Advancing Pre-operative Targeting for Deep Brain Stimulation in the Globus Pallidus Internus



Status:Enrolling by invitation
Conditions:Parkinsons Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - Any
Updated:3/14/2019
Start Date:August 17, 2018
End Date:December 31, 2020

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Advancing Pre-operative Targeting for Deep Brain Stimulation in the Globus Pallidus Internus: Functional Segmentation Based on Probabilistic Tractography

In the proposed pilot project, MRI data will be prospectively collected to show the
feasibility of the segmentation algorithm and the potential relation to final lead
positioning. Patients will be selected from those undergoing GPi DBS placement. This pilot
data will serve as a basis for pursuing funding for a larger trial evaluating the prospective
ability of the 3T targeting study to improve outcomes and decrease complications in GPi DBS
placement. Improved outcomes and patient experience would be expected to further contribute
to our facility as a center of excellence for treatment of movement disorders.


Patient with the diagnosis of Parkinson's Disease selected for placement of globus pallidus
internus (GPi) deep brain stimulator (DBS)
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13400 E. Shea Blvd.
Scottsdale, Arizona 85259
480-301-8000
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4500 San Pablo Rd S
Jacksonville, Florida 32224
(904) 953-2000
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200 First Street SW
Rochester, Minnesota 55905
507-284-2511
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Rochester, MN
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