Amyotrophic Lateral Sclerosis (ALS) Clinical Trials

Clinical research team working with ALS patientsAt this time, there are no effective treatments available to slow or stop amyotrophic lateral sclerosis (ALS), so many people who are diagnosed with this illness choose to enroll in an ALS clinical trial. Clinical Trials GPS provides updated and unbiased information on ALS clinical trials taking place around the country. Currently, stem cell therapy has shown promise as a treatment for ALS in phase I clinical trials.

By choosing to participate in an ALS clinical study, you may be gaining access to experimental treatments or therapies that are not yet available to anyone else. That being said, these treatments are still in the testing phases which means there is no guarantee that they’ll help your condition. If you have exhausted the available treatment options for ALS, then participating in a clinical trial can be a viable option worth considering.

What is ALS?

ALS, also known as Lou Gehrig’s disease, is an illness that causes the nerve cells in the brain and spinal cord to die off slowly. These specific nerve cells are known as motor neurons, and they are in control of the muscles that allow human beings to move the different parts of their body. As the disease progresses, patients become increasingly more disabled.

The rate of progression for ALS varies from patient to patient, with some people able to live for several years after its onset. Inevitably, Lou Gehrig’s disease will make it very hard to walk, eat, speak, swallow, or even breathe. The symptoms of ALS make the patient much more susceptible to illness, injury, and eventually death. For most patients, death will occur within 3 to 5 years following the onset of their symptoms. However, some people have managed to live for decades with ALS.

ALS Treatment

As it stands, there is still no effective method of reversing the progression of ALS. Conventional treatments and therapies are primarily focused on slowing disease progression down as much as possible while also ensuring that the patient can be as comfortable and independent as possible.

Supportive care for ALS patients should be provided by a multidisciplinary team of health care experts including pharmacists, physicians, nutritionists, physical, speech, and occupational therapists, as well as home care and hospice nurses. By working with their patient, this team can develop a personalized treatment plan that effectively incorporates both medical and physical therapy with specialized equipment.

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We've found
67 ALS
clinical trials

Neurology, Psychiatry / Psychology, Other Clinical Trial
Wisconsin Brain Donor Program
Status: Enrolling
Updated: 3/30/2017
mi
from
Madison, WI
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Neurology, Orthopedics / Podiatry, Other Clinical Trial
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Status: Enrolling
Updated: 6/2/2016
mi
from
Pittsburgh, PA
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
DNA, Blood and Skin Cell Repository for Research on ALS and Related Neurodegenerative Disorders at Mayo Clinic Florida
Status: Enrolling, Phase
Updated: 3/20/2018
mi
from
Jacksonville, FL
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Neurology, Other Clinical Trial
Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Baltimore, MD
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
San Francisco, CA
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Phoenix, AZ
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Pittsburgh, PA
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Rochester, MN
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Houston, TX
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Pittsburgh, PA
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ALS Clinical Trial
Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Kansas City, KS
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Neurology, Orthopedics / Podiatry, Other Clinical Trial
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Status: Enrolling
Updated: 6/2/2016
mi
from
Jacksonville, FL
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Imaging and BioFluid Biomarkers in Amyotrophic Lateral Sclerosis
Status: Enrolling, Phase
Updated: 3/21/2018
mi
from
Houston, TX
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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Neurology, Other Clinical Trial
Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)
Status: Enrolling, Phase II
Updated: 1/26/2018
mi
from
Rochester, MN
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Worcester, MA
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Salt Lake City, UT
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Portland, OR
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Neurology, Other Clinical Trial
Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease
Status: Enrolling
Updated: 12/31/1969
mi
from
Gainesville, FL
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ALS Clinical Trial
Amyotrophic Lateral Sclerosis (ALS) Families Project
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Charlestown, MA
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Dallas, TX
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Jacksonville, FL
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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Neurology, Other Clinical Trial
Speech Analysis in ALS Patients
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Phoenix, AZ
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Los Angeles, CA
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Birmingham, AL
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Rochester, MN
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Saint Louis, MO
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Grand Rapids, MI
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Los Angeles, CA
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Minneapolis, MN
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Ann Arbor, MI
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Aurora, CO
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Saint Louis, MO
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Neurology, Other Clinical Trial
ECoG BMI for Motor and Speech Control
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
San Francisco, CA
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Neurology, Other Clinical Trial
Genetics of Familial and Sporadic ALS
Status: Enrolling, Phase
Updated: 3/27/2018
mi
from
Chicago, IL
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Neurology, Orthopedics / Podiatry, Other Clinical Trial
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Status: Enrolling
Updated: 6/2/2016
mi
from
Atlanta, GA
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Neurology, Orthopedics / Podiatry, Other Clinical Trial
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Status: Enrolling
Updated: 6/2/2016
mi
from
Boston, MA
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Neurology, Orthopedics / Podiatry, Other Clinical Trial
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Status: Enrolling
Updated: 6/2/2016
mi
from
Phoenix, AZ
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Chicago, IL
Click here to add this to my saved trials
Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
San Diego, CA
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Seattle, WA
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Imaging and BioFluid Biomarkers in Amyotrophic Lateral Sclerosis
Status: Enrolling, Phase
Updated: 3/21/2018
mi
from
Boston, MA
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Portland, OR
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ALS Clinical Trial
Non-invasive Brain Stimulation for the Treatment of Depression Symptoms in ALS
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boston, MA
Click here to add this to my saved trials
Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
San Francisco, CA
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Neurology, Other Clinical Trial
Open Label Extension Study of AMX0035 in Patients With ALS
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Boston, MA
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Seattle, WA
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Hershey, PA
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ALS Clinical Trial
Genomic Translation for Amyotrophic Lateral Sclerosis Care
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Los Angeles, CA
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Ann Arbor, MI
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Charleston, SC
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Neurology, Orthopedics / Podiatry, Other Clinical Trial
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Status: Enrolling
Updated: 6/2/2016
mi
from
Worcester, MA
Click here to add this to my saved trials
Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cleveland, OH
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Neurology, Other Clinical Trial
Deep Phenotyping in Patients With ALS
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Orange, CA
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Amyotrophic Lateral Sclerosis (ALS) Clinical Trial
Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Irvine, CA
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Neurology, Other Clinical Trial
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Vancouver,
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Cardiology / Vascular Diseases, Endocrinology, Neurology, Other Clinical Trial
Neurologic Stem Cell Treatment Study
Status: Enrolling
Updated: 12/31/1969
mi
from
Margate, FL
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Neurology, Other Clinical Trial
Open Label Extension Study of AMX0035 in Patients With ALS
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Worcester, MA
Click here to add this to my saved trials