Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer



Status:Completed
Conditions:Cancer, Blood Cancer, Hematology, Leukemia
Therapuetic Areas:Hematology, Oncology
Healthy:No
Age Range:Any - 30
Updated:7/21/2018
Start Date:October 13, 2003
End Date:June 30, 2018

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A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors

This study is collecting and storing malignant, borderline malignant neoplasms, and related
biological samples from young patients with cancer. Collecting and storing samples of tumor
tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help
the study of cancer in the future.

OBJECTIVES:

I. Collect malignant, borderline malignant neoplasms, and related biological specimens from
Children's Oncology Group institutions for cases in which there is no disease-specific
biologic protocol.

II. Provide a repository for long-term storage of malignant, borderline malignant neoplasms,
and related biological specimens from these patients.

III. Make specimens available to qualified researchers to understand the biology of cancer in
these patients.

OUTLINE:

Tumor tissue samples, blood, and bone marrow aspirates are collected and stored for future
analysis.

Inclusion Criteria:

- Meets any of the following criteria:

- Diagnosed with primary neoplasm

- Developed a second malignant neoplasm

- Any diagnoses having an ICD-O Morphology Code ending in 1, 2, or 3 as listed in
the International Classification of Disease for Oncology, Third Edition

- Must have biological specimens including solid tumors and leukemias available

- Solid tumors meeting the following criteria:

- Snap frozen primary tumor OR OCT embedded primary tumor OR formalin fixed
(block or tissue in formalin) primary tumor AND at least 10 unstained
paraffin slides for NIH Mandated QC (tumors that have undergone central
pathology review are allowed)

- Slides for pathology review (instead of slides for QC) are required for
patients with rare tumors

- Pleural fluid or cytologic specimens meeting the following criteria:

- At least 1 mL of fluid and at least 2 unstained cytospin slides (or 2
unstained smears)

- Slides for pathology review (instead of slides for QC) are required for
patients with rare tumors

