Barbara Ann Karmanos Cancer Institute
Karmanos is based in southeast Michigan, in midtown Detroit, and is one of 41 National Cancer Institute-designated Comprehensive Cancer Centers in the United States. In fact, Karmanos is the only hospital in Michigan dedicated exclusively to fighting cancer.
Caring for more than 6,000 new patients annually and conducting more than 700 cancer-specific scientific investigation programs and clinical trials, the Karmanos Cancer Center is among the nation’s best cancer centers. Karmanos offers access to more than 100 cancer treatments that no other local hospital has.
Through the commitment of 1,000 staff, including nearly 300 faculty members, and supported by thousands of volunteer and financial donors, Karmanos strives to prevent, detect and eradicate cancer. Our long-term partnership with the WSU School of Medicine enhances the collaboration of critical research and academics related to cancer care.
We've found
80 trials
at this facility
Oncology, Reproductive Clinical Trial
Updated: 8/2/2012
ChemoFx® PRO - A Post-Market Data Collection Study
Status: Enrolling
Updated: 8/2/2012
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 11/19/2012
FAU in Treating Patients With Advanced Solid Tumors or Lymphoma
Status: Enrolling
Updated: 11/19/2012
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Leukemia Clinical Trial
Updated: 7/24/2014
Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: Enrolling,
Phase
III
Updated: 7/24/2014
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Myeloid Leukemia, Chronic, Chronic Phase Clinical Trial
Updated: 12/31/1969
Ponatinib in Participants With Resistant Chronic Phase Chronic Myeloid Leukemia (CP-CML) to Characterize the Efficacy and Safety of a Range of Doses
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Hematology, Neurology Clinical Trial
Updated: 12/31/1969
Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Graft vs Host Disease Clinical Trial
Updated: 12/31/1969
Study of PRO 140 for Prophylaxis of Acute GVHD in Patients Undergoing RIC Allogenic Stem-Cell Transplantaton
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Prostate Cancer Clinical Trial
Updated: 12/31/1969
Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Non-Small Cell Lung Cancer Clinical Trial
Updated: 12/31/1969
Pembrolizumab in Combination With Platinum-based Doublet Chemotherapy in Patients With EGFR Mutation and ALK Positive NSCLC (Non-Small Cell Lung Cancer) With Progressive Disease Following Prior Tyrosine Kinase Inhibitors (TKIs)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Advanced Solid Neoplasm Clinical Trial
Updated: 12/31/1969
A Study to Evaluate the Effects of Rifampin on Pharmacokinetics (PK) of Pevonedistat in Participants With Advanced Solid Tumors
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Cancer Clinical Trial
Updated: 12/31/1969
A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Colorectal Cancer Clinical Trial
Updated: 11/18/2013
NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
Status: Enrolling,
Phase
II, III
Updated: 11/18/2013
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Hematology, Oncology Clinical Trial
Updated: 12/31/1969
3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Cancer Clinical Trial
Updated: 5/30/2012
Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced Cancer
Status: Enrolling
Updated: 5/30/2012
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Oncology Clinical Trial
Updated: 9/23/2013
RO4929097 and Vismodegib in Treating Patients With Breast Cancer That is Metastatic or Cannot Be Removed By Surgery
Status: Enrolling,
Phase
I
Updated: 9/23/2013
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Acute Lymphoblastic Leukemia (ALL) Clinical Trial
Updated: 7/17/2014
A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL
Status: Enrolling,
Phase
III
Updated: 7/17/2014
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Advanced Solid Tumor Clinical Trial
Updated: 12/12/2012
MSC2015103B in Solid Tumors
Status: Enrolling
Updated: 12/12/2012
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Hematologic Neoplasms Clinical Trial
Updated: 12/31/1969
Safety Study of Anti-LAG-3 in Relapsed or Refractory Hematologic Malignancies
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Leukemia, Myeloid, Acute Clinical Trial
Updated: 12/31/1969
Dose Escalation Study of JNJ-63709178, a Humanized CD123 x CD3 DuoBody in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Sickle Cell Disease Clinical Trial
Updated: 4/30/2018
Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)
Status: Enrolling,
Phase
II
Updated: 4/30/2018
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Lymphoma Clinical Trial
Updated: 12/31/1969
Safety and Efficacy Study of RP4010, in Patients With Relapsed or Refractory Lymphomas
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Graft-versus-host Disease (GVHD) Clinical Trial
Updated: 12/31/1969
GRAVITAS-301: A Study of Itacitinib or Placebo in Combination With Corticosteroids for Treatment of Acute Graft-Versus-Host Disease
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Metastatic Melanoma Clinical Trial
Updated: 12/31/1969
A Study of IMO-2125 in Combination With Ipilimumab Versus Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma (ILLUMINATE-301)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Clinical Trial
Updated: 12/31/1969
Nivolumab and Radiation Therapy in Treating Patients With Localized/Locally Advanced Urothelial Bladder Cancer Ineligible for Chemotherapy
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Feasibility and Utilization of an Application-based Question Prompt List
Status: Enrolling
Updated: 12/31/1969
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Cervical Cancer Clinical Trial
Updated: 12/31/1969
Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of TAK-981 in Adult Participants With Metastatic Solid Tumors or Lymphomas.
