Study to Evaluate the Efficacy and Safety of Three Different Doses of SCV 07 in Attenuating Oral Mucositis in Subjects With Head and Neck Cancer



Status:Archived
Conditions:Cancer, Dental
Therapuetic Areas:Dental / Maxillofacial Surgery, Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:December 2010
End Date:June 2012

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A Phase 2b, Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Three Different Doses of SCV 07 in Attenuating Oral Mucositis in Subjects With Head and Neck Cancer Receiving Concurrent Chemotherapy and Radiotherapy


This is a phase 2b, double-blind, placebo-controlled, 4-arm, adaptive-design trial,
initially stratified by cisplatin regimen, and then randomized 1:1:1:1. The study will be
conducted in subjects receiving ChemoRT for the treatment of squamous cell carcinomas (SCCs)
of the oral cavity, oropharynx, hypopharynx, or larynx. The study includes a treatment
period of approximately 7 weeks, depending on the subject's prescribed radiation plan, and
Week 1 and Week 4 post RT follow-up visits. It also includes a longer follow-up period of
approximately 12 months to determine if there is an effect of SCV 07 on the tumor response
to ChemoRT.



We found this trial at
32
sites
1 Medical Center Blvd
Winston-Salem, North Carolina 27103
(336) 716-2011
Wake Forest University Baptist Medical Center Welcome to Wake Forest Baptist Medical Center, a fully...
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621 West Lombard Street
Baltimore, Maryland 21201
(410) 706-7101
University of Maryland, Baltimore Welcome to the University of Maryland, Baltimore (UMB) founded in 1807...
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330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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Boston, MA
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3550 Jerome Avenue
Bronx, New York 10467
(718) 920-4321
Montefiore Medical Center As the academic medical center and University Hospital for Albert Einstein College...
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1853 West Polk Street
Chicago, Illinois 60612
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529 West Markham Street
Little Rock, Arkansas 72205
(501) 686-7000
University of Arkansas for Medical Sciences The University of Arkansas for Medical Sciences (UAMS) in...
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1514 Jefferson Highway
New Orleans, Louisiana 70121
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1 Brookings Drive
St. Louis, Missouri 63110
 (314) 935-5000
Washington University Washington University creates an environment to encourage and support an ethos of wide-ranging...
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110 Irving St NW # 3B28
Washington, Washington DC 20010
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Akron, Ohio 44304
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Baltimore, Maryland 21229
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Burlington, Maine 01805
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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Cookeville, Tennessee 38501
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Detroit, Michigan 48201
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Lexington, Kentucky 40536
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530 S Jackson St
Louisville, Kentucky 40202
502-562-3226
University of Louisville Hospital As the academic hospital at the heart of the Louisville Metro...
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8701 W Watertown Plank Rd
Milwaukee, Wisconsin
(414) 955-8296
Medical College of Wisconsin The Medical College (MCW) of Wisconsin is a major national research...
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333 Cedar St
New Haven, Connecticut 06504
(203) 432-4771
Yale University School of Medicine Founded in 1810, the Yale School of Medicine is a...
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270-05 76th Ave
New Hyde Park, New York 11040
(718) 470-7480
Long Island Jewish Medical Center Serving North Shore LIJ Health System employees and their families....
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Newark, Delaware 19713
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Norwalk, Connecticut 06856
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Oklahoma City, Oklahoma 73104
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3401 N Broad St
Philadelphia, Pennsylvania
(215) 707-2000
Temple University Hospital On January 18, 1892 a three-story house at 3403 North Broad Street...
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Pittsburgh, Pennsylvania 15240
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601 Elmwood Ave
Rochester, New York 14642
(585) 275-2100
Strong Memorial Hospital (University of Rochester School of Medicine) In addition to offering traditional and...
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1234 Napier Ave
St. Joseph, Michigan 49085
(269) 983-8300
Lakeland Regional Cancer Care Center - St. Joseph Since 1987, the Lakeland Cancer Care Center...
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1800 E Park Ave
State College, Pennsylvania 16803
(814) 231-7000
Mount Nittany Medical Center Mount Nittany Medical Center is a 260-bed acute care facility offering...
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Wheeling, West Virginia 26003
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