Boston Children's Hospital
300 Longwood Ave
Boston, Massachusetts 02115
(617) 355-6000 http://www.childrenshospital.org

Use our guide to learn which trials are right for you!

Boston Children's Hospital is a 395-bed comprehensive center for pediatric health care. As one of the largest pediatric medical centers in the United States, Children's offers a complete range of health care services for children from birth through 21 years of age. (Our services can begin interventions at 15 weeks gestation and in some situations we also treat adults.)

We have approximately 25,000 inpatient admissions each year and our 200+ specialized clinical programs schedule 557,000 visits annually. Last year the hospital performed more than 26,500 surgical procedures and 158,700 radiological examinations.

Boston Children's Hospital is home to the world's largest research enterprise based at a pediatric hospital. More than 1,100 scientists comprise our research community, including 9 members of the National Academy of Sciences, 11 on-staff members of the Institute of Medicine and 9 members of the Howard Hughes Medical Institute. Current initiatives have attracted a record $225 million in annual funding, including more federal funding than any other pediatric facility.

Through the years, scientists at Boston Children's Hospital have set the pace in pediatric research, identifying treatments and therapies for many debilitating diseases, including those of adulthood.

We've found
256 trials
at this facility
Hematology, Oncology, Reproductive Clinical Trial
Lymphatic Anomalies Registry
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Langerhans Cell Histiocytosis Clinical Trial
Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related Disorders
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Males With X-linked Myotubular Myopathy (XLMTM) Clinical Trial
A Medical Chart Review of Patients With X-Linked Myotubular Myopathy (XLMTM)
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Multiple Sclerosis Clinical Trial
Adherence in Pediatric Multiple Sclerosis
Status: Enrolling
Updated: 2/5/2015
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from
Boston, MA
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Pulmonary / Respiratory Diseases, Other Clinical Trial
Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography
Status: Enrolling
Updated: 10/25/2017
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from
Boston, MA
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Reproductive Clinical Trial
NIRS Monitoring in Premature Infants
Status: Enrolling, Phase
Updated: 4/25/2018
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from
Boston, MA
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Venous Thromboembolism Clinical Trial
Open Label Study Comparing Efficacy and Safety of Dabigatran Etexilate to Standard of Care in Paediatric Patients With Venous Thromboembolism (VTE)
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Hypertension, Pulmonary Clinical Trial
Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Acute Respiratory Distress Syndrome Clinical Trial
Titration of PEEP During Mechanical Ventilation in Patients With ARDS Using Electrical Impedance Tomography.
Status: Enrolling, Phase II, III
Updated: 10/25/2017
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from
Boston, MA
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Cystic Fibrosis Clinical Trial
Study of N91115 in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor
Status: Enrolling, Phase II
Updated: 7/21/2016
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Boston, MA
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Asthma Clinical Trial
Vitamin D to Prevent Severe Asthma Exacerbations (Vit-D-Kids Asthma)
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Respiratory Complications Clinical Trial
The Evaluation of a Noninvasive Respiratory Monitor in Intubated Infants
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Creatine Deficiency, X-linked Clinical Trial
Observational Study of Males With Creatine Transporter Deficiency
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Pulmonary Arterial Hypertension Clinical Trial
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Heart Defect, Congenital Clinical Trial
Xeltis Bioabsorbable Pulmonary Valved Conduit Early Feasibility Study
Status: Enrolling
Updated: 12/31/1969
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Boston, MA
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases, Reproductive Clinical Trial
COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve Dysfunction
Status: Enrolling
Updated: 10/17/2017
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Boston, MA
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Abdominal Injury Clinical Trial
Contrast-Enhanced Ultrasound in the Evaluation of Abdominal Injuries in Children
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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Boston, MA
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Hemophilia A Clinical Trial
A Gene Transfer Study for Hemophilia A
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
FAST Therapy Trial of Fetal Tachyarrhythmia
Status: Enrolling, Phase III
Updated: 12/14/2017
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from
Boston, MA
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Tuberous Sclerosis Clinical Trial
JASPER Early Intervention for Tuberous Sclerosis
Status: Enrolling
Updated: 12/31/1969
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Boston, MA
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Neurology, Other Clinical Trial
Aerobic Exercise for Concussion
Status: Enrolling
Updated: 12/31/1969
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Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease
