An Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced Cancers
Status: | Recruiting |
---|---|
Conditions: | Lung Cancer, Cancer |
Therapuetic Areas: | Oncology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 12/16/2018 |
Start Date: | September 14, 2016 |
End Date: | November 17, 2021 |
Contact: | Recruiting sites have contact information. Please contact the sites directly. If there is no contact information, please email: |
Email: | Clinical.Trials@bms.com |
A Phase 3b/4 Safety Trial of Flat Dose Nivolumab In Combination With Ipilimumab in Participants With Non-Small Cell Lung Cancer
A study to evaluate the safety of Nivolumab given in combination with Ipilimumab in patients
with advanced cancers. The initial group will enroll patients with newly diagnosed Stage 4 or
non-small cell lung cancer that has come back.
with advanced cancers. The initial group will enroll patients with newly diagnosed Stage 4 or
non-small cell lung cancer that has come back.
For more information regarding Bristol-Myers Squibb Clinical Trial participation, please
visit www.BMSStudyConnect.com
Inclusion Criteria:
- Histologically confirmed Stage 4 or recurrent non-small cell lung cancer
- Eastern Cooperative Oncology Group (ECOG) score 0-1 (Physically able to carry out
light housework or office work through to being fully active as you were before
cancer)
- No prior systemic anticancer therapy (including EGFR and ALK inhibitors)
- Tissue or Programmed death-ligand 1 (PD-L1) results available
Cohort 1A Inclusion Criteria:
- Eastern Cooperative Oncology Group (ECOG) score 2 or
- Eastern Cooperative Oncology Group (ECOG) score 0-1 and one disease specific criteria
as listed in the protocol
Cohort C Inclusion Criteria:
- High Tumor Mutation Burden
Exclusion Criteria:
- Untreated brain metastases
- An active malignancy that requires concurrent intervention
- Active, known or suspected autoimmune disease
- Carcinomatous meningitis, which means there is inflammation of the covering of the
brain, caused by cancer
Other protocol defined inclusion/exclusion criteria could apply
We found this trial at
71
sites
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529 West Markham Street
Little Rock, Arkansas 72205
Little Rock, Arkansas 72205
(501) 686-7000
![University of Arkansas for Medical Sciences](/wp-content/uploads/logos/university-of-arkansas-for-medical-sciences.jpg)
Phone: 501-686-8274
University of Arkansas for Medical Sciences The University of Arkansas for Medical Sciences (UAMS) in...
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220 S Palisade Dr # 204
Santa Maria, California 93454
Santa Maria, California 93454
Phone: 310-206-0179
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1000 Johnson Ferry Rd NE
Atlanta, Georgia 30342
Atlanta, Georgia 30342
(404) 851-8000
![Northside Hospital](/wp-content/uploads/logos/northside-hospital.jpg)
Phone: 770-496-9457
Northside Hospital Northside Hospital-Atlanta (in Sandy Springs) opened in 1970. The original facility had 250...
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Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
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MetroHealth Med Ctr The MetroHealth System is one of the largest, most comprehensive health care...
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Providence Regional Cancer Partnership Founded in 2007, the Providence Regional Cancer Partnership is the result...
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8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
Fairfax, Virginia 22031
(703) 280-5390
![Virginia Cancer Specialists, PC](/wp-content/uploads/logos/virginia-cancer-specialists-pc.png)
Phone: 703-208-5390
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
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9280 W. Sunset Road
Suite 100
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
702.952.1251
![Comprehensive Cancer Centers of Nevada](/wp-content/uploads/logos/comprehensive-cancer-centers-of-nevada.jpg)
Phone: 702-952-3400
Comprehensive Cancer Centers of Nevada Comprehensive Cancer Centers of Nevada (CCCN) is the award-winning multidisciplinary...
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150 North Eagle Creek Drive
Lexington, Kentucky 40509
Lexington, Kentucky 40509
Phone: 720-874-1346
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94 Old Short Hills Road
Livingston, New Jersey 07039
Livingston, New Jersey 07039
Phone: 973-322-5325
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UCLA UCLA's primary purpose as a public research university is the creation, dissemination, preservation and...
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250 25th Ave N, Ste 100
Nashville, Tennessee 37023
Nashville, Tennessee 37023
615-320-5090
![Tennessee Oncology, PLLC](/wp-content/uploads/logos/tennessee-oncology-pllc.jpg)
Phone: 877-691-7274
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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433 Southwest 10th Street
Ocala, Florida 34471
Ocala, Florida 34471
Phone: 352-732-4938
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Tucson, Arizona 85704
Phone: 520-797-4468
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818 N. Emporia, #403
Wichita, Kansas 67214
Wichita, Kansas 67214
(316) 262-4467
![Cancer Center of Kansas](/wp-content/uploads/logos/cancer-center-of-kansas.jpg)
Phone: 316-262-4467
Cancer Center of Kansas The physicians of Cancer Center are hematologists and oncologists. The staff...
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