A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder



Status:Recruiting
Conditions:Cancer, Cancer, Bladder Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:4/5/2019
Start Date:May 25, 2018
End Date:April 16, 2023
Contact:Recruiting sites have contact information. Please contact the sites directly. If there is no contact information,
Email:ClinicalTrials@bms.com
Phone:please email

Use our guide to learn which trials are right for you!

A Phase 2, Randomized, Open-label Study of Nivolumab or Nivolumab/BMS-986205 Alone or Combined With Intravesical BCG in Participants With BCG-Unresponsive, High-Risk, Non-Muscle Invasive Bladder Cancer

A study to evaluate Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 with or
without BCG in BCG-Unresponsive non-muscle invasive Bladder Cancer


For more information regarding Bristol-Myers Squibb Clinical Trial participation, please
visit www.BMSStudyConnect.com

Inclusion Criteria:

- Pathologically demonstrated BCG-unresponsive, high-risk non-muscle-invasive bladder
cancer (NMIBC) defined as CIS with or without papillary component, any T1, or Ta
high-grade lesions

- Predominant histologic component (> 50%) must be urothelial (transitional cell)
carcinoma

- Eastern Cooperative Oncology Group (ECOG) performance status 0-1

Exclusion Criteria:

- Sign of locally advanced disease or metastatic bladder cancer

- Urothelial cancer (UC) in the upper genitourinary tract (kidneys, renal collecting
systems, ureters) within 24 months of enrollment

- Prior immuno-oncology therapy

Other protocol defined inclusion/exclusion criteria could apply
We found this trial at
30
sites
201 Dowman Dr
Atlanta, Georgia 30303
(404) 727-6123
Phone: 404-778-3840
Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
5801 South Ellis Avenue
Chicago, Illinois 60637
 773.702.1234
Phone: 773-834-1580
University of Chicago One of the world's premier academic and research institutions, the University of...
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Ann Arbor, Michigan 48109
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Bala-Cynwyd, Pennsylvania 19004
?
mi
from
Bala-Cynwyd, PA
Click here to add this to my saved trials
Baltimore, Maryland 21237
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Capital Federal, Buenos Aires
Phone: +541132218900
?
mi
from
Capital Federal,
Click here to add this to my saved trials
171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Phone: 843-792-9321
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Chattanooga, Tennessee 37403
Phone: 423-778-2982
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
Columbus, Ohio 43210
Phone: 614-366-9086
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Dallas, Texas 75231
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Hershey, Pennsylvania 17033
?
mi
from
Hershey, PA
Click here to add this to my saved trials
Houston, Texas 77030
Phone: 713-563-7458
?
mi
from
Houston, TX
Click here to add this to my saved trials
1441 Eastlake Ave
Los Angeles, California 90033
(323) 865-3000
U.S.C./Norris Comprehensive Cancer Center The USC Norris Comprehensive Cancer Center, located in Los Angeles, is...
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Lubbock, Texas
?
mi
from
Lubbock, TX
Click here to add this to my saved trials
Minneapolis, Minnesota 55416
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
823 82nd Parkway, Suite B
Myrtle Beach, South Carolina 29572
(843) 449-1010 ext.268
Carolina Urologic Research Center Carolina Urologic Research Center (CURC) has been recognized both nationally and...
?
mi
from
Myrtle Beach, SC
Click here to add this to my saved trials
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
New York, New York 10016
?
mi
from
New York, NY
Click here to add this to my saved trials
Omaha, Nebraska 68114
Phone: 402-399-7892
?
mi
from
Omaha, NE
Click here to add this to my saved trials
Phoenix, Arizona 85016
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Riverside, California 92501
?
mi
from
Riverside, CA
Click here to add this to my saved trials
San Antonio, Texas 78229
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
San Francisco, California 94107
?
mi
from
San Francisco, CA
Click here to add this to my saved trials
Shreveport, Louisiana 71103
?
mi
from
Shreveport, LA
Click here to add this to my saved trials
Springfield, Oregon 97477
?
mi
from
Springfield, OR
Click here to add this to my saved trials
Tampa, Florida 33612
?
mi
from
Tampa, FL
Click here to add this to my saved trials
4500 Main Street
Virginia Beach, Virginia 23462
?
mi
from
Virginia Beach, VA
Click here to add this to my saved trials
Voorhees, New Jersey 08043
Phone: 856-673-1613
?
mi
from
Voorhees, NJ
Click here to add this to my saved trials
Westwood, Kansas 66205
?
mi
from
Westwood, KS
Click here to add this to my saved trials
Wichita, Kansas 67226
?
mi
from
Wichita, KS
Click here to add this to my saved trials