Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical Trial



Status:Recruiting
Conditions:Blood Cancer, Lymphoma, Leukemia
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:4/2/2016
Start Date:July 2004

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Ancillary Laboratory Protocol For the Collection of Diagnostic Material On Patients Considered For ECOG Treatment Trials For Leukemia Or Related Hematologic Disorders

RATIONALE: Collecting and storing samples of blood and bone marrow from patients with cancer
to study in the laboratory may help doctors learn more about diagnosing cancer and determine
a patient's eligibility for a treatment clinical trial. It may also help the study of cancer
in the future.

PURPOSE: This laboratory study is collecting tissue samples from patients with leukemia or
other blood disorders who are planning to enroll in an ECOG leukemia treatment clinical
trial.

OBJECTIVES:

- To provide a mechanism for sample collection and submission for diagnostic review to
determine eligibility of patients with suspected leukemia or related hematologic
disorders for enrollment on ECOG leukemia clinical trials.

- To obtain baseline samples for correlative studies outlined in parent clinical trials.

OUTLINE: This is a cohort, multicenter study.

Patients submit bone marrow and/or blood samples. The samples are studied to determine
patients' eligibility for ECOG leukemia treatment clinical trials. Samples may be stored for
future correlative studies related to ECOG treatment clinical trials.

DISEASE CHARACTERISTICS:

- Candidate for enrollment on an ECOG treatment clinical trial for acute or chronic
leukemia

- Suspected clinical diagnosis and protocol ID number of the treatment clinical
trial under consideration must be submitted to ECOG's Leukemia Translational
Studies Laboratory to ensure that the required antibody panels are used and
functional assays are performed

- Chosen ECOG treatment clinical trial must be active and accruing

- Patient must not have begun treatment on the ECOG treatment clinical trial

- Patient may be concurrently enrolled on this laboratory study and a treatment
clinical trial if immediate treatment is medically necessary

- If subsequent diagnostic review alters the original diagnosis, the patient will
be removed from the treatment clinical trial

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics
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