Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia
Status: | Recruiting |
---|---|
Conditions: | Blood Cancer |
Therapuetic Areas: | Oncology |
Healthy: | No |
Age Range: | 15 - 39 |
Updated: | 2/24/2019 |
Start Date: | December 18, 2017 |
End Date: | September 30, 2021 |
Documentation and Delivery of Guideline-Consistent Treatment in Adolescent and Young Adult (AYA) Acute Lymphoblastic Leukemia (ALL)
This research trial studies cancer care delivery in adolescent and young adult patients with
acute lymphoblastic leukemia. Surveying institutions, evaluating delivery of care at the
patient level and seeking input from healthcare providers may help doctors increase rates of
adherence to National Comprehensive Cancer Network (NCCN) treatment guidelines. It may also
improve care for adolescent and young adult patients with acute lymphoblastic leukemia.
acute lymphoblastic leukemia. Surveying institutions, evaluating delivery of care at the
patient level and seeking input from healthcare providers may help doctors increase rates of
adherence to National Comprehensive Cancer Network (NCCN) treatment guidelines. It may also
improve care for adolescent and young adult patients with acute lymphoblastic leukemia.
PRIMARY OBJECTIVES:
I. To evaluate the proportion of adolescent and young adult (AYA) acute lymphoblastic
leukemia (ALL) patients with a documented treatment plan consistent with NCCN guidelines for
AYAs with ALL.
II. To evaluate the proportion of AYA ALL patients whose delivered treatment during induction
and post-induction therapy (PIT) is consistent with NCCN guidelines for AYAs with ALL.
III. To determine the impact of treating physician specialty and facility type on likelihood
of AYA ALL patients having a documented treatment plan concordant with NCCN guidelines when
stratified by age group (15-17year[y], 18-21y, and 22-39y).
IV. To determine the impact of treating physician specialty and facility type on the
likelihood of AYA ALL patients receiving induction and post-induction therapy (PIT)
concordant with NCCN guidelines when stratified by age group (15-17y, 18-21y, and 22-39y).
V. To identify for AYAs with ALL, targetable structure- and process-level barriers and
facilitators which will increase the proportion of patients having a documented treatment
plan and receiving treatment according to NCCN guidelines.
SECONDARY OBJECTIVES:
I. To explore potential correlations with clinical and social demographic variables to the
presence of a documented treatment plan and delivered treatment consistent with NCCN
guidelines in AYAs with ALL.
OUTLINE:
CHART REVIEW: Patient medical record data is abstracted and treatment plans are reviewed for
consistency to NCCN guidelines. For each patient, induction and post-induction care is
recorded as either concordant with NCCN guidelines or non-concordant with NCCN guidelines.
SITE QUESTIONNAIRE: Participating sites complete a questionnaire which is designed to capture
facility-oriented data.
FOCUS GROUPS: Healthcare providers participate in focus groups over 1-2 hours to discuss
facilitators and barriers to AYA ALL guideline concordance. Participants provide responses
via electronic handheld technology in order to maintain anonymity followed by discussion of
the ideas for clarification.
I. To evaluate the proportion of adolescent and young adult (AYA) acute lymphoblastic
leukemia (ALL) patients with a documented treatment plan consistent with NCCN guidelines for
AYAs with ALL.
II. To evaluate the proportion of AYA ALL patients whose delivered treatment during induction
and post-induction therapy (PIT) is consistent with NCCN guidelines for AYAs with ALL.
III. To determine the impact of treating physician specialty and facility type on likelihood
of AYA ALL patients having a documented treatment plan concordant with NCCN guidelines when
stratified by age group (15-17year[y], 18-21y, and 22-39y).
IV. To determine the impact of treating physician specialty and facility type on the
likelihood of AYA ALL patients receiving induction and post-induction therapy (PIT)
concordant with NCCN guidelines when stratified by age group (15-17y, 18-21y, and 22-39y).
V. To identify for AYAs with ALL, targetable structure- and process-level barriers and
facilitators which will increase the proportion of patients having a documented treatment
plan and receiving treatment according to NCCN guidelines.
SECONDARY OBJECTIVES:
I. To explore potential correlations with clinical and social demographic variables to the
presence of a documented treatment plan and delivered treatment consistent with NCCN
guidelines in AYAs with ALL.
OUTLINE:
CHART REVIEW: Patient medical record data is abstracted and treatment plans are reviewed for
consistency to NCCN guidelines. For each patient, induction and post-induction care is
recorded as either concordant with NCCN guidelines or non-concordant with NCCN guidelines.
SITE QUESTIONNAIRE: Participating sites complete a questionnaire which is designed to capture
facility-oriented data.
FOCUS GROUPS: Healthcare providers participate in focus groups over 1-2 hours to discuss
facilitators and barriers to AYA ALL guideline concordance. Participants provide responses
via electronic handheld technology in order to maintain anonymity followed by discussion of
the ideas for clarification.
Inclusion Criteria:
- Newly diagnosed with either Ph- or Ph+ ALL between January 1st, 2012 and December
31st, 2016
- Both diagnosed and initially treated at the participating National Cancer Institute
Community Oncology Research Program (NCORP) institution during induction and
post-induction therapy (PIT)
- Aim 3: Healthcare professional currently employed at a participating NCORP institution
- Eligible healthcare providers include but are not limited to: physicians,
registered nurses (RNs), nurse practitioners, physician assistants, patient
advocates, social workers, pharmacists and clinical research associates (CRAs)
- Aim 3a: Direct involvement in the care of AYA ALL patients
Exclusion Criteria:
- Diagnosis of secondary ALL
- Diagnosis of mixed lineage acute leukemia
- Diagnosis of acute leukemia of ambiguous lineage (ALAL)
- Diagnosis of Burkitt?s leukemia
- Transfer of care to another institution during induction or post-induction therapy
(PIT)
- Aim 3: Trainee
We found this trial at
444
sites
La Crosse, Wisconsin
Principal Investigator: Collin D. Driscoll
Phone: 608-775-2385
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1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
Albuquerque, New Mexico 87131
(505) 272-4946

