Functional Resistance Training to Improve Knee Function After ACL Reconstruction



Status:Recruiting
Conditions:Orthopedic
Therapuetic Areas:Orthopedics / Podiatry
Healthy:No
Age Range:14 - 40
Updated:3/16/2019
Start Date:March 17, 2018
End Date:November 2020
Contact:Riann M Palmieri-Smith, PhD
Email:riannp@umich.edu
Phone:734-615-3154

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Functional Resistance Training During Gait: A Novel Intervention to Improve Knee Knee Function After ACL Reconstruction

The purpose of this study is to examine if thigh muscle weakness and the lack of muscle
activation that accompanies ACL injury and reconstruction can be improved with functional
resistance training.

Profound quadriceps weakness is ubiquitous after anterior cruciate ligament (ACL)
reconstruction, and current rehabilitation approaches are not successful in optimizing
quadriceps strength and knee function even years after the surgery. We hypothesize that
suboptimal strength and functional outcomes after ACL surgery are due to the lack of
task-specific exercise elements during strength training. This application seeks to assess
whether progressive functional resistance training during gait will significantly improve
quadriceps function, neural excitability, and knee mechanics during gait. The proposed
studies will not only lay the foundation for a novel training paradigm, but will also improve
our understanding of the mechanisms mediating neuromuscular and biomechanical changes after
functional resistance training.

Inclusion Criteria:

- aged 14-40 years

- suffered an acute, complete ACL rupture

- willingness to participate in testing and follow-up as outlined in the protocol

- English-speaking

Exclusion Criteria:

- inability to provide written informed consent

- female subjects who are pregnant or are planning to become pregnant

- previous ACL injury

- previous surgery to either knee

- bony fracture accompanying ACL injury

- patients who experienced a knee dislocation;

- patients who are contraindicated for transcranial magnetic stimulation (e.g., metal
implants in head, unexplained recurrent headaches, history of seizures, epileptogenic
drugs, active psychiatric illness, etc.).
We found this trial at
1
site
500 S State St
Ann Arbor, Michigan 48109
(734) 764-1817
Phone: 734-615-3154
University of Michigan The University of Michigan was founded in 1817 as one of the...
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Ann Arbor, MI
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