Adherence in Pediatric Multiple Sclerosis



Status:Recruiting
Conditions:Neurology, Neurology, Multiple Sclerosis
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:10 - 18
Updated:4/2/2016
Start Date:January 2013
Contact:Stephanie A Grover, MSc, CCRP
Email:stephanie.grover@sickkids.ca
Phone:416-813-7654

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Treatment Adherence in Pediatric Multiple Sclerosis

Disease modifying therapies (DMT) are widely used for children and adolescents with MS.
Nonetheless, many pediatric patients continue to relapse and therefore require changes in
therapy. We designed this research study to learn more about medication use in children and
adolescents with MS. We are also interested in learning what a behavioral feedback
intervention can tell us about adherence to medicine. Finally, we hope this research project
will inform the way we provide clinical care for children and adolescents with MS.


Inclusion Criteria:

- Adolescent boys/girls who are 10 to 17 years 11 months old;

- Have a diagnosis of MS, as per revised McDonald diagnostic criteria and International
Pediatric MS Study Group criteria;

- Prescribed with an oral or injectable disease-modifying therapy for MS for at least
six months.

Exclusion Criteria:

- Have non-specific white matter abnormalities and metabolic or infectious etiologies
for white matter abnormalities. This is indicative of not having a true diagnosis of
MS.

- Patients on IV DMT will not be included in the study.

- Non-English speaking patients
We found this trial at
11
sites
Loma Linda University
Loma Linda, California 92354
(909) 558-4000
Loma Linda University Loma Linda University (LLU) is a Seventh-day Adventist educational health-sciences institution with...
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Loma Linda, CA
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9500 Euclid Avenue
Cleveland, Ohio 44106
216.444.2200
Cleveland Clinic Cleveland Clinic is committed to principles as presented in the United Nations Global...
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Cleveland, OH
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1200 Moursund Street
Houston, Texas 77030
(713) 798-4951
Baylor College of Medicine Baylor College of Medicine in Houston, the only private medical school...
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Houston, TX
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South 34th Street
Philadelphia, Pennsylvania 19104
 215-590-1000
Children's Hospital of Philadelphia Since its start in 1855 as the nation's first hospital devoted...
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Philadelphia, PA
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4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
(412) 624-4141
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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Pittsburgh, PA
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1 Brookings Drive
St. Louis, Missouri 63110
 (314) 935-5000
Washington University Washington University creates an environment to encourage and support an ethos of wide-ranging...
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St. Louis, MO
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Birmingham, Alabama 35294
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Birmingham, AL
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300 Longwood Ave
Boston, Massachusetts 02115
(617) 355-6000
Boston Children's Hospital Boston Children's Hospital is a 395-bed comprehensive center for pediatric health care....
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Boston, MA
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Denver, Colorado 80291
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Denver, CO
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Rochester, Minnesota 55905
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Rochester, MN
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San Francisco, CA
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