Collection and Storage of Tissue and Blood Samples From Patients With Cancer



Status:Recruiting
Healthy:No
Age Range:18 - Any
Updated:11/28/2018
Start Date:May 15, 2015

Use our guide to learn which trials are right for you!

Patient-Derived Models Tissue Procurement Protocol for the National Cancer Institute (NCI)

This research trial collects and stores tissue and blood samples from patients with cancer.
Collecting and storing samples of tissue and blood from patients with cancer to study in the
laboratory may help scientists create new and better models to learn about cancer and to test
new cancer drugs.

PRIMARY OBJECTIVES:

I. To procure biologic tissues and materials to generate preclinical models of cancer.

OUTLINE:

Tumor tissue and blood samples are procured during procedures that are required for the
patients? clinical management and will be stored via xenograft (transplant to another
species) models or in vitro cell culture for future analysis.

Inclusion Criteria:

- Patients with a histologically or cytologically confirmed diagnosis of cancer who are
being evaluated and/or treated for cancer at participating sites

- Ability to understand and willingness to sign a written informed consent document
indicating their willingness to have their tissue or biologic fluid specimens used for
research as outlined in this protocol

Exclusion Criteria:

- Patients with invasive fungal infections

- Patients with active and/or uncontrolled infections or who are still recovering from
an infection

- Actively febrile patients with uncertain etiology of febrile episode

- All antibiotics should be completed at least 1 week (7 days) prior to collection

- No recurrence of fever or other symptoms related to infection for at least 1 week
(7 days) following completion of antibiotics

- Patients with human immunodeficiency virus (HIV), active or chronic hepatitis (i.e.,
quantifiable hepatitis B virus [HBV]-deoxyribonucleic acid [DNA] and/or positive
hepatitis B surface antigen [HbsAg], quantifiable hepatitis C virus [HCV]-ribonucleic
acid [RNA]) or known history of HCV or HBV without documented resolution; testing for
hepatitis B or other infections for eligibility will be performed only if clinically
indicated

- Tumor tissue or blood collections from patients with benign tumors including desmoid
tumors, carcinoma in situ, or ongoing complete disease response (CR)

- Tumor tissue collected from patients on treatment and demonstrating partial (PR)
or stable disease (SD) response will require pathology confirmation sent to the
coordinating site of viable malignancy and < 90% tumor necrosis; or

- Documentation of clinical progression by the assessing physician

- Blood collection only:

