New Clinical Trials for Parkinson’s Disease

Brain signals in Parkinson's patientParkinson’s disease is the second most common neurodegenerative disorder after Alzheimer’s disease. Although we know what happens that causes Parkinson’s disease, Parkinson’s disease clinical research has a long way to go to figure out why it happens and what we can do to prevent it from happening.

Current Parkinson’s disease clinical trials are studying Parkinson’s disease in animals, gene therapy, neuroprotective treatments, and neural transplantation. There are ongoing Parkinson’s disease clinical trials being conducted to learn more about this debilitating disease.

What is Parkinson’s Disease?

Parkinson’s disease (PD) is a degenerative disorder of the central nervous system that over time leads to a decrease in motor skills and mental capacity. The disease is characterized by tremors mainly in the arms. In its advanced stages patients often develop dementia and have trouble performing everyday tasks. It is also called primary Parkinsonism or idiopathic Parkinson’s disease. It was first documented in 1817. Parkinson’s disease is caused by dopamine in the brain not forming and acting as it should. It is not known why this happens. There are indications that it is a genetic disease and links have been found between Parkinson’s disease and exposure to pesticides.

Parkinson’s Disease Treatments

Treating Parkinson’s disease is usually done through a combination of methods including diet, medications and exercise. Medications that may be prescribed include levodopa, dopamine agonists and MAO-B inhibitors. Physical rehabilitation and exercise can help put off the decline of motor skills and speech therapy has proven helpful. Exercise also helps maintain muscle strength, motor skills and improves constipation (another symptom of Parkinson’s disease). Since this disease progresses treating Parkinson’s disease needs to occur in stages. Medications that are effective at the beginning need to be monitored as the disease progresses. They may become ineffective or start to cause harmful side effects.

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We've found
905 Parkinsons Disease
clinical trials

