Avera Cancer Institute
3900 W Avera Drive
Sioux Falls, South Dakota 57108
(605) 322-4700 http://www.avera.org/cancer-institute/

Use our guide to learn which trials are right for you!

Avera, the health ministry of the Benedictine and Presentation Sisters, is a regional partnership of health professionals who share support services to maintain excellent care at more than 300 locations in eastern South Dakota and surrounding states.

Our caregivers are supported by the resources and expertise of the region's largest health system. Management and other support services are provided through the Avera Central Office in Sioux Falls, S. D., and its five regional centers: Avera St. Luke's in Aberdeen, S.D.; Avera Queen of Peace in Mitchell, S.D.; Avera McKennan in Sioux Falls, S.D.; Avera Sacred Heart in Yankton, S.D.; and Avera Marshall in Marshall, Minn.

We've found
58 trials
at this facility
Esophageal Cancer Clinical Trial
Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer
Status: Enrolling, Phase II
Updated: 3/15/2011
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Radiation Therapy With or Without Cisplatin in Treating Patients With Recurrent Endometrial Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Dermatology / Plastic Surgery, Hematology, Immunology / Infectious Diseases, Oncology, Reproductive Clinical Trial
CA-IX, p16, Proliferative Markers, and HPV in Diagnosing Cervical Lesions in Patients With Abnormal Cervical Cells
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Endocrinology, Gastroenterology, Hematology, Oncology, Reproductive Clinical Trial
Integrated Cancer Repository for Cancer Research
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Endocrinology, Hematology, Oncology Clinical Trial
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Pembrolizumab in Treating Patients With Triple-Negative Breast Cancer
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Ovarian and Breast
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Clinical Trial
Pembrolizumab in Treating Patients With Locally Advanced Bladder Cancer
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Non Small Cell Lung Cancer Clinical Trial
Study of AM0010 With Nivolumab Compared to Nivolumab Alone Second-line Tx in Patients With Metastatic Non-Small Cell Lung Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Pembrolizumab and Epacadostat in Treating Patients With Recurrent, Persistent, or Progressive Ovarian Clear Cell Carcinoma
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Ovarian Cancer Clinical Trial
A Phase 3 Comparison of Platinum-Based Therapy With TSR-042 and Niraparib Versus Standard of Care Platinum-Based Therapy as First-Line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology, Reproductive Clinical Trial
Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer
Status: Enrolling
Updated: 3/7/2014
mi
from
Sioux Falls, SD
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Lymphoma, Non-Hodgkin Clinical Trial
Lenalidomide Plus Rituximab Followed by Lenalidomide Versus Rituximab Maintenance for Relapsed/Refractory Follicular, Marginal Zone or Mantle Cell Lymphoma.
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Cancer Clinical Trial
Study of Molecular Profile-Related Evidence to Determine Individualized Therapy for Advanced or Poor Prognosis Cancers
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Multiple Myeloma Clinical Trial
An Effectiveness and Safety Study of Ixazomib in Combination With Lenalidomide and Dexamethasone (IRD) in Participants With Multiple Myeloma (MM) Previously Receiving a Bortezomib-based Induction Regimen (US MM-6)
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Non Small Cell Lung Cancer Clinical Trial
Study of AM0010 With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Patients With Metastatic Non-Small Cell Lung Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Solid Tumors Clinical Trial
Tomivosertib (eFT-508) in Combination With PD-1/PD-L1 Inhibitor Therapy
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Neuroblastoma Clinical Trial
Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma
Status: Enrolling
Updated: 4/5/2011
mi
from
Sioux Falls, SD
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Oncology, Reproductive Clinical Trial
Radiation Therapy With or Without Chemotherapy in Patients With Stage I-IIA Cervical Cancer Who Previously Underwent Surgery
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Breast Neoplasms Clinical Trial
Neratinib +/- Fulvestrant in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Breast Cancer Clinical Trial
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Plasma Cell Myeloma Clinical Trial
Bortezomib or Carfilzomib With Lenalidomide and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery
Status: Enrolling, Phase III
Updated: 5/4/2017
mi
from
Sioux Falls, SD
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Fatigue Clinical Trial
Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Genetic Testing in Screening Patients With Stage IB-IIIA Non-Small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Erlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Multiple Myeloma Clinical Trial
Expanded Access Treatment Protocol CA204-143
Status: Enrolling
Updated: 9/11/2015
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Breast Carcinoma Clinical Trial
Breast Cancer WEight Loss Study (BWEL Study)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Treatment Naive Follicular Lymphoma Clinical Trial
Study of Ibrutinib and Rituximab in Treatment Naïve Follicular Lymphoma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Early Breast Cancer Clinical Trial
Talazoparib For Neoadjuvant Treatment Of Germline Brca1/2 Mutation Patients With Early Triple-negative Breast Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Hematology, Oncology Clinical Trial
An Efficacy and Safety Trial of Fedratinib in Subjects With DIPSS, Intermediate or High-Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Neurology, Oncology, Psychiatry / Psychology Clinical Trial
Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer
Status: Enrolling
Updated: 11/9/2012
mi
from
Sioux Falls, SD
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Cancer Clinical Trial
Collecting Tumor Samples From Patients With Gynecological Tumors
Status: Enrolling
Updated: 8/30/2012
mi
from
Sioux Falls, SD
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Sarcoma Clinical Trial
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma
Status: Enrolling, Phase III
Updated: 6/23/2014
mi
from
Sioux Falls, SD
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Acute Oral Mucositis Pain Clinical Trial
Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy
Status: Enrolling, Phase III
Updated: 8/4/2015
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Advanced Solid Tumor Clinical Trial
Evaluation of the Safety and Tolerability of TAK-228 With TAK-117 and Paclitaxel in Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Durvalumab and Tremelimumab in Treating Patients With Recurrent Stage IV Lung Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical Trial
Status: Enrolling
Updated: 12/5/2012
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Colorectal Neoplasms Clinical Trial
S0820, Adenoma and Second Primary Prevention Trial
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Breast Cancer Clinical Trial
Node Negative, Invasive Breast Cancer Single Fraction IOERT
Status: Enrolling
Updated: 6/17/2015
mi
from
Sioux Falls, SD
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Solid Tumors Habouring NTRK Fusion Clinical Trial
A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Renal Cell Carcinoma Clinical Trial
Safety and Efficacy Study of Pembrolizumab (MK-3475) as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post Nephrectomy (MK-3475-564/KEYNOTE-564)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Diffuse Large B-Cell Lymphoma Clinical Trial
Study to Assess Enzastaurin + R-CHOP in Subjects With DLBCL With the Genomic Biomarker DGM1™
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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Oncology Clinical Trial
Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Sioux Falls, SD
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