Sarah Cannon Research Institute
3322 West End Avenue
Nashville, Tennessee 37203
(615)329-SCRI (7274) http://sarahcannonresearch.com

Use our guide to learn which trials are right for you!

Sarah Cannon Research Institute (SCRI) is a global strategic research organization focusing on advancing therapies for patients. It is one of the largest clinical research programs, conducting community-based clinical trials in oncology and cardiology through affiliations with a network of more than 700 physicians in the United States and United Kingdom. Additionally, SCRI offers management, regulatory and other research support services to drug development sponsors and strategic investigator sites.

SCRI sponsors oncology clinical trials through its affiliation with clinical oncology practices. This work makes it possible for thousands of cancer patients to participate in research studies in the communities where they live.

SCRI provides research support services to oncologists, hematologists and drug development sponsors.

We've found
74 trials
at this facility
Endocrinology, Hematology, Oncology Clinical Trial
A Safety and Tolerability Study of PCI-24781 in Subjects With Cancer
Status: Enrolling
Updated: 6/1/2012
mi
from
Nashville, TN
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Oncology Clinical Trial
Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
Status: Enrolling
Updated: 10/22/2013
mi
from
Nashville, TN
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Cancer Clinical Trial
Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced Cancer
Status: Enrolling
Updated: 5/30/2012
mi
from
Nashville, TN
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Oncology Clinical Trial
Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations.
Status: Enrolling, Phase I, II
Updated: 9/23/2015
mi
from
Nashville, TN
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Advanced Solid Tumors Clinical Trial
A Phase 1 Study of PT-112 Injection in Subjects With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 9/4/2015
mi
from
Nashville, TN
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Lymphoma Clinical Trial
A Phase 1 Study Evaluating CPI-0610 in Patients With Progressive Lymphoma
Status: Enrolling, Phase I
Updated: 1/13/2016
mi
from
Nashville, TN
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Advanced Cancer Clinical Trial
Phase 1/1b Study of MGCD516 in Patients With Advanced Cancer
Status: Enrolling, Phase I
Updated: 1/26/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II)
Status: Enrolling, Phase I, II
Updated: 3/14/2016
mi
from
Nashville, TN
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Clinical Trial
A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCHNC), Ovarian, Sarcoma, Hodgkin Lymphoma
Status: Enrolling, Phase I
Updated: 3/25/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas
Status: Enrolling, Phase III
Updated: 3/28/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of HER2+ Metastatic Breast Cancer
Status: Enrolling, Phase III
Updated: 4/1/2016
mi
from
Nashville, TN
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CANCER NOS Clinical Trial
Safety Study of BMS-986015 (Anti-KIR) in Combination With Ipilimumab in Subjects With Selected Advanced Tumor
Status: Enrolling, Phase I
Updated: 10/13/2014
mi
from
Nashville, TN
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Oncology Clinical Trial
Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma
Status: Enrolling, Phase I, II
Updated: 8/21/2015
mi
from
Nashville, TN
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Cancer Clinical Trial
PTC596 in Patients With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 7/24/2015
mi
from
Nashville, TN
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Oncology Clinical Trial
A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10
Status: Enrolling, Phase I
Updated: 8/28/2015
mi
from
Nashville, TN
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Oncology Clinical Trial
Phase I Dose Escalation Study of VS-4718 in Subjects With Metastatic Non-Hematologic Malignancies
Status: Enrolling, Phase I
Updated: 1/7/2016
mi
from
Nashville, TN
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B-Cell Lymphoma Clinical Trial
A Study Evaluating CPI-1205 in Patients With B-Cell Lymphomas
Status: Enrolling, Phase I
Updated: 1/13/2016
mi
from
Nashville, TN
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Malignant Melanoma Clinical Trial
