Duke Univ Med Ctr
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111 http://www.dukehealth.org/

Use our guide to learn which trials are right for you!

As a world-class academic and health care system, Duke Medicine strives to transform medicine and health locally and globally through innovative scientific research, rapid translation of breakthrough discoveries, educating future clinical and scientific leaders, advocating and practicing evidence-based medicine to improve community health, and leading efforts to eliminate health inequalities.

Duke Medicine conceptually integrates the Duke University Health System, the Duke University School of Medicine, and the Duke University School of Nursing.

We've found
625 trials
at this facility
Bacteremia Clinical Trial
Virulence Determinants in S Aureus Bacteremia
Status: Enrolling
Updated: 10/25/2015
mi
from
Durham, NC
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Oncology Clinical Trial
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma
Status: Enrolling, Phase III
Updated: 9/3/2014
mi
from
Durham, NC
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Glioblastoma Multiforme Clinical Trial
AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme
Status: Enrolling, Phase I, II
Updated: 5/29/2007
mi
from
Durham, NC
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Tibial Fractures Clinical Trial
A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures
Status: Enrolling
Updated: 11/16/2015
mi
from
Durham, NC
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Lung Cancer Clinical Trial
Comparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung Cancer
Status: Enrolling, Phase III
Updated: 8/28/2015
mi
from
Durham, NC
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Other Clinical Trial
Genetics of Spina Bifida and Anencephaly
Status: Enrolling
Updated: 8/26/2015
mi
from
Durham, NC
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Advanced Cancer Clinical Trial
Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies
Status: Enrolling, Phase I
Updated: 10/28/2015
mi
from
Durham, NC
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Other, Reproductive Clinical Trial
Thymus Transplantation Safety-Efficacy
Status: Enrolling, Phase I, II
Updated: 12/10/2015
mi
from
Durham, NC
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Cystic Fibrosis Clinical Trial
I Change Adherence & Raise Expectations
Status: Enrolling
Updated: 11/27/2012
mi
from
Durham, NC
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Oncology Clinical Trial
Biomarker Trial of Everolimus in Patients With Advanced Renal Cell Carcinoma
Status: Enrolling
Updated: 4/13/2011
mi
from
Durham, NC
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Adenovirus Disease Clinical Trial
The Adv Halt Trial
Status: Enrolling
Updated: 11/14/2012
mi
from
Durham, NC
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Oncology Clinical Trial
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
Status: Enrolling
Updated: 11/12/2015
mi
from
Durham, NC
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Cervical Cancer Clinical Trial
Cervical Cancer Detection Using Optical Spectroscopy
Status: Enrolling
Updated: 7/13/2015
mi
from
Durham, NC
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Breast Cancer Clinical Trial
Bevacizumab, Metronomic Chemotherapy (CM), Diet and Exercise After Preoperative Chemotherapy for Breast Cancer
Status: Enrolling
Updated: 3/14/2013
mi
from
Durham, NC
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Cognitive Decline Clinical Trial
Lidocaine For Neuroprotection During Cardiac Surgery
Status: Enrolling
Updated: 8/4/2015
mi
from
Durham, NC
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Diffuse Large B-Cell Lymphoma Clinical Trial
Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Status: Enrolling, Phase II
Updated: 2/11/2015
mi
from
Durham, NC
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Oncology Clinical Trial
Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: Enrolling
Updated: 11/7/2012
mi
from
Durham, NC
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Psychiatry / Psychology Clinical Trial
Family Treatment for Adolescents With Anorexia Nervosa
Status: Enrolling, Phase I
Updated: 1/19/2011
mi
from
Durham, NC
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Psychiatry / Psychology Clinical Trial
Acceptance-Based Separated Family Treatment for Adolescent Anorexia Nervosa
Status: Enrolling
Updated: 1/10/2011
mi
from
Durham, NC
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Hematology, Oncology Clinical Trial
