Open-label Long Term (52 Weeks) Safety and Tolerability of Agomelatine Sublingual Tablets in Major Depressive Disorder (MDD)



Status:Archived
Conditions:Depression, Major Depression Disorder (MDD)
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:June 2010

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Trial Summary
Trial Overview
Inclusion Criteria

A 52-week, Multi-center, Open-label Study of the Safety and Tolerability of Agomelatine Sublingual Tablets in Patients With Major Depressive Disorder (MDD)


The study will assess safety and tolerability of 0.5 mg/day and 1 mg/day of sublingual
(under the tongue) formulation of agomelatine in patients with Major Depressive Disorder
over a 52-week open-label phase.

Cohort I is restricted to include patients who have completed a previous Novartis
agomelatine (178C) Double-blind study.

Cohort II will include de-novo patients (those who did not participate in a previous
agomelatine 178C study) and will only be open for a limited time span ranging from
approximately June to Sept 2010, at which point this cohort II will be closed to enrollment.



We found this trial at
102
sites
Alexian Brothers Behavioral Health Hospital
Hoffman Estates, Illinois 60169
1706
mi
from 91732
Hoffman Estates, IL
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Emory University
201 Dowman Dr
Atlanta, Georgia 30303
(404) 727-6123
Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
1919
mi
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Atlanta, GA
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University of Alabama at Birmingham
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
1785
mi
from 91732
Birmingham, AL
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Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
2578
mi
from 91732
Boston, MA
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Montefiore Medical Center
3550 Jerome Avenue
Bronx, New York 10467
(718) 920-4321
Montefiore Medical Center As the academic medical center and University Hospital for Albert Einstein College...
2438
mi
from 91732
Bronx, NY
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University of Cincinnati Medical Center
234 Goodman Dr
Cincinnati, Ohio 45229
(513) 584-1000
University of Cincinnati Medical Center Opening in 1823 as the country
1878
mi
from 91732
Cincinnati, OH
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Northwest Clinical Research Center
1952 - 152nd Place NE
East Seattle, Washington 98007
425-453-0404
960
mi
from 91732
East Seattle, WA
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MD Clinical
911 E. Hallandale Beach Blvd
Hallandale Beach, Florida 33009
954-455-5757
2319
mi
from 91732
Hallandale Beach, FL
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Sunstone Medical Research, LLC
1904 East Barnett Road
Medford, Oregon 97504
541-973-2080
626
mi
from 91732
Medford, OR
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CRI Worldwide
16000 Horizon Way Mount
Mt Laurel, New Jersey 08054
856-533-5020
2386
mi
from 91732
Mt Laurel, NJ
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Alliance Research Group
3212 Cutshaw Ave
Richmond, Virginia 23230
804-353-4494
2266
mi
from 91732
Richmond, VA
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UCSF Helen Diller Family Comprehensive Cancer Center
1600 Divisadero Street
San Francisco, California 94115
888.689.8273
UCSF Helen Diller Family Comprehensive Cancer Center UCSF’s long tradition of excellence in cancer research...
356
mi
from 91732
San Francisco, CA
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Miami Research Associates
6141 Sunset Dr # 301
South Miami, Florida 33143
(305) 598-3125
Miami Research Associates Miami Research Associates (MRA) is the largest privately-owned multi-specialty clinical research center...
2318
mi
from 91732
South Miami, FL
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InSite Clinical Research
941 York Drive DeSoto
Southwest, Texas 75115
214-477-5162
1221
mi
from 91732
Southwest, TX
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Janus Center for Psychiatric Research
5601 Corporate Way
West Palm Beach, Florida 33407
561-238-3036
2301
mi
from 91732
West Palm Beach, FL
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Albuquerque Neuroscience Inc.
Albuquerque, New Mexico 87109
654
mi
from 91732
Albuquerque, NM
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Lehigh Center for Clinical Research
Allentown, Pennsylvania 18104
2353
mi
from 91732
Allentown, PA
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ICSL Clinical Studies
Altamonte Springs, Florida 32701
2181
mi
from 91732
Altamonte Springs, FL
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Millwood Hospital
Arlington, Texas 76011
1208
mi
from 91732
Arlington, TX
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Pharmasite Research
Baltimore, Maryland 21208
2295
mi
from 91732
Baltimore, MD
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Sheppard Pratt Health System
Baltimore, Maryland 21285
2302
mi
from 91732
Baltimore, MD
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Southwestern Research Institute
Beverly Hills, California 90210
22
mi
from 91732
Beverly Hills, CA
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Boston Clinical Trials, INC.
Boston, Massachusetts 02135
2578
mi
from 91732
Boston, MA
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University of Colorado, Boulder
Boulder, Colorado 80309
(303) 492-1411
University of Colorado, Boulder As the flagship university of the state of Colorado, CU-Boulder is...
810
mi
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Boulder, CO
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Florida Clinical Research Center, LLC
8043 Cooper Creek Boulevard Suite 107
Bradenton, Florida 34201
(941) 747-7900
Florida Clinical Research Center, LLC Led by Andrew J. Cutler, M.D., Florida Clinical Research Center,...
