Clinical Physiology Associates
4110 Center Point Dr.
Fort Myers, Florida 33916
239-936-4421 studycenter@clinphys.com

Use our guide to learn which trials are right for you!

Clinical Physiology Associates, a multispecialty research group, has been conducting clinical trials for the pharmaceutical and medical device industries for 29+ years. The use of central IRBs and laboratories are preferred. Turn around time for regulatory documents is less than 3 days. 

CPA Studies by discipline

Numbers within ( ) refer to the number of different medicines studied. Some medicines were studied in more than one protocol

Cardiology
  • Angina pectoris, chronic stable (30)
  • Congestive heart failure (9)
  • Hypertension (41)
  • Peripheral vascular disease (7)
  • Ventricular arrhythmias (4)
Central Nervous System
  • Alzheimer's disease (9)
  • Migraine headaches (5)
  • Seizure prophylaxis (4)
  • Stroke (ischemic) (1)
  • Tension headaches (1)
Dermatology
  • Psoriasis (1)
  • Tinea Cruris (1)
  • Tinea Pedis (1)
Endocrinology
  • Diabetes mellitus (7)
  • Diabetic neuropathy (15)
  • Obesity (2)
Gastroenterology
  • Acid Indigestion (1)
  • Constipation - opiate induced (1)
  • Gastroesophageal Reflux (chronic) (1)
  • Heart burn (1)
  • Irritable bowel syndrome' diarrhea predominant (4)
  • Irritable bowel syndrome' constipation predominant (1)
Genitourinary
  • Acute Urinary Retention (1)
  • Benign prostatic hyperplasia (11)
  • Bladder Cancer (superficial) (1)
  • Genital Herpes (3)
  • Hypogonadism [male] (1)
  • Impotence [erectile dysfunction] (15)
  • Impotence [erectile dysfunction] in spinal cord injury (1)
  • Impotence + dyslipidemia (1)
  • Nocturia (1)
  • Premature (rapid) ejaculation (1)
  • Premature (rapid) ejaculation + erectile dysfunction (1)
  • Prostate cancer (6)
  • Prostate Cancer Prevention (1)
  • Prostatitis (chronic) (2)
  • Sexual dysfunction (female) (6)
  • Sexual dysfunction (male & female) (1)
  • Urinary incontinence [urge, stress, mixed] (14)
  • Urinary tract infection [complicated, uncomplicated] (5)
Geriatrics
  • Chronic obstructive pulmonary disease (5)
  • Congestive heart failure (9)
  • Herpes zoster [shingles] (2)
  • Insomnia [elderly] (4)
  • Postherpetic neuralgia (9)
Gynecology
  • Contraception (2)
  • Osteopenia (1)
  • Osteoporosis (postmenopausal) (5)
  • Postmenopausal hormone replacement therapy (17)
  • Postmenopausal hormone substitute replacement therapy (1)
  • Premenstrual Dysphoric Disorder (PMDD) (2)
  • Premenstrual syndrome (PMS) (1)
  • Sexual dysfunction [women only] (6)
  • Sexual dysfunction [women & men] (1)
Internal medicine
  • Acid indigestion (1)
  • Angina pectoris (30)
  • Asthma (5)
  • Bronchitis (4)
  • Chronic obstructive pulmonary disease [COPD] (5)
  • Congestive heart failure [CHF] (9)
  • Constipation- opiate induced (2)
  • Diabetes mellitus (7)
  • Diabetic neuropathy (15)
  • Internal medicine, contd.
  • Diabetic neuropathic ulcers (2)
  • Gastroesophageal reflux (1)
  • Genital herpes (3)
  • Heartburn (1)
  • Hemorrhoids (1)
  • Herpes labialis (cold sores) (4)
  • Herpes zoster (shingles) (2)
  • Hypercholesterolemia (2)
  • Hypertension (41)
  • Hypertension + Osteoarthritis (1)
  • Infectious diseases [miscellaneous] (22)
  • Insomnia (2)
  • Insomnia [elderly] (4)
  • Irritable bowel syndrome (2)
  • Migraine headache (5)
  • Obesity (2)
  • Osteoarthritis (14)
  • Pain management (18)
  • Peripheral vascular disease (7)
  • Post- herpetic neuralgia (9)
  • Rheumatoid arthritis (1)
  • Sea sickness (1)
  • Skin & soft tissue infections (13)
  • Smoking cessation (1)
  • Tension headaches (1)
  • Urinary tract infections (5)
Miscellaneous
  • Sinusitis (2)
  • Venous Stasis Ulcers (2)
Neurology
  • Alzheimer's disease (9)
Oncology
  • Head & neck cancer (1)
  • Prostate cancer (8)
  • Prostate cancer prevention (1)
  • Prostatic intraepithelial neoplasia (PIN) (1)
  • Superficial bladder cancer (1)
Ophthalmology
  • Allergic conjunctivitis (1)
  • Bacterial Conjunctivitis (1)
  • Corneal Ulcer (1)
  • Ophthalmic Zoster (1)
Otolaryngology
  • Head & neck cancer (1)
  • Sinusitis (1)
Pharmacology
  • Hypogonadism (male) (1)
Surgery
  • Alzheimer's disease [neurosurgery] (1)
  • Decubitus ulcers [plastic & reconstructive surgery] (1)
  • Diabetic neuropathic ulcers [plastic & reconstructive surgery] (3)
  • Postoperative pain management [neurosurgery] (3)
  • Postoperative peridural fibrosis [neurosurgery] (2)
  • Scar revision [plastic & reconstructive surgery] (1)
  • Seizure prophylaxis [neurosurgery] (4)
  • Wound healing [plastic & reconstructive surgery] (2)

