Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen



Status:Active, not recruiting
Conditions:Arthritis, Osteoarthritis (OA), Peripheral Vascular Disease, Rheumatoid Arthritis
Therapuetic Areas:Cardiology / Vascular Diseases, Rheumatology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:October 2006
End Date:March 2016

Use our guide to learn which trials are right for you!

A Randomized, Double Blind, Parallel-group Study Of Cardiovascular Safety In Osteoarthritis Or Rheumatoid Arthritis Patients With Or At High Risk For Cardiovascular Disease Comparing Celecoxib With Naproxen And Ibuprofen

To answer the question of overall benefit: risk of celecoxib when compared to two most
commonly prescribe traditional (non-selective) nonsteroidal anti-inflammatory drugs (NSAIDs)
in the treatment of arthritis pain. For this purpose, patients with osteoarthritis or
rheumatoid arthritis with or at risk of developing cardiovascular disease will be recruited.
The cardiovascular, gastrointestinal and renal safety and symptomatic benefit in each
treatment group will be assessed accordingly.


Inclusion Criteria:

- Subjects with osteoarthritis or rheumatoid Arthritis with or at risk of developing
cardiovascular disease and who require and eligible for chronic, daily therapy with
an NSAID to control arthritis sign and symptoms.

Exclusion Criteria:

- Subjects have had a recent cardiovascular event, unstable cardiovascular conditions,
or any major surgery (cardiac or non-cardiac) within 3 months prior to randomization;

- Subjects with medical or laboratory abnormality that would make the subject
inappropriate for entry into this trial

