Computerized Cognitive Training for Patients With Epilepsy



Status:Not yet recruiting
Conditions:Neurology, Epilepsy
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:18 - 55
Updated:4/6/2019
Start Date:June 2019
End Date:December 2020
Contact:Kayla Whearty
Email:Kayla.Whearty@nyumc.org
Phone:646 558 0809

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This is a study on the effectiveness of computerized cognitive training for treatment of
memory disorders in patients with epilepsy. Participants will be recruited from patients
referred for neuropsychological assessment through the NYU Comprehensive Epilepsy Center's
inpatient and outpatient services. Individuals meeting inclusion criteria will be screened
for the presence of memory disturbance (defined by results of neuropsychological testing) and
lack of exposure to any previous form of computerized cognitive training. All eligible
subjects will be provided with an account for Lumosity with instructions to complete training
modules 5 days per week for a total of 8 consecutive weeks. Outcomes will be evaluated
through changes on the neuropsychological test battery.


Inclusion Criteria:

- Documented diagnosis of epilepsy based on medical records. The records will be
reviewed by the PI and the approved study personnel to confirm that a diagnosis of
epilepsy has been made.

- Presence of memory disturbance, as defined by an immediate or delayed memory index
score < 85 on the Repeatable Battery for the Assessment of Neuropsychological Status
(RBANS)

- Availability of a home computer and internet for access to the computer training
program.

Exclusion Criteria:

- Full Scale IQ < 80, as assessed by an appropriate Wechsler scale (WAIS-IV or WASI-II).

- Epilepsy surgery within 8 weeks of the beginning of the trial.

- History of chronic progressive neurologic or neurodegenerative illnesses (e.g.,
Alzheimer's disease, multiple sclerosis, primary or metastatic malignancy). Patients
with headache or migraine are not excluded.

- History of Axis I psychiatric illness with psychotic features. (e.g., schizophrenia or
bipolar disorder). Patients with depression or anxiety (treated or untreated) without
psychotic features are not excluded.

- Visual or auditory impairment, which precludes participation in part, or all of the
testing or computer training.

- English as a first language will not be required, but participants must have either
received some of their schooling in English or used English in their work for >10
years.

- Previous exposure (> one week) to Lumosity or a similar computerized training program.
We found this trial at
1
site
550 1st Ave
New York, New York 10016
(212) 263-7300
Principal Investigator: William Barr, MD
Phone: 646-558-0809
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