A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:40 - 55
Updated:10/20/2018
Start Date:May 26, 2016
End Date:October 31, 2017

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A Phase 2, Multicenter, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety, Efficacy, and Pharmacokinetics of the Fixed Combination of AGN-199201 and AGN-190584 in Patients With Presbyopia

This is a safety, efficacy and pharmacokinetics study of the fixed combination of AGN-199201
and AGN-190584 in participants with presbyopia (inability to focus on items close-up).


Inclusion Criteria:

- Normal vision at distance, either natural or post corneal laser refractive surgery,
with presbyopia in each eye and complaints of poor near vision that impacts activities
of daily living

Exclusion Criteria:

- Use of any topical ophthalmic medications, including artificial tears other than the
study medications during the study

- Corneal abnormalities in either eye that interfere with visual acuity

- History of cataract surgery, phakic intraocular lens surgery, corneal inlay surgery or
any intraocular surgery

- Diagnosis of glaucoma or ocular hypertension.
We found this trial at
25
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3133 Southwest 32nd Avenue
Ocala, Florida 34474
748
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Ocala, FL
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301 University Blvd
Galveston, Texas 77555
(409) 772-1011
University of Texas Medical Branch Established in 1891 as the University of Texas Medical Department,...
992
mi
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Galveston, TX
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301 West Huntington Drive
Arcadia, California 91007
1959
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Arcadia, CA
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Artesia, California 90701
1968
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Artesia, CA
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1 Village Square
Baltimore, Maryland 21210
341
mi
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Baltimore, MD
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
524
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Charleston, SC
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Cranberry Township, Pennsylvania 16066
161
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Cranberry Township, PA
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Cypress, California 90630
1967
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Cypress, CA
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1514
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Draper, UT
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El Paso, Texas 79902
1425
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El Paso, TX
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Glendale, California 91203
1970
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Glendale, CA
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Glendale, California 91205
1969
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Glendale, CA
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Louisville, Kentucky 40206
188
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Louisville, KY
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Louisville, Kentucky 40206
185
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Louisville, KY
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Memphis, Tennessee
508
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Memphis, TN
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Miami, Florida 33143
996
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Miami, FL
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Morrow, Georgia 30260
446
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Morrow, GA
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Newport Beach, California
1967
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Newport Beach, CA
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Palo Alto, California 94303
2097
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Palo Alto, CA
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Portland, Oregon 97210
2026
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Portland, OR
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San Antonio, Texas 78229
1138
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San Antonio, TX
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San Antonio, Texas 78240
1138
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Sarasota, Florida 34239
872
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Sarasota, FL
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23600 Telo Avenue
Torrance, California 90505
1983
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Torrance, CA
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Winston-Salem, North Carolina 27101
307
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Winston-Salem, NC
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