Neuropsychological and Behavioral Testing in Younger Patients With Cancer



Status:Recruiting
Conditions:Cancer, Cancer, Cognitive Studies, Other Indications, Brain Cancer, Neurology, Psychiatric
Therapuetic Areas:Neurology, Oncology, Psychiatry / Psychology, Other
Healthy:No
Age Range:Any - 21
Updated:2/24/2019
Start Date:September 15, 2008

Use our guide to learn which trials are right for you!

Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children With Cancer

This research trial studies neuropsychological (learning, remembering or thinking) and
behavioral testing in younger patients with cancer. Collecting information over time from a
series of tests may help doctors develop effective tests to measure neuropsychological and
behavioral function of patients with cancer.

PRIMARY OBJECTIVES:

I. To utilize a standardized battery of age-appropriate neuropsychological and behavioral
tests in conjunction with Children's Oncology Group (COG) Phase II and III clinical trials to
evaluate cognitive, social, emotional, and behavioral functioning over time.

II. To institute procedures to ensure a consistent, streamlined, and efficient administration
of the neuropsychological/behavioral tests in a cooperative group setting in order to
maximize compliance with a standardized assessment battery conducted at 3 standardized time
points.

OUTLINE:

Parent and child participants complete the COG Standard Neuropsychological and Behavioral
Battery testing at 9, 30, and 60 months post-diagnosis in a 1-2 hour session conducted by a
neuropsychologist or psychologist. The Battery consists of tests of intelligence, processing
speed/attention, memory, language preference, general developmental progress, attention and
behavior/social/emotional function, executive function, adoptive function, and quality of
life. Additionally, parents complete a parent-report questionnaire to gather information
about patient's function in terms of attention, memory, executive abilities, and behavioral,
social, and emotional adaption.

Inclusion Criteria:

- The patient must be currently be enrolled or plan to be enrolled on a COG therapeutic
study that aims to examine neuropsychological, social, emotional, and/or behavioral
functioning

- The patient must have receptive and expressive language skills in English, French, or
Spanish; if a patient meets these criteria but the parent/guardian speaks a language
other than English, French, or Spanish, the patient may still be enrolled and tested,
and the parent-report measures should be omitted

- All patients and/or their parents or legal guardians must sign a written informed
consent

- All institutional, Food and Drug Administration (FDA), and National Cancer Institute
(NCI) requirements for human studies must be met

Exclusion Criteria:

