Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia



Status:Recruiting
Conditions:Peripheral Vascular Disease, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:2/7/2018
Start Date:August 2014
End Date:December 2019
Contact:Flora S Siami, MPH
Email:ssiami@neriscience.com
Phone:617-972-3317

Use our guide to learn which trials are right for you!

Best Endovascular Versus Best Surgical Therapy in Patients With Critical Limb Ischemia

This study will compare the effectiveness of best available surgical treatment with best
available endovascular treatment in adults with critical limb ischemia (CLI) who are eligible
for both treatment options.

Male and female subjects aged 18 years or older will be randomized to receive either open
surgical treatment or endovascular treatment. They will be followed for at least 2 years and
up to 4 years and 2 months after treatment to primarily assess survival and major adverse
limb events in the index or treated limb, and secondarily, to determine clinical and cost
effectiveness outcomes after treatment. These outcomes (survival-free of major limb events
and clinical, functional and cost effectiveness) will be compared within two cohorts of
subjects: those with an available single-segment great saphenous vein, and those with an
alternative conduit. The null hypotheses for both cohorts is that there will be no difference
in MALE-free survival between best endovascular therapy and best surgical therapy.

Inclusion Criteria:

1. Male or female, age 18 years or older.

2. Infrainguinal PAOD (occlusive disease of the arteries below the inguinal ligament).

3. CLI, defined as arterial insufficiency with gangrene, non-healing ischemic ulcer, or
rest pain consistent with Rutherford categories 4-6.

4. Candidate for both endovascular and open infrainguinal revascularization as judged by
the treating investigators

5. Adequate aortoiliac inflow.

6. Adequate popliteal, tibial or pedal revascularization target defined as an
infrainguinal arterial segment distal to the area of stenosis/occlusion which can
support a distal anastomosis of a surgical bypass.

7. Willingness to comply with protocol, attend follow-up appointments, complete all study
assessments, and provide written informed consent.

Exclusion Criteria:

1. Presence of a popliteal aneurysm (>2 cm) in the index limb.

2. Life expectancy of less than 2 years due to reasons other than PAOD.

3. Excessive risk for surgical bypass (as determined by the operating surgeon and the CLI
Team)

4. Planned above ankle amputation on ipsilateral limb within 4 weeks of index procedure.

5. Active vasculitis, Buerger's disease, or acute limb-threatening ischemia

6. Any prior index limb infrainguinal stenting or stent grafting associated with
significant restenosis within 1 cm of stent or stent-graft, unless the
occlusion/restenosis site is outside the intended treatment zone (i.e.,. a tibial
vessel that is not currently intended to be revascularized as a part of the treatment
for CLI).

7. Any of the following procedures performed on the index limb within 3 months prior to
enrollment:

1. Infrainguinal balloon angioplasty, atherectomy, stent, or stentgraft;

2. Infrainguinal bypass with either venous or prosthetic conduit

8. Open surgical inflow procedure (aortofemoral, axillofemoral, iliofemoral,
thoracofemoral or femorofemoral bypass) within 6 weeks prior to enrollment

9. Current chemotherapy or radiation therapy.

10. Absolute contraindication to iodinated contrast due to prior near-fatal anaphylactoid
reaction (laryngospasm, bronchospasm, cardiorespiratory collapse, or equivalent) which
would preclude patient participation in angiographic procedures.

