Strategic MAnagement to Optimize Response To Cardiac Resynchronization Therapy Registry

Inclusion Criteria:

- Subject implanted or upgraded with a NG3 or NG4 CRT-D device connected with any
manufacturer quadripolar LV lead based on BSC labeling for devices in specific
geographies.

- Subjects must be enrolled between 1 and 21 calendar days post CRT-D implantation
procedure.

- Subject is age 18 or above, or of legal age to give informed consent specific to each
country and national laws

- Subject is willing and capable of complying with follow-up visits and procedures as
defined by this protocol

Exclusion Criteria:

- Subject with documented life expectancy of less than 12 months

- Subject currently on the active heart transplant list or has a current Left
Ventricular Assist Device or other assist device (mechanical circulatory support
device).

- Subject who have had a pre-existing CRT device

- Subject enrolled in any other concurrent clinical trial without prior written approval
from BSC Clinical Trial Manager

- Women of childbearing potential who are or might be pregnant at time of study
enrolment

- Any contra-indication to receive a CRT-D device per local guidelines