An Investigational Immuno-therapy Study of Nivolumab or Placebo in Patients With Resected Esophageal or Gastroesophageal Junction Cancer



Status:Recruiting
Conditions:Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:1/31/2019
Start Date:May 23, 2016
End Date:October 11, 2024
Contact:Recruiting sites have contact information. Please contact the sites directly. If there is no contact information, please email:
Email:Clinical.Trials@bms.com

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A Randomized, Multicenter, Double Blind, Phase III Study of Adjuvant Nivolumab or Placebo in Subjects With Resected Esophageal, or Gastroesophageal Junction Cancer

The purpose of this study is to determine whether Nivolumab will improve overall survival,
disease-free survival, or both compared with placebo.


Inclusion Criteria:

- Diagnosed with Stage II/III carcinoma of the esophagus or gastroesophageal junction

- Completed pre-operative chemo radiotherapy followed by surgery

- Diagnosed with residual pathologic disease after being surgically rendered free of
disease with negative margins following complete resection

Exclusion Criteria:

- Diagnosed with cervical esophageal carcinoma

- Diagnosed with Stage IV resectable disease

- Did not receive concurrent chemoradiotherapy prior to surgery
We found this trial at
43
sites
Saint Petersburg, Florida 33705
Phone: 919-681-7648
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330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Phone: 617-632-9265
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
Phone: 617-632-5588
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5801 South Ellis Avenue
Chicago, Illinois 60637
 773.702.1234
Phone: 773-834-0475
University of Chicago One of the world's premier academic and research institutions, the University of...
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Chicago, IL
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3840 Broadway
Fort Myers, Florida 33901
(239) 275-6400
Phone: 941-408-0500
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1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Phone: 615-343-7602
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Phone: 503-494-7702
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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Seattle, Washington 98104
(206) 543-2100
Phone: 206-667-7844
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1200 S Cedar Crest Blvd
Allentown, Pennsylvania 18103
(610) 402-8000
Phone: 610-402-1642
Lehigh Valley Hospital At Lehigh Valley Health Network, we continually go the extra mile to...
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Aurora, Colorado 80045
Phone: 720-848-0643
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Aurora, Colorado 80045
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Baltimore, Maryland 21231
Phone: 410-502-3696
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55 Fruit Street
Boston, Massachusetts 02215
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Phone: 617-632-5588
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Bronx, New York 10461
Phone: 718-405-8404
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2061 Avenida Caseros
Capital Federal, Buenos Aires C1264
Phone: +541143040006
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Charlotte, North Carolina 28211
Phone: 980-993-5484
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11100 Euclid Ave
Cleveland, Ohio 44106
(216) 844-1000
Phone: 216-844-9840
University Hospitals of Cleveland The history of University Hospitals Case Medical Center is linked to...
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4500 S. Lancaster Rd.
Dallas, Texas 75216
800-849-3597
Phone: 214-857-0737
Dallas VA Medical Center VA North Texas Health Care System (VANTHCS) is a progressive health...
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Dallas, Texas 75246
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Durham, North Carolina 27710
Phone: 919-668-1861
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Fargo, North Dakota 58122
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30 Prospect Ave
Hackensack, New Jersey 07601
(201) 996-2000
Phone: 551-996-4725
Hackensack University Medical Center Hackensack University Medical Center, part of the Hackensack University Health Network,...
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1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
Phone: 713-792-2828
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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Jacksonville, Florida 32256
Phone: 904-538-4488
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Los Angeles, California 90033
Phone: 213-764-3955
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Madison, Wisconsin 53792
(608) 263-2400
Phone: 800-622-8922
University of Wisconsin In achievement and prestige, the University of Wisconsin–Madison has long been recognized...
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1475 NW 12th Ave
Miami, Florida 33136
(305) 243-1000
Phone: 305-243-0116
University of Miami, Sylvester Comprehensive Cancer Center Sylvester Comprehensive Cancer Center integrates all cancer-related activities...
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3322 West End Avenue
Nashville, Tennessee 37203
(615)329-SCRI (7274)
Phone: 615-320-5090
Sarah Cannon Research Institute Sarah Cannon Research Institute (SCRI) is a global strategic research organization...
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Neptune, New Jersey 07754
Phone: 732-776-2421
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New York, New York 10016
Phone: 212-731-5770
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Oklahoma City, Oklahoma 73103
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Pensacola, Florida 32504
Phone: 850-416-2730
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Philadelphia, Pennsylvania 19111
Phone: 215-214-1676
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Phoenix, Arizona 85016
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PIttsburgh, Pennsylvania 15212
Phone: 412-578-5393
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660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Phone: 314-362-6963
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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San Francisco, California 94115
Phone: 415-600-3472
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San Francisco, California 94115
Phone: 415-353-7286
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Seattle, Washington 98109
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Sioux Falls, South Dakota 57104
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Temple, Texas 76508
Phone: 254-724-5939
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3800 Reservoir Rd NW
Washington, District of Columbia 20007
(202) 687-7695
Phone: 202-444-1781
Georgetown University Medical Center Georgetown University Medical Center is committed to excellence in research, education...
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