Pharmaceutical Companies worked with:

  • 3M Pharmaceuticals
  • A.H. Robins Company
  • Abbott Laboratories
  • Advanced Care Products
  • Aeterna
  • Alizyme Therapeutics, Ltd.
  • Allergan Pharmaceuticals
  • Alpha Therapeutic Corporation
  • Astellas
  • Astra Pharmaceuticals
  • AstraZeneca
  • Aventis
  • Barr
  • Bayer
  • Bayer Health Care
  • Berlex
  • Biosante
  • Boehringer Ingelheim Pharmaceuticals
  • Boehringer Mannheim Corporation
  • Bristol Myers Squibb Company
  • Burroughs Wellcome Company
  • Cellegy
  • Ciba Geigy Pharmaceutical Corporation
  • ConvaTec
  • Corcept
  • DepoMed
  • DuPont Pharmaceuticals
  • Duramed
  • Eisai
  • Eli Lilly and Company
  • Endo
  • Ethical Pharmaceuticals, Ltd.
  • Eunoe
  • Forest Research
  • FzioMed
  • Galen
  • G.D. Searle and Company
  • GlaxoSmithKline
  • Glaxo Welcome
  • Grunenthal
  • GTx, Inc.
  • Hisamitsu
  • Hoechst Roussel Pharmaceuticals
  • Hoffman LaRoche, Inc.
  • Human Geonome Science
  • IASO Pharma
  • ICI Pharmaceuticals
  • Indivus
  • International Medical Innovations
  • Interneuron Pharmaceuticals
  • Janssen Research Foundation
  • Johnson & Johnson
  • Key Pharm. Div. Schering Corp.
  • Kissei
  • Knoll
  • Labopharm
  • Lemmon Company
  • Lidak
  • Lilly
  • Lorex Pharmaceuticals
  • Lupin Ltd.
  • MacroChem
  • Magainin Pharmaceuticals, Inc.
  • Marion Merrell Dow Laboratories
  • Matrix
  • McNeil Consumer Products
  • McNeil Pharmaceutical
  • Merck
  • Miles Pharmaceuticals
  • Myriad
  • Neurobiological Technologies
  • Neurocrine Biosciences
  • NexMed
  • Nix-O-Tine Pharmaceuticals
  • NicOx SA
  • Novartis
  • Ono
  • Organon
  • Ortho- McNeil
  • Palatin Technologies
  • Parke-Davis
  • Pfizer (Groton)
  • Pfizer (New York)
  • Pharmacia
  • Pharmacia & Upjohn
  • Procter & Gamble
  • ProCyte Corporation
  • Radius Health
  • Reckett and Coleman
  • Reed and Carnrick
  • Revlon Health Care Group
  • Rhone Poulenc Rorer Pharmaceuticals
  • Roberts Pharmaceutical Corporation
  • Roche Bioscience
  • Roche Global Development
  • R.W. Johnson Pharm. Research Institute
  • Salix
  • Sandoz Pharmaceuticals
  • Sangamo
  • Sankyo U.S.A. Corp.
  • Sanofi Synthelabo
  • Schering Corporation
  • Schering Plough Research Institute
  • Schwarz Bioscience
  • Schwarz Pharma
  • Searle
  • Senju
  • Serono Laboratories, Inc.
  • SmithKline and French Laboratories
  • SmithKline Beecham Pharmaceuticals
  • Solvay
  • Sterling Winthrop
  • Stuart Pharmaceuticals
  • Sucampo
  • Sugen
  • Syntex Laboratories
  • Takeda America
  • Takeda Global
  • TAP Holdings
  • Tioga
  • Toyama
  • UCB Pharma
  • Unimed
  • Unither
  • Upjohn Company
  • Upsher Smith
  • USV Pharmaceutical Company
  • Vivus
  • W.F. Merchant Pharmaceutical Corporation
  • Wallace Laboratories
  • Wyeth Ayerst Laboratories
  • Wyeth Research
  • Xanodyne
  • XenoPort
  • Yamanouchi
  • Zeneca

