Respiratory Muscle Training in L-Onset Pompe Disease (LOPD)
| Status: | Recruiting |
|---|---|
| Conditions: | Endocrine, Diabetes |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/31/2019 |
| Start Date: | February 2, 2017 |
| End Date: | June 2019 |
| Contact: | Amy Walker |
| Email: | amy.walker1@duke.edu |
| Phone: | 919-684-1732 |
Respiratory Muscle Training in Late-Onset Pompe Disease
This study is being done to test the effects of respiratory muscle training (RMT) in patients
with late-onset Pompe Disease (LOPD) who have weakness of their breathing muscles. The
results of this study will help design future research studies about RMT in LOPD. The goals
of this study are to decide if sham-RMT is a useful control condition for RMT and to choose
the best ways to measure the health benefits of RMT in LOPD.
with late-onset Pompe Disease (LOPD) who have weakness of their breathing muscles. The
results of this study will help design future research studies about RMT in LOPD. The goals
of this study are to decide if sham-RMT is a useful control condition for RMT and to choose
the best ways to measure the health benefits of RMT in LOPD.
Inclusion Criteria:
- Age ≥ 18 years
- Diagnosis of LOPD
- On enzyme replacement therapy for ≥ 26 weeks at pretest
- Able to follow directions for study participation
- Able to complete a home-based RMT regimen
Exclusion Criteria:
- Neurodegenerative conditions (e.g. stroke, dementia) or other serious neurologic
condition that would prevent meaningful study participation as determined at the
discretion of the principle investigator
- Inability to give legally effective consent
- Inability to read and understand English
We found this trial at
1
site
2301 Erwin Rd
Durham, North Carolina 27710
Durham, North Carolina 27710
919-684-8111
Principal Investigator: Harrision Jones
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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