Phase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Cutaneous Melanoma
Status: Enrolling, Phase I, II
Updated: 3/17/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
A Study Of PF-06647263 In Patients With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 3/22/2016
mi
from
Nashville, TN
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Advanced Cancer Clinical Trial
A Study to Evaluate the Safety and Pharmacokinetics of KTN0158 in Adult Patients With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 3/24/2016
mi
from
Nashville, TN
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ALK-positive Non Small Cell Lung Cancer (NSCLC) and ROS1-positive NSCLC Clinical Trial
A Study Of PF-06463922 An ALK/ROS1 Inhibitor In Patients With Advanced Non Small Cell Lung Cancer With Specific Molecular Alterations
Status: Enrolling, Phase I, II
Updated: 4/1/2016
mi
from
Nashville, TN
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Multiple Myeloma Clinical Trial
Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile
Status: Enrolling
Updated: 5/6/2015
mi
from
Nashville, TN
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Oncology Clinical Trial
The BEACON Study (Breast Cancer Outcomes With NKTR-102)
Status: Enrolling
Updated: 7/26/2013
mi
from
Nashville, TN
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Ovarian Cancer Clinical Trial
Phase I/Ib Study of Paclitaxel in Combination With VS-6063 in Patients With Advanced Ovarian Cancer
Status: Enrolling, Phase I
Updated: 9/9/2013
mi
from
Nashville, TN
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Oncology Clinical Trial
Dose-escalation, Safety and Pharmacokinetic Study of Briciclib in Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 5/1/2015
mi
from
Nashville, TN
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Oncology Clinical Trial
Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in NSCLC With Expansion Cohorts in NSCLC and Melanoma
Status: Enrolling, Phase I, II
Updated: 12/23/2015
mi
from
Nashville, TN
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Multiple Myeloma Clinical Trial
A Phase 1 Study Evaluating CPI-0610 in Patients With Previously Treated Multiple Myeloma
Status: Enrolling, Phase I
Updated: 1/13/2016
mi
from
Nashville, TN
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Breast Cancer Clinical Trial
A Safety Study of SGN-LIV1A in Breast Cancer Patients
Status: Enrolling, Phase I
Updated: 2/25/2016
mi
from
Nashville, TN
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Stage IV Small Cell Lung Cancer Clinical Trial
A Phase 1b/2 Study of OMP-59R5 in Combination With Etoposide and Platinum Therapy in Subjects With Untreated Extensive Stage Small Cell Lung Cancer (PINNACLE)
Status: Enrolling, Phase I, II
Updated: 2/26/2016
mi
from
Nashville, TN
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Locally Advanced or Metastatic Solid Tumors Clinical Trial
A Study of Demcizumab Plus Pembrolizumab +/- Chemotherapy
Status: Enrolling, Phase I
Updated: 3/24/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients
Status: Enrolling, Phase II, III
Updated: 3/31/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer
Status: Enrolling
Updated: 5/31/2012
mi
from
Nashville, TN
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Chronic Myeloid Leukemia Clinical Trial
Ponatinib in Newly Diagnosed Chronic Myeloid Leukemia (CML) (EPIC)
Status: Enrolling
Updated: 9/26/2013
mi
from
Nashville, TN
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Malignant Pleural Mesothelioma Clinical Trial
Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma
Status: Enrolling, Phase II
Updated: 9/23/2015
mi
from
Nashville, TN
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Multiple Myeloma Clinical Trial
Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma
Status: Enrolling, Phase II
Updated: 7/8/2014
mi
from
Nashville, TN
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Melanoma Clinical Trial
Phase 3 Trial in Subjects With Metastatic Melanoma Comparing 3 mg/kg Ipilimumab Versus 10 mg/kg Ipilimumab
Status: Enrolling
Updated: 3/28/2013
mi
from
Nashville, TN
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Small Cell Lung Cancer Clinical Trial
Study of G1T28 in Patients With Previously Treated Extensive Stage SCLC Receiving Topotecan Chemotherapy
Status: Enrolling, Phase I, II
Updated: 3/7/2016
mi
from
Nashville, TN