- ALL/AML

- 3-6 mL of bone marrow aspirate and 10 mL of whole blood

- Not eligible for disease-specific biology or banking protocol
We found this trial at
176
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121 Dekalb Ave
Brooklyn, New York 11205
(718) 250-8000
Brooklyn Hospital Center Welcome to The Brooklyn Hospital Center, dedicated to Keeping Brooklyn healthy and...
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1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
(505) 272-4946
Principal Investigator: Koh B. Boayue
Phone: 505-272-6972
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
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4900 Mueller Boulevard
Austin, Texas 78723
(512) 324-0000
Principal Investigator: Sharon K. Lockhart
Phone: 512-324-8022
Dell Children's Medical Center of Central Texas Welcome to Dell Children
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2545 Schoenersville Rd
Bethlehem, Pennsylvania 18017
(484) 884-2200
Principal Investigator: Philip M. Monteleone
Phone: 484-884-2201
Lehigh Valley Hospital - Muhlenberg At Lehigh Valley Health Network, we continually go the extra...
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1600 7th Avenue
Birmingham, Alabama 35233
(205) 638-9100
Principal Investigator: Alyssa T. Reddy
Phone: 205-934-0309
Children's Hospital of Alabama Children
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666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Principal Investigator: Martin L. Brecher
Phone: 877-275-7724
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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1 South Prospect Street
Burlington, Vermont 05401
802-656-8990
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3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
 1-513-636-4200 
Cincinnati Children's Hospital Medical Center Patients and families from across the region and around the...
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11100 Euclid Avenue
Cleveland, Ohio 44106
(216) 844-1000
Principal Investigator: Yousif (Joe) H. Matloub
Phone: 216-844-5437
Rainbow Babies and Children's Hospital UH Rainbow Babies & Children’s Hospital is a 244-bed, full-service...
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700 Childrens Drive
Columbus, Ohio 43205
(616) 722-2000
Principal Investigator: Laura T. Martin
Phone: 614-722-2708
Nationwide Children's Hospital At Nationwide Children’s, we are creating the future of pediatric health care....
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3533 South Alameda Street
Corpus Christi, Texas 78411
(361) 694-5000
Principal Investigator: M. C. Johnson
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7777 Forest Ln # C840
Dallas, Texas 75230
(972) 566-7000
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Medical City Dallas Hospital If you have concerns for your health, that of a family...
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1200 Pleasant Street
Des Moines, Iowa 50309
(515) 241-KIDS
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Phone: 515-241-6729
Blank Children's Hospital Blank Children's Hospital is completely dedicated to meeting the unique health care...
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1500 E Duarte Rd
Duarte, California 91010
(626) 256-4673
City of Hope Comprehensive Cancer Center City of Hope is a leading research and treatment...
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3300 Gallows Road
Falls Church, Virginia 22042
(703) 776-4001
Principal Investigator: Marshall A. Schorin
Phone: 703-208-6650
Inova Fairfax Hospital Inova Fairfax Hospital, Inova's flagship hospital, is an 833-bed, nationally recognized regional...
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1 Hurley Plaza
Flint, Michigan 48503
(810) 262-9000
Principal Investigator: Susumu Inoue
Phone: 888-606-6556
Hurley Medical Center From its founding in 1908, Hurley Medical Center has devoted itself to...
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9981 S Healthpark Dr # 465
Fort Myers, Florida 33908
239-343-5000
Lee Memorial Health System Our origins can be traced to the Fall of 1916 when...
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3551 Roger Brooke Dr
Fort Sam Houston, Texas 78234
(210) 916-4141
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100 Michigan Street Northeast
Grand Rapids, Michigan 49503
616.391.9000
Principal Investigator: David S. Dickens
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282 Washington St
Hartford, Connecticut 06106
(860) 545-9000
Principal Investigator: Michael S. Isakoff
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Connecticut Children's Medical Center Connecticut Children’s Medical Center is a nationally recognized, 187-bed not-for-profit children’s...
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2500 N State St
Jackson, Mississippi 39216
(601) 984-1000
Principal Investigator: Gail C. Megason
Phone: 601-815-6700
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524 South Park Street
Kalamazoo, Michigan 49007
(269) 341-7654
Principal Investigator: Jeffrey S. Lobel
Phone: 800-227-2345
Bronson Methodist Hospital Our healthcare system serves patients and families throughout southwest Michigan and northern...
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2401 Gillham Rd
Kansas City, Missouri 64108
(816) 234-3000
Principal Investigator: Maxine L. Hetherington
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Children's Mercy Hospital Children's Mercy Hospitals and Clinics continues redefining pediatric medicine throughout the Midwest...
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529 West Markham Street
Little Rock, Arkansas 72205
(501) 686-7000
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8700 Beverly Blvd # 8211
Los Angeles, California 90048
(1-800-233-2771)
Principal Investigator: Fataneh (Fae) Majlessipour
