A Study of the Safety and Effectiveness of DDP733 in Treating IBS With Constipation in Females



Status:Recruiting
Conditions:Constipation, Irritable Bowel Syndrome (IBS)
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 65
Updated:4/2/2016
Start Date:October 2007

Use our guide to learn which trials are right for you!

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Effectiveness of DDP733 in Female Patients With Irritable Bowel Syndrome With Constipation

This study will evaluate the safety and effectiveness of the investigational drug DDP733 in
treating female patients with IBS-c. A placebo control will be utilized.


Inclusion Criteria:

- Female from 18 to 65 years of age, inclusive

- Patient experiences recurrent abdominal pain or discomfort at least 3 days per month
for the last 3 months with symptom onset at least 6 months prior to diagnosis. The
patient's symptoms must be associated with 1 or more of the following:

- Improvement with defecation

- Onset associated with a change in frequency of stool

- Onset associated with a change in form (appearance) of stool

- Negative serum and urine pregnancy tests

- Completion of at least six days of daily diary assessments using a phone-in
information system prior to randomization

Exclusion Criteria:

- Serious underlying diseases, including psychiatric disorders

- Current history of conditions affecting bowel transit

- Recent history of biochemical or structural abnormalities of the gastrointestinal
tract, gastrointestinal surgery, or gastrointestinal infection

- Clinically significant abnormal examination findings or laboratory tests

- Inability to stop taking certain medications, or a planned change in medications
(including herbal remedies) which could interfere with study assessments

- Use of drugs and or ethanol which may interfere with compliance of study procedures
or influence study outcome

- Presence of a medical condition which could interfere with the interpretation of
study data

- Significant use of nicotine or caffeine
We found this trial at
62
sites
135 W. Ravine Road
Kingsport, Tennessee 37660
423-230-3154
?
mi
from
Kingsport, TN
Click here to add this to my saved trials
3635 S. Clyde Morris Blvd
Port Orange, Florida 32129
386-760-3862
About Us Accord Clinical Research is a privately owned research facility, founded in Port Orange,...
?
mi
from
Port Orange, FL
Click here to add this to my saved trials
5458 Town Center Rd # 19
Boca Raton, Florida 33486
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
303 Williams Ave
Huntsville, Alabama 35801
256-533-6603
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
875 Military Trl # 210
Jupiter, Florida 33458
?
mi
from
Jupiter, FL
Click here to add this to my saved trials
6850 Coral Way # 409
Miami, Florida 33155
?
mi
from
Miami, FL
Click here to add this to my saved trials
401 Roxbury Road
Rockford, Illinois 61107
815-397-7340
?
mi
from
Rockford, IL
Click here to add this to my saved trials
3212 Cove Bend Drive
Tampa, Florida 33613
?
mi
from
Tampa, FL
Click here to add this to my saved trials
6261 N. La Cholla Blvd
Tucson, Arizona 85741
520-219-6394
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
1709 S Rock Rd
Wichita, Kansas 67207
316-689-6629
?
mi
from
Wichita, KS
Click here to add this to my saved trials
Atlanta, Georgia 30328
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Beverly Hills, California 90211
?
mi
from
Beverly Hills, CA
Click here to add this to my saved trials
Birmingham, Alabama 35215
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Boston, Massachusetts 02135
?
mi
from
Boston, MA
Click here to add this to my saved trials
Brooklyn, New York 11214
?
mi
from
Brooklyn, NY
Click here to add this to my saved trials
Castle Rock, Colorado 80108
?
mi
from
Castle Rock, CO
Click here to add this to my saved trials
Chapel Hill, North Carolina 27514
?
mi
from
Chapel Hill, NC
Click here to add this to my saved trials
Chattanooga, Tennessee 37403
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
?
mi
from
Chevy Chase, MD
Click here to add this to my saved trials
Cincinnati, Ohio 45224
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Cleveland, Ohio 44122
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
?
mi
from
Dayton, OH
Click here to add this to my saved trials
ELkhart, Indiana 46514
?
mi
from
ELkhart, IN
Click here to add this to my saved trials
Encinitas, California 92024
?
mi
from
Encinitas, CA
Click here to add this to my saved trials
Evansville, Indiana 47714
?
mi
from
Evansville, IN
Click here to add this to my saved trials
Foothill Ranch, California 92610
?
mi
from
Foothill Ranch, CA
Click here to add this to my saved trials
?
mi
from
Garden Grove, CA
Click here to add this to my saved trials
Henderson, Nevada 89014
?
mi
from
Henderson, NV
Click here to add this to my saved trials
High Point, North Carolina 27262
?
mi
from
High Point, NC
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials
Huntsville, Alabama 35801
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
Idaho Falls, Idaho 83404
?
mi
from
Idaho Falls, ID
Click here to add this to my saved trials
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Jackson, Mississippi 39202
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Jackson, Tennessee 38301
?
mi
from
Jackson, TN
Click here to add this to my saved trials
Jackson, Tennessee 38305
?
mi
from
Jackson, TN
Click here to add this to my saved trials
3901 Rainbow Blvd
Kansas City, Kansas 66160
(913) 588-5000
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
?
mi
from
Laurel, MD
Click here to add this to my saved trials
Longview, Texas 75605
?
mi
from
Longview, TX
Click here to add this to my saved trials
?
mi
from
Marietta, GA
Click here to add this to my saved trials
Mexico City, Missouri 65265
?
mi
from
Mexico City, MO
Click here to add this to my saved trials
?
mi
from
Milwaukee, WI
Click here to add this to my saved trials
Mission Vejo, California 92691
?
mi
from
Mission Vejo, CA
Click here to add this to my saved trials
Mobile, Alabama 36617
?
mi
from
Mobile, AL
Click here to add this to my saved trials
Ogden, Utah 84405
?
mi
from
Ogden, UT
Click here to add this to my saved trials
Paw Paw, Michigan 49079
?
mi
from
Paw Paw, MI
Click here to add this to my saved trials
Peoria, Arizona 85381
?
mi
from
Peoria, AZ
Click here to add this to my saved trials
Peoria, Illinois 61602
?
mi
from
Peoria, IL
Click here to add this to my saved trials
Pittsburgh, Pennsylvania 15206
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
3100 Duraleigh Rd
Raleigh, North Carolina 27612
(919) 781-2514
Wake Research Associates, LLC Wake Research is an Organization of Unified Investigational Sites working closely...
?
mi
from
Raleigh, NC
Click here to add this to my saved trials
San Diego, California 92103
?
mi
from
San Diego, CA
Click here to add this to my saved trials
San Diego, California 92108
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Seattle, Washington 98101
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Sherwood, Arkansas 72120
?
mi
from
Sherwood, AR
Click here to add this to my saved trials
Shreveport, Louisiana 71103
?
mi
from
Shreveport, LA
Click here to add this to my saved trials
Spokane, Washington 99207
?
mi
from
Spokane, WA
Click here to add this to my saved trials
Spokane, Washington 99216
?
mi
from
Spokane, WA
Click here to add this to my saved trials
Waukesha, Wisconsin 53186
?
mi
from
Waukesha, WI
Click here to add this to my saved trials
Westlake Village, California 91361
?
mi
from
Westlake Village, CA
Click here to add this to my saved trials
Winston-Salem, North Carolina 27103
?
mi
from
Winston-Salem, NC
Click here to add this to my saved trials
Woodstock, Georgia 30189
?
mi
from
Woodstock, GA
Click here to add this to my saved trials