Parkinson's Disease Clinical Trial
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)
Status: Enrolling
Updated: 1/18/2012
mi
from
Golden Valley, MN
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Parkinson's Disease Clinical Trial
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)
Status: Enrolling
Updated: 1/18/2012
mi
from
Memphis, TN
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Parkinson's Disease Clinical Trial
Vitamin B12 Status and Response to Vitamin B12 Supplementation in Patients With Parkinson's Disease
Status: Enrolling
Updated: 9/8/2006
mi
from
Atlanta, GA
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Gastroenterology, Immunology / Infectious Diseases, Neurology Clinical Trial
Treating H. Pylori in Parkinson's Patients With Motor Fluctuations
Status: Enrolling, Phase III
Updated: 4/21/2008
mi
from
Los Angeles, CA
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Neurology, Orthopedics / Podiatry Clinical Trial
Identification, Prevalence, and Lifespan of Rapid-Onset Dystonia-Parkinsonism
Status: Enrolling
Updated: 12/8/2014
mi
from
Winston-Salem, NC
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Cardiology / Vascular Diseases, Neurology, Other Clinical Trial
Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
Status: Enrolling
Updated: 8/27/2012
mi
from
Rochester, MN
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Parkinson's Disease Clinical Trial
Use of Noninvasive Brain Stimulation in Parkinson's Disease
Status: Enrolling
Updated: 8/17/2012
mi
from
Boston, MA
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
Houston, TX
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
La Jolla, CA
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
New Haven, CT
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Parkinson's Disease Clinical Trial
Fox Investigation for New Discovery of Biomarkers
Status: Enrolling
Updated: 12/17/2013
mi
from
Chicago, IL
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Neurology, Other Clinical Trial
Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
Status: Enrolling, Phase II
Updated: 10/26/2015
mi
from
Durham, NC
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Neurology, Other Clinical Trial
Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
Status: Enrolling, Phase II
Updated: 10/26/2015
mi
from
Portland, OR
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Parkinson's Disease Clinical Trial
A Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AVE8112 in Patients With Parkinson's Disease
Status: Enrolling, Phase I
Updated: 3/1/2013
mi
from
Glendale, CA
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Parkinson's Disease Clinical Trial
Safety, Tolerability and Efficacy of Two Doses of Once Daily P2B001 in Subjects With Early Parkinson's Disease
Status: Enrolling, Phase II, III
Updated: 11/13/2014
mi
from
New Haven, CT
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Parkinson Disease Clinical Trial
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Status: Enrolling
Updated: 5/4/2015
mi
from
Boston, MA
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Parkinson Disease Clinical Trial
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Status: Enrolling
Updated: 5/4/2015
mi
from
San Francisco, CA
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Parkinson Disease Clinical Trial
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Status: Enrolling
Updated: 5/4/2015
mi
from
Durham, NC
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Parkinson Disease Clinical Trial
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Status: Enrolling
Updated: 5/4/2015
mi
from
Philadelphia, PA
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Parkinson's Disease Clinical Trial
National Parkinson Foundation Quality Improvement Initiative
Status: Enrolling
Updated: 9/3/2014
mi
from
Chicago, IL
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Parkinson's Disease Clinical Trial
National Parkinson Foundation Quality Improvement Initiative
Status: Enrolling
Updated: 9/3/2014
mi
from
Gainesville, FL
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Parkinson's Disease Clinical Trial
National Parkinson Foundation Quality Improvement Initiative
Status: Enrolling
Updated: 9/3/2014
mi
from
New York, NY
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Parkinson's Disease Clinical Trial
Does Outpatient Palliative Care Improve Patient-centered Outcomes in Parkinson's Disease?
Status: Enrolling
Updated: 12/10/2015
mi
from
Aurora, CO
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Parkinson's Disease Clinical Trial
ExAblate Transcranial MRgFUS of the Globus Pallidum for Treatment of Parkinson's Disease
Status: Enrolling
Updated: 6/24/2015
mi
from
Baltimore, MD
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Parkinson's Disease Clinical Trial
ExAblate Transcranial MRgFUS of the Globus Pallidum for Treatment of Parkinson's Disease
Status: Enrolling
Updated: 6/24/2015
mi
from
Charlottesville, VA
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Parkinson's Disease Clinical Trial
Relationship Between Symptoms, Retinal Morphology, and the Nigrostriatal Dopamine System in Parkinson's Disease
Status: Enrolling
Updated: 9/29/2015
mi
from
Philadelphia, PA
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Parkinson's Disease Clinical Trial
Using Parkinson's Disease to Study the Role of the Substantia Nigra Pars Reticulata
Status: Enrolling
Updated: 11/25/2015
mi
from
Aurora, CO
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Parkinson Disease Clinical Trial
Efficacy of Isradipine in Early Parkinson Disease
Status: Enrolling, Phase III
Updated: 9/17/2015
mi
from
Chicago, IL
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Parkinson Disease Clinical Trial
Efficacy of Isradipine in Early Parkinson Disease
Status: Enrolling, Phase III
Updated: 9/17/2015
mi
from
San Diego, CA
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Parkinson's Disease Clinical Trial
ExAblate Transcranial MRgFUS of the Subthalamic Nucleus for Treatment of Parkinson's Disease
Status: Enrolling
Updated: 6/24/2015
mi
from
Charlottesville, VA
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Parkinson Disease Clinical Trial
Exogenous Effects of Standard Medical Care (Dopamine) on Motor Learning of an Upper Limb Task in Parkinson Disease
Status: Enrolling
Updated: 1/7/2016
mi
from
Salt Lake City, UT
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Parkinson's Disease Clinical Trial
The Effect of Low Frequency STN DBS on Sleep and Vigilance in Parkinson's Disease (PD) Patients