11. Pregnancy or lactation.

12. Administration of an investigational drug for PAD within 30 days of randomization.

13. Participation in a clinical trial (except observational studies) within the previous
30 days.

14. Prior enrollment or randomization into BEST-CLI.
We found this trial at
151
sites
2049 E 100th St
Cleveland, Ohio 44106
(216) 444-2200
Principal Investigator: Mehdi Shishehbor, DO, MPH
Cleveland Clinic Foundation The Cleveland Clinic (formally known as The Cleveland Clinic Foundation) is a...
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
201 Dowman Dr
Atlanta, Georgia 30303
(404) 727-6123
Principal Investigator: Khusrow Niazi, MD
Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
Principal Investigator: Marc Passman, MD
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
Principal Investigator: Glenn LaMuraglia, MD
?
mi
from
Boston, MA
Click here to add this to my saved trials
800 Washington St
Boston, Massachusetts 02111
(617) 636-5000
Principal Investigator: Mark Iafrati, MD
Tufts Medical Center Tufts Medical Center is an internationally-respected academic medical center – a teaching...
?
mi
from
Boston, MA
Click here to add this to my saved trials
75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Principal Investigator: Michael Belkin, MD
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
?
mi
from
Boston, MA
Click here to add this to my saved trials
330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Principal Investigator: Allen Hamdan, MD
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
?
mi
from
Boston, MA
Click here to add this to my saved trials
3550 Jerome Avenue
Bronx, New York 10467
(718) 920-4321
Montefiore Medical Center As the academic medical center and University Hospital for Albert Einstein College...
?
mi
from
Bronx, NY
Click here to add this to my saved trials
Durham, North Carolina 27710
(919) 684-8111
Principal Investigator: Cynthia Shortell, MD
Duke University Younger than most other prestigious U.S. research universities, Duke University consistently ranks among...
?
mi
from
Durham, NC
Click here to add this to my saved trials
Gainesville, Florida 32611
(352) 392-3261
Principal Investigator: Kristina Giles, MD
University of Florida Gainesville UF has a long history of established programs in international education,...
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
1 Gustave L Levy Pl # 271
New York, New York 10029
 (212) 241-6500
Principal Investigator: Ageliki Vouyouka, MD
Mount Sinai Med Ctr Founded in 1852, The Mount Sinai Hospital is a 1,171-bed, tertiary-care...
?
mi
from
New York, NY
Click here to add this to my saved trials
Ocala, Florida 34471
Principal Investigator: Gregory Von Mering, MD
?
mi
from
Ocala, FL
Click here to add this to my saved trials
22 Bramhall St
Portland, Maine 04102
(207) 662-0111
Principal Investigator: Elizabeth Blazick, MD
Maine Medical Center One of the country's consistently highest rated hospitals is right in your...
?
mi
from
Portland, ME
Click here to add this to my saved trials
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Principal Investigator: Erica Mitchell, MD
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
?
mi
from
Portland, OR
Click here to add this to my saved trials
593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Principal Investigator: Jeffrey Slaiby, MD
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
?
mi
from
Providence, RI
Click here to add this to my saved trials
601 Elmwood Avenue
Rochester, New York 14642
(585) 275-2100
Principal Investigator: Michael Stoner, MD
Phone: 585-275-6772
Univ of Rochester Medical Center One of the nation's top academic medical centers, the University...
?
mi
from
Rochester, NY
Click here to add this to my saved trials
201 Presidents Circle
Salt Lake City, Utah 84108
801) 581-7200
Principal Investigator: Benjamin Brooke, MD
University of Utah Research is a major component in the life of the U benefiting...
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
1 Tampa General Cir
Tampa, Florida 33606
(813) 844-7000
Principal Investigator: Paul Armstrong, MD
Tampa General Hospital In a diverse city known for its rich culture and beautiful beaches,...
?
mi
from
Tampa, FL
Click here to add this to my saved trials
1000 W Carson St
Torrance, California 90502
Principal Investigator: Rodney White, MD
?
mi
from
Torrance, CA
Click here to add this to my saved trials
Albany, New York 12208
Principal Investigator: R. Clement Darling, III, MD
?
mi
from
Albany, NY
Click here to add this to my saved trials
Albuquerque, New Mexico 87102
Principal Investigator: Stephen Henao, MD
