Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery



Status:Archived
Conditions:Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:December 2008

Use our guide to learn which trials are right for you!

Phase II Trial of mTOR Inhibitor, Everolimus (RAD001), in Malignant Pleural Mesothelioma (MPM)


RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth.

PURPOSE: This phase II trial is studying how well everolimus works in treating patients with
pleural malignant mesothelioma that cannot be removed by surgery.


OBJECTIVES:

Primary

- To determine the 4-month progression-free survival in patients with unresectable
malignant pleural mesothelioma treated with everolimus.

Secondary

- To determine the response rate (confirmed and unconfirmed, complete and partial
responses) and disease control rate (response or stable disease) in patients with
measurable disease by RECIST and modified RECIST criteria.

- To determine overall survival of these patients.

- To evaluate the frequency and severity of toxicities associated with this treatment
regimen.

OUTLINE: This is a multicenter study.

Patients receive oral everolimus once daily on days 1-28. Courses repeat every 28 days in
the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed for 3 years.


We found this trial at
126
sites
Portland, Oregon 97225
?
mi
from
Portland, OR
Click here to add this to my saved trials
1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
(505) 272-4946
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
2720 Clare Avenue
Bremerton, Washington 98310
360-479-6154
Olympic Hematology and Oncology We provide outpatient cancer services in a refined environment designed specifically...
?
mi
from
Bremerton, WA
Click here to add this to my saved trials
200 Hawthorne Lane
Charlotte, North Carolina 28233
704-384-4000
Presbyterian Cancer Center at Presbyterian Hospital At Novant Health Presbyterian Medical Center, we are welcoming...
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
1 Hurley Plaza
Flint, Michigan 48503
(810) 262-9000
Hurley Medical Center From its founding in 1908, Hurley Medical Center has devoted itself to...
?
mi
from
Flint, MI
Click here to add this to my saved trials
Gainesville, Florida 30501
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
2700 Wayne Memorial Drive
Goldsboro, North Carolina 27534
(919) 736-1110
Wayne Memorial Hospital, Incorporated Wayne Memorial Hospital, an affiliate of Wayne Health Corporation, is home...
?
mi
from
Goldsboro, NC
Click here to add this to my saved trials
1415 E. Kincaid
Mount Vernon, Washington 98273
360-424-4111
Skagit Valley Hospital Cancer Care Center We know that treatment takes its toll physically, emotionally...
?
mi
from
Mount Vernon, WA
Click here to add this to my saved trials
19500 10th Ave NE # 100
Poulsbo, Washington 98370
(360) 598-7500
Harrison Poulsbo Hematology and Onocology Harrison Poulsbo's new Hematology & Oncology center provides outpatient cancer...
?
mi
from
Poulsbo, WA
Click here to add this to my saved trials
2279 45th Street
Sacramento, California 95817
(916) 734-5800
University of California Davis Cancer Center At UC Davis Comprehensive Cancer Center, specialized teams of...
?
mi
from
Sacramento, CA
Click here to add this to my saved trials
1100 Fairview Avenue North
Seattle, Washington 98109
(206) 667-5000
Fred Hutchinson Cancer Research Center At Fred Hutchinson Cancer Research Center, our interdisciplinary teams of...
?
mi
from
Seattle, WA
Click here to add this to my saved trials
1959 NE Pacific St
Seattle, Washington 98195
(206) 598-4100
University Cancer Center at University of Washington Medical Center The Division of Radiation Oncology's work...
?
mi
from
Seattle, WA
Click here to add this to my saved trials
201 16th Avenue East
Seattle, Washington 98112
(206) 326-3000
Group Health Central Hospital Group Health Cooperative is a member-governed, nonprofit health care system that...