Status: Enrolling
Updated: 1/12/2016
mi
from
Birmingham, AL
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Parkinson's Disease Clinical Trial
Complementary & Alternative Medicine in Parkinson's Disease (CAM Care in PD)
Status: Enrolling
Updated: 1/12/2016
mi
from
Kenmore, WA
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Parkinson's Disease Clinical Trial
Phase IIb Study of Intranasal Glutathione in Parkinson's Disease
Status: Enrolling, Phase II
Updated: 1/13/2016
mi
from
Seattle, WA
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Parkinson's Disease Clinical Trial
Kinesia 360 Parkinson's Monitoring Study
Status: Enrolling
Updated: 1/14/2016
mi
from
Greenville, SC
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Parkinson's Disease Clinical Trial
The Cyclical Lower-extremity Exercise for Parkinson's Trial
Status: Enrolling, Phase II, III
Updated: 1/27/2016
mi
from
Cleveland, OH
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Parkinson's Disease Dementia (PDD) Clinical Trial
SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)
Status: Enrolling, Phase II
Updated: 2/2/2016
mi
from
Boca Raton, FL
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Parkinson's Disease Dementia (PDD) Clinical Trial
SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)
Status: Enrolling, Phase II
Updated: 2/2/2016
mi
from
Charleston, SC
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Parkinson's Disease Clinical Trial
A Study of Weekly Subcutaneous Injections of SER-214 in Subjects With Parkinson's Disease (PD), to Determine the Safety, Tolerability and Pharmacokinetic (PK) Profile of SER-214
Status: Enrolling, Phase I
Updated: 2/18/2016
mi
from
Birmingham, AL
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Parkinson's Disease Clinical Trial
A Study of Weekly Subcutaneous Injections of SER-214 in Subjects With Parkinson's Disease (PD), to Determine the Safety, Tolerability and Pharmacokinetic (PK) Profile of SER-214
Status: Enrolling, Phase I
Updated: 2/18/2016
mi
from
Hallandale Beach, FL
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Idiopathic Parkinson Disease Clinical Trial
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 in Subjects With Idiopathic Parkinson's Disease
Status: Enrolling, Phase I
Updated: 3/7/2016
mi
from
Baltimore, MD
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Parkinson's Disease Clinical Trial
Cont. of a Study to Evaluate Implanting Peripheral Nerve Grafts Into Subjects With Parkinson's Disease (PD) During DBS
Status: Enrolling, Phase I
Updated: 3/8/2016
mi
from
Lexington, KY
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Asheville, NC
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Atlanta, GA
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Augusta, GA
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Cleveland, OH
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Panama City, FL
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Pasadena, CA
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Parkinson's Disease Clinical Trial
Frontal Cortex and Gait Freezing in Parkinson's Disease: Rehabilitation Impact
Status: Enrolling
Updated: 3/30/2016
mi
from
Portland, OR
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Parkinson Disease Clinical Trial
A Phase 3 Study to Examine the Efficacy, Safety and Tolerability of APL-130277 for the Acute Treatment of OFF Episodes in Patients With Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/31/2016
mi
from
Boca Raton, FL
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Neurology Clinical Trial
Study to Assess the Clinical Benefit and Safety of Droxidopa in Parkinson's Disease
Status: Enrolling, Phase II
Updated: 4/4/2016
mi
from
West Bloomfield, MI
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Parkinson Disease Clinical Trial
An Open-Label Phase 3 Study to Examine the Long-Term Safety, Tolerability and Efficacy of APL-130277 for the Acute Treatment of "OFF" Episodes in Patients With Parkinson's Disease
Status: Enrolling, Phase III
Updated: 4/5/2016
mi
from
Chicago, IL
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Impulse Control Disorders in Parkinson's Disease Clinical Trial
Naltrexone for Impulse Control Disorders in Parkinson's Disease
Status: Enrolling
Updated: 6/12/2012
mi
from
Philadelphia, PA
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Parkinson's Disease Clinical Trial
Use of Noninvasive Brain Stimulation in Parkinson's Disease
Status: Enrolling
Updated: 8/17/2012
mi
from
Boston, MA
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
Atlanta, GA
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
Birmingham, AL
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
Rochester, NY
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
Boston, MA
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
Seattle, WA
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Parkinson Disease Clinical Trial
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Status: Enrolling, Phase II
Updated: 4/7/2015
mi
from
Sunnyvale, CA
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Parkinson's Disease Clinical Trial
7T MRS in Parkinson's Disease
Status: Enrolling
Updated: 12/8/2015
mi
from
Minneapolis, MN
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Parkinson's Disease Clinical Trial
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)
Status: Enrolling
Updated: 1/18/2012
mi
from
New York, NY
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Parkinson's Disease Clinical Trial
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)
Status: Enrolling
Updated: 1/18/2012
mi
from
Glenview, IL
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Parkinson's Disease Clinical Trial
Psychiatric and Cognitive Manifestations of Parkinson's Disease
Status: Enrolling
Updated: 11/18/2015
mi
from
New York, NY
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Parkinson's Disease Clinical Trial
National Parkinson Foundation Quality Improvement Initiative
Status: Enrolling
Updated: 9/3/2014
mi
from
Golden Valley, MN
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Parkinson's Disease Clinical Trial
National Parkinson Foundation Quality Improvement Initiative
Status: Enrolling
Updated: 9/3/2014
mi
from
Sunnyvale, CA
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Parkinson's Disease Clinical Trial
National Parkinson Foundation Quality Improvement Initiative
Status: Enrolling
Updated: 9/3/2014
mi
from
Washington DC,
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Parkinson's Disease Clinical Trial
