Hospital of the University of Pennsylvania
3400 Spruce St
Philadelphia, Pennsylvania 19104
 (215) 662-4000 http://www.pennmedicine.org/hospital-university-pennsylvania/

Use our guide to learn which trials are right for you!

The Hospital of the University of Pennsylvania (HUP) is world-renowned for its clinical and research excellence, forging the way for newer and better ways to diagnose and treat illnesses and disorders. Its long and rich history of top-notch patient care began more than two centuries ago with the founding of the nation's first medical school, the University of Pennsylvania. Since 1765 when it first opened its doors, Penn has been dedicated to the training of physicians and the discovery and implementation of new medical knowledge.

The world-class faculty and staff of the Hospital of the University of Pennsylvania are dedicated to superior patient care, education and research for a better, healthier future. Their significant and groundbreaking contributions to medicine are recognized both nationally and internationally. The interdisciplinary team of professionals provides personalized care and service to patients — all within a compassionate and respectful environment. Innovative research coupled with responsive, hands-on care allows Penn to tailor treatment specifically to individual patient needs.

We've found
149 trials
at this facility
Immunology / Infectious Diseases, Reproductive Clinical Trial
Human Papillomavirus (HPV) Infection in Pregnancy
Status: Enrolling
Updated: 6/20/2007
mi
from
Philadelphia, PA
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Acute Myeloid Leukemia Clinical Trial
Efficacy Study of Oral Sapacitabine to Treat Acute Myeloid Leukemia in Elderly Patients
Status: Enrolling, Phase II
Updated: 11/7/2011
mi
from
Philadelphia, PA
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Prostate Cancer Clinical Trial
Studying Repeated DCE-MRI and DWI in Patients Diagnosed With Prostate Cancer
Status: Enrolling, Phase I
Updated: 1/25/2013
mi
from
Philadelphia, PA
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PreTerm Birth Clinical Trial
Motherhood and Microbiome
Status: Enrolling
Updated: 4/6/2015
mi
from
Philadelphia, PA
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Bone Alteration PE Clinical Trial
Micromechanical Modeling Using Low Magnitude Mechanical Stimulation
Status: Enrolling, Phase II
Updated: 12/23/2014
mi
from
Philadelphia, PA
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Oncology Clinical Trial
DC Vaccine for Patients With Ductal Carcinoma In Situ
Status: Enrolling, Phase I, II
Updated: 2/11/2014
mi
from
Philadelphia, PA
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Neurology Clinical Trial
Connected Health Blood Pressure Monitoring In Stroke and TIA Patients
Status: Enrolling
Updated: 12/23/2015
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
COAPT Clinical Trial
Status: Enrolling, Phase III
Updated: 2/10/2016
mi
from
Philadelphia, PA
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Colorectal Cancer Metastatic Clinical Trial
Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer
Status: Enrolling, Phase III
Updated: 2/16/2016
mi
from
Philadelphia, PA
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Nephrology / Urology, Other Clinical Trial
Eculizumab for Prevention of Delayed Graft Function (DGF) in Kidney Transplantation
Status: Enrolling, Phase II
Updated: 2/17/2016
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221
Status: Enrolling
Updated: 2/25/2016
mi
from
Philadelphia, PA
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Aneurysm of Aortic Arch Clinical Trial
Early Feasibility of the Branched TAG® Device in the Treatment of Aortic Arch Aneurysms
Status: Enrolling
Updated: 2/29/2016
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System
Status: Enrolling, Phase III
Updated: 3/29/2016
mi
from
Philadelphia, PA
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Spinal Cord Injury Clinical Trial
Riluzole in Spinal Cord Injury Study
Status: Enrolling, Phase II, III
Updated: 4/1/2016
mi
from
Philadelphia, PA
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Pulmonary Embolism Clinical Trial
Cook IVC Filter Study
Status: Enrolling
Updated: 4/1/2016
mi
from
Philadelphia, PA
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Primary Systemic (AL) Amyloidosis Clinical Trial
The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis
Status: Enrolling, Phase III
Updated: 4/1/2016
mi
from
Philadelphia, PA