?
mi
from
Seattle, WA
Click here to add this to my saved trials
601 South Sherman Street
Spokane, Washington 99202
(509) 228-1000
Cancer Care Northwest - Spokane South Cancer Care Northwest is the Inland Northwest’s premier cancer...
?
mi
from
Spokane, WA
Click here to add this to my saved trials
820 North Chelan Avenue
Wenatchee, Washington 98801
509) 663-8711
Wenatchee Valley Medical Center Established on July 21, 2013, Confluence Health is an affiliation between...
?
mi
from
Wenatchee, WA
Click here to add this to my saved trials
Ann Arbor, Michigan 48706
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Ann Arbor, Michigan 48106
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
5301 East Huron River Drive
Ann Arbor, Michigan 48106
1.877.590.5995
CCOP - Michigan Cancer Research Consortium The Community Clinical Oncology Program (CCOP) is a comprehensive...
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
1500 East Medical Center Drive
Ann Arbor, Michigan 48109
800-865-1125
University of Michigan Comprehensive Cancer Center The U-M Comprehensive Cancer Center's mission is the conquest...
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
205 Palmer Ave.
Bellefontaine, Ohio 43311
937.592.4015
Mary Rutan Hospital The hospital was endowed by the sale of a farm in Ridgeway...
?
mi
from
Bellefontaine, OH
Click here to add this to my saved trials
801 N. 29th St
Billings, Montana 59107
406.238.2500
Billings Clinic - Downtown Based in Billings, Montana, Billings Clinic is a community-governed health care...
?
mi
from
Billings, MT
Click here to add this to my saved trials
1101 N 27th St # 201
Billings, Montana 59101
(406) 237-3585
St. Vincent Healthcare Cancer Care Services The Sisters of Charity of Leavenworth, Kansas, founded St....
?
mi
from
Billings, MT
Click here to add this to my saved trials
90 Poly Drive, Suite 2
Billings, Montana 59101
(406) 237-5460
Montana Cancer Consortium CCOP The Montana Cancer Consortium is a nonprofit organization whose mission is...
?
mi
from
Billings, MT
Click here to add this to my saved trials
Boulder, Colorado 80309
(303) 492-1411
University of Colorado, Boulder As the flagship university of the state of Colorado, CU-Boulder is...
?
mi
from
Boulder, CO
Click here to add this to my saved trials
931 Highland Blvd
Bozeman, Montana 59715
(406) 585-5070
Bozeman Deaconess Cancer Center Bozeman Deaconess Cancer Center provides the latest cancer technologies and treatment...
?
mi
from
Bozeman, MT
Click here to add this to my saved trials
6501 E 2nd St
Casper, Wyoming 82609
(307) 235-5433
Rocky Mountain Oncology Rocky Mountain Oncology Center is a spacious, comfortable, state-of-the-art 19,000 square foot...
?
mi
from
Casper, WY
Click here to add this to my saved trials
505 S Plummer Ave
Chanute, Kansas 66720
(620) 431-7580
Cancer Center of Kansas, PA - Chanute Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Chanute, KS
Click here to add this to my saved trials
272 Hospital Rd
Chillicothe, Ohio 45601
740-779-7500
Adena Regional Medical Center Since 1895, Adena Health System has remained focused on its commitment...
?
mi
from
Chillicothe, OH
Click here to add this to my saved trials
9280 SE Sunnybrook Blvd #100
Clackamas, Oregon 97015
(503) 513-3300
Clackamas Radiation Oncology Center State-of-the-art technology and compassionate care come together at Clackamas Radiation Oncology...
?
mi
from
Clackamas, OR
Click here to add this to my saved trials
111 S Grant Avenue
Columbus, Ohio 43215
(614) 566-4321
?
mi
from
Columbus, OH
Click here to add this to my saved trials
?
mi
from
Columbus, OH
Click here to add this to my saved trials
5100 W Broad St
Columbus, Ohio 43228
(614) 544-1000
Doctors Hospital Nationally recognized for care quality and patient safety and satisfaction, Doctors Hospital is...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
793 West State Street
Columbus, Ohio 43222
614-234-5000