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Carcinoma, Non-Small-Cell Lung Clinical Trial
Phase II Safety and Tolerability Trial With Nab-Paclitaxel Plus Carboplatin Followed by Nab-Paclitaxel for First Line Treatment of NSCLC Subjects With ECOG PS 2
Status: Enrolling, Phase II
Updated: 3/30/2016
mi
from
Nashville, TN
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Advanced Cancer Clinical Trial
A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced Tumors
Status: Enrolling, Phase I
Updated: 3/30/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia
Status: Enrolling, Phase I
Updated: 3/27/2014
mi
from
Nashville, TN
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Hematology, Oncology Clinical Trial
An Extension Study for Patients Who Are Deriving Benefit With Idelalisib (GS-1101; CAL-101) Following Completion of a Prior Idelalisib Study
Status: Enrolling
Updated: 6/28/2013
mi
from
Nashville, TN
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FOLR-1 Positive Solid Tumors Clinical Trial
First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IMGN853 in Adults With Ovarian Cancer and Other FOLR1-Positive Solid Tumors
Status: Enrolling, Phase I
Updated: 10/5/2015
mi
from
Nashville, TN
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Hematology, Oncology Clinical Trial
Study of Sotatercept for the Treatment of Anemia in low-or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Chronic Myelomonocytic Leukemia (CMML)
Status: Enrolling, Phase II
Updated: 5/6/2015
mi
from
Nashville, TN
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Hematology, Oncology Clinical Trial
Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-907 in Patients With Lymphoma or Multiple Myeloma
Status: Enrolling, Phase I
Updated: 7/27/2015
mi
from
Nashville, TN
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Oncology Clinical Trial
Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies
Status: Enrolling, Phase I
Updated: 1/7/2016
mi
from
Nashville, TN
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Metastatic Small Cell Lung Cancer Clinical Trial
Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects With Metastatic Small Cell Lung Cancer
Status: Enrolling, Phase II
Updated: 1/20/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 2/1/2016
mi
from
Nashville, TN
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Solid Tumors Clinical Trial
A Phase 1 Trial of a Novel XPO1 Inhibitor in Patients With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 2/19/2016
mi
from
Nashville, TN
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Acute Myeloid Leukemia Clinical Trial
A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: Enrolling, Phase I, II
Updated: 3/25/2016
mi
from
Nashville, TN
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Her2 Positive Breast Cancer Clinical Trial
Study of ONT-380 vs Placebo in Combo w/ Capecitabine & Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer
Status: Enrolling, Phase II
Updated: 3/30/2016
mi
from
Nashville, TN
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Advanced Malignancies Clinical Trial
Companion Study for Patients Who Completed Participation in a REGN2810 (Anti-PD-1) Clinical Study
Status: Upcoming, Phase I
Updated: 8/10/2015
mi
from
Nashville, TN
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Hematology, Oncology Clinical Trial
SGI-110 in Patients With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)
Status: Enrolling, Phase I, II
Updated: 1/8/2016
mi
from
Nashville, TN
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Malignant Melanoma Clinical Trial
Study to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant Melanoma
Status: Enrolling, Phase I
Updated: 2/10/2016
mi
from
Nashville, TN
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Hematological Malignancies Clinical Trial
Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced Hematological Cancer
Status: Enrolling, Phase I
Updated: 2/22/2016
mi
from
Nashville, TN
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Non Squamous Lung Cancer Clinical Trial
A Clinical Trial Testing The Efficacy Of Crizotinib Versus Standard Chemotherapy Pemetrexed Plus Cisplatin Or Carboplatin In Patients With ALK Positive Non Squamous Cancer Of The Lung
Status: Enrolling, Phase III
Updated: 2/25/2016
mi
from
Nashville, TN
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HER2 Positive Breast Cancers Clinical Trial