Status: Enrolling
Updated: 1/29/2018
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Boston, MA
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Clinical Trial
Child HCAHPS: Automated Day of Discharge Survey
Status: Enrolling
Updated: 4/10/2018
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Boston, MA
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Anesthesia Clinical Trial
Outcomes of an Intraoperative Bispectral Index Monitor
Status: Enrolling, Phase
Updated: 3/9/2018
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Boston, MA
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Validation of a Novel Oxygen Consumption Measurement Technique in Neonates
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Endocrinology, Other Clinical Trial
Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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Boston, MA
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Family Reported Errors and Adverse Events Clinical Trial
Family Engagement in Safety Reporting
Status: Enrolling
Updated: 12/31/1969
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Boston, MA
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Cardiology / Vascular Diseases, Endocrinology Clinical Trial
Dyslipidemia of Obesity Intervention in Teens
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Phenylketonuria (PKU) Clinical Trial
A Non-Interventional Interview Study of Phenylketonuria (PKU) Adults
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Gastroenterology Clinical Trial
A Trial of Thickened Feeds to Treat Gastroesophageal Reflux in Children Admitted After Choking Spell
Status: Enrolling
Updated: 12/31/1969
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from
Boston, MA
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Colitis, Ulcerative Clinical Trial
A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis
Status: Enrolling, Phase III
Updated: 12/31/1969
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Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
Fontan Imaging Biomarkers (FIB) Study
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Clinical Trial
Non-Anesthetized Plexus Technique for Infant (BPBP) MRI Evaluation
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Gastroenterology Clinical Trial
Pediatric Gastroparesis Registry
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Cystic Fibrosis in Children Clinical Trial
Developing e-Health Systems to Improve Growth and Nutrition in CF
Status: Enrolling
Updated: 12/31/1969
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Boston, MA
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Gastroenterology Clinical Trial
Long-term Safety With Vedolizumab Intravenous (IV) in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Status: Enrolling, Phase II
Updated: 12/31/1969
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Boston, MA
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Muscular Dystrophy, Duchenne Clinical Trial
Phase III Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy
Status: Enrolling, Phase III
Updated: 12/31/1969
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Boston, MA
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Gastroenterology Clinical Trial
Flourish™ Pediatric Esophageal Atresia
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Cystic Fibrosis Clinical Trial
Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age
Status: Enrolling, Phase III
Updated: 12/31/1969
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Boston, MA
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Neurology Clinical Trial
Multi-modal Neuroimaging in Children With Cerebral Palsy or Brachial Plexus Birth Palsy
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Urea Cycle Disorders Clinical Trial
Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Down Syndrome, Trisomy 21 Clinical Trial
JASPER Intervention in Down Syndrome
Status: Enrolling
Updated: 12/31/1969
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Boston, MA
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Immune Thrombocytopenia Clinical Trial
Association of Platelet Parameters With Bleeding Severity in Children With ITP
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Phenylketonuria Clinical Trial
The Brain, Neurological Features and Neuropsychological Functioning in Adults With Phenylketonuria: A Pilot Study
Status: Enrolling
Updated: 1/17/2014
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from
Boston, MA
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Autism Clinical Trial
Treatment of Children With Autism Spectrum Disorders and Epileptiform EEG With Divalproex Sodium
Status: Enrolling, Phase II
Updated: 7/25/2016
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from
Boston, MA
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Surgical Procedures, Operative Clinical Trial
Boston Children's Hospital Post Anesthesia Care Unit Outcomes Study
Status: Enrolling
Updated: 7/11/2014
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Boston, MA
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Spinal Muscular Atrophy Clinical Trial
A Study to Assess the Efficacy and Safety of IONIS-SMN Rx in Infants With Spinal Muscular Atrophy
Status: Enrolling, Phase III
Updated: 3/16/2016
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from
Boston, MA
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Unilateral Cryptorchidism Clinical Trial
Orchidopexy Randomized Clinical Assessment
Status: Enrolling
Updated: 12/31/1969
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Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
Status: Enrolling
Updated: 2/9/2018
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Boston, MA
