The Determination of the Effect of Volatile Anesthetics on Leukocyte Function ex Vivo



Status:Recruiting
Conditions:Hospital
Therapuetic Areas:Other
Healthy:No
Age Range:Any
Updated:12/7/2016
Start Date:November 2014
Contact:Rachel Bernier, MPH
Email:Rachel.Bernier@childrens.harvard.edu
Phone:857-218-5348

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One of the most common side effects of a surgical procedure is infection. In order to lower
the number of infections that occur after surgery, it is important for physicians to know
how medications used during surgery affect the way the body fights infection. Often, when
anesthesiologists are helping people go to sleep before surgery they give people medications
known as "volatile anesthetics". Volatile anesthetics are medications that can change from a
liquid or solid to a gas very easily. Some studies suggest that these types of medications
may change the way white blood cells work in the body. Changing the way white blood cells
work could possibly increase the person's risk of infection after their surgery or weaken
their body's ability to fight infections. The goal of this research study is to learn about
how volatile anesthesia medications change the way white blood cells work in people having
anesthesia for cardiac procedures. To do this, investigators will examine the function of
while blood cells in the laboratory based setting.


Inclusion Criteria:

- Male and female patients

- greater than or equal to 12 months of age

- scheduled for a cardiac catheterization, cardiac surgery, or cardiac MRI

Exclusion Criteria:

- known underlying hematological disorder

- known oncological disorder

- patients who do not require preoperative laboratory testing
We found this trial at
1
site
300 Longwood Ave
Boston, Massachusetts 02115
(617) 355-6000
Principal Investigator: Koichi Yuki, M.D.
Phone: 857-218-5348
Boston Children's Hospital Boston Children's Hospital is a 395-bed comprehensive center for pediatric health care....
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