- Blood will not be collected from patients whose disease demonstrates ongoing
partial response or who are currently on treatment with ongoing (i.e., prolonged)
stable disease given the poor rate of model generation from such samples
We found this trial at
139
sites
Las Vegas, Nevada 89128
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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1500 E Duarte Rd
Duarte, California 91010
(626) 256-4673
Principal Investigator: Mihaela C. Cristea
Phone: 800-826-4673
City of Hope Comprehensive Cancer Center City of Hope is a leading research and treatment...
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Duarte, CA
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200 North Park Street
Kalamazoo, Michigan 49007
(269) 382-2500
Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
West Michigan Cancer Center In 1994, Borgess Health Alliance and Bronson Healthcare Group opened the...
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Kalamazoo, MI
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5301 McAuley Drive
Ann Arbor, Michigan 48197
734-712-3456
Principal Investigator: Philip J. Stella
Phone: 208-367-7954
Saint Joseph Mercy Hospital St. Joseph Mercy Ann Arbor Hospital is a 537-bed teaching hospital...
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921 North Oak Park Boulevard
Arroyo Grande, California 93420
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Auburn, Washington 98001
Principal Investigator: John A. Keech
Phone: 253-403-2394
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Augusta, Georgia 30912
Principal Investigator: Sharad A. Ghamande
Phone: 706-721-2388
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Augusta, GA
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12605 East 16th Avenue
Aurora, Colorado 80045
720-848-0000
Principal Investigator: Wells A. Messersmith
Phone: 720-848-0650
University of Colorado Hospital, Site Top medical professionals, superior medicine and progressive change make University...
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Bainbridge Island, Washington 98110
Principal Investigator: John A. Keech
Phone: 253-403-2394
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401 North Broadway
Baltimore, Maryland 21287
410-955-5000
Principal Investigator: Christopher D. Gocke
Phone: 410-955-8804
Johns Hopkins University-Sidney Kimmel Cancer Center The name Johns Hopkins has become synonymous with excellence...
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265 Fremont St
Battle Creek, Michigan 49017
(269) 245-8166
Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
Bronson Battle Creek As a proud member of the Battle Creek community, we believe everyone...
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Birmingham, Alabama 35233
Principal Investigator: Carlo M. Contreras
Phone: 205-934-0309
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Bloomington, Illinois 61701
Principal Investigator: James L. Wade
Phone: 217-876-4740
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1505 Eastland Drive
Bloomington, Illinois 61701
309-662-2102
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare-Bloomington Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood diseases. Our...
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Bolivar, Missouri 65613
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Bonne Terre, Missouri 63628
Principal Investigator: James L. Wade
Phone: 309-243-3605
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Principal Investigator: Geoffrey I. Shapiro
Phone: 877-442-3324
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Boston, MA
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Branson, Missouri 65616
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Bronx, New York 10467
Principal Investigator: Joseph A. Sparano
Phone: 718-379-6866
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Bronx, New York 10461
Principal Investigator: Joseph A. Sparano
Phone: 718-379-6866
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Bronx, New York 10461
Principal Investigator: Joseph A. Sparano
Phone: 718-379-6866
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210 W Walnut St
Canton, Illinois 61520
309-647-5240
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Canton Illinois CancerCare is one of the largest private oncology and hematology...
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211 Saint Francis Drive
Cape Girardeau, Missouri 63703
573-331-3000
Principal Investigator: James L. Wade
Phone: 309-243-3605
Saint Francis Medical Center Saint Francis Medical Center is a 282-bed facility serving more than...
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789 Mt Auburn Rd
Cape Girardeau, Missouri 63703
(573) 519-4725
Principal Investigator: James L. Wade
Phone: 309-243-3605
Southeast Cancer Center SoutheastHEALTH is a far-reaching network of providers and facilities including Southeast Hospital...
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Carbondale, Illinois 62902
Principal Investigator: James L. Wade
Phone: 309-243-3605
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160 S Adams St
Carthage, Illinois 62321
(217) 357-6877
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Carthage Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood...
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Centralia, Illinois 62801
Principal Investigator: James L. Wade
Phone: 309-243-3605
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505 S Plummer Ave
Chanute, Kansas 66720
(620) 431-7580
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - Chanute Dr. H.E. Hynes founded Cancer Center of Kansas,...
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Chapel Hill, North Carolina 27599
Principal Investigator: Elizabeth C. Dees
Phone: 877-668-0683
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1969 W Ogden Ave
Chicago, Illinois 60612
(312) 864-6000
Principal Investigator: Thomas E. Lad
Phone: 312-864-5204
John H. Stroger, Jr. Hospital of Cook County The Level 1 Trauma Center is one...
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12961 27th Ave
Chippewa Falls, Wisconsin 54729
715-738-3700
Principal Investigator: Adedayo A. Onitilo
Phone: 715-393-1400
Marshfield Clinic - Chippewa Center The 15,000 square foot Lake Hallie Center provides urgent care...
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2300 N Edward St
Decatur, Illinois 62526
(217) 876-8121