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
1501 San Pedro Drive Southeast
Albuquerque, New Mexico 87108
Principal Investigator: Erika Ketteler, MD
Phone: 773-544-2280
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
Ann Arbor, Michigan 48106
Principal Investigator: Brian Halloran, MD
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
1500 E Medical Center Dr
Ann Arbor, Michigan 48109
(734) 936-4000
Principal Investigator: Peter Henke, MD
University of Michigan Health System The University of Michigan is home to one of the...
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
1968 Peachtree Rd NW
Atlanta, Georgia 30309
(404) 605-5000
Principal Investigator: Eyal Ben-Arie, MA
Piedmont Hospital For more than a century, Piedmont Healthcare has been a recognized leader in...
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
12605 East 16th Avenue
Aurora, Colorado 80045
720-848-0000
Principal Investigator: Kevin Rogers, MD, MSc
University of Colorado Hospital, Site Top medical professionals, superior medicine and progressive change make University...
?
mi
from
Aurora, CO
Click here to add this to my saved trials
Baltimore, Maryland 21201
Principal Investigator: Robert Crawford, MD
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
1800 Orleans St.
Baltimore, Maryland 21287
410-955-5000
Principal Investigator: Ying Wei Lum, MD
Johns Hopkins Hospital Patients are the focus of everything we do at The Johns Hopkins...
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
4501 North Charles Street
Baltimore, Maryland 21210
Principal Investigator: Bernadette Aulivola, MD
Phone: 773-208-2688
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baton Rouge, Louisiana 70806
Principal Investigator: Joseph Griffin, MD
?
mi
from
Baton Rouge, LA
Click here to add this to my saved trials
Boston, Massachusetts 02118
Principal Investigator: Jeffrey Kalish, MD
?
mi
from
Boston, MA
Click here to add this to my saved trials
Boston, Massachusetts 02130
Principal Investigator: Scott Kinlay, MD
?
mi
from
Boston, MA
Click here to add this to my saved trials
Brighton, Massachusetts 02135
Principal Investigator: Frank Pomposelli, MD
?
mi
from
Brighton, MA
Click here to add this to my saved trials
Browns Mills, New Jersey 08015
Principal Investigator: Richard Kovach, MD
?
mi
from
Browns Mills, NJ
Click here to add this to my saved trials
Buffalo, New York 14215
Principal Investigator: Hasan Dosluoglu, MD
?
mi
from
Buffalo, NY
Click here to add this to my saved trials
Burlington, Vermont 05405
Principal Investigator: Julie Adams, MD
?
mi
from
Burlington, VT
Click here to add this to my saved trials
Chapel Hill, North Carolina 27599
(919) 962-2211
Principal Investigator: Kate McGinigle, MD
Univ of North Carolina Carolina’s vibrant people and programs attest to the University’s long-standing place...
?
mi
from
Chapel Hill, NC
Click here to add this to my saved trials
Charleston, South Carolina 29401
?
mi
from
Charleston, SC
Click here to add this to my saved trials
171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Principal Investigator: Thomas Brothers, MD
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Charleston, West Virginia 25304
Principal Investigator: Patrick Stone, MD
?
mi
from
Charleston, WV
Click here to add this to my saved trials
Charlottesville, Virginia 22903
(434) 924-0311
Principal Investigator: Margaret Tracci, MD
University of Virginia The University of Virginia is distinctive among institutions of higher education. Founded...
?
mi
from
Charlottesville, VA
Click here to add this to my saved trials
Chicago, Illinois 60637
Principal Investigator: Ross Milner, MD
?
mi
from
Chicago, IL
Click here to add this to my saved trials
251 E Huron St
Chicago, Illinois 60611
(312) 926-2000
Principal Investigator: Mark Eskandari, MD
Northwestern Memorial Hospital Northwestern Memorial is an academic medical center hospital where the patient comes...
?
mi
from
Chicago, IL
Click here to add this to my saved trials
1653 W. Congress Parkway
Chicago, Illinois 60612
(312) 942-5000
Principal Investigator: Ulku Cenk Turba, MD
Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
?
mi
from
Chicago, IL
Click here to add this to my saved trials
2500 Metrohealth Dr
Cleveland, Ohio 44109
Principal Investigator: Robert Hacker, MD
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Cleveland, Ohio
Principal Investigator: Vikram Kashyap, MD
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Columbia, Missouri 65211
(573) 882-2121
Principal Investigator: Todd Vogel, MD
University of Missouri T he University of Missouri was founded in 1839 in Columbia, Mo.,...
?
mi
from
Columbia, MO
Click here to add this to my saved trials