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
Status: Enrolling
Updated: 11/12/2015
mi
from
Durham, NC
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Hepatitis B Clinical Trial
Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir Versus Tenofovir Monotherapy in Chronic Hepatitis B
Status: Enrolling
Updated: 10/28/2015
mi
from
Durham, NC
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Hepatitis C Virus Clinical Trial
Study With PegInterferon Alfa-2a, Ribavirin and BMS-790052 With or Without BMS-650032 for Participants in Some Hepatitis C Virus (HCV) Trials
Status: Enrolling, Phase II
Updated: 12/2/2013
mi
from
Durham, NC
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Breast Cancer Clinical Trial
Letrozole in Treating Postmenopausal Women With Ductal Carcinoma in Situ
Status: Enrolling, Phase II
Updated: 9/18/2015
mi
from
Durham, NC
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Hematology, Oncology Clinical Trial
Study of Vosaroxin or Placebo in Combination With Cytarabine in Patients With First Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: Enrolling
Updated: 7/3/2013
mi
from
Durham, NC
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Smoking Clinical Trial
Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction
Status: Enrolling
Updated: 2/4/2010
mi
from
Durham, NC
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Breast Cancer Clinical Trial
Trastuzumab in Treating Older Women With Early-Stage Breast Cancer
Status: Enrolling, Phase II
Updated: 6/26/2014
mi
from
Durham, NC
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Breast Cancer Clinical Trial
HKI-272 for HER2-Positive Breast Cancer and Brain Metastases
Status: Enrolling, Phase II
Updated: 11/12/2015
mi
from
Durham, NC
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Acute Kidney Injury Clinical Trial
A Study to Evaluate the Safety and Efficacy of AC607 for the Treatment of Kidney Injury in Cardiac Surgery Subjects
Status: Enrolling, Phase II
Updated: 2/19/2014
mi
from
Durham, NC
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Severe Aortic Stenosis Clinical Trial
Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Very High Risk Subjects Who Need Aortic Valve Replacement
Status: Enrolling
Updated: 10/26/2015
mi
from
Durham, NC
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Childhood Leukemia Clinical Trial
Symptom Clusters in Children With Leukemia
Status: Enrolling
Updated: 3/31/2014
mi
from
Durham, NC
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Immunology / Infectious Diseases Clinical Trial
Pharmacokinetics, Safety, and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in Adolescents
Status: Enrolling, Phase II, III
Updated: 10/18/2014
mi
from
Durham, NC
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Prostate Cancer Clinical Trial
Carbohydrate Restriction and Prostate Cancer Growth
Status: Enrolling
Updated: 10/20/2015
mi
from
Durham, NC
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Prostate Cancer Clinical Trial
Abiraterone Race in Metastatic Castrate-resistant Prostate Cancer
Status: Enrolling, Phase II
Updated: 11/25/2015
mi
from
Durham, NC
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Chronic Heart Failure Clinical Trial
A Clinical Trial to Evaluate the HeartWare® Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)
Status: Enrolling
Updated: 5/28/2015
mi
from
Durham, NC
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Immune Thrombocytopenia Clinical Trial
ICON1: Treatment Decisions and Outcomes in Pediatric Refractory ITP
Status: Enrolling
Updated: 8/25/2015
mi
from
Durham, NC
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Pulmonary / Respiratory Diseases, Reproductive Clinical Trial
BABY STEPS II: SMS Scheduled Gradual Reduction Text Messages to Help Pregnant Smokers Quit
Status: Enrolling
Updated: 8/3/2015
mi
from
Durham, NC
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Parkinson Disease Clinical Trial
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Status: Enrolling
Updated: 5/4/2015
mi
from
Durham, NC
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Ophthalmology Clinical Trial
Imaging Lens Deposits in Exfoliation Syndrome
Status: Enrolling
Updated: 3/5/2015
mi
from
Durham, NC
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Malignant Neoplasms Brain Clinical Trial
Basiliximab in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Undergoing Targeted Immunotherapy and Temozolomide-Caused Lymphopenia
Status: Enrolling, Phase I
Updated: 5/21/2015
mi
from
Durham, NC
