Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis



Status:Enrolling by invitation
Conditions:Gastrointestinal, Gastrointestinal, Gastrointestinal, Hepatitis
Therapuetic Areas:Gastroenterology, Immunology / Infectious Diseases
Healthy:No
Age Range:18 - 75
Updated:5/4/2018
Start Date:February 14, 2017
End Date:October 31, 2019

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Open-label Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects With Nonalcoholic Steatohepatitis (NASH)

This rollover study will provide open-label treatment with cenicriviroc and will assess the
long-term safety of continued treatment with cenicriviroc in participants who participated in
the CENTAUR study 652-2-203 [NCT02217475].


Inclusion Criteria:

-Successful completion of both Treatment Period 1 and Treatment Period 2, of the CENTAUR
Study (652-2-203), including a Year 2 liver biopsy.

Exclusion Criteria:

- Prior or planned liver transplantation

- Other know causes of chronic liver disease such as: Alcoholic liver disease, Primary
biliary cirrhosis, Primary sclerosing cholangitis, Autoimmune hepatitis, Wilson's
disease, hemochromatosis, or iron overload, or Alpha-1-antitrypsis (A1AT) deficiency.
We found this trial at
35
sites
Durham, North Carolina 27710
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185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
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Boston, MA
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201 Presidents Circle
Salt Lake City, Utah 84108
801) 581-7200
University of Utah Research is a major component in the life of the U benefiting...
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500 S State St
Ann Arbor, Michigan 48109
(734) 764-1817
University of Michigan The University of Michigan was founded in 1817 as one of the...
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Ann Arbor, MI
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345 Saint Paul Place
Baltimore, Maryland 21202
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733 North Broadway
Baltimore, Maryland 21205
(410) 955-3182
Johns Hopkins University School of Medicine Johns Hopkins Medicine (JHM), headquartered in Baltimore, Maryland, is...
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Buffalo, NY
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Chattanooga, Tennessee 37421
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1653 W. Congress Parkway
Chicago, Illinois 60612
(312) 942-5000
Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
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Chicago, IL
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Cincinnati, OH
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480 Honeysuckle Road
Dothan, Alabama 36305
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Dothan, AL
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2510 Lakeland Drive
Flowood, Mississippi 39232
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Germantown, Tennessee 38138
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Houston, TX
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La Jolla, California 92093
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7760 West 38th Avenue
Littleton, Colorado 80120
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Live Oak, Texas 78233
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Louisville, Kentucky 40202
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New Orleans, Louisiana 70112
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Phoenix, Arizona
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3100 Duraleigh Road
Raleigh, North Carolina 27612
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Rialto, California 92377
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Richmond, VA
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Saint Paul, Minnesota 55114
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San Antonio, Texas 78215
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San Antonio, Texas 78234
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34800 Bob Wilson Drive
San Diego, California 92103
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San Francisco, California 94115
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5300 Tallman Ave NW
Seattle, Washington 98122
(206) 782-2700
Swedish Medical Center Since 1910, Swedish has been the region's hallmark for excellence in health...
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Seattle, Washington 98101
(888) 862-2737
Virginia Mason Medical Center Established in 1920, Virginia Mason began as an 80-bed hospital with...
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Tampa, FL
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Tucson, Arizona 85712
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Tupelo, Mississippi 38801
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1901 S Hawthorne Rd #306
Winston-Salem, North Carolina 27103
(336) 768-8062
PMG Research of Winston-Salem PMG Research of Winston-Salem, founded in 1979, occupies a 10,000 square...
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