A Phase I Open Label Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma
| Status: | Completed |
|---|---|
| Conditions: | Blood Cancer, Hematology, Hematology |
| Therapuetic Areas: | Hematology, Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 11/3/2017 |
| Start Date: | December 9, 2014 |
| End Date: | October 10, 2017 |
A Phase I Open Label Dose Escalation and Randomized Cohort Expansion Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma
To assess the safety and tolerability, characterize the dose limiting toxicities (DLTs) and
identify the maximally tolerated dose (MTD) of Elotuzumab administered in combination with
either Lirilumab or Urelumab in subjects with multiple myeloma.
identify the maximally tolerated dose (MTD) of Elotuzumab administered in combination with
either Lirilumab or Urelumab in subjects with multiple myeloma.
Allocation:
- Part1: Non-randomized
- Part2: Randomized
- Part1: Non-randomized
- Part2: Randomized
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com
Inclusion Criteria:
- Subjects must have histological confirmation of multiple myeloma with measurable
disease (per International Myeloma Working Group (IMWG) criteria):
- Relapsed/refractory multiple myeloma, subjects who are post autologous transplant
and have achieved very good partial response (VGPR) or complete response (nCR)
with minimal residual disease (MRD)
We found this trial at
7
sites
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529 West Markham Street
Little Rock, Arkansas 72205
Little Rock, Arkansas 72205
(501) 686-7000
University of Arkansas for Medical Sciences The University of Arkansas for Medical Sciences (UAMS) in...
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Phone: 503-494-1453
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
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1275 York Ave
New York, New York 10021
New York, New York 10021
(212) 639-2000
Phone: 212-639-3069
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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3451 Walnut St
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Phone: 215-615-5853
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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