Mount Carmel Health - West Hospital Located near downtown Columbus, Mount Carmel West is the...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
142 S Main St
Danville, Virginia 24541
(434) 799-2100
Danville Regional Medical Center For more than 120 years, Danville Regional Medical Center has been...
?
mi
from
Danville, VA
Click here to add this to my saved trials
1 Wyoming St
Dayton, Ohio 45409
(937) 208-2300
?
mi
from
Dayton, OH
Click here to add this to my saved trials
9000 North Main Street
Dayton, Ohio 45415
(937) 734-5800
Samaritan North Cancer Care Center At Good Samaritan Hospital (GSH), our licensed, board-certified staff uses...
?
mi
from
Dayton, OH
Click here to add this to my saved trials
405 W Grand Ave
Dayton, Ohio 45405
(937) 723-3200
Grandview Hospital You'll feel like part of our family when you visit Grandview Medical Center...
?
mi
from
Dayton, OH
Click here to add this to my saved trials
2222 Philadelphia Dr
Dayton, Ohio 45406
(937) 734-2612
Good Samaritan Hospital - Dayton Good Samaritan Hospital (GSH) is passionate about providing the most...
?
mi
from
Dayton, OH
Click here to add this to my saved trials
3123 Research Boulevard Suite 150
Dayton, Ohio 45420
(937) 775-1350
Dayton CCOP We are a regional non-profit cancer research consortium serving the Miami Valley area...
?
mi
from
Dayton, OH
Click here to add this to my saved trials
18101 Oakwood Blvd
Dearborn, Michigan 48124
(313) 593-8620
Oakwood Cancer Center at Oakwood Hospital and Medical Center In today's health care environment, a...
?
mi
from
Dearborn, MI
Click here to add this to my saved trials
2300 N. Edward Street
Decatur, Illinois 62526
217-876-8121
Decatur Memorial Hospital Cancer Care Institute An American flag bearing only 48 stars waved above...
?
mi
from
Decatur, IL
Click here to add this to my saved trials
561 W. Central Avenue
Delaware, Ohio 43015
(740) 615-1000
Grady Memorial Hospital As the center of healthcare in Delaware County, Grady Memorial Hospital is...
?
mi
from
Delaware, OH
Click here to add this to my saved trials
Denville, New Jersey 07834
?
mi
from
Denville, NJ
Click here to add this to my saved trials
4201 St Antoine St
Detroit, Michigan 48201
(313) 577-1429
Wayne State University/Detroit Medical Center Founded in 1868, the Wayne State University School of Medicine...
?
mi
from
Detroit, MI
Click here to add this to my saved trials
2020 Central Ave
Dodge City, Kansas 67801
(620) 227-2488
Cancer Center of Kansas, PA - Dodge City Dr. H.E. Hynes founded Cancer Center of...
?
mi
from
Dodge City, KS
Click here to add this to my saved trials
Edwards, Colorado 81632
?
mi
from
Edwards, CO
Click here to add this to my saved trials
700 West Central
El Dorado, Kansas 67042
(316) 889-0099
Cancer Center of Kansas, PA - El Dorado Dr. H.E. Hynes founded Cancer Center of...
?
mi
from
El Dorado, KS
Click here to add this to my saved trials
200 West Pearl Street
Findlay, Ohio 45840
419-424-0380
Blanchard Valley Medical Associates Blanchard Valley Medical Associates was founded in 1974 by Dr. William...
?
mi
from
Findlay, OH
Click here to add this to my saved trials
Fort Scott, Kansas 66701
(620) 223-8589
Cancer Center of Kansas - Fort Scott Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Fort Scott, KS
Click here to add this to my saved trials
105 Mcknight Drive
Franklin, Ohio 45005
513-424-2111
?
mi
from
Franklin, OH
Click here to add this to my saved trials
Glenwood Springs, Colorado 81601
?
mi
from
Glenwood Springs, CO
Click here to add this to my saved trials
Great Falls, Montana 59405
?
mi
from
Great Falls, MT
Click here to add this to my saved trials
1101 26th Street South
Great Falls, Montana 59405
406.455.5000
Sletten Cancer Institute at Benefis Healthcare Benefis Hospitals has 516 beds at its two campuses...
?
mi
from
Great Falls, MT
Click here to add this to my saved trials
835 Sweitzer St
Greenville, Ohio 45331
(937) 548-1141
Wayne Hospital Stretching back to our roots nearly 100 years ago, Wayne HealthCare has always...
