Biomarker Study for Heart Failure in Children With Single Ventricle Physiology
| Status: | Archived |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
Identification of Biomarkers for Heart Failure in Children With Single Ventricle Physiology
The purpose of this study is to determine if children with heart disease where there is only
one pumping chamber("ventricle") have proteins (biomarkers") in the blood that can be used
to monitor the function of their heart.
We will investigate whether levels of blood proteins in children with well-functioning
hearts with one ("single") ventricle are similar to levels of these blood proteins in
children with two ventricles. For children with hearts with a single ventricle, we will
examine blood proteins at various levels of heart function. To assess blood protein levels,
we will collect small (6 mL) samples of blood. Heart function will be determined by existing
clinical scoring systems. Enrolled patients will receive an echocardiogram, which is a
dynamic ultrasound picture of the beating heart.
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