Contract Research Organizations Worked With: 1978-Present

  • Barton & Polanski
  • Besselaar Associates
  • BioCLin
  • BioDecision Laboratories
  • BioPharm Clinical Services
  • Clinical Research Consultants
  • Clinical Research Group
  • Clinical Research Institute
  • Clinimetrics
  • Clinical Trial Management Services, Inc.
  • ClinTrials
  • Constella
  • Coromed
  • Covalent Research Alliance
  • Covance
  • Drug Research and Analysis Corporation
  • Health Decisions
  • i3 Research
  • IBRD
  • ICON Clinical Research
  • INC Research
  • Ingenix
  • Institute of Clinical Pharmacology
  • MDA Pharma
  • MDS Pharma Services
  • Medex
  • Medical and Technical Research Associates
  • Metropolitan Research Associates
  • Minnesota Clinical Study Center
  • Omnicare
  • Oxford Research International
  • PACT
  • Paragon Biomedical
  • Parexel
  • Pharmaco
  • Pharmaceutical Product Development
  • Pharmaceutical Resource Corp.
  • PharmaKinetics Laboratories, Inc.
  • PharmaNet
  • Phoenix International
  • PPD Development
  • PPD Pharmaco
  • Quintiles
  • Radiant Development
  • Resource Solutions
  • Scirex

David D. Michie, PhD.
Board Certified Sexology

Ronica Kluge, MD.
Board Certified Internal Medicine & Infectious Diseases

B. Koneru, MD.
Board Certified Internal Medicine & Oncology

Douglas Newland, MD. Certified Neurology

Mary Yankaskas, MD.
Board Certified Obstetrics & Gynecology

Harris Bonnette, MD.
Board Certified Neurology

Adam Heller, MD.
Board Certified Psychiatry & Neurology

Jack Clark, DO
Board Certified Rheumatology

The study center is staffed with full time study coordinators, coordinators' assistants and administrative personnel. All coordinators and their assistants are trained in shipping infectious & biological substances as per 49 CFR section 172,702 & IATA regulations. All staff members are trained in basic life support (CPR), HIPAA guidelines for clinical researchers and the protection of human research subjects.


