Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Patients With Untreated Inoperable or Metastatic Urothelial Cancer



Status:Recruiting
Conditions:Prostate Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:1/17/2019
Start Date:March 24, 2017
End Date:December 23, 2022
Contact:Recruiting sites have contact information. Please contact the sites directly. If there is no contact information,
Email:Clinical.Trials@bms.com
Phone:please email:

Use our guide to learn which trials are right for you!

A Phase 3, Open-label, Randomized Study of Nivolumab Combined With Ipilimumab, or With Standard of Care Chemotherapy, Versus Standard of Care Chemotherapy in Participants With Previously Untreated Unresectable or Metastatic Urothelial Cancer

The purpose of this study is to determine whether an investigational immunotherapy nivolumab
in combination with ipilimumab or in combination with standard of care chemotherapy is more
effective than standard of care chemotherapy alone in treating patients with previously
untreated inoperable or metastatic urothelial cancer.


For more information regarding Bristol-Myers Squibb Clinical Trial participation, please
visit www.BMSStudyConnect.com

Inclusion Criteria:

- Metastatic or inoperable urothelial cancer

- Must have at least 1 lesion with measurable disease

- Must have full activity or, if limited, must be able to walk and carry out activities
such as light house work or office work

- No prior systemic chemotherapy treatment in the metastatic setting

Exclusion Criteria:

- Patients with disease that is suitable for local therapy administered with

curative intent

- Patients with active brain metastases or leptomeningeal metastases

- Patients with active, known or suspected autoimmune disease

- Prior treatment with an anti-PD1, anti-PDL1, anti-PDL2, anti-CD137, or anti-CTLA4
antibody, or any other antibody or drug specifically targeting T-cell co-stimulation
or checkpoint pathways

Other protocol defined inclusion/exclusion criteria could apply
We found this trial at
38
sites
Boca Raton, Florida 33486
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
?
mi
from
Boston, MA
Click here to add this to my saved trials
666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
?
mi
from
Buffalo, NY
Click here to add this to my saved trials
4725 North Federal Highway
Fort Lauderdale, Florida 33308
(954) 771-8000
Phone: 954-267-7750
Holy Cross Hospital While spirituality plays an essential role in the way that we minister...
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
4805 Northeast Glisan Street
Portland, Oregon 97213
(503) 215-1111
Phone: 503-215-2604
Providence Portland Medical Center We strive to give those we serve exceptional, compassionate health care...
?
mi
from
Portland, OR
Click here to add this to my saved trials
Albuquerque, New Mexico 87131
(505) 277-0111
Phone: 505-272-7813
University of New Mexico Founded in 1889 as New Mexico’s flagship institution, the University of...
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
Anchorage, Alaska 99503
Phone: 907-276-1455
?
mi
from
Anchorage, AK
Click here to add this to my saved trials
Athens, Georgia 30607
Phone: 706-353-2990
?
mi
from
Athens, GA
Click here to add this to my saved trials
Birmingham, Alabama 35294
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Boston, Massachusetts 02215
?
mi
from
Boston, MA
Click here to add this to my saved trials
Boston, Massachusetts 02215
?
mi
from
Boston, MA
Click here to add this to my saved trials
450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Phone: 617-582-7334
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
?
mi
from
Boston, MA
Click here to add this to my saved trials
Burnsville, Minnesota 55337
Phone: 952-836-3608
?
mi
from
Burnsville, MN
Click here to add this to my saved trials
Capital Federal, Buenos Aires
Phone: +541132218900
?
mi
from
Capital Federal,
Click here to add this to my saved trials
2035 W Taylor St
Chicago, Illinois
(312) 996-4350
Phone: 312-996-1588
University of Illinois at Chicago A major research university in the heart of one of...
?
mi
from
Chicago, IL
Click here to add this to my saved trials
281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Phone: 919-681-9822
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
?
mi
from
Durham, NC
Click here to add this to my saved trials
2615 East Clinton Avenue
Fresno, California 93703
Phone: 559-225-6100
?
mi
from
Fresno, CA
Click here to add this to my saved trials
Hattiesburg, Mississippi 39401
Phone: 601-288-2495
?
mi
from
Hattiesburg, MS
Click here to add this to my saved trials
200 Technology Drive
Hooksett, New Hampshire 03106
Phone: 603-622-6484
?
mi
from
Hooksett, NH
Click here to add this to my saved trials
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Iowa City, Iowa 52242
?
mi
from
Iowa City, IA
Click here to add this to my saved trials
Jacksonville, Florida 32256
Phone: 904-363-7462
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Kansas City, Missouri 64111
Phone: 816-932-2677
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Kirkland, Washington 98034
Phone: 425-899-3977
?
mi
from
Kirkland, WA
Click here to add this to my saved trials
Little Rock, Arkansas 72201
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
Milwaukee, Wisconsin 53226
?
mi
from
Milwaukee, WI
Click here to add this to my saved trials
259 1st St
Mineola, New York 11501
(516) 663-0333
Phone: 516-663-3115
Winthrop University Hospital Founded in 1896 by a group of local physicians and concerned citizens,...
?
mi
from
Mineola, NY
Click here to add this to my saved trials
New Orleans, Louisiana 70121
Phone: 504-703-2652
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
New York, New York 10016
?
mi
from
New York, NY
Click here to add this to my saved trials
1428 Madison Ave
New York, New York 10029
(212) 241-6500
Phone: 212-824-7117
Icahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai is...
?
mi
from
New York, NY
Click here to add this to my saved trials
Omaha, Nebraska 68130
Phone: 402-991-8468
?
mi
from
Omaha, NE
Click here to add this to my saved trials
320 E North Ave
Pittsburgh, Pennsylvania 15212
(412) 359-3131
Phone: 412-359-6452
Allegheny General Hospital At Allegheny General Hospital, our physicians and healthcare staff have earned an...
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Phone: 314-747-1343
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Salt Lake City, Utah 84132
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
Santa Rosa, California 95403
Phone: 707-521-3830
?
mi
from
Santa Rosa, CA
Click here to add this to my saved trials
Thomasville, Georgia 31792
Phone: 229-584-5417
?
mi
from
Thomasville, GA
Click here to add this to my saved trials
Ypsilanti, Michigan 48197
Phone: 734-712-5674
?
mi
from
Ypsilanti, MI
Click here to add this to my saved trials