Principal Investigator: John F. Kuttesch
Phone: 505-925-0366
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
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4900 Mueller Boulevard
Austin, Texas 78723
Austin, Texas 78723
(512) 324-0000

Principal Investigator: Amy C. Fowler
Dell Children's Medical Center of Central Texas Welcome to Dell Children
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2545 Schoenersville Rd
Bethlehem, Pennsylvania 18017
Bethlehem, Pennsylvania 18017
(484) 884-2200

Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
Lehigh Valley Hospital - Muhlenberg At Lehigh Valley Health Network, we continually go the extra...
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Bremerton, Washington 98310
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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3533 South Alameda Street
Corpus Christi, Texas 78411
Corpus Christi, Texas 78411
(361) 694-5000

Principal Investigator: Nkechi I. Mba
Driscoll Children's Hospital Driscoll Children's Hospital was built because Clara Driscoll's will requested that a...
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1200 Pleasant Street
Des Moines, Iowa 50309
Des Moines, Iowa 50309
(515) 241-KIDS

Principal Investigator: Wendy L. Woods-Swafford
Blank Children's Hospital Blank Children's Hospital is completely dedicated to meeting the unique health care...
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1 Hurley Plaza
Flint, Michigan 48503
Flint, Michigan 48503
(810) 262-9000

Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
Hurley Medical Center From its founding in 1908, Hurley Medical Center has devoted itself to...
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100 Michigan Street Northeast
Grand Rapids, Michigan 49503
Grand Rapids, Michigan 49503
616.391.9000

Principal Investigator: Kathleen J. Yost
Helen DeVos Children's Hospital at Spectrum Health Helen DeVos Children's Hospital, located in Grand Rapids,...
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524 South Park Street
Kalamazoo, Michigan 49007
Kalamazoo, Michigan 49007
(269) 341-7654

Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
Bronson Methodist Hospital Our healthcare system serves patients and families throughout southwest Michigan and northern...
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200 North Park Street
Kalamazoo, Michigan 49007
Kalamazoo, Michigan 49007
(269) 382-2500

Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
West Michigan Cancer Center In 1994, Borgess Health Alliance and Bronson Healthcare Group opened the...
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1800 West Charleston Boulevard
Las Vegas, Nevada 89102
Las Vegas, Nevada 89102
(702) 383-2000

Principal Investigator: Alan K. Ikeda
Phone: 702-384-0013
University Medical Center of Southern Nevada University Medical Center is dedicated to providing the highest...
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747 52nd St
Oakland, California 94609
Oakland, California 94609
(510) 428-3000

