Risk Factors for Linezolid Resistance in Staphylococcus Aureus

This is a retrospective chart review study. The proposed study aims to document the risk
factors for quinolone resistance in bloodstream isolates of Klebsiella species. Additionally,
the adequacy of empiric antibiotic therapy for Klebsiella bloodstream infections will be
assessed. This research is important because identification of risk factors may allow earlier
initiation of appropriate therapy in patients infected with these bacteria. Additionally, we
will identify whether horizontal spread is responsible for this increasing trend.

Inclusion Criteria:

- patients with linezolid resistance to staphylococcus aureus

Exclusion Criteria:

- those that don't meet entry criteria