2143
mi
from 91732
Bradenton, FL
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Social Psychiatric Research Institute
Brooklyn, New York 11235
2436
mi
from 91732
Brooklyn, NY
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Neuro-Behavioral Cilnical Research Inc
Canton, Ohio 44718
2044
mi
from 91732
Canton, OH
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Neurobehavioral Research, Inc.
Cedarhurst, New York 11516
2447
mi
from 91732
Cedarhurst, NY
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Comprehensive NeuroScience
Cerritos, California 90703
14
mi
from 91732
Cerritos, CA
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Medical University of South Carolina
171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
2184
mi
from 91732
Charleston, SC
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Metro Health Medical Center
Cleveland, Ohio 44109
2031
mi
from 91732
Cleveland, OH
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North Star Medical Research
Cleveland, Ohio 44130
2027
mi
from 91732
Cleveland, OH
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Ohio State University
281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
1959
mi
from 91732
Columbus, OH
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Arocha Research Center
Coral Gables, Florida 33134
2318
mi
from 91732
Coral Gables, FL
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ATP Clinical Research, Inc.
Costa Mesa, California 92626
28
mi
from 91732
Costa Mesa, CA
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FutureSearch Clinical Trials, LP
Dallas, Texas 75231
1226
mi
from 91732
Dallas, TX
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Western Affiliated Research Institute
Denver, Colorado 80204
816
mi
from 91732
Denver, CO
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Michigan State University
East Lansing, Michigan 48824
1897
mi
from 91732
East Lansing, MI
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Alexian Brothers Neuroscience Institute
Elk Grove Village, Illinois 60007
1712
mi
from 91732
Elk Grove Village, IL
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Odyssey Research Services
Fargo, North Dakota 58104
1411
mi
from 91732
Fargo, ND
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SJS Clinical Research
Fort Walton Beach, Florida 32547
1843
mi
from 91732
Fort Walton Beach, FL
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Psychiatric Consultants
Franklin, Tennessee 37067
1763
mi
from 91732
Franklin, TN
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Collaborative Neuroscience Network
Garden Grove, California 92845
20
mi
from 91732
Garden Grove, CA
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Advanced Research Associates
Glendale, Arizona 85308
335
mi
from 91732
Glendale, AZ
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Pine Rest Christian Mental Health Services
Grand rapids, Michigan 49548
1838
mi
from 91732
Grand rapids, MI
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Pharmquest
Greensboro, North Carolina 27408
2150
mi
from 91732
Greensboro, NC
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Hawaii Clinical Research Center
Honolulu, Hawaii 96813
2572
mi
from 91732
Honolulu, HI
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Claghorn-Lesem Research Clinic
Houston, Texas 77008
1354
mi
from 91732
Houston, TX
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Bayou City Research Limited
Houston, Texas 77007
1355
mi
from 91732
Houston, TX
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Goldpoint Clinical Research
Indianapolis, Indiana 46260
1792
mi
from 91732
Indianapolis, IN
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Clinical Neuroscience Solution, Inc.
Jacksonville, Florida 32216
2135
mi
from 91732
Jacksonville, FL
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Joliet Center for Clinical Research
Joliet, Illinois 60435
1701
mi
from 91732
Joliet, IL
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Dynamic Clinical Research, Inc.
Kansas City, Missouri 64114
1339
mi
from 91732
Kansas City, MO
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Independent Clinical Researchers
Las Vegas, Nevada 89106
217
mi
from 91732
Las Vegas, NV
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Capstone Clinical Research
Libertyville, Illinois 60048
1717
mi
from 91732
Libertyville, IL
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Premier Psychiatry Group, LLC
Lincoln, Nebraska 68510
1256
mi
from 91732
Lincoln, NE
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Clinical Study Centers, LLC
Little Rock, Arkansas 72205
1460
mi
from 91732
Little Rock, AR
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Florida Clinical Research Center LLC
Maitland, Florida 32751
2183
mi
from 91732
Maitland, FL
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Suburban Research Associates
Media, Pennsylvania 19063
2363
mi
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Media, PA
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Research Strategies
Memphis, Tennessee 38119
1598
mi
from 91732
Memphis, TN
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Clinical Trials Management
Metairie, Louisiana 70006
1648
mi
from 91732
Metairie, LA
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Middlesex Hospital
Middletown, Connecticut 06457
2499
mi
from 91732
Middletown, CT
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Clinical Research Associates
Nashville, Tennessee 37203
1762
mi
from 91732
Nashville, TN
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UMDNJ-Robert Wood Johnson Medical Center
New Brunswick, New Jersey 08901
2410
mi
from 91732
New Brunswick, NJ
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Medical & Behavioral Health Research
New York, New York 10023
2433
mi
from 91732
New York, NY
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The Medical Research Network, LLC