A Phase 1b Study of ONT-380 Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer
Status: Enrolling, Phase I
Updated: 3/2/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
A Study of Idelalisib and Rituximab in Elderly Patients With Untreated CLL or SLL
Status: Enrolling, Phase II
Updated: 2/22/2016
mi
from
Nashville, TN
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Stage IV Pancreatic Cancer Clinical Trial
A Phase 1b/2 Study of OMP-59R5 in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer
Status: Enrolling, Phase I, II
Updated: 3/7/2016
mi
from
Nashville, TN
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Chronic Lymphocytic Leukemia Clinical Trial
Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia
Status: Enrolling, Phase III
Updated: 3/21/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Status: Enrolling, Phase III
Updated: 1/5/2016
mi
from
Nashville, TN
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HER2 Positive Metastatic Breast Cancers Clinical Trial
A Phase 1b Study of ONT-380 Combined With Capecitabine and/or Trastuzumab in Patients With HER2+ Metastatic Breast Cancer
Status: Enrolling, Phase I
Updated: 1/25/2016
mi
from
Nashville, TN
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High Risk Acute Myeloid Leukemia Clinical Trial
Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia
Status: Enrolling, Phase III
Updated: 2/23/2016
mi
from
Nashville, TN
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Clinical Trial
LONGEVITY Study. Evaluation of the Device and Battery Longevity of Boston Scientific Market-released ICD and CRT-D Devices
Status: Enrolling
Updated: 3/2/2016
mi
from
Nashville, TN
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Advanced Solid Tumors Clinical Trial
Safety Study of X-82 in Patients With Advanced Solid Tumors
Status: Enrolling, Phase I
Updated: 3/8/2016
mi
from
Nashville, TN
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Advanced Multiple Myeloma Clinical Trial
A Study of Filanesib (ARRY-520) and Carfilzomib in Patients With Advanced Multiple Myeloma
Status: Enrolling, Phase II
Updated: 3/22/2016
mi
from
Nashville, TN
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Unresectable or Metastatic Melanoma Clinical Trial
Phase 3 Study of Nivolumab or Nivolumab Plus Ipilimumab Versus Ipilimumab Alone in Previously Untreated Advanced Melanoma (CheckMate 067)
Status: Enrolling, Phase III
Updated: 3/28/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
Study of ONT-10 and Varlilumab to Treat Advanced Ovarian or Breast Cancer
Status: Enrolling, Phase I
Updated: 3/29/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
IMGN529 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia
Status: Enrolling, Phase I
Updated: 1/28/2016
mi
from
Nashville, TN
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Hematology, Oncology Clinical Trial
Safety, Pharmacokinetics, and Pharmacodynamics of Oral Azacitidine in Subjects With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia and Acute Myelogenous Leukemia
Status: Enrolling, Phase I
Updated: 3/24/2016
mi
from
Nashville, TN
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Breast Neoplasms Clinical Trial
A Study of Palbociclib (PD-0332991) + Letrozole vs. Letrozole For 1st Line Treatment Of Postmenopausal Women With ER+/HER2- Advanced Breast Cancer (PALOMA-2)
Status: Enrolling, Phase III
Updated: 3/29/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
Study of the Combination of KD019 and Trastuzumab in Subjects With HER2-Positive Metastatic Breast Cancer
Status: Enrolling, Phase I, II
Updated: 3/9/2016
mi
from
Nashville, TN
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Oncology Clinical Trial
A Phase 1 Pilot Study of the Subcutaneous (s.c.) Route to Facilitate the Administration of RRx-001
Status: Enrolling, Phase I
Updated: 1/19/2016
mi
from
Nashville, TN
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Non-Hodgkin's Lymphoma Clinical Trial
Safety and Efficacy Study of an Anti-CD20 Monoclonal Antibody (AME-133v) to Treat Non-Hodgkin's Lymphoma
Status: Enrolling, Phase I
Updated: 1/5/2016
mi
from
Nashville, TN
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Carcinoma, Non-Small-Cell Lung Clinical Trial
An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene
Status: Enrolling, Phase III
Updated: 2/4/2016
mi
from
Nashville, TN
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