Columbus, Ohio 43214
Principal Investigator: Gary Ansel, MD
?
mi
from
Columbus, OH
Click here to add this to my saved trials
281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Principal Investigator: Jean Starr, MD
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
4500 S. Lancaster Rd.
Dallas, Texas 75216
800-849-3597
Principal Investigator: J. Gregory Modrall, MD
Dallas VA Medical Center VA North Texas Health Care System (VANTHCS) is a progressive health...
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Davenport, Iowa 52803
Principal Investigator: Nicolas Shammas, MD
?
mi
from
Davenport, IA
Click here to add this to my saved trials
2300 N Edward St
Decatur, Illinois 62526
(217) 876-8121
Principal Investigator: Jeffrey Trachtenberg, MD
Decatur Memorial Hospital An American flag bearing only 48 stars waved above Decatur Memorial Hospital...
?
mi
from
Decatur, IL
Click here to add this to my saved trials
Denver, Colorado 80220
Principal Investigator: Ehrin Armstrong, MD
?
mi
from
Denver, CO
Click here to add this to my saved trials
2799 W Grand Blvd
Detroit, Michigan 48202
(313) 916-2600
Principal Investigator: Timothy Nypaver, MD
Henry Ford Hospital Founded in 1915 by auto pioneer Henry Ford and now one of...
?
mi
from
Detroit, MI
Click here to add this to my saved trials
Durham, North Carolina 27705
Principal Investigator: Leila Mureebe, MD
?
mi
from
Durham, NC
Click here to add this to my saved trials
350 Engle St
Englewood, New Jersey 07631
(201) 894-3000
Principal Investigator: Thomas Bernik, MD
Englewood Hospital and Medical Center Englewood Hospital was incorporated in 1888 as a non-profit, non-sectarian...
?
mi
from
Englewood, NJ
Click here to add this to my saved trials
3300 Gallows Road
Falls Church, Virginia 22042
Principal Investigator: Dipankar Mukherjee, MD
?
mi
from
Falls Church, VA
Click here to add this to my saved trials
Flemington, New Jersey 08822
Principal Investigator: Andrey Espinoza, MD
?
mi
from
Flemington, NJ
Click here to add this to my saved trials
Flint, Michigan 98507
Principal Investigator: Robert Molnar, MD
?
mi
from
Flint, MI
Click here to add this to my saved trials
701 Grove Rd
Greenville, South Carolina 29605
(864) 455-7000
Principal Investigator: Tod Hanover, MD
Greenville Memorial Hospital Greenville Memorial Medical Campus is a regional referral center for the diagnosis...
?
mi
from
Greenville, SC
Click here to add this to my saved trials
Hanover, New Hampshire 03755
?
mi
from
Hanover, NH
Click here to add this to my saved trials
Hartford, Connecticut 06105
Principal Investigator: Scott Fecteau, MD
?
mi
from
Hartford, CT
Click here to add this to my saved trials
500 University Dr
Hershey, Pennsylvania 17033
(717) 531-6955
Principal Investigator: Faisal Aziz, MD
Penn State Milton S. Hershey Medical Center Penn State Milton S. Hershey Medical Center, Penn...
?
mi
from
Hershey, PA
Click here to add this to my saved trials
Honolulu, Hawaii 96817
Principal Investigator: Peter Schneider, MD
?
mi
from
Honolulu, HI
Click here to add this to my saved trials
Houston, Texas 77030
Principal Investigator: Ali Azizzadeh, MD
?
mi
from
Houston, TX
Click here to add this to my saved trials
2002 Holcombe Blvd
Houston, Texas 77030
(713) 791-1414
Principal Investigator: Neal Barshes, MD, MPH
Michael E. Debakey VA Medical Center The Michael E. DeBakey VA Medical Center serves as...
?
mi
from
Houston, TX
Click here to add this to my saved trials
Indianapolis, Indiana 46202
Principal Investigator: Raghu Motaganahalli, MD
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Irvine, California 92697
949-824-5011
Principal Investigator: Nii-Kabu Kabutey, MD
University of California, Irvine Since 1965, the University of California, Irvine has combined the strengths...
?
mi
from
Irvine, CA
Click here to add this to my saved trials
Kansas City, Missouri 64116
Principal Investigator: Scott Kujath, MD
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Kingsport, Tennessee 37660
Principal Investigator: Chris Metzger, MD
?
mi
from
Kingsport, TN
Click here to add this to my saved trials
Knoxville, Tennessee 37920
Principal Investigator: Laura Findeiss, MD
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
1900 South Avenue
La Crosse, Wisconsin 54601
Principal Investigator: Ezana Azene, MD
?
mi
from
La Crosse, WI
Click here to add this to my saved trials
La Jolla, California 92037
Principal Investigator: John Lane, MD
?
mi
from
La Jolla, CA
Click here to add this to my saved trials
La Jolla, California 92037
Principal Investigator: John Lane, MD
?
mi
from
La Jolla, CA
Click here to add this to my saved trials
Little Rock, Arkansas 72205
