The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial



Status:Recruiting
Conditions:Hospital
Therapuetic Areas:Other
Healthy:No
Age Range:18 - Any
Updated:3/16/2019
Start Date:September 12, 2018
End Date:March 30, 2020
Contact:Bobby Warren, MPS
Email:bobby.warren@duke.edu
Phone:9196817957

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The objective of this study is to implement an opt-out protocol to guide appropriate
de-escalation of antibiotics in qualifying patients. The protocol, determined over the course
a year with the help of a large, well-rounded expert panel, will be used by pharmacists to
recommend de-escalation of antibiotics to hospital providers. Providers can then decide
whether or not to follow the recommendation in determining the best treatment pathway for his
or her patient.


Inclusion Criteria:

- Blood culture preliminary results that indicate no growth as of 48-96 hours.
(Exception: Patients with a single positive blood culture for coagulase negative
Staphylococcus and no central line in place will also be included).

- Still on broad spectrum antibiotic therapy after 48-96 hours.

Exclusion Criteria:

- Adult patients who are located in ICU wards.
We found this trial at
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Boston, Massachusetts 02138
Principal Investigator: Michael Klompas, MD
Phone: 617-867-4991
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Durham, North Carolina 27710
(919) 684-8111
Phone: 919-681-7957
Duke University Younger than most other prestigious U.S. research universities, Duke University consistently ranks among...
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3400 Spruce St
Philadelphia, Pennsylvania 19104
 (215) 662-4000
Principal Investigator: Michael David, MD, PhD
Hospital of the University of Pennsylvania The Hospital of the University of Pennsylvania (HUP) is...
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Atlanta, Georgia 30309
Phone: 404-558-8873
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1255 Hwy 54 W,
Fayetteville, Georgia 30214
(770) 719-7000
Phone: 770-719-7000
Piedmont Fayette Hospital Piedmont Fayette Hospital, a 172-bed community hospital, is among the most highly-ranked...
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Lumberton, North Carolina 28359
Phone: 910-671-5175
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Newnan, Georgia 30265
Phone: 770-400-2450
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Philadelphia, Pennsylvania 19104
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Statesville, North Carolina 28677
Phone: 704-878-4599
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Wilson, North Carolina 27893
Phone: 252-399-8341
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Wilson, NC
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