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Descending Thoracic Aortic Aneurysm Clinical Trial
Zenith TX2® Post-market Approval Study
Status: Enrolling
Updated: 9/10/2014
mi
from
Philadelphia, PA
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Painful Joint Prostheses Clinical Trial
FDG-PET Imaging in Painful Joint Prosthesis
Status: Enrolling
Updated: 8/22/2006
mi
from
Philadelphia, PA
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Primary Amyloidosis Clinical Trial
Phase I/2, Open Label, Dose Escalation Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis
Status: Enrolling, Phase I, II
Updated: 5/14/2015
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
S-ICD® System Post Approval Study
Status: Enrolling
Updated: 11/18/2015
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Intraoperative Folate-fluorescein Conjugate (EC17) Lung Cancer (CA)
Status: Enrolling, Phase I
Updated: 10/29/2015
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Intraoperative Imaging of Breast Cancer With Indocyanine Green
Status: Enrolling, Phase
Updated: 12/3/2015
mi
from
Philadelphia, PA
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Endocrinology, Neurology Clinical Trial
Study of Procoagulation Markers in Stroke Patients
Status: Enrolling
Updated: 8/24/2015
mi
from
Philadelphia, PA
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Heart Failure Clinical Trial
Quadripolar Pacing Post Approval Study
Status: Enrolling
Updated: 9/4/2013
mi
from
Philadelphia, PA
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Ovarian Cancer Clinical Trial
EC17 for Intraoperative Imaging in Occult Ovarian Cancer
Status: Enrolling, Phase I
Updated: 12/3/2015
mi
from
Philadelphia, PA
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Reproductive Clinical Trial
Prevention of Preterm Birth With a Pessary in Twin Gestations
Status: Enrolling
Updated: 6/17/2015
mi
from
Philadelphia, PA
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Severe Symptomatic Calcified Native Aortic Valve Stenosis Clinical Trial
Cerebral Protection in Transcatheter Aortic Valve Replacement
Status: Enrolling
Updated: 2/2/2015
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Zenith® Low Profile AAA Endovascular Graft
Status: Enrolling
Updated: 9/3/2015
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from
Philadelphia, PA
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PreTerm Birth Clinical Trial
Maternal Gut Microbiome (MGM) Study of Diet, the Gut Microbiome and Preterm Birth
Status: Enrolling
Updated: 9/24/2015
mi
from
Philadelphia, PA
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Secondary Malignant Neoplasm of Vertebral Column Clinical Trial
The Epidemiology, Process and Outcomes of Spine Oncology (EPOSO)
Status: Enrolling
Updated: 1/13/2016
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve
Status: Enrolling
Updated: 1/21/2016
mi
from
Philadelphia, PA
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Peripheral Nerve Discontinuities Clinical Trial
Comparison of Processed Nerve Allograft and Collagen Nerve Cuffs for Peripheral Nerve Repair
Status: Enrolling, Phase III
Updated: 1/24/2016
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
An Intervention to Improve Implantable Cardioverter-Defibrillator Deactivation Conversations
Status: Enrolling
Updated: 1/26/2016
mi
from
Philadelphia, PA
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Clinical Trial
A Study of Symptoms and Quality of Life in Patients With Implantable Cardiac Defibrillators (ICDs) and Their Caregivers
Status: Enrolling
Updated: 1/26/2016
mi
from
Philadelphia, PA
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Progressive Supranuclear Palsy Clinical Trial
Extension Study of BMS-986168 in Patients With Progressive Supranuclear Palsy Who Participated in CN002003
Status: Enrolling, Phase I
Updated: 2/17/2016
mi
from
Philadelphia, PA
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Glomerular Disease Clinical Trial
Vitamin D Supplementation in Glomerular Disease
Status: Enrolling
Updated: 2/29/2016
mi
from
Philadelphia, PA
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Aortic Aneurysm, Thoracic Clinical Trial
Feasibility Study for GORE® TAG® Thoracic Branch Endoprosthesis to Treat Proximal Descending Thoracic Aortic Aneurysms
Status: Enrolling
Updated: 2/29/2016
mi
from
Philadelphia, PA
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Pain Clinical Trial
Study of Pain Control With Hormonal IUS Insertion
Status: Enrolling, Phase IV