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Immunology / Infectious Diseases Clinical Trial
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
Status: Enrolling, Phase
Updated: 3/28/2018
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Boston, MA
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Other Clinical Trial
The Determination of the Effect of Volatile Anesthetics on Leukocyte Function ex Vivo
Status: Enrolling
Updated: 12/5/2016
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Boston, MA
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Hepatitis C Virus Infection Clinical Trial
A Registry for Adolescent and Pediatric Participants Who Received a Gilead Hepatitis C Virus Direct Acting Antiviral (DAA) in Gilead-Sponsored Chronic Hepatitis C Infection Trials
Status: Enrolling, Phase
Updated: 12/31/1969
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Boston, MA
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Oncology, Orthopedics / Podiatry Clinical Trial
Bone Mineral Density Status in Pediatric and Adolescent Survivors of Childhood Cancer With History of Bone Fracture
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Endocrinology, Oncology, Other Clinical Trial
Effect of Childhood Radioiodine Therapy on Salivary Function
Status: Enrolling
Updated: 2/24/2015
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from
Boston, MA
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Anemia, Sickle Cell Clinical Trial
Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Sleep-Disordered Breathing Clinical Trial
Pediatric Adenotonsillectomy for Snoring
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Nephrology / Urology, Rheumatology Clinical Trial
Pilot Study to Evaluate the Safety and Efficacy of Abatacept in Adults and Children 6 Years and Older With Excessive Loss of Protein in the Urine Due to Either Focal Segmental Glomerulosclerosis (FSGS) or Minimal Change Disease (MCD)
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Neurology, Psychiatry / Psychology Clinical Trial
TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Hemorrhage Clinical Trial
Reversal Dabigatran Anticoagulant Effect With Idarucizumab
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Autism Spectrum Disorder Clinical Trial
A Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Participants With Autism Spectrum Disorder (ASD)
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Tuberous Sclerosis Complex Clinical Trial
Preventing Epilepsy Using Vigabatrin In Infants With Tuberous Sclerosis Complex
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Thrombosis Clinical Trial
A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Clinical Trial
RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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from
Boston, MA
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Renal Disease Clinical Trial
Biokinetics Study for Tc-99m MAG3 in Pediatric Molecular Imaging
Status: Enrolling, Phase IV
Updated: 12/31/1969
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from
Boston, MA
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Hematopoietic Stem Cell Transplantation Clinical Trial
Safety and Tolerability of Intravenous Fish Oil Lipid Emulsion in Children Undergoing Hematopoietic Cell Transplantation
Status: Enrolling, Phase I
Updated: 12/31/1969
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from
Boston, MA
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Post-Traumatic Headaches Clinical Trial
A Prospective Controlled Treatment Trial for Post-Traumatic Headaches
Status: Enrolling, Phase III
Updated: 2/21/2018
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from
Boston, MA
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Endocrinology Clinical Trial
Study of ARQ 092 in Patients With PIK3CA-related Overgrowth Spectrum and Proteus Syndrome
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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from
Boston, MA
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Sickle Cell Disease Clinical Trial
Gene Transfer for Sickle Cell Disease
Status: Enrolling, Phase I
Updated: 12/31/1969
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from
Boston, MA
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Pulmonary / Respiratory Diseases, Other Clinical Trial
Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis
Status: Enrolling, Phase I
Updated: 12/31/1969
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from
Boston, MA
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Spinal Muscular Atrophy Clinical Trial
Study of Intrathecal Administration of AVXS-101 for Spinal Muscular Atrophy
Status: Enrolling, Phase I
Updated: 12/31/1969
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from
Boston, MA
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Low-grade Glioma Clinical Trial
TAK-580 In Gliomas and Other Tumors
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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from
Boston, MA
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Pulmonary / Respiratory Diseases, Other Clinical Trial
Study Assessing the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interactions of PTI-801 in Healthy Volunteers, and Safety, Tolerability, and Pharmacokinetics of PTI-801 in Subjects With Cystic Fibrosis
Status: Enrolling, Phase I
Updated: 12/31/1969
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from
Boston, MA
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Cardiology / Vascular Diseases Clinical Trial
Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
Status: Enrolling
Updated: 3/21/2018
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from
Boston, MA
