A Study to Assess if Mirikizumab is Effective and Safe Compared to Secukinumab and Placebo in Moderate to Severe Plaque Psoriasis (OASIS-2)
| Status: | Recruiting |
|---|---|
| Conditions: | Psoriasis |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/5/2019 |
| Start Date: | June 26, 2018 |
| End Date: | December 11, 2020 |
| Contact: | There may be multiple sites in this clinical trial. 1-877-CTLILLY |
| Email: | ClinicalTrials.gov@lilly.com |
| Phone: | 1-317-615-4559 |
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Comparing the Efficacy and Safety of Mirikizumab to Secukinumab and Placebo in Patients With Moderate-to-Severe Plaque Psoriasis OASIS-2
The reason for this study is to see how effective and safe mirikizumab is compared to
secukinumab and placebo for moderate to severe plaque psoriasis.
secukinumab and placebo for moderate to severe plaque psoriasis.
Inclusion Criteria:
- Participant must have chronic plaque psoriasis for at least 6 months.
Exclusion Criteria:
- Participant must not be breastfeeding or nursing woman.
- Participant must not have had serious, opportunistic, or chronic/recurring infection
within 3 months.
- Participant must not have received a Bacillus Calmette-Guerin (BCG) vaccination within
12 months or received live vaccine(s) (including attenuated live vaccines) within 12
weeks of baseline or intend to receive either during the study.
- Participant must not have any other skin conditions (excluding psoriasis).
- Participant must not have previous exposure to Cosentyx and any other biologic therapy
targeting IL-17 (including Taltz).
- Participant must not have received anti-tumor necrosis factor (TNF) biologics within 8
weeks.
- Participant must not have previous exposure to any biologic therapy targeting IL-23
(including Stelara).
We found this trial at
48
sites
Click here to add this to my saved trials
1720 2nd Ave S
Birmingham, Alabama 35233
Birmingham, Alabama 35233
(205) 934-4011
Principal Investigator: Boni Elizabeth Elewski
Phone: 2055029960
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
Click here to add this to my saved trials
59 One Mile Road
East Windsor, New Jersey 08520
East Windsor, New Jersey 08520
609-443-4500
Principal Investigator: Jerry Bagel
Click here to add this to my saved trials
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Principal Investigator: Alex Ortega Loayza
Phone: 503-494-4770
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
Click here to add this to my saved trials
Click here to add this to my saved trials
Austin, Texas 78660
Principal Investigator: Aron Jeffrey Gewirtzman
Click here to add this to my saved trials
Bakersfield, California 99309
Principal Investigator: Jeffrey James Crowley
Phone: 6613273756
Click here to add this to my saved trials
Baton Rouge, Louisiana 70806
Principal Investigator: Ira Hughes Thorla
Phone: 2259275663
Click here to add this to my saved trials
Beverly Hills, California 90212
Principal Investigator: David M Stoll
Phone: 310-273-6033
Click here to add this to my saved trials
Bexley, Ohio 43209
Principal Investigator: Matthew Zirwas
Phone: 614-725-1716
Click here to add this to my saved trials
6051 North Eagle Road
Boise, Idaho 83713
Boise, Idaho 83713
Principal Investigator: Ryan Harris
Phone: 208-467-3006
Click here to add this to my saved trials
Caba, Buenos Aires
Principal Investigator: Nora Noemi Kogan
Phone: 541148238701
Click here to add this to my saved trials
Cary, North Carolina 27518
Principal Investigator: Catherine Hren
Phone: 919-342-3447
Click here to add this to my saved trials
410 Market Street
Chapel Hill, North Carolina 27516
Chapel Hill, North Carolina 27516
Principal Investigator: Aida Lugo-Somolinos
Phone: 984-974-3672
Click here to add this to my saved trials
Cleveland, Ohio 44012
Principal Investigator: Neil J Korman
Phone: 216-844-3178
Click here to add this to my saved trials
Dallas, Texas 75231
Principal Investigator: Jennifer A Cather
Phone: 214-361-2008
Click here to add this to my saved trials
Darien, Illinois 60561
Principal Investigator: Vassilios A Dimitropoulos
Phone: 630-920-1900
Click here to add this to my saved trials
Encinitas, California 92024
Principal Investigator: Stacy R. Smith
Phone: 760-203-3839