Updated: 3/9/2016
mi
from
Philadelphia, PA
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Cardiovascular Disease Clinical Trial
Cardiovascular Inflammation Reduction Trial
Status: Enrolling, Phase III
Updated: 3/15/2016
mi
from
Philadelphia, PA
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Hepatocellular Carcinoma Clinical Trial
HepaSphere/Quadrasphere Microspheres for Delivery of Doxorubicin for the Treatment of Hepatocellular Cancer
Status: Enrolling, Phase III
Updated: 3/16/2016
mi
from
Philadelphia, PA
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Clinical Trial
Expulsion of Immediate Postplacental Copper Intrauterine Devices at Six Months: A Prospective Cohort Study
Status: Enrolling
Updated: 3/17/2016
mi
from
Philadelphia, PA
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Advanced Refractory Left Ventricular Heart Failure Clinical Trial
MOMENTUM 3 IDE Clinical Study Protocol
Status: Enrolling
Updated: 3/24/2016
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
SPYRAL HTN-OFF MED Study
Status: Enrolling, Phase II
Updated: 4/1/2016
mi
from
Philadelphia, PA
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Carotid Stenosis Clinical Trial
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
Status: Enrolling
Updated: 4/5/2016
mi
from
Philadelphia, PA
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Progressive Supranuclear Palsy Clinical Trial
Multiple Ascending Dose Study of Intravenously Administered BMS-986168 in Patients With Progressive Supranuclear Palsy
Status: Enrolling, Phase I
Updated: 4/5/2016
mi
from
Philadelphia, PA
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Heart Failure Clinical Trial
Longitudinal Surveillance Registry (LSR) of ACUITY Spiral
Status: Enrolling, Phase IV
Updated: 11/10/2015
mi
from
Philadelphia, PA
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Paroxysmal Atrial Fibrillation Clinical Trial
NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Drug Refractory Recurrent Symptomatic Paroxysmal Atrial Fibrillation
Status: Enrolling, Phase IV
Updated: 3/21/2012
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases, Neurology Clinical Trial
Carotid Stenting vs. Surgery of Severe Carotid Artery Disease and Stroke Prevention in Asymptomatic Patients (ACT I)
Status: Enrolling
Updated: 8/30/2012
mi
from
Philadelphia, PA
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Hematology, Oncology, Other Clinical Trial
Expanded Access Program of Ponatinib
Status: Enrolling
Updated: 11/14/2012
mi
from
Philadelphia, PA
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Breast Cancer Clinical Trial
Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery
Status: Enrolling, Phase III
Updated: 12/19/2013
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Post-Myocardial Infarction Remodeling Prevention Therapy
Status: Enrolling
Updated: 8/20/2013
mi
from
Philadelphia, PA
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Hemophilia B Clinical Trial
A Safety and Efficacy Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia B
Status: Enrolling, Phase II, III
Updated: 12/19/2013
mi
from
Philadelphia, PA
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Metastatic Breast Cancer Clinical Trial
Palbociclib (PD-0332991) Combined With Fulvestrant In Hormone Receptor+ HER2-Negative Metastatic Breast Cancer After Endocrine Failure (PALOMA-3)
Status: Enrolling, Phase III
Updated: 4/10/2014
mi
from
Philadelphia, PA
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PreTerm Birth Clinical Trial
CellulaR Injury and Preterm Birth
Status: Enrolling
Updated: 12/22/2015
mi
from
Philadelphia, PA
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mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS)
Status: Enrolling
Updated: 8/20/2015
mi
from
Philadelphia, PA
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Stroke Clinical Trial
Non-invasive Measurement of Cerebral Dynamic Autoregulation
Status: Enrolling
Updated: 12/23/2015
mi
from
Philadelphia, PA
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Preeclampsia Clinical Trial
The Study of Cardiovascular Outcomes in Women With Preeclampsia Using Echocardiography: The SCOPE Study
Status: Enrolling
Updated: 10/16/2015
mi
from
Philadelphia, PA
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Clinical Trial
Handoffs and Transitions in Critical Care
Status: Enrolling
Updated: 10/2/2015
mi
from
Philadelphia, PA
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Parainfluenza Clinical Trial