- Subjects require treatment with aspirin > 325 mg /day

- Subjects with known hypersensitivity to celecoxib, ibuprofen, naproxen, aspirin or
esomeprazole, etc.
We found this trial at
834
sites
Atlanta, Georgia 30309
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
2017 Canyon Road, Suite 41
Birmingham, Alabama 35216
(205) 757-8208
Site Overview Achieve has two clinical research sites in Birmingham, AL. Our Birmingham sites are conveniently located...
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
?
mi
from
DeLand, FL
Click here to add this to my saved trials
3635 S. Clyde Morris Blvd
Port Orange, Florida 32129
386-760-3862
About Us Accord Clinical Research is a privately owned research facility, founded in Port Orange,...
?
mi
from
Port Orange, FL
Click here to add this to my saved trials
148 E. Hersey St.
Ashland, Oregon 97520
541-488-9325
?
mi
from
Ashland, OR
Click here to add this to my saved trials
2147 Northeast Coachman Road
Clearwater, Florida 33765
?
mi
from
Clearwater, FL
Click here to add this to my saved trials
9500 Euclid Avenue
Cleveland, Ohio 44106
216.444.2200
Cleveland Clinic Cleveland Clinic is committed to principles as presented in the United Nations Global...
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
20 West Wenger Road
Englewood, Ohio 45322
937-771-5103
?
mi
from
Englewood, OH
Click here to add this to my saved trials
4110 Center Point Dr.
Fort Myers, Florida 33916
239-936-4421
?
mi
from
Fort Myers, FL
Click here to add this to my saved trials
Gainesville, Florida 32610
(352) 392-3261
University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
404 Memorial Dr.
Greer, South Carolina 29651
864-848-9293
?
mi
from
Greer, SC
Click here to add this to my saved trials
11701 San Jose Blvd # 32
Jacksonville, Florida 32223
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
750 Highland Avenue
Madison, Wisconsin 53792
?
mi
from
Madison, WI
Click here to add this to my saved trials
400 Tower Rd Ne
Marietta, Georgia 30060
678-581-5252
?
mi
from
Marietta, GA
Click here to add this to my saved trials
?
mi
from
Melbourne, FL
Click here to add this to my saved trials
342 Montauk Avenue
New London, Connecticut 06320
860-443-4567
?
mi
from
New London, CT
Click here to add this to my saved trials
6161 Kempsville Circle
Norfolk, Virginia 23502
(757) 261-4986
?
mi
from
Norfolk, VA
Click here to add this to my saved trials
100 West Gore St # 202
Orlando, Florida 32806
(407) 426-9299
Compass Research LLC Compass Research is a clinical research company dedicated to testing new medications...
?
mi
from
Orlando, FL
Click here to add this to my saved trials
Ste 205, 10796 Pines Boulevard
Pembroke Pines, Florida 33026
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
Pembroke Pines, Florida 33027
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
1148 E. Commerce St.
San Antonio, Texas 78205
(210) 340-5646
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
3212 Cove Bend Drive
Tampa, Florida 33613
?
mi
from
Tampa, FL
Click here to add this to my saved trials
6261 N. La Cholla Blvd
Tucson, Arizona 85741
520-219-6394
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
1897 Palm Beach Lakes Boulevard
West Palm Beach, Florida 33409
561-689-0606
?
mi
from
West Palm Beach, FL
Click here to add this to my saved trials
1709 S Rock Rd
Wichita, Kansas 67207
316-689-6629
?
mi
from
Wichita, KS
Click here to add this to my saved trials
Winter Park, Florida 32792
?
mi
from
Winter Park, FL
Click here to add this to my saved trials
Aberdeen, South Dakota 57401
?
mi
from
Aberdeen, SD
Click here to add this to my saved trials
?
mi
from
Akron, OH
Click here to add this to my saved trials
Alabaster, Alabama 35007
?
mi
from
Alabaster, AL
Click here to add this to my saved trials
Alliance, Nebraska 69301
?
mi
from
Alliance, NE
Click here to add this to my saved trials
Altoona, Pennsylvania 16601
?
mi
from
Altoona, PA
Click here to add this to my saved trials
Altoona, Pennsylvania 16602
?
mi
from
Altoona, PA
Click here to add this to my saved trials
Amarillo, Texas 79106
?
mi
from
Amarillo, TX
Click here to add this to my saved trials
Amarillo, Texas 79106
?
mi
from
Amarillo, TX
Click here to add this to my saved trials
Anaheim, California 92804
?
mi
from
Anaheim, CA
Click here to add this to my saved trials
Anaheim, California 92805
?
mi
from
Anaheim, CA
Click here to add this to my saved trials
Anderson, Indiana 46011
?
mi
from
Anderson, IN
Click here to add this to my saved trials
Anderson, South Carolina 29621
?
mi
from
Anderson, SC
Click here to add this to my saved trials
Anderson, South Carolina 29621
?
mi
from
Anderson, SC
Click here to add this to my saved trials
Arkansas City, Kansas 67005
?
mi
from
Arkansas City, KS
Click here to add this to my saved trials
Arlington, Texas 76013
?
mi
from
Arlington, TX
Click here to add this to my saved trials
?
mi
from
Arlington, TX
Click here to add this to my saved trials
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Artesia, California 90701
?
mi
from
Artesia, CA
Click here to add this to my saved trials
Arvada, Colorado 80005
?
mi
from
Arvada, CO
Click here to add this to my saved trials
Asheville, North Carolina 28803
?
mi
from
Asheville, NC
Click here to add this to my saved trials
Ashland, Kentucky 41101
?
mi
from
Ashland, KY
Click here to add this to my saved trials
Atlanta, Georgia 30308
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Atlanta, Georgia 30342
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Atlanta, Georgia 30342
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Atlantis, Florida 33462
?
mi
from
Atlantis, FL
Click here to add this to my saved trials
Auburn, Maine 04210
?
mi
from
Auburn, ME
Click here to add this to my saved trials
?
mi
from
Augusta, GA
Click here to add this to my saved trials
Augusta, Georgia 30909
?
mi
from
Augusta, GA
Click here to add this to my saved trials
Aurora, Colorado 80012
?
mi
from
Aurora, CO
Click here to add this to my saved trials
Aurora, Illinois 60504
?
mi
from
Aurora, IL
Click here to add this to my saved trials
?
mi
from
Austin, TX
Click here to add this to my saved trials
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
?
mi
from
Avon, IN
Click here to add this to my saved trials
Ayer, Massachusetts 01432
?
mi
from
Ayer, MA
Click here to add this to my saved trials
?
mi
from
Azusa, CA
Click here to add this to my saved trials
Babylon, New York 11702
?
mi
from
Babylon, NY
Click here to add this to my saved trials
Bainbridge, Georgia 39819
?
mi
from
Bainbridge, GA
Click here to add this to my saved trials
Baltimore, Maryland 21237
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baltimore, Maryland 21204
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baltimore, Maryland 21209
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baltimore, Maryland 21215
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baltimore, Maryland 21229
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baltimore, Maryland 21234
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baltimore, Maryland 21239
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Bay City, Michigan 48706
?
mi
from
Bay City, MI
Click here to add this to my saved trials
?
mi
from
Beaumont, TX
Click here to add this to my saved trials
?
mi
from
Beaumont, TX
Click here to add this to my saved trials
Beaver, Pennsylvania 15009
?
mi
from
Beaver, PA
Click here to add this to my saved trials
Beckley, West Virginia 25801
?
mi
from
Beckley, WV
Click here to add this to my saved trials
Bedford, Texas 76021
?
mi
from
Bedford, TX
Click here to add this to my saved trials
Bedford, Texas 76021
?
mi
from
Bedford, TX
Click here to add this to my saved trials
Bedford, Texas 76021
?
mi
from
Bedford, TX
Click here to add this to my saved trials
?
mi
from
Bel Air, MD
Click here to add this to my saved trials
Bell, California 90201
?
mi
from
Bell, CA
Click here to add this to my saved trials
Bellaire, Texas 77401
?
mi
from
Bellaire, TX
Click here to add this to my saved trials
?
mi
from
Bellevue, NE
Click here to add this to my saved trials
Benzonia, Michigan 49616
?
mi
from
Benzonia, MI
Click here to add this to my saved trials
Bessemer, Alabama 35022
?
mi
from
Bessemer, AL
Click here to add this to my saved trials
Bethlehem, Pennsylvania 18015
?
mi
from
Bethlehem, PA
Click here to add this to my saved trials
Biddeford, Maine 04005
?
mi
from
Biddeford, ME
Click here to add this to my saved trials
Biloxi, Mississippi 39531
?
mi
from
Biloxi, MS
Click here to add this to my saved trials
Birmingham, Alabama 35209
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Birmingham, Alabama 35235
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Birmingham, Alabama 35242
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Bloomingdale, Illinois 60108
?
mi
from
Bloomingdale, IL
Click here to add this to my saved trials
Boca Raton, Florida 33432
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
Boca Raton, Florida
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
Boise, Idaho 83702
?
mi
from
Boise, ID
Click here to add this to my saved trials
Boise, Idaho 83713
?
mi
from
Boise, ID
Click here to add this to my saved trials
Bossier City, Louisiana 71111
?
mi
from
Bossier City, LA
Click here to add this to my saved trials