Click here to add this to my saved trials
725 University Boulevard
Fairborn, Ohio 45324
Fairborn, Ohio 45324
Principal Investigator: Jeffrey Travers
Phone: 937-775-2463
Click here to add this to my saved trials
17271 Brookhurst Street
Fountain Valley, California 92708
Fountain Valley, California 92708
Principal Investigator: Vivian Laquer
Phone: 714-531-2966
Click here to add this to my saved trials
Indianapolis, Indiana 46256
Principal Investigator: Scott A Fretzin
Phone: 317-621-7731
Click here to add this to my saved trials
Johnston, Rhode Island 02919
Principal Investigator: Ellen H Frankel
Phone: 401-454-3800
Click here to add this to my saved trials
Los Angeles, California 90033
Principal Investigator: Stefani Takahashi
Phone: 323-865-3641
Click here to add this to my saved trials
Louisville, Kentucky 40202
Principal Investigator: Cindy E Owen
Phone: 502-585-9059
Click here to add this to my saved trials
Macon, Georgia 31217
Principal Investigator: David J Cohen
Phone: 478-742-2180
Click here to add this to my saved trials
New York, New York 10029
Principal Investigator: Mark G. Lebwohl
Phone: 212-241-3288
Click here to add this to my saved trials
Click here to add this to my saved trials
Newport Beach, California 92660
Principal Investigator: Navid Nami
Phone: 949-720-1170
Click here to add this to my saved trials
Norfolk, Virginia 23507
Principal Investigator: David M Pariser
Phone: 757-622-6315
Click here to add this to my saved trials
Orange Park, Florida 32073
Principal Investigator: George Schmieder
Phone: 904-458-0411
Click here to add this to my saved trials
Click here to add this to my saved trials
Pflugerville, Texas 78660
Principal Investigator: Edward Lain
Phone: 512-279-2545
Click here to add this to my saved trials
Plainfield, Indiana 46168
Principal Investigator: Scott T Guenthner
Phone: 317-837-6082
Click here to add this to my saved trials
Portland, Oregon 97210
Principal Investigator: Phoebe Rich
Phone: 503-226-3376
Click here to add this to my saved trials
Rockville, Maryland 20850
Principal Investigator: Benjamin N. Lockshin
Phone: 301-355-3183
Click here to add this to my saved trials
Rockville, Maryland 20850
Principal Investigator: Lawrence Green
Phone: 301-610-0663
Click here to add this to my saved trials
5301 Keystone Court
Rolling Meadows, Illinois 60008
Rolling Meadows, Illinois 60008
Principal Investigator: Michael Bukhalo
Phone: 847-392-5440
Click here to add this to my saved trials
Saint Louis, Missouri 63117
Principal Investigator: Craig L Leonardi
Phone: 314-721-5565
Click here to add this to my saved trials
San Antonio, Texas 78218
Principal Investigator: John C. Browning
Phone: 210-829-5180
Click here to add this to my saved trials
San Antonio, Texas 78249
Principal Investigator: William Cragun
Phone: 210-614-2662
Click here to add this to my saved trials
15 Santa Rosa Street
San Luis Obispo, California 93405
San Luis Obispo, California 93405
Principal Investigator: Michael Heffernan
Phone: 805-541-2650
Click here to add this to my saved trials
Santa Monica, California 90404
Principal Investigator: Paul S Yamauchi
Phone: 310-828-8887
Click here to add this to my saved trials
Savannah, Georgia 31406
Principal Investigator: Corinne Howington
Phone: 912-443-4253
Click here to add this to my saved trials
Seattle, Washington 98101
Principal Investigator: Peter J Jenkin
Phone: 206-315-0377
Click here to add this to my saved trials
211 North Eddy St.
South Bend, Indiana 46617
South Bend, Indiana 46617
574-234-8161
Principal Investigator: Holly Hake Harris
Phone: 574-204-6432
South Bend Clinic The South Bend Clinic employs a staff of 610 at its five...
Click here to add this to my saved trials
Webster, Texas 77598
Principal Investigator: Patricia C. Lee
Phone: 281-333-2288
Click here to add this to my saved trials
West Jordan, Utah 84088
Principal Investigator: Douglass W Forsha
Phone: 801-316-0266
Click here to add this to my saved trials
1907 Tradd Ct
Wilmington, North Carolina 28401
Wilmington, North Carolina 28401
(910) 799-5500
Principal Investigator: James E Appel
Phone: 910-799-5500
PMG Research of Wilmington PMG Research of Wilmington has two offices situated in a 1...
Click here to add this to my saved trials