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Melanoma Clinical Trial
A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic Melanoma
Status: Enrolling, Phase I
Updated: 5/6/2014
mi
from
Durham, NC
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Oncology Clinical Trial
Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer
Status: Enrolling, Phase III
Updated: 9/18/2015
mi
from
Durham, NC
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Osteosarcoma Clinical Trial
Monocyte Phenotypic and Functional Differences
Status: Enrolling
Updated: 8/5/2015
mi
from
Durham, NC
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Recurrent Neuroblastoma Clinical Trial
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Monoclonal Antibody Ch14.18 in Treating Younger Patients With Refractory or Relapsed Neuroblastoma
Status: Enrolling, Phase II
Updated: 3/12/2015
mi
from
Durham, NC
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Cardiology / Vascular Diseases, Endocrinology, Pulmonary / Respiratory Diseases Clinical Trial
Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
Status: Enrolling, Phase II
Updated: 7/21/2015
mi
from
Durham, NC
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Asthma Clinical Trial
Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients With Asthma (CPAP)
Status: Enrolling, Phase II
Updated: 8/1/2013
mi
from
Durham, NC
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Healthy Volunteer Clinical Trial
Caloric Stimulation on Cerebral Blood Flow
Status: Enrolling
Updated: 2/12/2015
mi
from
Durham, NC
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Oncology Clinical Trial
DC Migration Study for Newly-Diagnosed GBM
Status: Enrolling, Phase II
Updated: 10/2/2015
mi
from
Durham, NC
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Reproductive Clinical Trial
Testosterone and Cortisol Levels in Infants
Status: Enrolling
Updated: 11/5/2015
mi
from
Durham, NC
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Healthy Volunteers Clinical Trial
Intra-Arterial Microdosing: Proof-of-Concept in Humans
Status: Enrolling, Phase
Updated: 8/5/2015
mi
from
Durham, NC
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Colorectal Carcinoma Clinical Trial
Phase 1 Study of MGD007 in Relapsed/Refractory Metastatic Colorectal Carcinoma
Status: Enrolling, Phase I
Updated: 9/22/2015
mi
from
Durham, NC
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Chronic Heart Failure Clinical Trial
Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure
Status: Enrolling, Phase III
Updated: 12/30/2015
mi
from
Durham, NC
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Hematology Clinical Trial
A Safety Study of Carfilzomib in Patients With Previously-Treated Systemic Light Chain Amyloidosis
Status: Enrolling, Phase I
Updated: 1/4/2016
mi
from
Durham, NC
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Gastroenterology, Oncology Clinical Trial
Photodynamic Therapy (PDT) Oncology Registry
Status: Enrolling
Updated: 1/7/2016
mi
from
Durham, NC
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Leukemia Clinical Trial
A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia
Status: Enrolling, Phase II
Updated: 1/13/2016
mi
from
Durham, NC
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Hematological Malignancies Clinical Trial
Naive T-Cell Depleted DLI Following Allo Stem Cell Transplant
Status: Enrolling, Phase I
Updated: 1/14/2016
mi
from
Durham, NC
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Rheumatology Clinical Trial
Verifying the Effectiveness of the NUsurface® System
Status: Enrolling
Updated: 1/14/2016
mi
from
Durham, NC
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Hematology Clinical Trial
Apixaban in Patients With Sickle Cell Disease
Status: Enrolling, Phase III
Updated: 1/18/2016
mi
from
Durham, NC
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Gastroenterology Clinical Trial
Impact of Oral Antibiotic Treatment on C. Difficile
Status: Enrolling, Phase IV
Updated: 1/19/2016
mi
from
Durham, NC
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High Risk Melanoma Clinical Trial
A Pilot Study of Ipilumimab and Radiation in Poor Prognosis Melanoma
Status: Enrolling, Phase I
Updated: 1/20/2016
mi
from
Durham, NC
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Cardiology / Vascular Diseases Clinical Trial
Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve
Status: Enrolling
Updated: 1/21/2016
mi
from
Durham, NC
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Atrial Fibrillation Clinical Trial
Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery
