Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome



Status:Recruiting
Conditions:Other Indications, Ocular
Therapuetic Areas:Ophthalmology, Other
Healthy:No
Age Range:Any - 18
Updated:12/20/2018
Start Date:May 30, 2018
End Date:June 2020
Contact:Niklaus H Mueller
Email:niklaus.mueller@ucdenver.edu
Phone:3037249995

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria
This study involves the collection ocular lens tissue from individuals with Down syndrome and
age-matched controls at the time of cataract surgery.

Individuals with Down syndrome have an increased rate of cataract. The reason for this
increase is unclear. Normally, once cataracts become a significant impairment, an
ophthalmologist will determine when cataract surgery should be performed. When this surgery
is performed, cataractous tissues are cut out and discarded with medical waste. In this
study, these tissue will be collected and protein analysis performed to determine what
changes in different proteins are found in Down syndrome lenses as compared to normal
cataractous lenses.

Inclusion Criteria:

- Undergoing cataract surgery for lens extraction.

Exclusion Criteria:

- Known genetic cause other than Down syndrome causing cataract.
We found this trial at
1
site
Children's Hospital Colorado
13123 E 16th Ave
Aurora, Colorado 80045
(720) 777-1234
Phone: 303-724-9995
Children's Hospital Colorado At Children's Hospital Colorado, we see more, treat more and heal more...
?
mi
from
Aurora, CO
Click here to add this to my saved trials