Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD)



Status:Recruiting
Conditions:Depression, Depression, Major Depression Disorder (MDD)
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 75
Updated:3/23/2019
Start Date:August 2, 2018
End Date:July 3, 2021
Contact:Clinical Trial Registry Team
Email:IR-CTRegistration@Allergan.com
Phone:877-277-8566

Use our guide to learn which trials are right for you!

A Randomized, Double-blind, Placebo-controlled, Multi-center Study of Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder

The study will evaluate the efficacy, safety, and tolerability of 450 milligrams (mg) or 225
mg of Rapastinel compared to placebo in the prevention of relapse in participants with major
depressive disorder (MDD).


Inclusion Criteria: -

- Completion of Study RAP-MD-30, RAP-MD-31, or RAP-MD-32

- If female of childbearing potential, have a negative serum β-human chorionic
gonadotropin (β-hCG) pregnancy test

Exclusion Criteria: -

- DSM-5-based diagnosis of any disorder other than MDD that was the primary focus of
treatment within 6 months before Visit 1

- Lifetime history of meeting DSM-5 criteria for:

- 1.Schizophrenia spectrum or other psychotic disorder

- 2.Bipolar or related disorder

- 3.Major neurocognitive disorder

- 4.Neurodevelopmental disorder of greater than mild severity or of a severity that
impacts the participant's ability to consent, follow study directions, or otherwise
safely participate in the study

- 5.Dissociative disorder

- 6.Posttraumatic stress disorder

- 7.MDD with psychotic features

- Significant suicide risk, as judged by the Investigator
We found this trial at
42
sites
Media, Pennsylvania 19063
Phone: 610-891-9024
?
mi
from
Media, PA
Click here to add this to my saved trials
Anaheim, California 92804
Phone: 714-484-4904
?
mi
from
Anaheim, CA
Click here to add this to my saved trials
3015 Flowers Road South
Atlanta, Georgia 30341
Phone: 770-817-9200
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
811 Juniper St NE
Atlanta, Georgia 30308
(404) 881-5800
Phone: 404-881-5800
Atlanta Center for Medical Research Welcome to the Atlanta Center for Medical Research, a leader...
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Austin, Texas 78737
Phone: 512-898-9362
?
mi
from
Austin, TX
Click here to add this to my saved trials
Baltimore, Maryland 21208
Phone: 410-602-1440
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Bellevue, Washington 98007
Phone: 425-453-0404
?
mi
from
Bellevue, WA
Click here to add this to my saved trials
Berlin, New Jersey
Phone: 856-753-7335
?
mi
from
Berlin, NJ
Click here to add this to my saved trials
Boston, Massachusetts 02135
Phone: 617-477-4868
?
mi
from
Boston, MA
Click here to add this to my saved trials
?
mi
from
Burgas,
Click here to add this to my saved trials
Charlotte, North Carolina 28204
Phone: 980-209-9784
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Creve Coeur, Missouri 63141
Phone: 314-298-0001
?
mi
from
Creve Coeur, MO
Click here to add this to my saved trials
Dayton, Ohio 45408
Phone: 937-424-1050
?
mi
from
Dayton, OH
Click here to add this to my saved trials
Decatur, Georgia 30030
Phone: 404-537-1281
?
mi
from
Decatur, GA
Click here to add this to my saved trials
Flowood, Mississippi 39232
Phone: 601-420-5810
?
mi
from
Flowood, MS
Click here to add this to my saved trials
Gaithersburg, Maryland 20877
Phone: 301-251-4702
?
mi
from
Gaithersburg, MD
Click here to add this to my saved trials
Garden Grove, California 92845
Phone: 714-799-7799
?
mi
from
Garden Grove, CA
Click here to add this to my saved trials
Hoffman Estates, Illinois 60169
Phone: 847-230-3958
?
mi
from
Hoffman Estates, IL
Click here to add this to my saved trials
7261 Sheridan Street
Hollywood, Florida 33024
Phone: 954-990-7649
?
mi
from
Hollywood, FL
Click here to add this to my saved trials
Jacksonville, Florida 32256
Phone: 904-281-5757
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Las Vegas, Nevada 89102
Phone: 760-758-2222
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Lauderhill, Florida 33319
Phone: 954-990-6326
?
mi
from
Lauderhill, FL
Click here to add this to my saved trials
Libertyville, Illinois 60048
Phone: 847-549-7214
?
mi
from
Libertyville, IL
Click here to add this to my saved trials
Little Rock, Arkansas 72211
Phone: 501-221-8681
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
1801 Coral Way
Miami, Florida 33133
Phone: 305-856-9778
?
mi
from
Miami, FL
Click here to add this to my saved trials
Mount Kisco, New York 10549
Phone: 914-385-0200
?
mi
from
Mount Kisco, NY
Click here to add this to my saved trials
1908 Sweetwater Road
National City, California 91950
Phone: 619-327-0155
?
mi
from
National City, CA
Click here to add this to my saved trials
New York, New York 10021
Phone: 212-288-0138
?
mi
from
New York, NY
Click here to add this to my saved trials
New York, New York 10128
Phone: 212-595-5012
?
mi
from
New York, NY
Click here to add this to my saved trials
1428 Madison Ave
New York, New York 10029
(212) 241-6500
Icahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai is...
?
mi
from
New York, NY
Click here to add this to my saved trials
Norristown, Pennsylvania 19403
Phone: 610-277-8073
?
mi
from
Norristown, PA
Click here to add this to my saved trials
Oceanside, California 92056
Phone: 760-758-2222
?
mi
from
Oceanside, CA
Click here to add this to my saved trials
Oklahoma City, Oklahoma 73103
Phone: 405-235-8188
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Orange, California 92868
Phone: 714-289-1100
?
mi
from
Orange, CA
Click here to add this to my saved trials
Phoenix, Arizona 85012
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Rochester, New York 14618
Phone: 585-241-9670
?
mi
from
Rochester, NY
Click here to add this to my saved trials
San Diego, California 92123
Phone: 858-278-3647
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Sherman Oaks, California 91403
Phone: 818-990-2671
?
mi
from
Sherman Oaks, CA
Click here to add this to my saved trials
Smyrna, Georgia 30080
Phone: 770-319-8025
?
mi
from
Smyrna, GA
Click here to add this to my saved trials
Temecula, California 92591
Phone: 951-695-6238
?
mi
from
Temecula, CA
Click here to add this to my saved trials
Upland, California 91786
Phone: 909-920-3000
?
mi
from
Upland, CA
Click here to add this to my saved trials
521 Mount Auburn Street
Watertown, Massachusetts 02472
Phone: 617-744-8542
?
mi
from
Watertown, MA
Click here to add this to my saved trials