?
mi
from
Greenville, OH
Click here to add this to my saved trials
114 Woodland St, Hartford
Hartford, Connecticut 06105
(860) 714-4000
Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center While better...
?
mi
from
Hartford, CT
Click here to add this to my saved trials
30 13th St
Havre, Montana 59501
(406) 265-2211
Northern Montana Hospital Northern Montana Hospital (NMH) is the center of a comprehensive system of...
?
mi
from
Havre, MT
Click here to add this to my saved trials
2475 Broadway St
Helena, Montana 59601
(406) 442-2480
St. Peter's Hospital Welcome to St. Peter’s Hospital, providing premier health care to a five–county...
?
mi
from
Helena, MT
Click here to add this to my saved trials
1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
?
mi
from
Houston, TX
Click here to add this to my saved trials
800 W. Laurel
Independence, Kansas 67301
620-331-4099
Cancer Center of Kansas-Independence Dr. H.E. Hynes founded Cancer Center of Kansas, P. A. in...
?
mi
from
Independence, KS
Click here to add this to my saved trials
205 Northeast Ave
Jackson, Michigan 49201
(517) 788-4800
Foote Memorial Hospital Allegiance Health is a community-owned, locally-governed health system in Jackson, Michigan. We...
?
mi
from
Jackson, MI
Click here to add this to my saved trials
75 Claremont St Ste E
Kalispell, Montana 59901
(406) 752-7600
Glacier Oncology, PLLC Glacier Oncology are physician clinics focusing exclusively on the medical subspecialties of...
?
mi
from
Kalispell, MT
Click here to add this to my saved trials
310 Sunnyview Ln
Kalispell, Montana 59901
(406) 752-5111
Kalispell Regional Medical Center Nestled in the beautiful Flathead Valley of Northwestern Montana, Kalispell Regional...
?
mi
from
Kalispell, MT
Click here to add this to my saved trials
7360 W. Deschutes
Kennewick, Washington 99336
509-783-0144
Columbia Basin Hematology and Oncology Our collaboration with Seattle Cancer Care Alliance gives you convenient...
?
mi
from
Kennewick, WA
Click here to add this to my saved trials
?
mi
from
Kettering, OH
Click here to add this to my saved trials
750 Avenue D West
Kingman, Kansas 67068
(620) 532-3147
Cancer Center of Kansas, PA - Kingman Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Kingman, KS
Click here to add this to my saved trials
Kingsport, Tennessee 37662
?
mi
from
Kingsport, TN
Click here to add this to my saved trials
Knoxville, Tennessee 37920
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
401 N Ewing St
Lancaster, Ohio 43130
(740) 687-8000
Fairfield Medical Center We are people you know offering care you trust. Serving more than...
?
mi
from
Lancaster, OH
Click here to add this to my saved trials
1215 E Michigan Ave
Lansing, Michigan 48912
(517) 364-2890
Sparrow Regional Cancer Center Sparrow has grown to become the region's largest health system, and...
?
mi
from
Lansing, MI
Click here to add this to my saved trials
325 Maine Street
Lawrence, Kansas 66044
(785) 505-5000
Lawrence Memorial Hospital Lawrence Memorial Hospital (LMH), in collaboration with its medical staff, is dedicated...
?
mi
from
Lawrence, KS
Click here to add this to my saved trials
315 W. 15th St.
Liberal, Kansas 67905
(620) 629-6727
Cancer Center of Kansas, PA - Liberal Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Liberal, KS
Click here to add this to my saved trials
Los Angeles, California 90089
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
401 Matthew St
Marietta, Ohio 45750
(740) 376-5000
Strecker Cancer Center at Marietta Memorial Hospital The Memorial Health System's Strecker Cancer Center combines...
?
mi
from
Marietta, OH
Click here to add this to my saved trials
?
mi
from
Marysville, CA
Click here to add this to my saved trials
Michigan City, Indiana 46360
?
mi
from
Michigan City, IN
Click here to add this to my saved trials
500 W Broadway St
Missoula, Montana 59807
(406) 728-2539