- Patients with a history of moderate to profound intellectual disability (i.e.
intelligence quotient [IQ] =< 55) are not eligible for enrollment; PLEASE NOTE:
Children with a prior history of attention deficit hyperactivity disorder (ADHD) or a
specific learning disability (e.g. dyslexia) are eligible for this study
We found this trial at
161
sites
New Orleans, Louisiana 70118
Principal Investigator: Lolie C. Yu
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1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
(505) 272-4946
Principal Investigator: John F. Kuttesch
Phone: 505-925-0366
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
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4900 Mueller Boulevard
Austin, Texas 78723
(512) 324-0000
Principal Investigator: Amy C. Fowler
Phone: 512-324-8022
Dell Children's Medical Center of Central Texas Welcome to Dell Children
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2545 Schoenersville Rd
Bethlehem, Pennsylvania 18017
(484) 884-2200
Principal Investigator: Philip M. Monteleone
Phone: 484-884-2201
Lehigh Valley Hospital - Muhlenberg At Lehigh Valley Health Network, we continually go the extra...
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1600 7th Avenue
Birmingham, Alabama 35233
(205) 638-9100
Principal Investigator: Matthew A. Kutny
Phone: 205-934-0309
Children's Hospital of Alabama Children
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666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Principal Investigator: Denise A. Rokitka
Phone: 800-767-9355
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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1 South Prospect Street
Burlington, Vermont 05401
802-656-8990
Principal Investigator: Jessica L. Heath
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1300 Jefferson Park Avenue
Charlottesville, Virginia 22908
434-243-6784
Principal Investigator: William C. Petersen
Phone: 434-243-6303
University of Virginia Cancer Center We are fortunate in having state of the art clinical...
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3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
 1-513-636-4200 
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Phone: 513-636-2799
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11100 Euclid Avenue
Cleveland, Ohio 44106
(216) 844-1000
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Rainbow Babies and Children's Hospital UH Rainbow Babies & Children’s Hospital is a 244-bed, full-service...
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700 Childrens Drive
Columbus, Ohio 43205
(616) 722-2000
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3533 South Alameda Street
Corpus Christi, Texas 78411
(361) 694-5000
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7777 Forest Ln # C840
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(972) 566-7000
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1200 Pleasant Street
Des Moines, Iowa 50309
(515) 241-KIDS
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Blank Children's Hospital Blank Children's Hospital is completely dedicated to meeting the unique health care...
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9981 S Healthpark Dr # 465
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239-343-5000
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100 Michigan Street Northeast
Grand Rapids, Michigan 49503
616.391.9000
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282 Washington St
Hartford, Connecticut 06106
(860) 545-9000
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2500 N State St
Jackson, Mississippi 39216
(601) 984-1000
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524 South Park Street
Kalamazoo, Michigan 49007
(269) 341-7654
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4650 Sunset Blvd
Los Angeles, California 90027
 (323) 660-2450
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8700 Beverly Blvd # 8211
Los Angeles, California 90048
(1-800-233-2771)
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4015 22nd Place
Lubbock, Texas 79410
806-725-0000
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262 Danny Thomas Pl
Memphis, Tennessee 38105
(901) 495-3300
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Phone: 901-595-4644
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601 Children's Lane
Norfolk, Virginia 23507
(757) 668-7000
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Children's Hospital of The King's Daughters Children
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747 52nd St
Oakland, California 94609
(510) 428-3000
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1201 W La Veta Ave
Orange, California 92868
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1717 South Orange Avenue # 100
Orlando, Florida 32806
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5153 North 9th Avenue
Pensacola, Florida 32504
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530 Northeast Glen Oak Avenue
Peoria, Illinois 61603
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South 34th Street
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 215-590-1000
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4401 Penn Avenue
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412-692-5325
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3181 Southwest Sam Jackson Park Road
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503 494-8311
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593 Eddy Street
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401 College Street
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60 Crittenden Blvd # 70
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(585) 275-2121
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7700 Floyd Curl Dr
San Antonio, Texas 78229
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4502 Medical Drive
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3020 Childrens way
San Diego, California 92123
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1 Tampa General Cir
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40 Sunshine Cottage Road
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1600 Rockland Road
Wilmington, Delaware 19803
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Akron, Ohio 44308
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1540 East Hospital Drive
Ann Arbor, Michigan 48109
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13123 E 16th Ave
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(720) 777-1234
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22 South Greene Street
Baltimore, Maryland 21201
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401 North Broadway
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100 E Idaho St
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(208) 381-2711
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Saint Luke's Mountain States Tumor Institute For more than 100 years, St. Luke
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Boston, Massachusetts 02111
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55 Fruit St
Boston, Massachusetts 02114
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Massachusetts General Hospital Cancer Center An integral part of one of the world
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
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Bronx, New York 10467
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Chapel Hill, North Carolina 27599
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3110 MacCorkle Avenue Southeast
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Charlotte, North Carolina 28204
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Chicago, Illinois 60614
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1200 West Harrison Stree
Chicago, Illinois 60607
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5841 S Maryland Ave
Chicago, Illinois 60637
1-773-702-6180
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2049 E 100th St
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(216) 444-2200
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5 Richland Medical Park Dr
Columbia, South Carolina 29203
(803) 434-7000
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4160 John R St #2122
Detroit, Michigan 48201
(313) 833-1785
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Wayne State University/Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
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Detroit, Michigan 48236
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9333 Imperial Highway
Downey, California 90242
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2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
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East Lansing, Michigan 48824
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Fort Myers, Florida 33908
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801 7th Avenue
Fort Worth, Texas 76104
(682) 885-4000
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1600 Southwest Archer Road
Gainesville, Florida 32610
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835 S Van Buren St
Green Bay, Wisconsin 54301
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900 West Faris Rd.
Greenville, South Carolina 29605
(864)455-8898
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Phone: 864-241-6251
BI-LO Charities Children's Cancer Center The BI-LO Charities Children
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Greenville, South Carolina 29605
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30 Prospect Ave
Hackensack, New Jersey 07601
(201) 996-2000
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Hershey, Pennsylvania 17033
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1319 Punahou St
Honolulu, Hawaii 96826
(808) 983-6000
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Houston, Texas 77030
Principal Investigator: Karen R. Rabin
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Hunter Regional Mail Centre, New South Wales
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705 Riley Hospital Dr
Indianapolis, Indiana 46202
(317) 944-5000
Principal Investigator: Kamnesh R. Pradhan
Phone: 800-248-1199
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Indianapolis, Indiana 46260
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Iowa City, Iowa 52242
Principal Investigator: Mariko Sato
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Jacksonville, Florida 32207
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Kansas City, Missouri 64108
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2018 W Clinch Ave
Knoxville, Tennessee 37916
(865) 541-8000
Principal Investigator: Ray C. Pais
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East Tennessee Children's Hospital East Tennessee Children's Hospital is a not-for-profit, private, independent pediatric medical...
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Las Vegas, Nevada 89109
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Las Vegas, Nevada 89135
Principal Investigator: Alan K. Ikeda
Phone: 702-384-0013
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Las Vegas, NV
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1 Medical Center Dr
Lebanon, New Hampshire 03756
 (603) 650-5000
Principal Investigator: Julie Kim
Phone: 800-639-6918
Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
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mi
from
Lebanon, NH
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Lexington, Kentucky
Principal Investigator: Vlad C. Radulescu
Phone: 859-257-3379
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mi
from
Lexington, KY
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94 Old Short Hills Road
Livingston, New Jersey 07039
(973) 322-5000
Saint Barnabas Medical Center As a Barnabas Health facility, Saint Barnabas Medical Center is committed...
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mi
from
Livingston, NJ
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Long Beach, California 90806
Principal Investigator: Pamela H. Kempert
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mi
from
Long Beach, CA
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Los Angeles, California 90095
Principal Investigator: Tom B. Davidson
Phone: 310-825-6708
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mi
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Los Angeles, CA
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