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Examine the Effects of DAS181 in Immunocompromised Subjects With Lower Respiratory Tract Parainfluenza Infection on Supplemental Oxygen
Status: Enrolling, Phase II
Updated: 2/17/2016
mi
from
Philadelphia, PA
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Aortic Aneurysm Abdominal Clinical Trial
Zenith® p-Branch® Endovascular Graft Pivotal Study
Status: Enrolling
Updated: 3/8/2016
mi
from
Philadelphia, PA
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Oncology, Psychiatry / Psychology, Reproductive Clinical Trial
Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer
Status: Enrolling
Updated: 3/10/2016
mi
from
Philadelphia, PA
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Immunology / Infectious Diseases Clinical Trial
Reducing Proviral HIV DNA With Interferon-a
Status: Enrolling, Phase II
Updated: 3/14/2016
mi
from
Philadelphia, PA
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Left Sided Heart Failure Clinical Trial
A Prospective, Single Arm, Multi-Center Clinical Study in Collaboration With the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS®) to Evaluate the Thoracotomy Implant Technique of the HeartWare HVAD® System in Patients With Advanced Heart Failure
Status: Enrolling
Updated: 3/22/2016
mi
from
Philadelphia, PA
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Hypertension, Portal Clinical Trial
Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis
Status: Enrolling, Phase II
Updated: 3/24/2016
mi
from
Philadelphia, PA
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Hematology Clinical Trial
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia
Status: Enrolling, Phase III
Updated: 3/30/2016
mi
from
Philadelphia, PA
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Heart Failure Clinical Trial
Confirmation Trial of the Acorn CorCap Cardiac Support Device (CSD) at the Same Time as Mitral Valve Repair
Status: Enrolling, Phase II
Updated: 6/16/2009
mi
from
Philadelphia, PA
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Immunology / Infectious Diseases, Ophthalmology Clinical Trial
Longitudinal Study of Ocular Complications of AIDS (LSOCA)
Status: Enrolling
Updated: 6/23/2005
mi
from
Philadelphia, PA
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Diabetic Foot Disease Clinical Trial
FDG-PET Imaging in Complicated Diabetic Foot
Status: Enrolling
Updated: 8/22/2006
mi
from
Philadelphia, PA
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Patients With Typical Aflutter and Manifest Risk Factors With Future Development of AF Clinical Trial
Pulmonary Vein Isolation To Reduce Future Risk Of Atrial Fibrillation In Patients Undergoing Typical Flutter
Status: Enrolling
Updated: 10/30/2013
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Freedom SOLO Stentless Heart Valve Study
Status: Enrolling
Updated: 3/11/2013
mi
from
Philadelphia, PA
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Aortic Aneurysm, Abdominal Clinical Trial
Zenith® p-Branch® OTS Multicenter Study
Status: Enrolling
Updated: 3/3/2015
mi
from
Philadelphia, PA
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Renal Cell Carcinoma Clinical Trial
Intraoperative Imagery of Renal Nodules With Folate-fluorescein Conjugate(EC17)
Status: Enrolling, Phase
Updated: 12/3/2015
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases, Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Respicardia, Inc. Pivotal Trial of the remedē System
Status: Enrolling
Updated: 4/14/2015
mi
from
Philadelphia, PA
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Musculoskeletal, Pharmacology / Toxicology, Reproductive Clinical Trial
Screening To Obviate Preterm Birth
Status: Enrolling
Updated: 1/2/2014
mi
from
Philadelphia, PA
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Nephrolithiasis Clinical Trial
Tamsulosin for Urolithiasis in the Emergency Dept
Status: Enrolling, Phase IV
Updated: 7/22/2013
mi
from
Philadelphia, PA
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Benzodiazepine Refractory Status Epilepticus Clinical Trial
Established Status Epilepticus Treatment Trial
Status: Enrolling, Phase III
Updated: 10/30/2015
mi
from
Philadelphia, PA
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Resectable Breast Cancer Clinical Trial
Intraoperative Imagery of Breast Cancer With Folate-FITC (EC17)
Status: Enrolling, Phase I
Updated: 12/3/2015
mi
from
Philadelphia, PA
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Persistent Atrial Fibrillation Clinical Trial