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Other Clinical Trial
Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Cystic Fibrosis Clinical Trial
A Study to Evaluate the Safety of Long-term Ivacaftor Treatment in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age at Treatment Initiation and Have an Approved Ivacaftor-Responsive Mutation
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Exostoses, Multiple Hereditary Clinical Trial
An Efficacy and Safety Study of Palovarotene for the Treatment of MO
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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New Daily Persistent Headache (NDPH) Clinical Trial
Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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from
Boston, MA
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Hypoxic-Ischemic Encephalopathy Clinical Trial
Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk
Status: Enrolling
Updated: 1/24/2018
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from
Boston, MA
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Peanut Allergy Clinical Trial
Evaluating the Safety and Efficacy of Fecal Microbiota Transplant in Peanut Allergic Patients
Status: Enrolling, Phase I
Updated: 12/31/1969
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from
Boston, MA
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Cardiology / Vascular Diseases, Hematology, Immunology / Infectious Diseases, Nephrology / Urology Clinical Trial
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Prader-Willi Syndrome Clinical Trial
A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Clinical Trial
Expanded Access Program to Provide Treatment With Pitolisant to Adult Patients in the U.S. With Excessive Daytime Sleepiness Associated With Narcolepsy With or Without Cataplexy
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Fragile X Syndrome Clinical Trial
AFQ056 for Language Learning in Children With FXS
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Drug Effect Clinical Trial
Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Dermatology / Plastic Surgery, Immunology / Infectious Diseases, Neurology, Oncology, Reproductive Clinical Trial
Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Neurology, Psychiatry / Psychology Clinical Trial
Boston Outcomes of Autism in Toddlers Study
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Mental Fatigue Clinical Trial
A Tele-mental Health Intervention to Support Parents Caring for a Technology-dependent Child at Home
Status: Enrolling
Updated: 12/31/1969
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from
Boston, MA
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Cystic Fibrosis Clinical Trial
Study Assessing PTI-428 Safety, Tolerability, Pharmacokinetics and Effect in Subjects With Cystic Fibrosis
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Cardiology / Vascular Diseases, Gastroenterology, Immunology / Infectious Diseases, Other Clinical Trial
Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease
Status: Enrolling
Updated: 12/31/1969
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from
Boston, MA
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Fragile X Syndrome Clinical Trial
Clinical Study Of caNNabidiol in childrEn and adolesCenTs With Fragile X (CONNECT-FX)
Status: Enrolling, Phase II, III
Updated: 12/31/1969
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from
Boston, MA
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Cystic Fibrosis Clinical Trial
Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Subjects 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Succinic Semialdehyde Dehydrogenase Deficiency Clinical Trial
Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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Acute Lymphoblastic Leukemia ALL Clinical Trial
Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL
Status: Enrolling, Phase I
Updated: 12/31/1969
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from
Boston, MA
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Achondroplasia Clinical Trial
Observational Study Investigating Clinical & Anthropometric Characteristics of Children With Achondroplasia.
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Boston, MA
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HIV/AIDS Clinical Trial
PlusCare: Mobile Platform to Increase Linkage to Care in Adolescents Living With HIV/AIDS
Status: Enrolling
Updated: 12/31/1969
mi
from
Boston, MA
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Cytomegalovirus Infections Clinical Trial
Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Boston, MA
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Neurology, Other Clinical Trial
A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
Status: Enrolling, Phase III
Updated: 12/31/1969
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from
Boston, MA
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Venous Thrombosis Clinical Trial
Evaluation of the Duration of Therapy for Thrombosis in Children
Status: Enrolling, Phase III
Updated: 3/18/2018
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from
Boston, MA
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Immunology / Infectious Diseases, Oncology Clinical Trial
Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY)
Status: Enrolling, Phase III
Updated: 3/14/2016
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from
Boston, MA
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Oncology Clinical Trial
iCAT for Recurrent/Refractory/HR Solid Tumors
Status: Enrolling
Updated: 5/10/2013
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Boston, MA
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