Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer



Status:Completed
Conditions:Cancer, Blood Cancer, Hematology, Leukemia
Therapuetic Areas:Hematology, Oncology
Healthy:No
Age Range:Any - 30
Updated:7/21/2018
Start Date:October 13, 2003
End Date:June 30, 2018

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A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors

This study is collecting and storing malignant, borderline malignant neoplasms, and related
biological samples from young patients with cancer. Collecting and storing samples of tumor
tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help
the study of cancer in the future.

OBJECTIVES:

I. Collect malignant, borderline malignant neoplasms, and related biological specimens from
Children's Oncology Group institutions for cases in which there is no disease-specific
biologic protocol.

II. Provide a repository for long-term storage of malignant, borderline malignant neoplasms,
and related biological specimens from these patients.

III. Make specimens available to qualified researchers to understand the biology of cancer in
these patients.

OUTLINE:

Tumor tissue samples, blood, and bone marrow aspirates are collected and stored for future
analysis.

Inclusion Criteria:

- Meets any of the following criteria:

- Diagnosed with primary neoplasm

- Developed a second malignant neoplasm

- Any diagnoses having an ICD-O Morphology Code ending in 1, 2, or 3 as listed in
the International Classification of Disease for Oncology, Third Edition

- Must have biological specimens including solid tumors and leukemias available

- Solid tumors meeting the following criteria:

- Snap frozen primary tumor OR OCT embedded primary tumor OR formalin fixed
(block or tissue in formalin) primary tumor AND at least 10 unstained
paraffin slides for NIH Mandated QC (tumors that have undergone central
pathology review are allowed)

- Slides for pathology review (instead of slides for QC) are required for
patients with rare tumors

- Pleural fluid or cytologic specimens meeting the following criteria:

- At least 1 mL of fluid and at least 2 unstained cytospin slides (or 2
unstained smears)

- Slides for pathology review (instead of slides for QC) are required for
patients with rare tumors

- ALL/AML

- 3-6 mL of bone marrow aspirate and 10 mL of whole blood

- Not eligible for disease-specific biology or banking protocol
We found this trial at
176
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East Lansing, Michigan 48824
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1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
(505) 272-4946
Principal Investigator: Koh B. Boayue
Phone: 505-272-6972
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
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4900 Mueller Boulevard
Austin, Texas 78723
(512) 324-0000
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Phone: 512-324-8022
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2545 Schoenersville Rd
Bethlehem, Pennsylvania 18017
(484) 884-2200
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Phone: 484-884-2201
Lehigh Valley Hospital - Muhlenberg At Lehigh Valley Health Network, we continually go the extra...
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1600 7th Avenue
Birmingham, Alabama 35233
(205) 638-9100
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Phone: 205-934-0309
Children's Hospital of Alabama Children
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666 Elm Street
Buffalo, New York 14263
(716) 845-2300
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Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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1 South Prospect Street
Burlington, Vermont 05401
802-656-8990
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3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
 1-513-636-4200 
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11100 Euclid Avenue
Cleveland, Ohio 44106
(216) 844-1000
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Rainbow Babies and Children's Hospital UH Rainbow Babies & Children’s Hospital is a 244-bed, full-service...
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700 Childrens Drive
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3533 South Alameda Street
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282 Washington St
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2500 N State St
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2401 Gillham Rd
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8700 Beverly Blvd # 8211
Los Angeles, California 90048
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4015 22nd Place
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747 52nd St
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5153 North 9th Avenue
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530 Northeast Glen Oak Avenue
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3181 Southwest Sam Jackson Park Road
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60 Crittenden Blvd # 70
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7700 Floyd Curl Dr
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4502 Medical Drive
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3020 Childrens way
San Diego, California 92123
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1600 Rockland Road
Wilmington, Delaware 19803
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13123 E 16th Ave
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171 Ashley Avenue
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1200 West Harrison Stree
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2049 E 100th St
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5 Richland Medical Park Dr
Columbia, South Carolina 29203
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4160 John R St #2122
Detroit, Michigan 48201
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22101 Moross Rd
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2301 Erwin Rd
Durham, North Carolina 27710
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801 Broadway North
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1600 S Andrews Ave
Fort Lauderdale, Florida 33316
(954) 355-4400
Principal Investigator: Hector M. Rodriguez-Cortes
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801 7th Avenue
Fort Worth, Texas 76104
(682) 885-4000
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Cook Children's Medical Center Cook Children's Health Care System is a not-for-profit, nationally recognized pediatric...
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1600 Southwest Archer Road
Gainesville, Florida 32610
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Green Bay, Wisconsin 54301
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900 West Faris Rd.
Greenville, South Carolina 29605
(864)455-8898
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Phone: 864-241-6251
BI-LO Charities Children's Cancer Center The BI-LO Charities Children
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Greenville, South Carolina 29605
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30 Prospect Ave
Hackensack, New Jersey 07601
(201) 996-2000
Principal Investigator: Burton E. Appel
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Honolulu, Hawaii 96826
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705 Riley Hospital Dr
Indianapolis, Indiana 46202
(317) 944-5000
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Indianapolis, Indiana 46260
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Jacksonville, Florida 32207
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Kansas City, Kansas 66160
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2018 W Clinch Ave
Knoxville, Tennessee 37916
(865) 541-8000
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East Tennessee Children's Hospital East Tennessee Children's Hospital is a not-for-profit, private, independent pediatric medical...
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Las Vegas, Nevada 89109
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