Evaluation of the Phased Radio Frequency Ablation System
Status: Enrolling, Phase III
Updated: 12/3/2015
mi
from
Philadelphia, PA
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Immunology / Infectious Diseases, Nephrology / Urology, Other Clinical Trial
Short-course Methenamine Hippurate for Prevention of Post-operative UTI
Status: Enrolling
Updated: 2/6/2015
mi
from
Philadelphia, PA
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Intracranial Aneurysm Clinical Trial
Neuroform ATLAS IDE Study
Status: Enrolling
Updated: 12/9/2015
mi
from
Philadelphia, PA
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Neoplasms Clinical Trial
Intraoperative Imaging of Pulmonary Nodules by OTL38
Status: Enrolling, Phase I
Updated: 11/9/2015
mi
from
Philadelphia, PA
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Aortic Valve Stenosis Clinical Trial
Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial
Status: Enrolling
Updated: 10/8/2015
mi
from
Philadelphia, PA
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Neurology Clinical Trial
Improving Coordination and Transitions of Care in Stroke Patients
Status: Enrolling, Phase III
Updated: 12/24/2015
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
CPR Education Via a Mobile Application Compared to VSI Kit
Status: Enrolling
Updated: 2/25/2016
mi
from
Philadelphia, PA
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Hemophilia B Clinical Trial
A Safety and Efficacy Extension Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia B
Status: Enrolling, Phase III
Updated: 3/8/2016
mi
from
Philadelphia, PA
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High Frequency Sensorineural Hearing Loss Clinical Trial
Hybrid L24 New Enrollment Post Approval Study
Status: Enrolling
Updated: 3/16/2016
mi
from
Philadelphia, PA
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Mitral Valve Regurgitation (Degenerative or Functional) Clinical Trial
Edwards Lifesciences CardiAQ™ Transcatheter Mitral Valve Replacement (TMVR) Early Feasibility Study
Status: Enrolling, Phase I
Updated: 3/18/2016
mi
from
Philadelphia, PA
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Liver Cirrhosis, Biliary Clinical Trial
Phase 3 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cirrhosis
Status: Enrolling, Phase III
Updated: 4/1/2016
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
SPYRAL HTN-ON MED Study
Status: Enrolling, Phase II
Updated: 4/1/2016
mi
from
Philadelphia, PA
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AL Amyloidosis Clinical Trial
The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis
Status: Enrolling, Phase II
Updated: 4/1/2016
mi
from
Philadelphia, PA
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Hematology Clinical Trial
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome
Status: Enrolling, Phase I
Updated: 12/30/2015
mi
from
Philadelphia, PA
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Abdominal Aortic Aneurysm Clinical Trial
Safety and Effectiveness Trial of the Ventana Fenestrated Stent Graft System
Status: Enrolling
Updated: 10/3/2012
mi
from
Philadelphia, PA
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Cutaneous Lupus Erythematosus Clinical Trial
Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus
Status: Enrolling
Updated: 7/20/2012
mi
from
Philadelphia, PA
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Heart Failure Clinical Trial
CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary Bypass
Status: Enrolling
Updated: 5/14/2013
mi
from
Philadelphia, PA
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Endocrinology, Neurology Clinical Trial
Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial
Status: Enrolling, Phase III
Updated: 12/1/2014
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
PRESERVE-Zenith® Iliac Branch Clinical Study
Status: Enrolling
Updated: 9/29/2014
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)
Status: Enrolling
Updated: 11/3/2015
mi
from
Philadelphia, PA
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Acute Tibial Fracture Requiring Intramedullary Nailing Clinical Trial
T1Rho MRI Evaluation of Patellofemoral Changes After Tibial IM Nailing
Status: Enrolling
Updated: 5/20/2015
mi
from
Philadelphia, PA
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Reproductive Clinical Trial
Prevention of Preterm Birth With a Pessary in Singleton Gestations
Status: Enrolling
Updated: 6/17/2015
mi
from
Philadelphia, PA
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