New Clinical Trials for Bipolar Disorder

Figure represents symptoms of bipolar disorderClinical trials for bipolar disorder are helping to improve the diagnosis and treatment of this medical condition in both children and adults. Through new clinical studies, specialists are gaining a better understanding of the biological basis for bipolar disorder, which allows them to develop safer and more effective treatments for younger patients. Recent bipolar clinical trials have identified links between specific genetic profiles and responses to certain antidepressant drugs used to treat this condition.

If you are interested in enrolling in a bipolar disorder clinical trial, then you may be among the first to receive an experimental treatment not available anywhere else. It should be noted that since these therapies are still experimental, there is no guarantee that it will produce a beneficial effect. If conventional therapies have proven unsuccessful for your condition, you may want to ask your doctor about participating in a bipolar clinical trial.

What is Bipolar Disorder?

Bipolar disorder, also known as manic depression, produces acute mood swings that can include periods of manic emotional highs and extremely depressed lows. The onset of bipolar symptoms usually occur during the late adolescence or early adulthood, although it is possible for children to develop this medical condition. It is caused by an imbalance of chemicals within the brain responsible for regulating the emotions. Specialists believe that it results from a complex set of genetic and environmental factors.

Aside from the severe fluctuations in mood and energy levels, the symptoms of bipolar disorder can make it difficult for patients to maintain relationships or perform well at school or work. Fortunately, there are a number of treatments and therapies which can help them gain some measure of control over their symptoms. The most commonly prescribed treatments for bipolar disorder include a mixture of medications and psychological counseling (psychotherapy).

Bipolar Disorder Treatment

There is no cure available for bipolar disorder, which means that patients will require lifelong treatment, even during the times when they feel emotionally stable. Most patients will be connected with a psychiatrist who is expertly trained in treating this medical condition, and they will guide them through their treatment plan. Depending on the severity, some bipolar patients will require a full medical team that could include social workers, psychologists, and psychiatric nurses. In addition to prescribed medications and psychotherapy, patients can also get help from specific support groups.

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453 Bipolar Disorder
clinical trials

Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
2005
mi
from 91732
Asheville, NC
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
1225
mi
from 91732
Dallas, TX
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
1924
mi
from 91732
Decatur, GA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
817
mi
from 91732
Denver, CO
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
224
mi
from 91732
Las Vegas, NV
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
1745
mi
from 91732
Milwaukee, WI
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
1509
mi
from 91732
Minneapolis, MN
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
2184
mi
from 91732
Orlando, FL
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
1218
mi
from 91732
Temple, TX
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
428
mi
from 91732
Tucson, AZ
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Neurology, Psychiatry / Psychology Clinical Trial
The Family VOICE Study
Status: Enrolling
Updated: 12/8/2015
2301
mi
from 91732
Baltimore, MD
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Psychiatry / Psychology Clinical Trial
Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder
Status: Enrolling
Updated: 7/1/2013
2578
mi
from 91732
Boston, MA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2101
mi
from 91732
Gainesville, FL
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1161
mi
from 91732
Oklahoma City, OK
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Neurology, Psychiatry / Psychology Clinical Trial
Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations
Status: Enrolling, Phase I
Updated: 12/31/1969
2437
mi
from 91732
Bronx, NY
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1919
mi
from 91732
Atlanta, GA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2301
mi
from 91732
Baltimore, MD
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1880
mi
from 91732
Cincinnati, OH
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Self Focus in Bipolar Disorder: A Functional Magnetic Resonance Imaging (fMRI) Study
Status: Enrolling
Updated: 8/28/2017
2578
mi
from 91732
Boston, MA
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Psychiatry / Psychology Clinical Trial
Role Functioning Changes NOS
Status: Enrolling, Phase
Updated: 3/30/2018
1730
mi
from 91732
Chicago, IL
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Psychiatry / Psychology Clinical Trial
Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders
Status: Enrolling, Phase IV
Updated: 12/31/1969
2320
mi
from 91732
Miami, FL
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BIPOLAR DISORDER Clinical Trial
DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder
Status: Enrolling, Phase IV
Updated: 1/6/2016
2302
mi
from 91732
Baltimore, MD
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BIPOLAR DISORDER Clinical Trial
Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs
Status: Enrolling, Phase IV
Updated: 6/1/2016
2432
mi
from 91732
New York, NY
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Psychiatry / Psychology Clinical Trial
Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1225
mi
from 91732
Dallas, TX
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
1225
mi
from 91732
Dallas, TX
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
1165
mi
from 91732
Oklahoma City, OK
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
2248
mi
from 91732
Rochester, NY
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
1568
mi
from 91732
Saint Louis, MO
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness
Status: Enrolling
Updated: 3/13/2018
1729
mi
from 91732
Chicago, IL
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Psychiatry / Psychology Clinical Trial
The Role of Dysmyelination in Cognitive Impairment of Psychotic Spectrum Disorders
Status: Enrolling, Phase
Updated: 4/19/2018
2434
mi
from 91732
New York, NY
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
1919
mi
from 91732
Atlanta, GA
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
1223
mi
from 91732
Desoto, TX
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
1611
mi
from 91732
Flowood, MS
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
1341
mi
from 91732
Kansas City, MO
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
2319
mi
from 91732
Lauderhill, FL
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
73
mi
from 91732
Oceanside, CA
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Endocrinology, Psychiatry / Psychology Clinical Trial
Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1212
mi
from 91732
Austin, TX
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Endocrinology, Psychiatry / Psychology Clinical Trial
Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1354
mi
from 91732
Houston, TX
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Endocrinology, Psychiatry / Psychology Clinical Trial
Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
110
mi
from 91732
National City, CA
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1212
mi
from 91732
Austin, TX
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2388
mi
from 91732
Berlin, NJ
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2489
mi
from 91732
Farmington, CT
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
14
mi
from 91732
Glendale, CA
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1463
mi
from 91732
Little Rock, AR
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1463
mi
from 91732
Little Rock, AR
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
351
mi
from 91732
Oakland, CA
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2218
mi
from 91732
Raleigh, NC
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
1919
mi
from 91732
Atlanta, GA
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
1919
mi
from 91732
Atlanta, GA
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
2102
mi
from 91732
Charlotte, NC
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
22
mi
from 91732
Culver City, CA
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
1161
mi
from 91732
Oklahoma City, OK
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
26
mi
from 91732
Panorama City, CA
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
1411
mi
from 91732
Shreveport, LA
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Endocrinology, Psychiatry / Psychology Clinical Trial
Saxenda® in Obese or Overweight Patients With Stable Bipolar Disorder (Investigator Initiated)
Status: Enrolling, Phase II
Updated: 12/31/1969
1891
mi
from 91732
Mason, OH
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Psychiatry / Psychology Clinical Trial
Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression
Status: Enrolling, Phase
Updated: 12/31/1969
2432
mi
from 91732
New York, NY
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BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1162
mi
from 91732
Oklahoma City, OK
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BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2248
mi
from 91732
Rochester, NY
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BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
1911
mi
from 91732
Smyrna, GA
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BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
53
mi
from 91732
Wildomar, CA
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Psychiatry / Psychology Clinical Trial
A Trial of Single- and Multiple-doses of Aripiprazole in Adult Subjects With Schizophrenia or Bipolar I Disorder
Status: Enrolling, Phase I
Updated: 12/31/1969
20
mi
from 91732
Garden Grove, CA
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Psychiatry / Psychology Clinical Trial
Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
2277
mi
from 91732
Bethesda, MD
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BIPOLAR DISORDER Clinical Trial
Impact of Pregnancy and the Postpartum Period on Women With Bipolar Disorder
Status: Enrolling, Phase I
Updated: 8/3/2009
2578
mi
from 91732
Boston, MA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients
Status: Enrolling, Phase I, II
Updated: 11/1/2010
33
mi
from 91732
Irvine, CA
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Psychiatry / Psychology Clinical Trial
National Pregnancy Registry for Atypical Antipsychotics
Status: Enrolling, Phase
Updated: 12/31/1969
2578
mi
from 91732
Boston, MA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Early Intervention for Youth at Risk for Bipolar Disorder
Status: Enrolling, Phase II, III
Updated: 2/17/2014
810
mi
from 91732
Boulder, CO
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Neurology, Psychiatry / Psychology, Other Clinical Trial
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
Status: Enrolling
Updated: 1/16/2018
2564
mi
from 91732
East Providence, RI
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Psychiatry / Psychology Clinical Trial
Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder
Status: Enrolling
Updated: 10/29/2015
2578
mi
from 91732
Boston, MA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
2578
mi
from 91732
Boston, MA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
1357
mi
from 91732
Houston, TX
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
1656
mi
from 91732
Madison, WI
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
327
mi
from 91732
Palo Alto, CA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
570
mi
from 91732
Salt Lake City, UT
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Psychiatry / Psychology Clinical Trial
Real-Time Mobile Cognitive Behavioral Intervention for Serious Mental Illness
Status: Enrolling, Phase III
Updated: 1/10/2014
103
mi
from 91732
San Diego, CA
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BIPOLAR DISORDER Clinical Trial
Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder-Not Otherwise Specified
Status: Enrolling
Updated: 3/20/2014
328
mi
from 91732
Palo Alto, CA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2302
mi
from 91732
Baltimore, MD
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2310
mi
from 91732
Boca Raton, FL
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2208
mi
from 91732
Charlottesville, VA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2036
mi
from 91732
Garfield Heights, OH
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
2388
mi
from 91732
Marlton, NJ
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