Principal Investigator: Carla B. Golden
Children's Hospital and Research Center Oakland For nearly 100 years, Children's Hospital & Research Center...
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4805 Northeast Glisan Street
Portland, Oregon 97213
Portland, Oregon 97213
(503) 215-1111

Principal Investigator: Benjamin B. Bridges
Phone: 503-215-2614
Providence Portland Medical Center We strive to give those we serve exceptional, compassionate health care...
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4502 Medical Drive
San Antonio, Texas 78284
San Antonio, Texas 78284
(210) 567-7000

Principal Investigator: Anne-Marie R. Langevin
Phone: 210-450-3800
University of Texas Health Science Center at San Antonio The University of Texas Health Science...
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7700 Floyd Curl Dr
San Antonio, Texas 78229
San Antonio, Texas 78229
(210) 575-7000

Principal Investigator: Vinod K. Gidvani-Diaz
Methodist Children's Hospital of South Texas Methodist Children
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Seattle, Washington 98104
Principal Investigator: Benjamin B. Bridges
Phone: 206-215-3086
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1600 Rockland Road
Wilmington, Delaware 19803
Wilmington, Delaware 19803
(302) 651-4200

Principal Investigator: Scott M. Bradfield
Phone: 302-651-6884
Alfred I. duPont Hospital for Children Nemours began more than 70 years ago with the...
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98-1079 Moanalua Road
'Aiea, Hawaii 96701
'Aiea, Hawaii 96701
Principal Investigator: Jeffrey L. Berenberg
Phone: 808-486-6000
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'Aiea, Hawaii 96701
Principal Investigator: Jeffrey L. Berenberg
Phone: 808-487-7447
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2226 Liliha Street
'Aiea, Hawaii 96701
'Aiea, Hawaii 96701
Principal Investigator: Wade T. Kyono
Phone: 808-678-9000
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'Aiea, Hawaii 96701
Principal Investigator: Jeffrey L. Berenberg
Phone: 808-539-2273
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Aberdeen, Washington 98520
Principal Investigator: Benjamin B. Bridges
Phone: 360-412-8958
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Allentown, Pennsylvania 18103
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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Anaheim, California 92806
Principal Investigator: Erin E. Hahn
Phone: 800-398-3996
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Anchorage, Alaska 99508
Principal Investigator: Benjamin B. Bridges
Phone: 907-212-6871
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Anchorage, Alaska 99508
Principal Investigator: Benjamin B. Bridges
Phone: 907-212-6871
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Anchorage, Alaska 99508
Principal Investigator: Benjamin B. Bridges
Phone: 907-212-6871
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Anchorage, Alaska 99508
Principal Investigator: Benjamin B. Bridges
Phone: 907-212-6871
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Anchorage, Alaska 99508
Principal Investigator: Benjamin B. Bridges
Phone: 907-212-6871
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Anchorage, Alaska 99508
Principal Investigator: Benjamin B. Bridges
Phone: 888-823-5923
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Anchorage, Alaska 98508
Principal Investigator: Benjamin B. Bridges
Phone: 907-212-6871
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5301 McAuley Drive
Ann Arbor, Michigan 48197
Ann Arbor, Michigan 48197
734-712-3456

Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
Saint Joseph Mercy Hospital St. Joseph Mercy Ann Arbor Hospital is a 537-bed teaching hospital...
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Antioch, California 94531
Principal Investigator: Samantha A. Seaward
Phone: 877-642-4691
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921 North Oak Park Boulevard
Arroyo Grande, California 93420
Arroyo Grande, California 93420
Principal Investigator: Alan K. Ikeda
Phone: 702-384-0013
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1625 Maple Lane
Ashland, Wisconsin 54806
Ashland, Wisconsin 54806
Principal Investigator: Andrea M. Watson
Phone: 218-786-3308
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Ashland, Wisconsin 54806
Principal Investigator: Andrea M. Watson
Phone: 218-786-3308
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1000 Johnson Ferry Rd NE
Atlanta, Georgia 30342
Atlanta, Georgia 30342
(404) 851-8000

Principal Investigator: Guilherme Henrique C. Cantuaria
Phone: 404-303-3355
Northside Hospital Northside Hospital-Atlanta (in Sandy Springs) opened in 1970. The original facility had 250...
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Augusta, Georgia 30912
Principal Investigator: Colleen H. McDonough
Phone: 706-721-2388
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Aurora, Colorado 80012
Principal Investigator: Keren Sturtz
Phone: 303-777-2663
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1501 S Potomac St
Aurora, Colorado 80012
Aurora, Colorado 80012
(303) 695-2600

