase 3 Study of Ataluren in Patients With Nonsense Mutation Duchenne Muscular Dystrophy
Status: Enrolling, Phase III
Updated: 7/21/2014
mi
from
Boston, MA
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Phenylketonuria Clinical Trial
The Brain, Neurological Features and Neuropsychological Functioning in Adults With Phenylketonuria: A Pilot Study
Status: Enrolling
Updated: 1/17/2014
mi
from
Boston, MA
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Respiratory Complications Clinical Trial
The Evaluation of a Noninvasive Respiratory Monitor in Pediatric Patients Undergoing General Anesthesia
Status: Enrolling
Updated: 12/1/2015
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from
Boston, MA
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Other Clinical Trial
The Determination of the Effect of Volatile Anesthetics on Leukocyte Function ex Vivo
Status: Enrolling
Updated: 7/27/2015
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Boston, MA
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Image Evaluation Clinical Trial
Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit
Status: Enrolling
Updated: 9/23/2015
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from
Boston, MA
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Immunology / Infectious Diseases Clinical Trial
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
Status: Enrolling
Updated: 12/14/2015
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Boston, MA
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Surgical Procedures, Operative Clinical Trial
Boston Children's Hospital Post Anesthesia Care Unit Outcomes Study
Status: Enrolling
Updated: 7/11/2014
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Boston, MA
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Growth Disorders Clinical Trial
Comparison of Long-acting Growth Hormone Somavaratan (VRS-317) to Daily Growth Hormone in Pediatric GHD Patients
Status: Enrolling, Phase III
Updated: 1/14/2016
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from
Boston, MA
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Oncology, Orthopedics / Podiatry Clinical Trial
Bone Mineral Density Status in Pediatric and Adolescent Survivors of Childhood Cancer With History of Bone Fracture
Status: Enrolling
Updated: 1/19/2016
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from
Boston, MA
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Nephrology / Urology Clinical Trial
Assessment of Fluoroscopy Times With Surgeon Versus Technologist Control
Status: Enrolling
Updated: 1/26/2016
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Boston, MA
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Brain Concussion Clinical Trial
Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion
Status: Enrolling
Updated: 1/26/2016
mi
from
Boston, MA
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Recurrent Neuroblastoma Clinical Trial
Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma
Status: Enrolling, Phase I
Updated: 2/5/2016
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from
Boston, MA
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Unilateral Cryptorchidism Clinical Trial
Orchidopexy Randomized Clinical Assessment
Status: Enrolling
Updated: 2/7/2016
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Boston, MA
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Neurology, Psychiatry / Psychology, Other Clinical Trial
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
Status: Enrolling
Updated: 2/18/2016
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from
Boston, MA
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Rheumatology Clinical Trial
Start Time Optimization of Biologics in Polyarticular JIA
Status: Enrolling
Updated: 2/18/2016
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Boston, MA
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Venous Insufficiency Clinical Trial
Evaluation of Electrocardiographic Guidance in Accurate Peripherally Inserted Central Catheter Placement in Children.
Status: Enrolling
Updated: 2/24/2016
mi
from
Boston, MA
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Epilepsy, Partial Seizures Clinical Trial
A Study of the Efficacy and Safety of Pregabalin as Add-On Therapy for Partial Onset Seizures in Children Ages 4-16 Years
Status: Enrolling, Phase III
Updated: 3/28/2016
mi
from
Boston, MA
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Peanut Allergy Clinical Trial
Efficacy and Safety of Viaskin Peanut in Children With Immunoglobulin E (IgE)-Mediated Peanut Allergy
Status: Enrolling, Phase III
Updated: 3/31/2016
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from
Boston, MA
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Rett Syndrome Clinical Trial
A Safety Study of NNZ-2566 in Pediatric Rett Syndrome
Status: Enrolling, Phase II
Updated: 4/5/2016
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from
Boston, MA
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Venous Thrombosis Clinical Trial
Evaluation of the Duration of Therapy for Thrombosis in Children
Status: Enrolling, Phase III
Updated: 12/29/2015
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from
Boston, MA
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Hereditary Angioedema Clinical Trial
A Pharmacokinetic, Tolerability and Safety Study of Icatibant in Children and Adolescents With Hereditary Angioedema
Status: Enrolling, Phase III
Updated: 3/12/2015
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from
Boston, MA
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Pediatric Invasive Candidiasis Clinical Trial
PEACE: Pediatric Antifungal Comparative Effectiveness
Status: Enrolling
Updated: 10/27/2015
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from
Boston, MA
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Hematology Clinical Trial
Pyruvate Kinase Deficiency Natural History Study
Status: Enrolling
Updated: 8/30/2015
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from
Boston, MA
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Hemophilia Clinical Trial
ATHN 2: Factor Switching Study
Status: Enrolling
Updated: 11/4/2015
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from
Boston, MA
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Leg Length Discrepancy Clinical Trial
A Randomized Controlled Trial of Leg Length Discrepancy Techniques
Status: Enrolling, Phase
Updated: 7/2/2015
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from
Boston, MA
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Progeria Clinical Trial
Phase I/II Trial of Everolimus in Combination With Lonafarnib in Progeria
Status: Enrolling, Phase I, II
Updated: 12/23/2015
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Boston, MA
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Pyruvate Kinase Deficiency Clinical Trial
A Study of AG-348 in Adult Patients With Pyruvate Kinase Deficiency
Status: Enrolling, Phase II
Updated: 1/11/2016
mi
from
Boston, MA
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
COMMENCE Pulmonary: Clinical Evaluation of Edwards Pericardial Aortic Bioprosthesis (Model 11000A) for Pulmonary Valve Replacement
Status: Enrolling
Updated: 1/12/2016
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from
Boston, MA
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Neurology Clinical Trial
The Effects of Head Trauma on Collegiate Athletes
Status: Enrolling
Updated: 1/26/2016
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from
Boston, MA
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