Principal Investigator: James L. Wade
Phone: 309-243-3605
Decatur Memorial Hospital An American flag bearing only 48 stars waved above Decatur Memorial Hospital...
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210 West McKinley Avenue
Decatur, Illinois 62526
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2020 Central Ave
Dodge City, Kansas 67801
(620) 227-2488
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - Dodge City Dr. H.E. Hynes founded Cancer Center of...
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2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Principal Investigator: James L. Abbruzzese
Phone: 888-275-3853
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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900 W. Clairemont Ave.
Eau Claire, Wisconsin 54701
715 839-3956
Principal Investigator: Adedayo A. Onitilo
Phone: 715-393-1400
Marshfield Clinic Cancer Center at Sacred Heart Marshfield Clinic Cancer Care at Sacred Heart Hospital...
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Effingham, Illinois 62401
Principal Investigator: James L. Wade
Phone: 309-243-3605
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700 West Central
El Dorado, Kansas 67042
(316) 889-0099
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - El Dorado Dr. H.E. Hynes founded Cancer Center of...
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101 S Major St
Eureka, Illinois 61530
309-467-2371
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Eureka Illinois CancerCare is one of the largest private oncology and hematology...
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Federal Way, Washington 98002
Principal Investigator: John A. Keech
Phone: 253-403-2394
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Fort Scott, Kansas 66701
(620) 223-8589
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Fort Scott Dr. H.E. Hynes founded Cancer Center of Kansas,...
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3315 N Seminary St
Galesburg, Illinois 61401
309-344-9269
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Galesburg Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood...
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Galesburg, Illinois 61401
Principal Investigator: James L. Wade
Phone: 309-243-3605
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Gig Harbor, Washington 98335
Principal Investigator: John A. Keech
Phone: 253-403-2394
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Grand Rapids, Michigan 49503
Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
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100 Michigan St NE
Grand Rapids, Michigan 49503
(616) 391-1774
Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
Spectrum Health at Butterworth Campus Butterworth Hospital is one of four facilities that make up...
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Henderson, Nevada 89052
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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Houston, Texas 77030
Principal Investigator: Funda Meric-Bernstam
Phone: 713-792-3245
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Houston, TX
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800 W. Laurel
Independence, Kansas 67301
620-331-4099
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas-Independence Dr. H.E. Hynes founded Cancer Center of Kansas, P. A. in...
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Independence, KS
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Jefferson City, Missouri 65109
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Joplin, Missouri 64804
Principal Investigator: Jay W. Carlson
Phone: 417-556-3074
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1102 W 32nd St
Joplin, Missouri 64804
(417) 347-1111
Principal Investigator: Jay W. Carlson
Phone: 417-347-4030
Freeman Health System Freeman in Joplin, Missouri, is a 485-bed, three-hospital system providing comprehensive healthcare...
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1521 Gull Rd
Kalamazoo, Michigan 49048
269) 226-7000
Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
Borgess Medical Center At Borgess, healing is our calling. This is the place where people...
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205 Tenney St
Kewanee, Illinois 61443
309-852-0596
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Kewanee Clinic Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer...
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750 Avenue D West
Kingman, Kansas 67068
(620) 532-3147
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - Kingman Dr. H.E. Hynes founded Cancer Center of Kansas,...
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La Crosse, Wisconsin
Principal Investigator: Kurt Oettel
Phone: 608-775-2385
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Las Vegas, Nevada 89169
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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Las Vegas, Nevada 89109
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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Las Vegas, Nevada 89106
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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Las Vegas, Nevada 89149
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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Las Vegas, Nevada 89113
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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Las Vegas, Nevada 89128
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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Las Vegas, Nevada 89121
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
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9280 W. Sunset Road Suite 100
Las Vegas, Nevada 89148
702.952.1251
Principal Investigator: John A. Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada Comprehensive Cancer Centers of Nevada (CCCN) is the award-winning multidisciplinary...
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6190 South Fort Apache Road
Las Vegas, Nevada 89148
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325 Maine Street
Lawrence, Kansas 66044
(785) 505-5000
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Lawrence Memorial Hospital Lawrence Memorial Hospital (LMH), in collaboration with its medical staff, is dedicated...
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315 W. 15th St.
Liberal, Kansas 67905