Cardiology/Vascular Diseases
Immunology/Infectious Diseases
Musculoskeletal
Nephrology/Urology
Neurology
Obstetrics/Gynecology
Pharmacology/Toxicology
Pulmonary/Respiratory Diseases

  • Examination rooms (4)
  • Laboratory work areas (2)
  • Conference rooms [monitor work areas] (3)
  • Double locked limited access drug storage room with
    • Shelves
    • Counter tops
    • Refrigerator/ freezer
    • Steel locked controlled substance cabinet
  • Physician dictation area with X-ray view box
  • Computer room (on line data entry)
  • Coordinators' offices (5)
  • Administrative offices (3)
  • Spacious waiting room
  • Rest rooms (3)
SPECIALIZED SCIENTIFIC EQUIPMENT

Urology

  • Dantec Urodyn 1000 urine flowmeter (2)
  • Diagnostics Ultrasound Bladder Scan (2)
  • Rigiscan Plus (with computer interface)
  • Infusion Equipment (IMED Gemini PC-1) (2)

Cardiovascular

  • Parks Penilab V (non- invasive vascular lab)
  • Parks hand-held transcutaneous Doppler flowmeter
  • Parks photoplethysmograph and miscellaneous instruments to perform non-invasive assessments of the peripheral and penile circulations
  • Hokanson automatic cuff inflator
  • Nihon Kohden Cardiofax V [12 lead EKG] (2)
  • Novametrix transcutaneous oxygen monitor (2 channel)
  • Omron digital blood pressure monitor (3)
  • Quinton Exerdopâ„¢

Anthropometry

  • Harpenden Stadiometer

Gynecology

  • Vabra endometrial biopsy aspirator & related instruments

Pulmonary

  • KoKo Spirometer with computer interface

Laboratory (dry ice is available daily)

  • Refrigerator/ freezer -20 degrees Celsius (various)
  • Clinical centrifuges
  • Refrigerated centrifuge (Jouan CR412)
  • Test tube shaker
  • Leitz binocular optical microscope
  • Temp-Blok module heater
  • Corning Biotrack 516

Photographic

  • Yashica Dental-Eye II

Computers & Related Items

  • DSL line (all coordinators have internet access)
  • intra- office network
  • Computers: Dell
  • Facsimiles
    • Xerox WorkStation 390
    • Sharp FO-4500
    • HP 1010
  • Copy machines
    • Minolta DiALTA with sorter

Demographics of the area (July 2009 University of Florida BEBR)

  • Population estimate: 625,124
    • Persons 65+ years of age: 150,029
    • Females 18+ years of age: 255,050
  • Study Center Database: 7008
    • # female patients 4,563
    • # male patients 2,361
    • # of persons 65+ years of age: 2,245
    • # of male patients 65+ years of age: 1029
    • # of female patients +65 years of age: 1,197

Linda Aschom, President, ARNP
Dr. David Michie, Director of Research
Clinical Physiology Associates
4110 Center Point Dr., Suite 219
Ft. Myers, FL 33916
USA
239-936-4421
239-936-2865 (fax)
studycenter@clinphys.com
www.clinphys.com


We've found
6 trials
at this facility
Aging Frailty Clinical Trial
Phase IIb Trial to Evaluate Longeveron Mesenchymal Stem Cells to Treat Aging Frailty
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Fort Myers, FL
Click here to add this to my saved trials
Influenza A Clinical Trial
Study of Acute Uncomplicated Seasonal Influenza A in Adult Subjects
Status: Enrolling, Phase II
Updated: 7/28/2015
mi
from
Fort Myers, FL
Click here to add this to my saved trials
Atopic Dermatitis Clinical Trial
Phase 2B Study to Evaluate ASN002 in Subjects With Moderate to Severe Atopic Dermatitis (RADIANT)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Fort Myers, FL
Click here to add this to my saved trials
Human Papillomavirus Infections Clinical Trial
Safety, Reactogenicity and Immunogenicity of Adenovirus Serotype 26 (Ad26)- and Modified Vaccinia Ankara (MVA)-Vectored Vaccine Components in Otherwise Healthy Women With Persistent Human Papillomavirus HPV16 or HPV18 Infection of the Cervix
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Fort Myers, FL
Click here to add this to my saved trials
Aging Frailty Clinical Trial
Human Mesenchymal Stem Cells (LMSCs) on Vaccine-Specific Antibody- Response in Subjects With Aging Frailty
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Fort Myers, FL
Click here to add this to my saved trials
Atopic Dermatitis Clinical Trial
Study to Evaluate Long-Term Safety of ASN002 in Subjects With Moderate to Severe Atopic Dermatitis
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Fort Myers, FL
Click here to add this to my saved trials