Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

Conditions:Chronic Pain, Orthopedic, Psychiatric, Pain
Therapuetic Areas:Musculoskeletal, Psychiatry / Psychology, Orthopedics / Podiatry
Age Range:18 - 65
Start Date:June 2015
End Date:June 2019
Contact:Aaron Yue, MD
Phone:(650) 497-0485

Use our guide to learn which trials are right for you!

The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of
complex regional pain syndrome (CRPS). Study participants will be randomly assigned to
receive either LDN or placebo for a period of several weeks. During this period participants
will be asked to come to several visits, which will include sensory testing, physical
assessments, and questionnaires.

Inclusion Criteria:

- Upper and/or lower extremity CRPS

- On stable treatment for 3 months

- CRPS for at least 1 year

- Meet the Budapest criteria for CRPS at time of the study.

Exclusion Criteria:

- Any known allergy to naltrexone or naloxone

- Use of prescription opioid analgesics or illegal opioid use

- Current of planned pregnancy.
We found this trial at
Palo Alto, California 94304
Principal Investigator: Sean Mackey, MD, PhD
Phone: 650-497-0485
Palo Alto, CA
Click here to add this to my saved trials