Principal Investigator: Keren Sturtz
Phone: 303-777-2663
Medical Center of Aurora At The Medical Center of Aurora and Centennial Medical Plaza patients...
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Baldwin Park, California 91706
Principal Investigator: Erin E. Hahn
Phone: 800-398-3996
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4305 New Shepherdsville Road
Bardstown, Kentucky 40004
Bardstown, Kentucky 40004
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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265 Fremont St
Battle Creek, Michigan 49017
Battle Creek, Michigan 49017
(269) 245-8166

Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
Bronson Battle Creek As a proud member of the Battle Creek community, we believe everyone...
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Bellflower, California 90706
Principal Investigator: Erin E. Hahn
Phone: 800-398-3996
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Bellingham, Washington 98225
Principal Investigator: Benjamin B. Bridges
Phone: 360-715-4133
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Bend, Oregon 97701
Principal Investigator: Benjamin B. Bridges
Phone: 541-706-2909
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1233 North 30th Street
Billings, Montana 59101
Billings, Montana 59101
406-237-7000

Principal Investigator: Keren Sturtz
Phone: 406-969-6060
Saint Vincent Healthcare The Sisters of Charity of Leavenworth, Kansas, founded St. Vincent Healthcare in...
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Billings, Montana 59102
Principal Investigator: Keren Sturtz
Phone: 800-648-6274
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1505 Eastland Drive
Bloomington, Illinois 61701
Bloomington, Illinois 61701
309-662-2102

Principal Investigator: Bryan A. Faller
Phone: 309-243-3605
Illinois CancerCare-Bloomington Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood diseases. Our...
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100 E Idaho St
Boise, Idaho 83712
Boise, Idaho 83712
(208) 381-2711

Principal Investigator: Benjamin B. Bridges
Saint Luke's Mountain States Tumor Institute For more than 100 years, St. Luke
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Bonne Terre, Missouri 63628
Principal Investigator: Bryan A. Faller
Phone: 314-996-5569
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1100 Balsam Ave
Boulder, Colorado 80304
Boulder, Colorado 80304
(303) 440-2273

Principal Investigator: Keren Sturtz
Phone: 303-777-2663
Boulder Community Hospital Founded in 1922 as a community-owned and operated not-for-profit hospital, Boulder Community...
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Boulder, Colorado 80303
Principal Investigator: Keren Sturtz
Phone: 303-777-2663
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Brainerd, Minnesota 56401
Principal Investigator: Andrea M. Watson
Phone: 888-823-5923
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Bremerton, Washington 98310
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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7575 Grand River Avenue
Brighton, Michigan 48114
Brighton, Michigan 48114
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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7575 Grand River Avenue
Brighton, Michigan 48114
Brighton, Michigan 48114
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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Bronx, New York 10467
Principal Investigator: Lisa Gennarini
Phone: 888-823-5923
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Bronx, New York 10467
Principal Investigator: Lisa Gennarini
Phone: 718-379-6866
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Bronx, New York 10461
Principal Investigator: Lisa Gennarini
Phone: 718-379-6866
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Bronx, New York 10461
Principal Investigator: Lisa Gennarini
Phone: 718-379-6866
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Bryan, Texas 77802
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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130 S Bryn Mawr Ave
Bryn Mawr, Pennsylvania 19010
Bryn Mawr, Pennsylvania 19010
(484) 337-3000

Principal Investigator: Albert S. DeNittis
Phone: 484-476-2649
Bryn Mawr Hospital Bryn Mawr Hospital, a nationally recognized community teaching hospital, is conveniently located...
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Burbank, California
Principal Investigator: Benjamin B. Bridges
Phone: 818-847-4793
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Burien, Washington 98166
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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201 E Nicollet Blvd
Burnsville, Minnesota 55337
Burnsville, Minnesota 55337
(952) 892-2000

Principal Investigator: Pamala A. Pawloski
Phone: 952-993-1517
Fairview Ridges Hospital Fairview Ridges Hospital is a 150-bed, Level III Trauma Care facility, offering...
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400 South Clark Street
Butte, Montana 59701
Butte, Montana 59701
406-723-2500

Principal Investigator: Keren Sturtz
Phone: 406-723-2621
Saint James Community Hospital and Cancer Treatment Center St. James Healthcare has played an important...
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210 W Walnut St
Canton, Illinois 61520
Canton, Illinois 61520
309-647-5240

