Safety of Transarterial Chemoembolization (TACE) in the Setting of an Elevated Bilirubin



Status:Recruiting
Conditions:Liver Cancer, Cancer, Gastrointestinal
Therapuetic Areas:Gastroenterology, Oncology
Healthy:No
Age Range:18 - Any
Updated:4/28/2018
Start Date:January 2, 2018
End Date:January 2020
Contact:Shamar J Young, MD
Email:youn1862@umn.edu
Phone:612-626-5388

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Safety of Transarterial Chemoembolization in Patients With Elevated Bilirubin

The aim of this study is to evaluate the safety of selective transarterial chemoembolization
(TACE) of hepatocellular carcinoma (HCC) in the setting of an elevated total bilirubin, but
relatively normal direct bilirubin.


Inclusion Criteria:

- hepatocellular carcinoma (HCC)

- Direct or conjugated bilirubin < 3 mg/dl

- Total bilirubin > 3 mg/dl

- Willing and able to provide informed consent

- >18 years of age

Exclusion Criteria:

- Currently pregnant

- Patients who are surgical or ablation candidates as determined by multidisciplinary
hepatobiliary tumor conference.

- Arterial anatomy which would preclude selective transarterial chemoembolization

- Patients who have a INR or platelet count which are not correctable to <1.8 and
>35,000 respectively

- Patients with extrahepatic metastases

- Patients with portal vein invasion
We found this trial at
1
site
Minneapolis, Minnesota 55455
(612) 625-5000
Principal Investigator: Shamar Young, MD
Phone: 612-624-6904
Univ of Minnesota With a flagship campus in the heart of the Twin Cities, and...
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Minneapolis, MN
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