Status: Enrolling, Phase I, II
Updated: 1/25/2016
mi
from
Durham, NC
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Radiation Injury Clinical Trial
Longitudinal MR Imaging of Pulmonary Function in Patients Receiving Thoracic Radiation Treatment
Status: Enrolling, Phase I
Updated: 2/2/2016
mi
from
Durham, NC
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Prostate Cancer Clinical Trial
3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy
Status: Enrolling, Phase II
Updated: 2/11/2016
mi
from
Durham, NC
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Leukemia, Myeloid, Chronic Clinical Trial
The Life After Stopping Tyrosine Kinase Inhibitors Study (The LAST Study)
Status: Enrolling, Phase II
Updated: 2/12/2016
mi
from
Durham, NC
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Hematology, Oncology Clinical Trial
Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM
Status: Enrolling, Phase I, II
Updated: 2/15/2016
mi
from
Durham, NC
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Dermatology / Plastic Surgery, Immunology / Infectious Diseases Clinical Trial
Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections
Status: Enrolling, Phase III
Updated: 2/21/2016
mi
from
Durham, NC
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Muscular Dystrophies Clinical Trial
A Study of the Safety, Tolerability & Efficacy of Long-term Administration of Drisapersen in US & Canadian Subjects
Status: Enrolling, Phase III
Updated: 2/26/2016
mi
from
Durham, NC
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Metastatic Breast Cancer Clinical Trial
Aerobic Training in Metastatic Breast Cancer
Status: Enrolling
Updated: 3/2/2016
mi
from
Durham, NC
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Hematology, Oncology Clinical Trial
Ipilimumab and Rituximab in Treating Patients With Relapsed or Refractory B-cell Lymphoma
Status: Enrolling, Phase I
Updated: 3/3/2016
mi
from
Durham, NC
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Duchenne Muscular Dystrophy Clinical Trial
A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Duchenne Muscular Dystrophy
Status: Enrolling, Phase II
Updated: 3/7/2016
mi
from
Durham, NC
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Hypertrophic Cardiomyopathy Clinical Trial
HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy
Status: Enrolling
Updated: 3/11/2016
mi
from
Durham, NC
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Oncology Clinical Trial
Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction Cancer
Status: Enrolling, Phase I, II
Updated: 3/11/2016
mi
from
Durham, NC
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Vestibular Function in Cochlear Implant Patients Clinical Trial
Vestibular Function After Cochlear Implantation Using Soft Surgery Techniques
Status: Enrolling
Updated: 3/15/2016
mi
from
Durham, NC
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Oncology Clinical Trial
Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery
Status: Enrolling, Phase III
Updated: 3/17/2016
mi
from
Durham, NC
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Pulmonary Arterial Hypertension Clinical Trial
Beraprost-314d Added-on to Tyvaso® (BEAT)
Status: Enrolling, Phase III
Updated: 3/17/2016
mi
from
Durham, NC
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Oncology Clinical Trial
Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma
Status: Enrolling, Phase III
Updated: 3/18/2016
mi
from
Durham, NC
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Malignant Neoplasm Clinical Trial
Collection and Storage of Tissue and Blood Samples From Patients With Cancer
Status: Enrolling
Updated: 3/22/2016
mi
from
Durham, NC
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Non-Small Cell Lung Cancer Clinical Trial
Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC
Status: Enrolling, Phase III
Updated: 3/22/2016
mi
from
Durham, NC
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Anemia, Sickle Cell Clinical Trial
Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
Status: Enrolling, Phase III
Updated: 3/23/2016
mi
from
Durham, NC
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Narcolepsy Clinical Trial
"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Narcolepsy"
Status: Enrolling, Phase III
Updated: 3/26/2016
mi
from
Durham, NC
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Oncology Clinical Trial
A Study of Nivolumab and Nivolumab Plus Ipilimumab in Recurrent and Metastatic Colon Cancer (CheckMate 142)
Status: Enrolling, Phase I, II
Updated: 3/28/2016
mi
from
Durham, NC