New York, New York 10128
2435
mi
from 91732
New York, NY
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Eastside Comprehensive Medical Service
New York, New York 10021
2434
mi
from 91732
New York, NY
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Deaconess Clinic Gateway
Newburgh, Indiana 47630
1724
mi
from 91732
Newburgh, IN
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Pharmacology Research Institute
Newport Beach, California 92660
31
mi
from 91732
Newport Beach, CA
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Cutting Edge Research
Oklahoma City, Oklahoma 73116
1162
mi
from 91732
Oklahoma City, OK
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IPS Research
Oklahoma City, Oklahoma 73103
1165
mi
from 91732
Oklahoma City, OK
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Red River Medical Research
Oklahoma City, Oklahoma 73112
1161
mi
from 91732
Oklahoma City, OK
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SP Research, PLLC
Oklahoma City, Oklahoma 73112
1161
mi
from 91732
Oklahoma City, OK
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Pacific Clinical Research Medical Group
Orange, California 92868
21
mi
from 91732
Orange, CA
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Uc Irvine Medical Center
Orange, California 92868
21
mi
from 91732
Orange, CA
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CNS Healthcare
Orlando, Florida 32806
2185
mi
from 91732
Orlando, FL
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CRI Worldwide, LLC
Philadelphia, Pennsylvania 19139
2371
mi
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Philadelphia, PA
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Southwest Health Ltd
Phoenix, Arizona 85254
349
mi
from 91732
Phoenix, AZ
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CNS Clinical Research
Pompano Beach, Florida 33067
2305
mi
from 91732
Pompano Beach, FL
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Quantum Lab. at N. Broward Memory Disorder Center
Pompano Beach, Florida 33064
2312
mi
from 91732
Pompano Beach, FL
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Oregon Center for Clinical Investigations, Inc.
Portland, Oregon 97210
829
mi
from 91732
Portland, OR
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Summit Research Network
Portland, Oregon 97210
829
mi
from 91732
Portland, OR
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Zarzar Psychiatric Associates, PLLC
Raleigh, North Carolina 27607
2214
mi
from 91732
Raleigh, NC
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VCU Medical Center
1250 E. Marshall St.
Richmond, Virginia 23298
(804) 828-9000
Virginia Commonwealth University Medical Center The Virginia Commonwealth University Health System is an urban, comprehensive...
2269
mi
from 91732
Richmond, VA
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Rochester Center for Behavioral Medicine
Rochester Hills, Michigan 48307
1964
mi
from 91732
Rochester Hills, MI
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Northwest Behavioral Research Center
Roswell, Georgia 30076
1919
mi
from 91732
Roswell, GA
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Radiant Research
Salt Lake City, Utah 84107
565
mi
from 91732
Salt Lake City, UT
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University Of Utah Hospital
Salt Lake City, Utah 84132
573
mi
from 91732
Salt Lake City, UT
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California Neuropsychopharmacology Clinical Research Institute (CNRI)
San Diego, California 92102
106
mi
from 91732
San Diego, CA
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Neuropsychiatric Research Center of Orange County
Santa Ana, California 92701
24
mi
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Santa Ana, CA
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Rush University - Psychiatric Medicine Associates
Skokie, Illinois 60076
1726
mi
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Skokie, IL
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Frontier Institute
Spokane, Washington 99204
938
mi
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Spokane, WA
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Neurology Clinic of St. Cloud
St. Cloud, Minnesota 56303
1484
mi
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St. Cloud, MN
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Comprehensive NeuroScience, Inc.
St. Petersburg, Florida 33716
2127
mi
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St. Petersburg, FL
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Richmond Behavioral Associates
Staten Island, New York 10312
2424
mi
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Staten Island, NY
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Viking Clinical Research
Temecula, California 92591
63
mi
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Temecula, CA
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BioBehavioral Health
Toms River, New Jersey 08755
2426
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Toms River, NJ
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Collaborative Neuroscience Network, INC
Torrance, California 90502
22
mi
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Torrance, CA
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Brighton Research Group, LLC
Virginia Beach, Virginia 23452
2348
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Virginia Beach, VA
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Coastal Research Associates
Weymouth, Massachusetts 02190
2585
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Weymouth, MA
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Grayline Clinical Drug Trials
Wichita Falls, Texas 76309
1114
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Wichita Falls, TX
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