Pilot-Tart Cherry, Mitral Transcriptome, and POAF Incidence



Status:Recruiting
Conditions:Atrial Fibrillation
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:50 - 79
Updated:2/14/2019
Start Date:February 8, 2019
End Date:December 30, 2021
Contact:Nicole Shuler, RN
Email:gervais@med.umich.edu
Phone:734-232-4297

Use our guide to learn which trials are right for you!

Pilot-Tart Cherry, Mitral Transcriptome and POAF Incidence

Assess impact of Tart Cherry Concentrate in cardiac surgical patients on POAF and related
clinical and economic outcomes. Measure inflammation gene transcripts in cardiac tissue.


Inclusion Criteria:

1. Males and female patients (age 50-79) at the Mitral Valve Clinic/CVC undergoing
elective cardiac surgery for mitral valve repair without the Cox MAZE procedure (MVR
patients also undergoing CABG and/or tricuspid valve repair are also eligible)

2. In sinus rhythm (no pre-operative atrial fibrillation, no hx of AF)

Exclusion Criteria:

1. Age ≥ 80 years

2. Diagnosed pre-operative chronic or paroxysmal AF

3. Prior ablation procedure for AF

4. Previous cardiac surgery

5. Implanted pacemaker

6. Active smoker

7. Comorbidities such as congenital or cardiac re-operation

8. Use of antiarrhythmic agents

9. Active inflammatory or infectious disease or malignancy

10. Diagnosed autoimmune disease

11. Corticosteroid or other immunomodulatory or immunosuppressive medication

12. Known sensitivity to sorbitol

13. Known gastric sensitivity to acidic juices like orange juice
We found this trial at
1
site
500 S State St
Ann Arbor, Michigan 48109
(734) 764-1817
Phone: 734-232-4297
University of Michigan The University of Michigan was founded in 1817 as one of the...
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials