Open-Label Influenza Vaccine Evaluation
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Influenza |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 65 - 74 |
| Updated: | 7/19/2018 |
| Start Date: | September 2016 |
| End Date: | September 2018 |
Open-Label, Randomized Study of Immune Response to Licensed Influenza Vaccines in Adults 65-74 Years of Age (US Flu Vaccine Effectiveness Serologic Study, 2016-17 and 2017-18)
This is an open-label, randomized trial in up to 210 adults aged 65-74 years to evaluate the
immune response to consecutive influenza vaccination across 2 seasons. Participants will be
randomized to receive 1 of 3 licensed and recommended vaccines in the first year; 2 arms will
receive the same vaccination in the second year and the third arm will be randomized again to
1 of 3 licensed vaccines. All participants will have pre and post-vaccination serum blood
draws for a total of 6 draws over 18 months.
immune response to consecutive influenza vaccination across 2 seasons. Participants will be
randomized to receive 1 of 3 licensed and recommended vaccines in the first year; 2 arms will
receive the same vaccination in the second year and the third arm will be randomized again to
1 of 3 licensed vaccines. All participants will have pre and post-vaccination serum blood
draws for a total of 6 draws over 18 months.
Inclusion Criteria:
- Age 65-74 years at the time of study enrollment and are ambulatory and live in
selected Wisconsin community or surrounding communities.
- Willing and able to give informed consent prior to study enrollment
- Able to comply with study requirements.
Exclusion Criteria:
- Prior receipt of 2016-17 influenza vaccine
- Current participation in another clinical trial
- Presence of a contraindication to influenza vaccine
We found this trial at
1
site
Marshfield Clinic - Marshfield Center The Clinic was incorporated under Wisconsin law in 1916 and...
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