Principal Investigator: Bryan A. Faller
Phone: 309-243-3605
Illinois CancerCare - Canton Illinois CancerCare is one of the largest private oncology and hematology...
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1600 South Canton Center Road
Canton, Michigan 48188
Canton, Michigan 48188
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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1600 South Canton Center Road
Canton, Michigan 48188
Canton, Michigan 48188
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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211 Saint Francis Drive
Cape Girardeau, Missouri 63703
Cape Girardeau, Missouri 63703
573-331-3000

Principal Investigator: Bryan A. Faller
Phone: 573-334-2230
Saint Francis Medical Center Saint Francis Medical Center is a 282-bed facility serving more than...
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789 Mt Auburn Rd
Cape Girardeau, Missouri 63703
Cape Girardeau, Missouri 63703
(573) 519-4725

Principal Investigator: Bryan A. Faller
Phone: 573-651-5550
Southeast Cancer Center SoutheastHEALTH is a far-reaching network of providers and facilities including Southeast Hospital...
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Carbondale, Illinois 62902
Principal Investigator: Bryan A. Faller
Phone: 618-457-5200
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401 North Hooper Street
Caro, Michigan 48723
Caro, Michigan 48723
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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Carson City, Nevada 89703
Principal Investigator: Alan K. Ikeda
Phone: 702-384-0013
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Carterville, Illinois 62918
Principal Investigator: Bryan A. Faller
Phone: 618-985-3333
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160 S Adams St
Carthage, Illinois 62321
Carthage, Illinois 62321
(217) 357-6877

Principal Investigator: Bryan A. Faller
Phone: 309-243-3605
Illinois CancerCare - Carthage Illinois CancerCare, P.C. is a comprehensive practice treating patients withcancer andblood...
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Centralia, Illinois 62801
Principal Investigator: Bryan A. Faller
Phone: 217-876-4740
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Centralia, Washington 98531
Principal Investigator: Benjamin B. Bridges
Phone: 360-412-8958
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Chadds Ford, Pennsylvania 19317
Principal Investigator: Gregory A. Masters
Phone: 302-623-4450
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Chattanooga, Tennessee 37404
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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775 South Main Street
Chelsea, Michigan 48118
Chelsea, Michigan 48118
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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14650 East Old US Highway 12
Chelsea, Michigan 48118
Chelsea, Michigan 48118
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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Cheyenne, Wyoming 82001
Principal Investigator: Keren Sturtz
Phone: 303-777-2663
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1969 W Ogden Ave
Chicago, Illinois 60612
Chicago, Illinois 60612
(312) 864-6000

Principal Investigator: Thomas E. Lad
Phone: 312-864-5204
John H. Stroger, Jr. Hospital of Cook County The Level 1 Trauma Center is one...
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Cincinnati, Ohio 45242
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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Cincinnati, Ohio 45220
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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Cincinnati, Ohio 45255
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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Cincinnati, Ohio 45247
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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9280 SE Sunnybrook Blvd #100
Clackamas, Oregon 97015
Clackamas, Oregon 97015
(503) 513-3300

Principal Investigator: Benjamin B. Bridges
Phone: 503-215-2614
Clackamas Radiation Oncology Center State-of-the-art technology and compassionate care come together at Clackamas Radiation Oncology...
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Clackamas, Oregon 97015
Principal Investigator: Benjamin B. Bridges
Phone: 503-215-2614
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5680 Bow Pointe Drive
Clarkston, Michigan 48346
Clarkston, Michigan 48346
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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31500 Telegraph Road
Clarkston, Michigan 48346
Clarkston, Michigan 48346
Principal Investigator: Tareq Al Baghdadi
Phone: 734-712-3671
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12495 University Ave
Clive, Iowa 50325
Clive, Iowa 50325
(515) 358-9700

Principal Investigator: Richard L. Deming
Phone: 308-398-6518
Mercy Cancer Center - West Lakes When it comes to cancer care, there
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Clive, Iowa 50325
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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6001 E Woodmen Rd
Colorado Springs, Colorado 80923
Colorado Springs, Colorado 80923
(719) 776-5000
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
Penrose-Saint Francis Healthcare Founded by the Sisters of St. Francis and the Sisters of Charity,...
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Colorado Springs, Colorado 80907
Principal Investigator: Richard L. Deming
Phone: 308-398-6518
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