Fox Investigation for New Discovery of Biomarkers
Status: Enrolling
Updated: 12/17/2013
mi
from
New York, NY
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Gastroenterology, Nephrology / Urology, Neurology Clinical Trial
Behavioral Therapy to Treat Urinary Symptoms in Parkinson Disease
Status: Enrolling, Phase III
Updated: 6/26/2015
mi
from
Birmingham, AL
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Parkinson's Disease Clinical Trial
Mutations Associated With Parkinson s Disease
Status: Enrolling
Updated: 11/22/2014
mi
from
Bethesda, MD
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Parkinson Disease Clinical Trial
Emotional Prosody Treatment in Parkinson's
Status: Enrolling, Phase I, II
Updated: 10/22/2015
mi
from
Gainesville, FL
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Parkinson's Disease Clinical Trial
Safety, Tolerability and Efficacy of Two Doses of Once Daily P2B001 in Subjects With Early Parkinson's Disease
Status: Enrolling, Phase II, III
Updated: 11/13/2014
mi
from
Port Charlotte, FL
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Parkinson's Disease Clinical Trial
Automated Parkinson's Disease (PD) Motor Symptom Assessment for Deep Brain Stimulation (DBS) Programming
Status: Enrolling
Updated: 6/27/2012
mi
from
Minneapolis, MN
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Parkinson Disease Clinical Trial
N-Acetylcysteine for Neuroprotection in Parkinson's Disease
Status: Enrolling, Phase I, II
Updated: 12/7/2015
mi
from
New York, NY
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Parkinson's Disease Clinical Trial
Fatigue and Cardiac Sympathetic Denervation in Parkinson Disease
Status: Enrolling
Updated: 7/29/2014
mi
from
Miami, FL
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Parkinson Disease Clinical Trial
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Status: Enrolling
Updated: 5/4/2015
mi
from
Miami, FL
Click here to add this to my saved trials
Parkinson Disease Clinical Trial
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Status: Enrolling
Updated: 5/4/2015
mi
from
Portland, OR
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Neurology Clinical Trial
A Study to Examine the Efficacy and Safety of Eltoprazine HCl for Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease Patients
Status: Enrolling, Phase II
Updated: 6/1/2015
mi
from
Boca Raton, FL
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Neurology Clinical Trial
Physiological Effects of Nutritional Support in Patients With Parkinson's Disease
Status: Enrolling
Updated: 12/3/2015
mi
from
Philadelphia, PA
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Parkinson Disease Clinical Trial
Motor Training in PD
Status: Enrolling
Updated: 10/29/2015
mi
from
Decatur, GA
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Neurology, Other Clinical Trial
Respiratory Load Magnitude Estimation in PD
Status: Enrolling
Updated: 10/14/2015
mi
from
Gainesville, FL
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Parkinson's Disease Clinical Trial
Effects of Cholinergic Augmentation on Measures of Balance and Gait
Status: Enrolling, Phase II
Updated: 7/31/2014
mi
from
Portland, OR
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Parkinson Disease Clinical Trial
Efficacy of Isradipine in Early Parkinson Disease
Status: Enrolling, Phase III
Updated: 9/17/2015
mi
from
Houston, TX
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Parkinson's Disease Clinical Trial
Trial Comparing Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Parkinson's Disease
Status: Enrolling
Updated: 10/8/2015
mi
from
Phoenix, AZ
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Parkinson's Disease Clinical Trial
Haptoglobin and Iron in Parkinson's Disease
Status: Enrolling
Updated: 1/15/2016
mi
from
Seattle, WA
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Parkinson's Disease Clinical Trial
Motion Immune Magnetic Resonance Imaging (MRI)
Status: Enrolling
Updated: 1/19/2016
mi
from
Durham, NC
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Cardiology / Vascular Diseases, Neurology Clinical Trial
The Effects of Nicotine Chewing Gum in Parkinson's Disease
Status: Enrolling, Phase I
Updated: 1/19/2016
mi
from
Old Westbury, NY
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Parkinson Disease Clinical Trial
Freezing of Gait in Parkinson's Disease
Status: Enrolling
Updated: 1/27/2016
mi
from
Durham, NC
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Neurology, Psychiatry / Psychology, Orthopedics / Podiatry Clinical Trial
Physiological Brain Atlas Development
Status: Enrolling
Updated: 2/2/2016
mi
from
Columbus, OH
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Parkinson's Disease Dementia (PDD) Clinical Trial
SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)
Status: Enrolling, Phase II
Updated: 2/2/2016
mi
from
Chicago, IL
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Parkinson's Disease Clinical Trial
A Study to Assess the PK and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson's Disease
Status: Enrolling, Phase II
Updated: 2/26/2016
mi
from
Tampa, FL
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Parkinson's Disease Clinical Trial
A Study to Assess the PK and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson's Disease
Status: Enrolling, Phase II
Updated: 2/26/2016
mi
from
Little Rock, AR
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Parkinson's Disease Clinical Trial
A Study to Assess the PK and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson's Disease
Status: Enrolling, Phase II
Updated: 2/26/2016
mi
from
Long Beach, CA
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Parkinson's Disease Clinical Trial
A Study to Assess the PK and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson's Disease
Status: Enrolling, Phase II
Updated: 2/26/2016
mi
from
Naples, FL
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Neurology, Psychiatry / Psychology Clinical Trial
Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery
Status: Enrolling
Updated: 3/1/2016
mi
from
Aurora, CO
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Boston, MA
Click here to add this to my saved trials
Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Cincinnati, OH
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Durham, NC
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Oxnard, CA
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Idiopathic Parkinson's Disease Clinical Trial
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Phoenix, AZ
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