A Study Comparing LY900014 to Insulin Lispro (Humalog) in Children and Adolescents With Type 1 Diabetes
| Status: | Not yet recruiting | 
|---|---|
| Conditions: | Diabetes, Diabetes | 
| Therapuetic Areas: | Endocrinology | 
| Healthy: | No | 
| Age Range: | 1 - 17 | 
| Updated: | 4/5/2019 | 
| Start Date: | April 22, 2019 | 
| End Date: | January 2, 2021 | 
| Contact: | There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or | 
| Email: | clinicaltrials.gov@lilly.com | 
| Phone: | 1-317-615-4559 | 
A Prospective, Randomized, Double-Blind Comparison of LY900014 to Humalog With an Open-Label Postprandial LY900014 Treatment Group in Children and Adolescents With Type 1 Diabetes
The reason for this study is to compare the study drug LY900014 to insulin lispro (Humalog)
in children and adolescents with type 1 diabetes (T1D).
			in children and adolescents with type 1 diabetes (T1D).
Inclusion Criteria:
- T1D for at least 6 months at the screening visit.
- Have been treated with only one of the following rapid-acting insulin analogs as part
of an multiple daily injection regimen for at least the last 90 days prior to the
screening visit:
- insulin lispro U-100, or
- insulin aspart
- insulin glulisine or
- fast acting insulin aspart
- Have been treated with only one of the following basal insulins for at least the last
90 days prior to the screening visit:
- insulin glargine U-100 (once a day [QD] or twice a day [BID]), or
- insulin detemir U-100 (QD or BID), or
- insulin degludec U-100 (QD)
- Have a HbA1c value ≥6.5% and ≤9.5% at the screening visit.
Exclusion Criteria:
- Have current hypoglycemic unawareness or have had more than 1 episode of severe
hypoglycemia within 6 months prior to the screening visit.
- Have had more than 1 emergency room visit or hospitalization due to poor glucose
control within 6 months prior to the screening visit.
- Have been on a treatment regimen that includes regular human insulin, neutral
protamine Hagedorn (NPH), Afrezza® (insulin human) inhalation powder, any premixed
insulins or use of diluted insulins within 90 days prior to the screening visit.
We found this trial at
    26
    sites
	
									1720 2nd Ave S
Birmingham, Alabama 35233
	
			Birmingham, Alabama 35233
(205) 934-4011  
							 
					Principal Investigator: Mary Lauren Scott
			
						
										Phone: 2059969569
					
		University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...  
  
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									3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
	
			Cincinnati, Ohio 45229
 1-513-636-4200  
							 
					Principal Investigator: Nicole Sheanon
			
						
										Phone: 513-636-4744
					
		Cincinnati Children's Hospital Medical Center Patients and families from across the region and around the...  
  
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									2401 Gillham Rd
Kansas City, Missouri 64108
	
			Kansas City, Missouri 64108
(816) 234-3000 
							 
					Principal Investigator: Mark A Clements
			
						
										Phone: 816-855-1769
					
		Children's Mercy Hospital Children's Mercy Hospitals and Clinics continues redefining pediatric medicine throughout the Midwest...  
  
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									South 34th Street
Philadelphia, Pennsylvania 19104
	
			Philadelphia, Pennsylvania 19104
 215-590-1000 
							 
					Principal Investigator: Steven Willi
			
						
										Phone: 215-426-7037
					
		Children's Hospital of Philadelphia Since its start in 1855 as the nation's first hospital devoted...  
  
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									3020 Childrens way
San Diego, California 92123
	
			San Diego, California 92123
(858) 576-1700
							 
					Principal Investigator: Michael E Gottschalk
			
						
								
		Rady Children's Hospital - San Diego Rady Children's Hospital-San Diego is the region’s pediatric medical...  
  
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									4202 E Fowler Ave
Tampa, Florida 33620
	
			Tampa, Florida 33620
(813) 974-2011
							 
					Principal Investigator: Henry Rodriguez
			
						
										Phone: 813-396-2580
					
		University of South Florida The University of South Florida is a high-impact, global research university...  
  
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								Atlanta, Georgia 30318			
	
			
					Principal Investigator: Quentin VanMeter
			
						
										Phone: 678-961-2100
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								Baltimore, Maryland 21229			
	
			
					Principal Investigator: Barry Reiner
			
						
										Phone: 410-646-4009
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									6400 Perkins Rd
Baton Rouge, Louisiana 70808
	
			Baton Rouge, Louisiana 70808
(225) 763-2500
							 
					Principal Investigator: Daniel Hsia
			
						
										Phone: 225-763-2831
					
		Pennington Biomedical Research Center Unlike other medical research facilities where science occurs in separate labs...  
  
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								Boise, Idaho 83712			
	
			
					Principal Investigator: Daniel Flynn
			
						
										Phone: 208-381-7340
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									One Joslin Place
Boston, Massachusetts 02215
	
			Boston, Massachusetts 02215
617-309-2400
							 
					Principal Investigator: Lori M Laffel
			
						
										Phone: 617-732-2603
					
		Joslin Diabetes Center Joslin Diabetes Center, located in Boston, Massachusetts, is the world's largest diabetes...  
  
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								Graz, Steiermark 			
	
			
					Principal Investigator: Elke Fröhlich-Reiterer
			
						
										Phone: 4331638580562
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								Idaho Falls, Idaho 83404			
	
			
					Principal Investigator: Joshua Smith
			
						
										Phone: 208-523-1122
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								Indianapolis, Indiana 46202			
	
			
					Principal Investigator: Linda DiMeglio
			
						
										Phone: 317-944-3889
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								Los Angeles, California 90027			
	
			
					Principal Investigator: Roshanak Monzavi
			
						
										Phone: 323-631-7040
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								Lufkin, Texas 75904			
	
			
					Principal Investigator: Lance Sloan
			
						
										Phone: 936-632-4282
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									333 Cedar St
New Haven, Connecticut 06504
	
			New Haven, Connecticut 06504
(203) 432-4771
							 
					Principal Investigator: Jennifer L Sherr
			
						
										Phone: 203-737-5831
					
		Yale University School of Medicine Founded in 1810, the Yale School of Medicine is a...  
  
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								Orlando, Florida 32803			
	
			
					Principal Investigator: Konda Reddy
			
						
										Phone: 407-896-2901
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								Palo Alto, California 94304			
	
			
					Principal Investigator: BRUCE BUCKINGHAM
			
						
										Phone: 650-725-6549
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								Sacramento, California 98521			
	
			
					Principal Investigator: Gnanagurudasan Prakasam
			
						
										Phone: 916-426-1902
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								Syracuse, New York 13210			
	
			
					Principal Investigator: Ruth S Weinstock
			
						
										Phone: 315-464-9006
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								Tacoma, Washington 98405			
	
			
					Principal Investigator: Gadi B. Kletter
			
						
										Phone: 253-403-7250
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								Tucson, Arizona 85721			
	
			(520) 621-2211
							 
					Principal Investigator: Mark Wheeler
			
						
										Phone: 520-626-6077
					
		University of Arizona The University of Arizona is a premier, public research university. Established in...  
  
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									1031 Office Park Road
West Des Moines, Iowa 50265
	
			
					West Des Moines, Iowa 50265
Principal Investigator: Anuj Bhargava
			
						
										Phone: 515-329-6800
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