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Advanced Cancer Clinical Trial
A Phase I/IIa Study of BMS-986148 in Subjects With Select Advanced Solid Tumors
Status: Enrolling, Phase I, II
Updated: 3/28/2016
mi
from
Durham, NC
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Hematology, Oncology, Reproductive Clinical Trial
Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes
Status: Enrolling, Phase II
Updated: 3/30/2016
mi
from
Durham, NC
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Immunology / Infectious Diseases Clinical Trial
Oral SCY-078 vs Standard-of-Care Following IV Echinocandin in the Treatment of Invasive Candidiasis
Status: Enrolling, Phase II
Updated: 4/1/2016
mi
from
Durham, NC
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Oncology Clinical Trial
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
Status: Enrolling, Phase III
Updated: 4/5/2016
mi
from
Durham, NC
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Oncology, Other Clinical Trial
Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia
Status: Enrolling, Phase III
Updated: 4/5/2016
mi
from
Durham, NC
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Small Cell Lung Cancer Clinical Trial
Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer (TRINITY)
Status: Enrolling, Phase II
Updated: 4/5/2016
mi
from
Durham, NC
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Oncology Clinical Trial
Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine, With or Without Bevacizumab, as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II, Stage III, Stage IV, or Recurrent Stage I Epithelial Ovarian Cancer or Fallopian Tube Cancer
Status: Enrolling, Phase III
Updated: 12/6/2013
mi
from
Durham, NC
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Lymphoma Clinical Trial
Response-Based Therapy Assessed By PET Scan in Treating Patients With Bulky Stage I and Stage II Classical Hodgkin Lymphoma
Status: Enrolling, Phase II
Updated: 8/25/2015
mi
from
Durham, NC
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Colorectal Cancer Clinical Trial
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
Status: Enrolling, Phase III
Updated: 9/3/2015
mi
from
Durham, NC
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Oncology Clinical Trial
Ixabepilone in Treating Patients With Recurrent or Persistent Uterine Cancer
Status: Enrolling, Phase II
Updated: 9/4/2013
mi
from
Durham, NC
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Oncology Clinical Trial
Stereotactic Radiosurgery in Treating Patients With Brain Metastases
Status: Enrolling
Updated: 9/8/2011
mi
from
Durham, NC
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Recurrent Childhood Medulloblastoma Clinical Trial
GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment
Status: Enrolling
Updated: 1/3/2013
mi
from
Durham, NC
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Hematology, Oncology Clinical Trial
Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)
Status: Enrolling, Phase III
Updated: 6/4/2015
mi
from
Durham, NC
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Glioblastoma Multiforme Clinical Trial
Single-Arm Open-Label Multicenter Study of VB-111 in Patients With Recurrent Glioblastoma Multiforme
Status: Enrolling, Phase I, II
Updated: 4/27/2015
mi
from
Durham, NC
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Arthroplasty, Replacement, Knee Clinical Trial
Triathlon Total Stabilizer (TS) Outcomes Study
Status: Enrolling
Updated: 3/10/2014
mi
from
Durham, NC
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Oncology Clinical Trial
Gemcitabine Hydrochloride and Docetaxel With or Without Bevacizumab in Treating Patients With Advanced or Recurrent Uterine Leiomyosarcoma
Status: Enrolling, Phase III
Updated: 12/6/2013
mi
from
Durham, NC
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Breast Cancer Clinical Trial
An Optical Assay System for Intra Operative Assessment of Tumor Margins in Patients
Status: Enrolling
Updated: 9/10/2015
mi
from
Durham, NC
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Oncology Clinical Trial
Combination Chemotherapy With or Without Lestaurtinib in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: Enrolling, Phase III
Updated: 2/5/2014
mi
from
Durham, NC
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Cardiology / Vascular Diseases, Neurology Clinical Trial
Carotid Stenting vs. Surgery of Severe Carotid Artery Disease and Stroke Prevention in Asymptomatic Patients (ACT I)
Status: Enrolling
Updated: 8/30/2012
mi
from
Durham, NC
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