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Neuroblastoma Clinical Trial
Updated: 4/5/2011
Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma
Status: Enrolling
Updated: 4/5/2011
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Oncology Clinical Trial
Updated: 12/31/1969
Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 6/10/2015
Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer That is Stage III-IV, Refractory, or Recurrent
Status: Enrolling,
Phase
I
Updated: 6/10/2015
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Advanced Cutaneous Squamous Cell Carcinoma Clinical Trial
Updated: 12/31/1969
Study of REGN2810 in Patients With Advanced Cutaneous Squamous Cell Carcinoma
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Relapsed or Refractory Follicular Lymphoma, Relapsed or Refractory Diffuse Large B-Cell Lymphoma Clinical Trial
Updated: 12/31/1969
A Study of Obinutuzumab, Polatuzumab Vedotin, and Lenalidomide in Relapsed or Refractory Follicular Lymphoma (FL) and Rituximab in Combination With Polatuzumab Vedotin and Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Chronic Graft Versus Host Disease Clinical Trial
Updated: 12/31/1969
Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Subjects With New Onset cGVHD
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Hematology, Oncology Clinical Trial
Updated: 12/31/1969
Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Squamous Cell Carcinoma of the Head and Neck Clinical Trial
Updated: 12/31/1969
Study of LN-145 Autologous Tumor Infiltrating Lymphocytes in the Treatment of Squamous Cell Carcinoma of the Head & Neck
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Hematology, Oncology Clinical Trial
Updated: 12/31/1969
A Trial of TTI-622 in Patients With Advanced Relapsed or Refractory Lymphoma or Myeloma
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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ALK-positive Advanced NSCLC Clinical Trial
Updated: 12/31/1969
A Study of Brigatinib in Participants With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or Ceritinib
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Advanced or Metastatic Solid Tumor Clinical Trial
Updated: 12/31/1969
Phase 1 Study of the Combination of Rogaratinib With Copanlisib in Patients With Fibroblast Growth Factor Receptor (FGFR)-Positive, Locally Advanced or Metastatic Solid Tumors
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Cancer Clinical Trial
Updated: 12/31/1969
MyPatientPal: An App to Help Patients Manage Their Cancer Care
Status: Enrolling
Updated: 12/31/1969
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Breast Cancer Clinical Trial
Updated: 12/31/1969
Reducing Metabolic Syndrome Among Breast Cancer Survivors
Status: Enrolling
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 2/6/2009
Cryotherapy in Treating Patients With Primary Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery
Status: Enrolling
Updated: 2/6/2009
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Breast Cancer Clinical Trial
Updated: 9/20/2012
Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer
Status: Enrolling
Updated: 9/20/2012
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Cancer Clinical Trial
Updated: 8/30/2012
Collecting Tumor Samples From Patients With Gynecological Tumors
Status: Enrolling
Updated: 8/30/2012
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Advanced Solid Tumors Clinical Trial
Updated: 5/31/2012
Study of Intravenous TCD-717 in Patients With Advanced Solid Tumors
Status: Enrolling,
Phase
I
Updated: 5/31/2012
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Oncology Clinical Trial
Updated: 11/19/2015
PROCLAIM Registry to Evaluate the Treatment Patterns and Clinical Response in Malignancy
Status: Enrolling
Updated: 11/19/2015
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Breast Cancer Clinical Trial
Updated: 12/6/2012
Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer
Status: Enrolling,
Phase
II
Updated: 12/6/2012
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Oncology Clinical Trial
Updated: 2/11/2016
Selinexor, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Metastatic Pancreatic Cancer
Status: Enrolling,
Phase
I, II
Updated: 2/11/2016
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Relapsed/Refractory Mantle Cell Lymphoma Clinical Trial
Updated: 12/31/1969
A Phase 2 Multicenter Study Evaluating Subjects With Relapsed/Refractory Mantle Cell Lymphoma
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Prostatic Neoplasms Clinical Trial
Updated: 12/31/1969
An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Anemia, Sickle Cell Clinical Trial
Updated: 12/31/1969
STRIDE Biorepository
Status: Enrolling,
Phase
Updated: 12/31/1969