Principal Investigator: Matthew Smeds, MD
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
11234 Anderson St
Loma Linda, California 92354
(909) 558-4000
Principal Investigator: Ahmed Abou-Zamzam, MD
Loma Linda University Medical Center An outgrowth of the original Sanitarium on the hill in...
?
mi
from
Loma Linda, CA
Click here to add this to my saved trials
Loma Linda, California 92357
Principal Investigator: Christian Bianchi, MD
?
mi
from
Loma Linda, CA
Click here to add this to my saved trials
Long Beach, California 90822
Principal Investigator: Ian Gordon, MD
Phone: 562-618-1656
?
mi
from
Long Beach, CA
Click here to add this to my saved trials
Los Angeles, California 90048
Principal Investigator: Aamir Shah, MD
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90073
Principal Investigator: Hugh Gelabert, MD
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90033
Principal Investigator: Vincent Rowe, MD
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90095
Principal Investigator: Peter Lawrence, MD
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
4733 Sunset Blvd
Los Angeles, California 90027
(800) 954-8000
Principal Investigator: Kaushal Patel, MD
Kaiser Permanente Los Angeles Medical Center We've been there for you in the past, providing...
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Madison, Wisconsin 53713
Principal Investigator: Victor Weiss, MD
?
mi
from
Madison, WI
Click here to add this to my saved trials
Madison, Wisconsin 53706
(608) 263-2400
Principal Investigator: John Hoch, MD
University of Wisconsin-Madison In achievement and prestige, the University of Wisconsin-Madison has long been recognized...
?
mi
from
Madison, WI
Click here to add this to my saved trials
Merrillville, Indiana 46410
?
mi
from
Merrillville, IN
Click here to add this to my saved trials
8900 N Kendall Dr
Miami, Florida 33176
(786) 596-1960
Principal Investigator: James Benenati, MD
Baptist Hospital of Miami Since 1960, Baptist Hospital of Miami has been one of the...
?
mi
from
Miami, FL
Click here to add this to my saved trials
4300 Alton Road
Miami Springs, Florida 33140
Principal Investigator: Robert Beasley, MD
?
mi
from
Miami Springs, FL
Click here to add this to my saved trials
8701 W Watertown Plank Rd
Milwaukee, Wisconsin
(414) 955-8296
Principal Investigator: Parag Patel, MD
Medical College of Wisconsin The Medical College (MCW) of Wisconsin is a major national research...
?
mi
from
Milwaukee, WI
Click here to add this to my saved trials
Milwaukee, Wisconsin 53295
Principal Investigator: Kellie Brown, MD
?
mi
from
Milwaukee, WI
Click here to add this to my saved trials
Minneapolis, Minnesota 55407
Principal Investigator: Jason Alexander, MD
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
Minneapolis, Minnesota 55417
Principal Investigator: Daniel Ihnat, MD
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
20 York St, N20 York St,
New Haven, Connecticut 06520
(203) 688-4242
Principal Investigator: Carlos Mena-Hurtado, MD
Yale-New Haven Hospital Relying on the skill and expertise of more than 4,500 university and...
?
mi
from
New Haven, CT
Click here to add this to my saved trials
1514 Jefferson Hwy.
New Orleans, Louisiana 70121
504-842-3000
Principal Investigator: J. Stephen Jenkins, MD
Ochsner Medical Center Ochsner Medical Center is located near uptown New Orleans and includes acute...
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
New York, New York 10021
?
mi
from
New York, NY
Click here to add this to my saved trials
630 W 168th St
New York, New York
212-305-2862
Principal Investigator: Danielle Bajakian, MD
Phone: 212-305-8665
Columbia University Medical Center Situated on a 20-acre campus in Northern Manhattan and accounting for...
?
mi
from
New York, NY
Click here to add this to my saved trials
Newark, New Jersey 07103
Principal Investigator: Timothy Wu, MD
?
mi
from
Newark, NJ
Click here to add this to my saved trials
Norfolk, Virginia 23507
Principal Investigator: David Dexter, MD
?
mi
from
Norfolk, VA
Click here to add this to my saved trials
Oklahoma City, Oklahoma 73210
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
940 NE 13th St
Oklahoma City, Oklahoma 73190
(405) 271-6458
Principal Investigator: Beau Hawkins, MD
University of Oklahoma Health Sciences Center The OU Health Sciences Center is composed of seven...
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Emile St
Omaha, Nebraska 68198
(402) 559-4000
Principal Investigator: G. Matthew Longo, MD
Univ of Nebraska Med Ctr A vital enterprise in the nation’s heartland, the University of...
?
mi
from
Omaha, NE
Click here to add this to my saved trials