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4650 Sunset Blvd
Los Angeles, California 90027
 (323) 660-2450
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4015 22nd Place
Lubbock, Texas 79410
806-725-0000
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9300 Valley Children's Pl
Madera, California 93720
(559) 353-3000
Principal Investigator: Vonda L. Crouse
Phone: 866-353-5437
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601 Children's Lane
Norfolk, Virginia 23507
(757) 668-7000
Principal Investigator: Eric J. Lowe
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Children's Hospital of The King's Daughters Children
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747 52nd St
Oakland, California 94609
(510) 428-3000
Principal Investigator: Carla B. Golden
Phone: 510-450-7600
Children's Hospital and Research Center Oakland For nearly 100 years, Children's Hospital & Research Center...
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1201 W La Veta Ave
Orange, California 92868
(714) 997-3000
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1717 South Orange Avenue # 100
Orlando, Florida 32806
(407) 650-7000
Nemours Children's Clinic - Orlando Located near downtown Orlando, Nemours Children’s Clinic, Orlando is a...
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5153 North 9th Avenue
Pensacola, Florida 32504
(850) 505-4700
Principal Investigator: Jeffrey H. Schwartz
Phone: 904-697-3529
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530 Northeast Glen Oak Avenue
Peoria, Illinois 61603
(309) 624-4945
Principal Investigator: Pedro A. De Alarcon
Phone: 309-655-3258
Saint Jude Midwest Affiliate The Jim and Trudy Maloof St. Jude Midwest Affiliate Clinic was...
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South 34th Street
Philadelphia, Pennsylvania 19104
 215-590-1000
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4401 Penn Avenue
Pittsburgh, Pennsylvania 15224
412-692-5325
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Phone: 412-692-5573
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
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Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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60 Crittenden Blvd # 70
Rochester, New York 14642
(585) 275-2121
Principal Investigator: Lisa R. Hackney
Phone: 585-275-5830
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7700 Floyd Curl Dr
San Antonio, Texas 78229
(210) 575-7000
Principal Investigator: Jaime Estrada
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Methodist Children's Hospital of South Texas Methodist Children
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4502 Medical Drive
San Antonio, Texas 78284
(210) 567-7000
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3020 Childrens way
San Diego, California 92123
(858) 576-1700
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1 Tampa General Cir
Tampa, Florida 33606
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40 Sunshine Cottage Road
Valhalla, New York 10595
(914) 594-4000
New York Medical College The College was founded in 1860 by a group of New...
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1600 Rockland Road
Wilmington, Delaware 19803
(302) 651-4200
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Alfred I. duPont Hospital for Children Nemours began more than 70 years ago with the...
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Akron, Ohio 44308
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Albany, New York 12208
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1540 East Hospital Drive
Ann Arbor, Michigan 48109
(877) 475-6688
Principal Investigator: Raymond J. Hutchinson
Phone: 800-865-1125
C S Mott Children's Hospital Behind the doors of C.S. Mott Children's Hospital there exist...
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Asheville, North Carolina 28801
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Atlanta, Georgia 30322
Principal Investigator: Howard M. Katzenstein
Phone: 800-811-8480
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13123 E 16th Ave
Aurora, Colorado 80045
(720) 777-1234
Principal Investigator: Douglas K. Graham
Phone: 720-777-6672
Children's Hospital Colorado At Children's Hospital Colorado, we see more, treat more and heal more...
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2401 W Belvedere Ave
Baltimore, Maryland 21215
(410) 601-9000
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Sinai Hospital of Baltimore Sinai Hospital of Baltimore provides a broad array of high-quality, cost-effective...
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8901 Rockville Pike
Bethesda, Maryland 20889
(301) 295-4000
Principal Investigator: Stephen S. Roberts
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Walter Reed National Military Medical Center The Walter Reed National Military Medical Center is one...
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100 E Idaho St
Boise, Idaho 83712
(208) 381-2711
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Phone: 617-636-5000
Saint Luke's Mountain States Tumor Institute For more than 100 years, St. Luke
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Principal Investigator: Carlos Rodriguez-Galindo
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Brooklyn, New York 11219
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Chapel Hill, North Carolina 27599
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Principal Investigator: Jacqueline M. Kraveka
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Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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3110 MacCorkle Avenue Southeast
Charleston, West Virginia 25304
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Charlotte, North Carolina 28204
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Charlotte, North Carolina 28204