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Head and Neck Neoplasms Clinical Trial
Updated: 12/31/1969
Study of Pembrolizumab (MK-3475) or Placebo With Chemoradiation in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-412/KEYNOTE-412)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Hematology, Oncology Clinical Trial
Updated: 12/31/1969
Selinexor Plus Combination Chemotherapy in Treating Patients With Advanced B Cell Non-Hodgkin Lymphoma
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Non-small Cell Lung Cancer Adenocarcinoma Clinical Trial
Updated: 12/31/1969
Grapiprant (ARY-007) and Pembrolizumab in Patients With Advanced or Metastatic Post-PD-1/L1 NSCLC Adenocarcinoma
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Kidney Cancer Clinical Trial
Updated: 1/9/2014
Bevacizumab and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer
Status: Enrolling,
Phase
II
Updated: 1/9/2014
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Hematology, Oncology, Orthopedics / Podiatry Clinical Trial
Updated: 8/3/2012
Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission
Status: Enrolling
Updated: 8/3/2012
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
Updated: 4/18/2013
Biomarkers to Detect Mesothelioma Early in Patients Exposed to Asbestos or Vermiculite
Status: Enrolling
Updated: 4/18/2013
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Prostate Cancer Clinical Trial
Updated: 12/30/2011
Bicalutamide and Goserelin or Leuprolide Acetate With or Without Cixutumumab in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer
Status: Enrolling
Updated: 12/30/2011
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Metastatic Melanoma Clinical Trial
Updated: 5/29/2014
HD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic Melanoma
Status: Enrolling,
Phase
IV
Updated: 5/29/2014
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Metastatic Castration-resistant Prostate Cancer Clinical Trial
Updated: 4/4/2013
Provide Expanded Access to MDV3100 and Monitor Its Safety in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Status: Enrolling
Updated: 4/4/2013
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Breast Cancer Clinical Trial
Updated: 12/31/1969
Ultrasound Tomography Using SoftVue in Diagnosing Women With Breast Cancer
Status: Enrolling
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 2/8/2016
Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancer
Status: Enrolling,
Phase
I
Updated: 2/8/2016
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Hematology, Oncology Clinical Trial
Updated: 12/31/1969
MMRF Molecular Profiling Protocol
Status: Enrolling,
Phase
Updated: 12/31/1969
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Mantle-Cell Lymphoma Clinical Trial
Updated: 12/31/1969
Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Amyloidosis Clinical Trial
Updated: 12/31/1969
A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Urothelial Carcinoma Clinical Trial
Updated: 12/31/1969
Phase 1b/2 Study of Rogaratinib (BAY1163877) in Combination With Atezolizumab in Urothelial Carcinoma
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Multiple Myeloma Clinical Trial
Updated: 12/31/1969
A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-Cell Maturation Antigen (BCMA) in Participants With Relapsed or Refractory Multiple Myeloma
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
A Trial of PT2977 in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Cancer Survivors Clinical Trial
Updated: 12/31/1969
C.A.P.A.B.L.E. (CrossFit and Physical Activity: A Better Life Experience Study)
Status: Enrolling
Updated: 12/31/1969
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Chronic Graft-Versus-Host-Disease Clinical Trial
Updated: 12/31/1969
Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
A Dose Escalation Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 2/6/2014
Phase Ib/II Study Evaluating Orteronel (Without Prednisone) Combined With Itraconazole In Men With Castration-Resistant Prostate Cancer (CRPC)
Status: Upcoming,
Phase
I, II
Updated: 2/6/2014
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/31/1969
Home Sleep Apnea Machine in Evaluating Obstructive Sleep Apnea in Patients With Stage III-IV Head and Neck Cancer
Status: Upcoming
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 8/11/2015
EGFRBi-Armed Autologous T Cells in Treating Patients With Recurrent or Refractory Glioblastoma
Status: Upcoming,
Phase
I, II
Updated: 8/11/2015
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Metastatic Prostate Cancer Clinical Trial
Updated: 12/31/1969
A Study to Determine Frequency of DNA-repair Defects in Men With Metastatic Prostate Cancer
Status: Upcoming,
Phase
Updated: 12/31/1969
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