(620) 629-6727
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - Liberal Dr. H.E. Hynes founded Cancer Center of Kansas,...
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Livonia, Michigan 48154
Principal Investigator: Philip J. Stella
Phone: 208-367-7954
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1441 Eastlake Ave
Los Angeles, California 90033
(323) 865-3000
Principal Investigator: Heinz-Josef Lenz
Phone: 323-865-0451
U.S.C./Norris Comprehensive Cancer Center The USC Norris Comprehensive Cancer Center, located in Los Angeles, is...
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Lynnwood, Washington 98036
Principal Investigator: John A. Keech
Phone: 253-403-2394
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501 E Grant
Macomb, Illinois 61455
309-833-3503
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Macomb Illinois CancerCare is one of the largest private oncology and hematology...
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Manhattan, Kansas 66502
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5784
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Marshfield, Wisconsin 54449
Principal Investigator: Adedayo A. Onitilo
Phone: 715-393-1400
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Memphis, Tennessee 38120
Principal Investigator: Raymond U. Osarogiagbon
Phone: 901-226-1366
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9601 Townline Rd
Minocqua, Wisconsin 54548
(715) 358-1000
Principal Investigator: Adedayo A. Onitilo
Phone: 715-393-1400
Marshfield Clinic Minocqua Center The Clinic was incorporated under Wisconsin law in 1916 and operates...
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1 Good Samaritan Way
Mount Vernon, Illinois 62864
(618) 242-4600
Principal Investigator: Jay W. Carlson
Phone: 618-242-4600
Good Samaritan Regional Health Center St. Mary's Good Samaritan, Incorporated (SMGSI) was created in 1996...
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Muskegon, Michigan 49444
Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
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New Haven, Connecticut 6520
(203) 432-4771
Principal Investigator: Patricia M. LoRusso
Phone: 203-785-5702
Yale University Yale's roots can be traced back to the 1640s, when colonial clergymen led...
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New Haven, Connecticut 06510
Principal Investigator: Patricia M. LoRusso
Phone: 203-785-5702
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New York, New York 10032
Principal Investigator: Matthew Ingham
Phone: 212-305-6361
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Newark, Delaware 19713
Principal Investigator: Gregory A. Masters
Phone: 302-733-6227
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Newark, Delaware 19713
Principal Investigator: Gregory A. Masters
Phone: 302-733-6227
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Newark, Delaware
Principal Investigator: Gregory A. Masters
Phone: 302-733-6227
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Newark, Delaware 19713
Principal Investigator: Gregory A. Masters
Phone: 302-733-6227
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4755 Ogletown-Stanton Road
Newark, Delaware 19718
302-733-1000
Principal Investigator: Gregory A. Masters
Phone: 302-733-6227
Christiana Care Health System - Christiana Hospital A 913-bed, 1.3-million-square-foot, modern facility in Newark, Delaware,...
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720 Medical Center Drive
Newton, Kansas 67114
(316) 282-0888
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - Newton Dr. H.E. Hynes founded Cancer Center of Kansas,...
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Niles, Michigan 49120
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Oklahoma City, Oklahoma 73120
Principal Investigator: Jay W. Carlson
Phone: 405-752-3402
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Ottawa, Illinois 61350
Principal Investigator: James L. Wade
Phone: 217-876-4740
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1200 Starfire Drive
Ottawa, Illinois 61350
815-431-9270
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare-Ottawa Clinic Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood diseases....
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1100 Belk Boulevard
Oxford, Mississippi 38655
Principal Investigator: Raymond U. Osarogiagbon
Phone: 901-226-1366
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1902 S. US Hwy 59
Parsons, Kansas 67357
(620) 421-2855
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - Parsons Dr. H.E. Hynes founded Cancer Center of Kansas,...
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603 S 13th St
Pekin, Illinois 61554
(309) 353-0214
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Pekin Illinois CancerCare is one of the largest private oncology and hematology...
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Pekin, Illinois 61554
Principal Investigator: James L. Wade
Phone: 309-243-3605
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221 NE Glen Oak Ave
Peoria, Illinois 61636
(309) 672-5522
Principal Investigator: James L. Wade
Phone: 309-243-3605
Methodist Medical Center of Illinois UnityPoint Health is one of the nation's most integrated health...
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Peoria, Illinois 61615
Principal Investigator: James L. Wade
Phone: 309-243-3605
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Peoria, Illinois 61637
Principal Investigator: James L. Wade
Phone: 309-243-3605
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8940 Wood Sage Rd
Peoria, Illinois 61615
(309) 243-3000
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare-Peoria Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood diseases. Our...
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4391 Venture Dr.
Peru, Illinois 61354
815-223-7010
Principal Investigator: James L. Wade
Phone: 309-243-3605
Illinois CancerCare - Peru Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood...
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Peru, Illinois 61354
Principal Investigator: James L. Wade
Phone: 309-243-3605
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124 Commodore, Ste. A
Pratt, Kansas 67124
(620) 672-2478
Principal Investigator: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas, PA - Pratt Dr. H.E. Hynes founded Cancer Center of Kansas,...
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