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Chattanooga, Tennessee 37403
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Chicago, Illinois 60614
Principal Investigator: David O. Walterhouse
Phone: 773-880-4562
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1200 West Harrison Stree
Chicago, Illinois 60607
(312) 996-4350
Principal Investigator: Mary L. Schmidt
Phone: 312-355-3046
Univ of Illinois A major research university in the heart of one of the world's...
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5841 S Maryland Ave
Chicago, Illinois 60637
1-773-702-6180
University of Chicago Comprehensive Cancer Center The University of Chicago Comprehensive Cancer Center (UCCCC) is...
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2049 E 100th St
Cleveland, Ohio 44106
(216) 444-2200
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Cleveland Clinic Foundation The Cleveland Clinic (formally known as The Cleveland Clinic Foundation) is a...
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Columbia, Missouri 65201
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Phone: 573-882-7440
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5 Richland Medical Park Dr
Columbia, South Carolina 29203
(803) 434-7000
Principal Investigator: Ronnie W. Neuberg
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Palmetto Health Richland Palmetto Health Richland, originally founded in 1892 as Columbia Hospital, has a...
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100 North Academy Avenue
Danville, Pennsylvania 17822
570-271-6211
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Geisinger Medical Center Since 1915, Geisinger Medical Center has been known as the region’s resource...
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Dayton, Ohio 45404
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Denver, Colorado 80218
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4160 John R St #2122
Detroit, Michigan 48201
(313) 833-1785
Principal Investigator: Zhihong J. Wang
Phone: 313-576-9363
Wayne State University/Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
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22101 Moross Rd
Detroit, Michigan 48236
(313) 343-4000
Principal Investigator: Hadi Sawaf
Phone: 313-343-3166
Saint John Hospital and Medical Center Founded in 1952, St. John Hospital and Medical Center...
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9333 Imperial Highway
Downey, California 90242
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2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Principal Investigator: Susan G. Kreissman
Phone: 888-275-3853
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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East Lansing, Michigan 48824
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801 Broadway North
Fargo, North Dakota 58122
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1600 S Andrews Ave
Fort Lauderdale, Florida 33316
(954) 355-4400
Principal Investigator: Hector M. Rodriguez-Cortes
Phone: 954-355-5346
Broward Health Medical Center Broward Health, providing service for more than 75 years, is a...
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Fort Myers, Florida 33908
Principal Investigator: Emad K. Salman
Phone: 239-343-5333
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801 7th Avenue
Fort Worth, Texas 76104
(682) 885-4000
Principal Investigator: Mary Meaghan P. Granger
Phone: 682-885-2103
Cook Children's Medical Center Cook Children's Health Care System is a not-for-profit, nationally recognized pediatric...
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1600 Southwest Archer Road
Gainesville, Florida 32610
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835 S Van Buren St
Green Bay, Wisconsin 54301
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900 West Faris Rd.
Greenville, South Carolina 29605
(864)455-8898
Principal Investigator: Nichole L. Bryant
Phone: 864-241-6251
BI-LO Charities Children's Cancer Center The BI-LO Charities Children
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Greenville, South Carolina 29605
Principal Investigator: Cary E. Stroud
Phone: 864-241-6251
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30 Prospect Ave
Hackensack, New Jersey 07601
(201) 996-2000
Principal Investigator: Burton E. Appel
Phone: 201-996-2879
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Hershey, Pennsylvania 17033
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Honolulu, Hawaii 96813
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1319 Punahou St
Honolulu, Hawaii 96826
(808) 983-6000
Kapiolani Medical Center for Women and Children Hawai‘i Pacific Health is an integrated health care...
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705 Riley Hospital Dr
Indianapolis, Indiana 46202
(317) 944-5000
Principal Investigator: Robert J. Fallon
Phone: 317-274-2552
Riley Hospital for Children Riley Hospital for Children at IU Health is a place of...
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Indianapolis, Indiana 46260
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Jacksonville, Florida 32207
Principal Investigator: Eric S. Sandler
Phone: 904-697-3529
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Johnson City, Tennessee 37614
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Kalamazoo, Michigan 49008
Principal Investigator: Jeffrey S. Lobel
Phone: 800-227-2345
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Kansas City, Kansas 66160
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2018 W Clinch Ave
Knoxville, Tennessee 37916
(865) 541-8000
Principal Investigator: Ray C. Pais
Phone: 865-541-8266
East Tennessee Children's Hospital East Tennessee Children's Hospital is a not-for-profit, private, independent pediatric medical...
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Las Vegas, Nevada 89109
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