Montana Cancer Specialists at Montana Cancer Center MCC is a comprehensive medical oncology, hematology and...
?
mi
from
Missoula, MT
Click here to add this to my saved trials
500 W Broadway St
Missoula, Montana 59802
(406) 543-7271
Montana Cancer Center at St. Patrick Hospital and Health Sciences Center St. Patrick Hospital is...
?
mi
from
Missoula, MT
Click here to add this to my saved trials
Montrose, Colorado 81401
?
mi
from
Montrose, CO
Click here to add this to my saved trials
1330 Coshocton Ave
Mount Vernon, Ohio 43050
(740) 393-9000
Knox Community Hospital A community-owned, 115-bed, not-for-profit hospital located in Mount Vernon, Ohio (approximately 40...
?
mi
from
Mount Vernon, OH
Click here to add this to my saved trials
Naperville, Illinois 60540
?
mi
from
Naperville, IL
Click here to add this to my saved trials
1320 West Main Street
Newark, Ohio 43055
(740) 348-4475
Licking Memorial Cancer Care Program at Licking Memorial Hospital Our Cancer Program has been approved...
?
mi
from
Newark, OH
Click here to add this to my saved trials
1001 Providence Dr
Newberg, Oregon 97132
(503) 537-1555
Providence Newberg Medical Center Providence Health & Services in Oregon, ranked as one of the...
?
mi
from
Newberg, OR
Click here to add this to my saved trials
720 Medical Center Drive
Newton, Kansas 67114
(316) 282-0888
Cancer Center of Kansas, PA - Newton Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Newton, KS
Click here to add this to my saved trials
?
mi
from
Norton, VA
Click here to add this to my saved trials
Oakland, California 94602
?
mi
from
Oakland, CA
Click here to add this to my saved trials
413 Lilly Rd NE
Olympia, Washington 98506
(888) 492-9480
Providence St. Peter Hospital Regional Cancer Center Providence St. Peter Hospital in Olympia, WA, is...
?
mi
from
Olympia, WA
Click here to add this to my saved trials
Orange, California 92868
?
mi
from
Orange, CA
Click here to add this to my saved trials
Oregon City, Oregon 97045
?
mi
from
Oregon City, OR
Click here to add this to my saved trials
1902 S. US Hwy 59
Parsons, Kansas 67357
(620) 421-2855
Cancer Center of Kansas, PA - Parsons Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Parsons, KS
Click here to add this to my saved trials
?
mi
from
Pleasanton, CA
Click here to add this to my saved trials
2601 Electric Ave
Port Huron, Michigan 48060
(810) 985-1500
Mercy Regional Cancer Center at Mercy Hospital The Mercy Regional Cancer Center at St. Joseph...
?
mi
from
Port Huron, MI
Click here to add this to my saved trials
Portland, Oregon 97213
?
mi
from
Portland, OR
Click here to add this to my saved trials
124 Commodore, Ste. A
Pratt, Kansas 67124
(620) 672-2478
Cancer Center of Kansas, PA - Pratt Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Pratt, KS
Click here to add this to my saved trials
1008 Minnequa Avenue
Pueblo, Colorado 81004
719-557-4000
Saint Mary Corwin Medical Center A leader in technology with a legacy of great care,...
?
mi
from
Pueblo, CO
Click here to add this to my saved trials
1100 Reid Pkwy
Richmond, Indiana 47374
(765) 983-3000
Reid Hospital & Health Care Services As you will see on campus and throughout our...
?
mi
from
Richmond, IN
Click here to add this to my saved trials
Rochester, New York 14623
?
mi
from
Rochester, NY
Click here to add this to my saved trials
?
mi
from
Rochester, NY
Click here to add this to my saved trials
800 S Washington Ave
Saginaw, Michigan 48601
(989) 907-8115
Seton Cancer Institute at Saint Mary's - Saginaw At St. Mary's of Michigan, we continue...
?
mi
from
Saginaw, MI
Click here to add this to my saved trials
?
mi
from
Salina, KS
Click here to add this to my saved trials
600 S Santa Fe Ave
Salina, Kansas 67401
(785) 823-1521
Cancer Center of Kansas, PA - Salina Dr. H.E. Hynes founded Cancer Center of Kansas,...
?
mi
from
Salina, KS
Click here to add this to my saved trials
Seattle, Washington 98122
?
mi
from
Seattle, WA
Click here to add this to my saved trials